Bone marrow necrosis

Common Name(s)

Bone marrow necrosis

In bone marrow necrosis, there is poor circulation of oxygen and nutrients to the bone marrow cells, causing the cells to die. Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. Bone marrow necrosis often causes fever and bone pain, and is associated with blood cancers, in particular acute lymphoblastic leukemia (ALL) although it can be associated with other cancers and non-cancerous conditions (e.g., sickle cell anemia, tuberculosis, infection, and sepsis).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone marrow necrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone marrow necrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone marrow necrosis" returned 79 free, full-text research articles on human participants. First 3 results:

[Tumor necrosis factor-α regulates the osteogenic differentiation of bone marrow mesenchymal stem cells in chronic periodontitis].
 

Author(s): Li Xiaoguang, Wang Yizhu, Guo Bin

Journal: Hua Xi Kou Qiang Yi Xue Za Zhi. 2017 Jun;35(3):334-338.

 

Bone marrow mesenchymal stem cells (BMSCs) and ideal adult stem cells for alveolar bone regeneration considerably help restore the structure and function of the periodontium and promote the healing of periodontal disease. Thus, BMSC features, especially the mechanism of osteogenic ...

Last Updated: 4 Jul 2017

Go To URL
From Bone Marrow Necrosis to Gaucher Disease; A Long Way to Run.
 

Author(s): Neslihan Erdem, Ahmet Çizmecioğlu, İsmet Aydoğdu

Journal: Turk J Haematol. 2015 Dec;32(4):373-4.

 

Last Updated: 19 Jan 2016

Go To URL
Bone marrow necrosis in acute leukemia: Clinical characteristic and outcome.
 

Author(s): Talha Badar, Aditya Shetty, Carlos Bueso-Ramos, Jorge Cortes, Marina Konopleva, Gautam Borthakur, Sherry Pierce, Xuelin Huang, Hsiang-Chun Chen, Tapan Kadia, Naval Daver, Courtney Dinardo, Susan O'Brien, Guillermo Garcia-Manero, Hagop Kantarjian, Farhad Ravandi

Journal: Am. J. Hematol.. 2015 Sep;90(9):769-73.

 

Bone marrow necrosis (BMN) is characterized by infarction of the medullary stroma, leading to marrow necrosis with preserved cortical bone. In reported small series, BMN in hematological malignancies is associated with poor prognosis. We sought to find the impact of BMN on clinical ...

Last Updated: 21 Aug 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone marrow necrosis" returned 1 free, full-text review articles on human participants. First 3 results:

The use of percutaneous autologous bone marrow transplantation in nonunion and avascular necrosis of bone.
 

Author(s): P Hernigou, A Poignard, O Manicom, G Mathieu, H Rouard

Journal: J Bone Joint Surg Br. 2005 Jul;87(7):896-902.

 

Last Updated: 23 Jun 2005

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 18 Jul 2016

Go to URL
Effect of BM-MSCs on Early Graft Function Recovery After DCD Kidney Transplant.
 

Status: Not yet recruiting

Condition Summary: Kidney Transplantation; Acute Kidney Tubular Necrosis

 

Last Updated: 28 Sep 2015

Go to URL
Effect of BM-MSCs in DCD Kidney Transplantation
 

Status: Not yet recruiting

Condition Summary: Kidney Transplantation; Acute Kidney Tubular Necrosis

 

Last Updated: 25 Sep 2015

Go to URL