Pseudoexfoliation glaucoma

Common Name(s)

Pseudoexfoliation glaucoma

Exfoliation syndrome (XFS) is a common age-related disorder of the extracellular matrix that is frequently associated with severe chronic secondary open-angle glaucoma and cataract. XFS syndrome may affect up to 30% of people over 60 years of age worldwide and is biomicroscopically diagnosed by abnormal microfibrillar deposits on ocular structures that line the aqueous-bathed surfaces of the anterior segment (summary by {19:Schlotzer-Schrehardt and Naumann, 2006}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pseudoexfoliation glaucoma" for support, advocacy or research.

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The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

Last Updated: 19 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pseudoexfoliation glaucoma" for support, advocacy or research.

Logo
The Glaucoma Foundation

The mission of The Glaucoma Foundation (TGF) is to fund groundbreaking research and to educate the public about the disease and the importance of early detection to prevent blindness.

http://www.glaucomafoundation.org

Last Updated: 19 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pseudoexfoliation glaucoma" returned 28 free, full-text research articles on human participants. First 3 results:

Association of known common genetic variants with primary open angle, primary angle closure, and pseudoexfoliation glaucoma in Pakistani cohorts.
 

Author(s): Shazia Micheal, Humaira Ayub, Muhammad Imran Khan, Bjorn Bakker, Frederieke E Schoenmaker-Koller, Mahmood Ali, Farah Akhtar, Wajid Ali Khan, Raheel Qamar, Anneke I den Hollander

Journal:

 

Despite the different etiology of primary open angle glaucoma (POAG), primary angle closure glaucoma (PACG), and pseudoexfoliative glaucoma (PEXG), several studies have suggested that these forms of glaucoma have overlapping genetic risk factors. Therefore, the aim of this study was ...

Last Updated: 9 Dec 2014

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Association of LOXL1 polymorphisms with pseudoexfoliation, glaucoma, intraocular pressure, and systemic diseases in a Greek population. The Thessaloniki eye study.
 

Author(s): Eleftherios Anastasopoulos, Anne L Coleman, M Roy Wilson, Janet S Sinsheimer, Fei Yu, Sokratis Katafigiotis, Panayiota Founti, Angeliki Salonikiou, Theofanis Pappas, Archimidis Koskosas, Theodora Katopodi, Alexandros Lambropoulos, Fotis Topouzis

Journal:

 

To investigate the association of the two single-nucleotide polymorphisms (SNPs) in the lysyl oxidase-like 1 (LOXL1) gene with pseudoexfoliation syndrome (PEX), pseudoexfoliative glaucoma (PEXG), and primary open-angle glaucoma (POAG) in a Greek population-based setting, from the ...

Last Updated: 12 Jul 2014

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Association between polymorphisms in lysyl oxidase-like 1 and susceptibility to pseudoexfoliation syndrome and pseudoexfoliation glaucoma.
 

Author(s): Jun-Zhou Tang, Xiu-Qing Wang, Hua-Feng Ma, Fa-Feng Ma, Bo Wang, Peng-Fei Wang, Zhi-Xi Peng, Xi-Yuan Zhou

Journal:

 

The present knowledge on the association of single nucleotide polymorphisms (SNPs) of lysyl oxidase-like 1 (LOXL1) with pseudoexfoliation syndrome (PEXS) and pseudoexfoliation glaucoma (PEXG) is controversial and inconclusive. This meta-analysis sought to derive a more precise estimation ...

Last Updated: 7 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pseudoexfoliation glaucoma" returned 1 free, full-text review articles on human participants. First 3 results:

The medical and surgical management of pseudoexfoliation glaucoma.
 

Author(s): Manishi A Desai, Richard K Lee

Journal: Int Ophthalmol Clin. 2008 ;48(4):95-113.

 

Last Updated: 21 Oct 2008

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Imaging Lens Deposits in Exfoliation Syndrome
 

Status: Recruiting

Condition Summary: Exfoliation Syndrome; Primary Open Angle Glaucoma; Cataracts

 

Last Updated: 5 Mar 2015

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LOXL1 Polymorphism in Pseudoexfoliation Syndrome
 

Status: Recruiting

Condition Summary: Pseudoexfoliation Syndrome

 

Last Updated: 23 Jan 2012

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The Diurnal and Nocturnal Effect of Simbrinza and Timolol on Intraocular Pressure and Ocular Perfusion Pressure
 

Status: Recruiting

Condition Summary: Open Angle Glaucoma; Ocular Hypertension; Pigment Dispersion Syndrome; Pseudoexfoliation Glaucoma

 

Last Updated: 8 Jul 2015

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