Sarcoidosis 1

Common Name(s)

Sarcoidosis 1

Sarcoidosis is a granulomatous disorder associated with an accumulation of CD4+ T cells and a Th1 immune response. In childhood, 2 distinct types of sarcoidosis have been described ({15:Shetty and Gedalia, 1998}). Usually the disease is detected in older children by chest radiography, and the clinical manifestations are characterized by a classic triad of lung, lymph node, and eye involvement, similar to those in adults. In contrast, early-onset sarcoidosis (EOS; {609464}), which usually appears in those younger than 4 years of age, is rare and has a distinct triad of skin, joint, and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, EOS is progressive and in many cases causes severe complications, such as blindness, joint destruction, and visceral involvement.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis 1" for support, advocacy or research.

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Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

Last Updated: 19 Feb 2013

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

Last Updated: 2 Mar 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Sarcoidosis 1" for support, advocacy or research.

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Foundation for Sarcoidosis Research

The Foundation for Sarcoidosis Research is the nation's leading nonprofit organization dedicated to finding a cure for this disease and to improving care for sarcoidosis patients. Since its establishment in 2000, FSR has funded numerous domestic and international research efforts and worked diligently to provide resources to thousands.

http://www.stopsarcoidosis.org

Last Updated: 19 Feb 2013

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Sarcoidosis Australia

Bring fellow sufferers together to support each other and their families Provide and share information and experiences, acting as a forum to help those affected to understand the condition Support the medical profession in the early diagnosis and treatment of those with these diseases Support the medical profession in research into the disease Heighten awareness of the disease in Australia

http://www.sarcoidosisaustralia.com

Last Updated: 2 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Sarcoidosis 1" returned 38 free, full-text research articles on human participants. First 3 results:

Is there an association between clinical presentation and the location and extent of myocardial involvement of cardiac sarcoidosis as assessed by ¹⁸F- fluorodoexyglucose positron emission tomography?
 

Author(s): Brian A Mc Ardle, David H Birnie, Ran Klein, Rob A de Kemp, Eugene Leung, Jennifer Renaud, Jean DaSilva, George A Wells, Rob S Beanlands, Pablo B Nery

Journal: Circ Cardiovasc Imaging. 2013 Sep;6(5):617-26.

 

Positron emission tomography using (18)F-Fluorodeoxyglucose (FDG) is an emerging modality for diagnosis of cardiac sarcoidosis (CS). We compared the location and degree of FDG uptake in CS patients presenting with either advanced atrioventricular block (AVB) or ventricular tachycardia (VT).

Last Updated: 18 Sep 2013

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Triggering receptor expressed on myeloid cells-1 and 2 in bronchoalveolar lavage fluid in pulmonary sarcoidosis.
 

Author(s): Magda Suchankova, Maria Bucova, Elena Tibenska, Eva Tedlova, Juraj Demian, Ivan Majer, Helena Novosadova, Miroslav Tedla, Ema Paulovicova, Daniela Kantarova

Journal: Respirology. 2013 Apr;18(3):455-62.

 

Pulmonary sarcoidosis (PS) is characterized by the formation of granulomas in the lungs and has been associated with infection by microorganisms. Triggering receptor expressed on the surface of myeloid cells (TREM)-1 is overexpressed in response to infection while TREM-2 is involved ...

Last Updated: 22 Mar 2013

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Pleomorphic cutaneous sarcoidosis confined to lesions of vitiligo vulgaris in a patient with type 1 diabetes mellitus.
 

Author(s): Namrata Chhabra, Deepika Pandhi, Prashant Verma, Archana Singal

Journal: Indian J Dermatol Venereol Leprol. ;78(6):754-6.

 

Last Updated: 18 Oct 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Sarcoidosis 1" returned 1 free, full-text review articles on human participants. First 3 results:

Primary care paradigm for management of sarcoidosis, Part 1.
 

Author(s): R C Young, R E Rachal, B Nelson-Knuckles, C N Arthur, H V Nevels

Journal: J Natl Med Assoc. 1997 Mar;89(3):181-90.

 

Sarcoidosis is a systemic granulomatous disease of undetermined etiology in which the immune system is overstimulated. Management of the patient with sarcoidosis entails continuity of patient care far beyond disease, even into remission. Care is comprehensive, including all involved ...

Last Updated: 7 May 1997

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
 

Status: Recruiting

Condition Summary: Emphysema; Chronic Obstructive Pulmonary Disease (COPD); Cystic Fibrosis; Pulmonary Fibrosis; Bronchiectasis; Sarcoidosis; Pulmonary Hypertension; Alpha-1 Antitrypsin Deficiency

 

Last Updated: 6 Aug 2014

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Genomic Research in Sarcoidosis
 

Status: Recruiting

Condition Summary: Sarcoidosis

 

Last Updated: 10 Jan 2014

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A Trial on Clinical Efficacy of 1% Versus 2% Lignocaine in Cough Suppression and Pain Relief in Patients Undergoing Flexible Bronchoscopy
 

Status: Recruiting

Condition Summary: Lung Cancer; Tuberculosis; Sarcoidosis; Interstitial Lung Disease

 

Last Updated: 3 Jun 2014

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