Bone marrow necrosis

Common Name(s)

Bone marrow necrosis

In bone marrow necrosis, there is poor circulation of oxygen and nutrients to the bone marrow cells, causing the cells to die. Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. Bone marrow necrosis often causes fever and bone pain, and is associated with blood cancers, in particular acute lymphoblastic leukemia (ALL) although it can be associated with other cancers and non-cancerous conditions (e.g., sickle cell anemia, tuberculosis, infection, and sepsis).
Jump to Topic
Advocacy and Support Organizations Health Questions Recommended Apps Scientific Literature Symptoms, Diagnosis, and Treatment Clinical Trial Information
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone marrow necrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone marrow necrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

Recommended Apps

Privately answer questions about your health. Let resources, you select, come to you

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

Learn More
Relief is when you and the right researcher find each other

Finding the right clinical trial for Bone marrow necrosis can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

Learn More
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone marrow necrosis" returned 54 free, full-text research articles on human participants. First 3 results:

Toll-like receptor 7-stimulated tumor necrosis factor α causes bone marrow damage in systemic lupus erythematosus.
 

Author(s): Haoyang Zhuang, Shuhong Han, Yuan Xu, Yi Li, Hai Wang, Li-Jun Yang, Westley H Reeves

Journal: Arthritis Rheumatol. 2014 Jan;66(1):140-51.

 

To define the pathogenesis of bone marrow (BM) involvement in systemic lupus erythematosus (SLE).

Last Updated: 22 Jan 2014

Go To URL
Bone marrow necrosis: a culture medium for bacteria.
 

Author(s): Christophe Willekens, Thomas Boyer

Journal: Blood. 2013 Oct;122(16):2775.

 

Last Updated: 29 Nov 2013

Go To URL
HLA-B27 alters the response to tumor necrosis factor α and promotes osteoclastogenesis in bone marrow monocytes from HLA-B27-transgenic rats.
 

Author(s): Gerlinde Layh-Schmitt, Eva Y Yang, Grace Kwon, Robert A Colbert

Journal: Arthritis Rheum.. 2013 Aug;65(8):2123-31.

 

To determine whether HLA-B27 expression alters the response of bone marrow monocytes from HLA-B27/human β2 -microglobulin-transgenic (B27-Tg) rats to tumor necrosis factor α (TNFα) and, if so, whether this affects the cells involved in bone homeostasis.

Last Updated: 29 Jul 2013

Go To URL

To view other free, full-text articles on human participants, please click on the link below.

PubMed Article Results at NCBI: 54 article(s)

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone marrow necrosis" returned 2 free, full-text review articles on human participants. First 3 results:

[Chronic myeloid leukemia with bone marrow infection and necrosis: a case report and literature review].
 

Author(s): Yong-Yuan Dai, Xi-Mei Hu, Shui-Yang Zhou

Journal: Zhonghua Xue Ye Xue Za Zhi. 2012 Feb;33(2):145-6.

 

Last Updated: 26 Jun 2012

Go To URL
The use of percutaneous autologous bone marrow transplantation in nonunion and avascular necrosis of bone.
 

Author(s): P Hernigou, A Poignard, O Manicom, G Mathieu, H Rouard

Journal: J Bone Joint Surg Br. 2005 Jul;87(7):896-902.

 

Last Updated: 23 Jun 2005

Go To URL

To view other free, full-text review articles on human participants, please click on the link below.

PubMed Review Results at NCBI: 2 review(s)

 
 
Top

Symptoms, Diagnosis, and Treatment

This information is provided by Genetics Home Reference.
http://ghr.nlm.nih.gov/condition/dyskeratosis-congenita
Full Results at Genetics Home Reference: 4 matches

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Mesenchymal Stem Cells in Osteonecrosis of the Femoral Head
 

Status: Recruiting

Condition Summary: Avascular Necrosis of Femur Head

 

Last Updated: 22 Jan 2015

Go to URL
Evaluation of Mesenchymal Stem Cells to Treat Avascular Necrosis of the Hip
 

Status: Recruiting

Condition Summary: Avascular Necrosis of the Femoral Head

 

Last Updated: 14 Feb 2014

Go to URL
Study Into the Effect of Ibandronate for the Treatment of Bone Marrow Edema in Relation to Spontaneous or Non-traumatic Osteonecrosis of the Knee: A Randomized Double-blind, Placebo-controlled Trial
 

Status: Recruiting

Condition Summary: Osteonecrosis of the Knee; Bone Marrow Edema of the Knee

 

Last Updated: 9 Jul 2013

Go to URL
According to ClinicalTrials.gov there are currently 21 additional "open" studies for "Bone marrow necrosis" (open studies are recruiting volunteers) and 65 "Bone marrow necrosis" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:
TrialsFinder Branding Graphics
Relief is when you and the right researcher find each other
Finding the right clinical trial for Bone marrow necrosis can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Learn More