Bone marrow necrosis

Common Name(s)

Bone marrow necrosis

In bone marrow necrosis, there is poor circulation of oxygen and nutrients to the bone marrow cells, causing the cells to die. Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. Bone marrow necrosis often causes fever and bone pain, and is associated with blood cancers, in particular acute lymphoblastic leukemia (ALL) although it can be associated with other cancers and non-cancerous conditions (e.g., sickle cell anemia, tuberculosis, infection, and sepsis).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone marrow necrosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone marrow necrosis" returned 56 free, full-text research articles on human participants. First 3 results:

Bone marrow necrosis in de novo AML.
 

Author(s): Michael Daskalakis, Marcelo Caballero

Journal: Blood. 2014 Apr;123(14):2137.

 

Last Updated: 12 May 2014

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[A patient with acute mononuclear leukemia 9 months after bone marrow necrosis].
 

Author(s): Jiaming Tang, Guohua Liang, Xiaoyun Chen

Journal: Zhonghua Xue Ye Xue Za Zhi. 2014 Jan;35(1):39.

 

Last Updated: 7 Mar 2014

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Toll-like receptor 7-stimulated tumor necrosis factor α causes bone marrow damage in systemic lupus erythematosus.
 

Author(s): Haoyang Zhuang, Shuhong Han, Yuan Xu, Yi Li, Hai Wang, Li-Jun Yang, Westley H Reeves

Journal: Arthritis Rheumatol. 2014 Jan;66(1):140-51.

 

To define the pathogenesis of bone marrow (BM) involvement in systemic lupus erythematosus (SLE).

Last Updated: 22 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone marrow necrosis" returned 2 free, full-text review articles on human participants. First 3 results:

[Chronic myeloid leukemia with bone marrow infection and necrosis: a case report and literature review].
 

Author(s): Yong-Yuan Dai, Xi-Mei Hu, Shui-Yang Zhou

Journal: Zhonghua Xue Ye Xue Za Zhi. 2012 Feb;33(2):145-6.

 

Last Updated: 26 Jun 2012

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The use of percutaneous autologous bone marrow transplantation in nonunion and avascular necrosis of bone.
 

Author(s): P Hernigou, A Poignard, O Manicom, G Mathieu, H Rouard

Journal: J Bone Joint Surg Br. 2005 Jul;87(7):896-902.

 

Last Updated: 23 Jun 2005

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mesenchymal Stem Cells in Osteonecrosis of the Femoral Head
 

Status: Recruiting

Condition Summary: Avascular Necrosis of Femur Head

 

Last Updated: 16 Jul 2015

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Evaluation of Mesenchymal Stem Cells to Treat Avascular Necrosis of the Hip
 

Status: Recruiting

Condition Summary: Avascular Necrosis of the Femoral Head

 

Last Updated: 14 Feb 2014

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