Renal dysplasia

Common Name(s)

Renal dysplasia

Autosomal recessive renal tubular dysgenesis is a severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype) ({5:Gribouval et al., 2005}). Absence or paucity of differentiated proximal tubules is the histopathologic hallmark of the disorder and may be associated with skull ossification defects.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal dysplasia" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal dysplasia" returned 100 free, full-text research articles on human participants. First 3 results:

Renal dysplasia characterized by prominent cartilaginous metaplasia lesions in VACTERL association: A case report.
 

Author(s): Takeo Nakaya, Taiju Hyuga, Yukichi Tanaka, Shina Kawai, Hideo Nakai, Toshiro Niki, Akira Tanaka

Journal: Medicine (Baltimore). 2017 Apr;96(15):e6499.

 

Renal dysplasia is the most important cause of end-stage renal disease in children. The histopathological characteristic of dysplasia is primitive tubules with fibromuscular disorganization. Renal dysplasia often includes metaplastic cartilage. Metaplastic cartilage in renal dysplasia ...

Last Updated: 13 Apr 2017

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Clinical Auditory Phenotypes Associated with GATA3 Gene Mutations in Familial Hypoparathyroidism-deafness-renal Dysplasia Syndrome.
 

Author(s): Li Wang, Qiong-Fen Lin, Hong-Yang Wang, Jing Guan, Lan Lan, Lin-Yi Xie, Lan Yu, Ju Yang, Cui Zhao, Jin-Long Liang, Han-Lin Zhou, Huan-Ming Yang, Wen-Ping Xiong, Qiu-Jing Zhang, Da-Yong Wang, Qiu-Ju Wang

Journal: Chin. Med. J.. 2017 Mar;130(6):703-709.

 

Hypoparathyroidism-deafness-renal dysplasia (HDR) syndrome is an autosomal dominant disorder primarily caused by haploinsufficiency of GATA binding protein 3 (GATA3) gene mutations, and hearing loss is the most frequent phenotypic feature. This study aimed at identifying the causative ...

Last Updated: 17 Mar 2017

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Acute renal infarction resulting from fibromuscular dysplasia: a case report.
 

Author(s): Harri Juhani Saarinen, Ari Palomäki

Journal:

 

Acute abdominal pain is one of the most frequent complaints evaluated at emergency departments. Approximately 25 % of abdominal pain patients discharged from emergency departments are diagnosed with undifferentiated abdominal pain. One possible reason for acute abdominal pain is ...

Last Updated: 10 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Renal dysplasia" returned 10 free, full-text review articles on human participants. First 3 results:

Renal Fibromuscular Dysplasia: A Not So Common Entity of Secondary Hypertension.
 

Author(s): Elias A Sanidas, Maria Seferou, Dimitris P Papadopoulos, Anastasios Makris, Nora A Viniou, Vasiliki Chantziara, Vasiliki Cennimata, Vasilios Papademetriou

Journal: J Clin Hypertens (Greenwich). 2016 Mar;18(3):240-6.

 

Fibromuscular dysplasia is a rare noninflammatory vascular disease characterized by nonatheroslerotic stenosis predominantly seen in young women, whereas the majority of cases involve the renal arteries causing secondary hypertension. Most noninvasive screening tests are not quite ...

Last Updated: 13 Mar 2016

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Renal dysplasia in the neonate.
 

Author(s): Yu L Phua, Jacqueline Ho

Journal: Curr. Opin. Pediatr.. 2016 Apr;28(2):209-15.

 

Renal dysplasia is classically described as a developmental disorder whereby the kidneys fail to undergo appropriate differentiation, resulting in the presence of malformed renal tissue elements. It is the commonest cause of chronic kidney disease and renal failure in the neonate. ...

Last Updated: 11 Mar 2016

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Fibromuscular dysplasia affecting a two-branched renal artery in a patient with a solitary kidney: case presentation.
 

Author(s): Xuanqi An, Xiongjing Jiang, Hui Dong, Meng Peng, Yubao Zou, Lei Song, Ting Guan, Xianliang Zhou, Yuejin Yang

Journal: Clin Cardiol. 2013 Aug;36(8):E7-10.

 

Fibromuscular dysplasia (FMD) is a nonatherosclerotic, noninflammatory arterial disease, commonly involving the renal arteries. Here we report a case of a 16-year-old Chinese male who was found to have severe hypertension with proteinuria for 2 years. Computed tomography showed absence ...

Last Updated: 16 Sep 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ambulatory Blood Pressure Measurement in Children With Congenital Urine Flow Obstruction
 

Status: Available

Condition Summary: Hydronephrosis; Multicystic-Dysplastic Kidney

 

Last Updated: 1 Oct 2008

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CTT on Renogram as an Early Marker of Significant Obstruction in Uretero-pelvic Junction Syndrome
 

Status: Not yet recruiting

Condition Summary: Ureteropelvic Junction Obstruction

 

Last Updated: 17 Jan 2017

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Indwelling Double-J Ureteral Stent Versus Externalized Modified-Salle Stent for Pyeloplasty
 

Status: Recruiting

Condition Summary: Ureteropelvic Junction Obstruction

 

Last Updated: 13 Sep 2016

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