Bone marrow necrosis

Common Name(s)

Bone marrow necrosis

In bone marrow necrosis, there is poor circulation of oxygen and nutrients to the bone marrow cells, causing the cells to die. Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. Bone marrow necrosis often causes fever and bone pain, and is associated with blood cancers, in particular acute lymphoblastic leukemia (ALL) although it can be associated with other cancers and non-cancerous conditions (e.g., sickle cell anemia, tuberculosis, infection, and sepsis).
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Advocacy and Support Organizations Health Questions Recommended Apps Scientific Literature Symptoms, Diagnosis, and Treatment Clinical Trial Information
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone marrow necrosis" for support, advocacy or research.

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone marrow necrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
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Recommended Apps

Privately answer questions about your health. Let resources, you select, come to you

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

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Relief is when you and the right researcher find each other

Finding the right clinical trial for Bone marrow necrosis can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone marrow necrosis" returned 74 free, full-text research articles on human participants. First 3 results:

Bone marrow necrosis secondary to metastatic adenocarcinoma revealed by 18F-FDG PET/CT: A clinical case report.
 

Author(s): Ping Dong, Rong Tian, Lin Li, Minggang Su

Journal: Medicine (Baltimore). 2017 Dec;96(49):e9067.

 

Bone marrow necrosis (BMN) is a rare malignancy-associated hematologic disorder characterized by necrosis of myeloid and stromal marrow elements with preservation of cortical bone.

Last Updated: 31 Dec 1969

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[Tumor necrosis factor-α regulates the osteogenic differentiation of bone marrow mesenchymal stem cells in chronic periodontitis].
 

Author(s): Li Xiaoguang, Wang Yizhu, Guo Bin

Journal: Hua Xi Kou Qiang Yi Xue Za Zhi. 2017 Jun;35(3):334-338.

 

Bone marrow mesenchymal stem cells (BMSCs) and ideal adult stem cells for alveolar bone regeneration considerably help restore the structure and function of the periodontium and promote the healing of periodontal disease. Thus, BMSC features, especially the mechanism of osteogenic ...

Last Updated: 31 Dec 1969

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From Bone Marrow Necrosis to Gaucher Disease; A Long Way to Run.
 

Author(s): Neslihan Erdem, Ahmet Çizmecioğlu, İsmet Aydoğdu

Journal: Turk J Haematol. 2015 Dec;32(4):373-4.

 

Last Updated: 31 Dec 1969

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To view other free, full-text articles on human participants, please click on the link below.

PubMed Article Results at NCBI: 74 article(s)

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone marrow necrosis" returned 1 free, full-text review articles on human participants. First 3 results:

Successful treatment with rivaroxaban of cerebral venous thrombosis and bone marrow necrosis induced by pegaspargase: A case report and literature review.
 

Author(s): Jingrui Sui, Yongming Zhang, Liqing Yang, Hui Wang, Junqing Xu, Rongxia Wei, Yaping Hao, Xiaolei Wang, Jun Peng, Junjie Ma

Journal: Medicine (Baltimore). 2017 Nov;96(46):e8715.

 

Pegaspargase has been used in the treatment of acute lymphoblastic leukemia with promising results. However, it has also been associated with several potentially serious complications, including thrombosis. Pegaspargase-induced cerebral venous thrombosis and bone marrow necrosis are very rare.

Last Updated: 31 Dec 1969

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PubMed Review Results at NCBI: 1 review(s)

 
 
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Symptoms, Diagnosis, and Treatment

This information is provided by Genetics Home Reference.
https://ghr.nlm.nih.gov/condition/pearson-marrow-pancreas-syndrome
https://ghr.nlm.nih.gov/gene/TNFRSF11A
https://ghr.nlm.nih.gov/gene/ELANE
https://ghr.nlm.nih.gov/condition/osteopetrosis
https://ghr.nlm.nih.gov/condition/paget-disease-of-bone
https://ghr.nlm.nih.gov/gene/TNFRSF11B
https://ghr.nlm.nih.gov/gene/SH3BP2
https://ghr.nlm.nih.gov/condition/dyskeratosis-congenita
https://ghr.nlm.nih.gov/condition/ghosal-hematodiaphyseal-dysplasia
https://ghr.nlm.nih.gov/gene/NBEAL2
https://ghr.nlm.nih.gov/gene/MPL
https://ghr.nlm.nih.gov/gene/CXCR4
https://ghr.nlm.nih.gov/gene/JAK2
https://ghr.nlm.nih.gov/gene/TNFSF11
https://ghr.nlm.nih.gov/condition/sost-related-sclerosing-bone-dysplasia
https://ghr.nlm.nih.gov/gene/TET2
https://ghr.nlm.nih.gov/condition/ataxia-pancytopenia-syndrome
https://ghr.nlm.nih.gov/condition/gray-platelet-syndrome
https://ghr.nlm.nih.gov/condition/primary-myelofibrosis
https://ghr.nlm.nih.gov/gene/SAMD9L
Full Results at Genetics Home Reference: 714 matches

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Autologous Bone Marrow Derived Mesenchymal Stromal Cells Transplantation(BM-MSC) for Kienbock's Disease
 

Status: Recruiting

Condition Summary: Kienböck's Disease

 

Last Updated: 18 Jul 2016

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Clinical Trial of Use of Autologous Bone Marrow Stem Cells Seeded on Porous Tricalcium Phosphate Matrix and Demineralized Bone Matrix in Patients With Osteonecrosis
 

Status: Recruiting

Condition Summary: Osteonecrosis of Jaw

 

Last Updated: 29 Mar 2017

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Compare the Effects of Single Versus Repeated Intracoronary Application of Autologous Bone Marrow-derived Mononuclear Cells on Mortality in Patients With Chronic Post-infarction Heart Failure
 

Status: Recruiting

Condition Summary: Heart Failure

 

Last Updated: 20 Mar 2017

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According to ClinicalTrials.gov there are currently 5 additional "open" studies for "Bone marrow necrosis" (open studies are recruiting volunteers) and 69 "Bone marrow necrosis" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:
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Relief is when you and the right researcher find each other
Finding the right clinical trial for Bone marrow necrosis can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Learn More