Stroke 1

Common Name(s)

Stroke 1

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Stroke 1" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Stroke 1" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Stroke 1" returned 157 free, full-text research articles on human participants. First 3 results:

Increase of circulating miR-223 and insulin-like growth factor-1 is associated with the pathogenesis of acute ischemic stroke in patients.
 

Author(s): Yang Wang, Yu Zhang, Jun Huang, Xiaoyan Chen, Xiang Gu, Yongting Wang, Lili Zeng, Guo-Yuan Yang

Journal:

 

The relationship between circulating microRNA-223 and pathogenesis of acute ischemic stroke is unknown. Here we investigated the roles and possible targets of circulating microRNA-223 in human ischemic stroke within the first 72 hours.

Last Updated: 10 Apr 2014

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Increased force variability in chronic stroke: contributions of force modulation below 1 Hz.
 

Author(s): Neha Lodha, Gaurav Misra, Stephen A Coombes, Evangelos A Christou, James H Cauraugh

Journal:

 

Increased force variability constitutes a hallmark of arm disabilities following stroke. Force variability is related to the modulation of force below 1 Hz in healthy young and older adults. However, whether the increased force variability observed post stroke is related to the modulation ...

Last Updated: 3 Jan 2014

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Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants.
 

Author(s): , Yuan Lu, Kaveh Hajifathalian, Majid Ezzati, Mark Woodward, Eric B Rimm, Goodarz Danaei

Journal: Lancet. 2014 Mar;383(9921):970-83.

 

Body-mass index (BMI) and diabetes have increased worldwide, whereas global average blood pressure and cholesterol have decreased or remained unchanged in the past three decades. We quantified how much of the effects of BMI on coronary heart disease and stroke are mediated through ...

Last Updated: 17 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Stroke 1" returned 14 free, full-text review articles on human participants. First 3 results:

Mitochondrial dysfunction induced by nuclear poly(ADP-ribose) polymerase-1: a treatable cause of cell death in stroke.
 

Author(s): Paul Baxter, Yanting Chen, Yun Xu, Raymond A Swanson

Journal: Transl Stroke Res. 2014 Feb;5(1):136-44.

 

Many drugs targeting excitotoxic cell death have demonstrated robust neuroprotective effects in animal models of cerebral ischemia. However, these neuroprotective effects have almost universally required drug administration at relatively short time intervals after ischemia onset. ...

Last Updated: 5 Feb 2014

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High-mobility group box 1: an amplifier of stem and progenitor cell activity after stroke.
 

Author(s): Kazuhide Hayakawa, Loc-Duyen D Pham, Ken Arai, Eng H Lo

Journal: Acta Neurochir. Suppl.. 2013 ;118():31-8.

 

Stroke induces a highly complex web of pathophysiology that usually leads to serious long-term -disability. Molecules from the damage-associated molecular pattern (DAMP) family immediately increase after stroke. DAMPs are known to cause massive inflammation and brain damage. Thus, ...

Last Updated: 8 Apr 2013

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Review, historical context, and clarifications of the NINDS rt-PA stroke trials exclusion criteria: Part 1: rapidly improving stroke symptoms.
 

Author(s): , Steven R Levine, Pooja Khatri, Joseph P Broderick, James C Grotta, Scott E Kasner, Doojin Kim, Brett C Meyer, Peter Panagos, Jose Romano, Phillip Scott,

Journal: Stroke. 2013 Sep;44(9):2500-5.

 

Since Food and Drug Administration approval of intravenous tissue-type plasminogen activator (tPA) for treatment of acute ischemic stroke in 1996, it has become clear that several criteria used for exclusion from therapy were not based on actual data or operationally defined for use ...

Last Updated: 27 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of HMGB-1 in Chronic Stroke
 

Status: Recruiting

Condition Summary: Cerebrovascular Accident; Cerebral Stroke; Stroke, Acute

 

Last Updated: 23 Sep 2014

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Efficacy of BNG-1 to Treat Acute Ischemic Stroke
 

Status: Recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 5 Aug 2013

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Prehospital COOLing 1 (PreCOOL 1)
 

Status: Recruiting

Condition Summary: Stroke

 

Last Updated: 21 Jun 2013

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