Bone marrow necrosis

Common Name(s)

Bone marrow necrosis

In bone marrow necrosis, there is poor circulation of oxygen and nutrients to the bone marrow cells, causing the cells to die. Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. Bone marrow necrosis often causes fever and bone pain, and is associated with blood cancers, in particular acute lymphoblastic leukemia (ALL) although it can be associated with other cancers and non-cancerous conditions (e.g., sickle cell anemia, tuberculosis, infection, and sepsis).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone marrow necrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone marrow necrosis" returned 77 free, full-text research articles on human participants. First 3 results:

Bone marrow necrosis: ten-year retrospective review of bone marrow biopsy specimens.
 

Author(s): Geoffrey D Wool, Anne Deucher

Journal: Am. J. Clin. Pathol.. 2015 Feb;143(2):201-13; quiz 306.

 

Bone marrow can undergo necrosis for many different causes; malignant causes are reported to be more frequent.

Last Updated: 17 Jan 2015

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Epidermal growth factor attenuates tubular necrosis following mercuric chloride damage by regeneration of indigenous, not bone marrow-derived cells.
 

Author(s): Tzung-Hai Yen, Malcolm R Alison, Robert A Goodlad, William R Otto, Rosemary Jeffery, H Terence Cook, Nicholas A Wright, Richard Poulsom

Journal: J. Cell. Mol. Med.. 2015 Feb;19(2):463-73.

 

To assess effects of epidermal growth factor (EGF) and pegylated granulocyte colony-stimulating factor (P-GCSF; pegfilgrastim) administration on the cellular origin of renal tubular epithelium regenerating after acute kidney injury initiated by mercuric chloride (HgCl2 ). Female mice ...

Last Updated: 29 Jan 2015

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Efficacy of autologous bone marrow buffy coat grafting combined with core decompression in patients with avascular necrosis of femoral head: a prospective, double-blinded, randomized, controlled study.
 

Author(s): Yuanchen Ma, Tao Wang, Junxing Liao, Honglin Gu, Xinpeng Lin, Qing Jiang, Max K Bulsara, Minghao Zheng, Qiujian Zheng

Journal:

 

Avascular necrosis of femoral head (ANFH) is a progressive disease that often leads to hip joint dysfunction and even disability in young patients. Although the standard treatment, which is core decompression, has the advantage of minimal invasion, the efficacy is variable. Recent ...

Last Updated: 2 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone marrow necrosis" returned 1 free, full-text review articles on human participants. First 3 results:

The use of percutaneous autologous bone marrow transplantation in nonunion and avascular necrosis of bone.
 

Author(s): P Hernigou, A Poignard, O Manicom, G Mathieu, H Rouard

Journal: J Bone Joint Surg Br. 2005 Jul;87(7):896-902.

 

Last Updated: 23 Jun 2005

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Autologous Bone Marrow and BMP7 Treatment in the Necrosis in the Femoral Head of the Adult
 

Status: Recruiting

Condition Summary: Aseptic Necrosis of Femur Head

 

Last Updated: 11 Jan 2016

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Mesenchymal Stem Cells in Osteonecrosis of the Femoral Head
 

Status: Recruiting

Condition Summary: Avascular Necrosis of Femur Head

 

Last Updated: 10 Dec 2015

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Last Updated: 3 Jan 2016

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