Parkinson disease 2

Common Name(s)

Parkinson disease 2

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Parkinson disease 2" for support, advocacy or research.

American Parkinson Disease Association

As the country’s largest grassroots Parkinson’s disease organization, the American Parkinson Disease Association (APDA) improves the lives people with Parkinson’s disease and their families from coast to coast with patient/caregiver support; education and positive lifestyle programs; awareness, social and fundraising events; and scientific research funding at all levels. Through a national network of Chapters, Information & Referral Centers, more than 1,000 support groups, and eight Centers for Advanced Research, APDA delivers help for today and hope for tomorrow.

Last Updated: 23 Oct 2014

View Details
National Parkinson Foundation

The National Parkinson Foundation is the only organization with a singular focus on improving the quality of Parkinson's care through research, education and outreach. We continue to bring help and hope to the estimated one million individuals in the US, four to six million worldwide, who are living with Parkinson's disease. NPF has funded more than $180 million in research and support services to improve the lives of people with PD. NPF programs touch more than one million people a year through our global network of Centers of Excellence, our US chapters, conferences, and online resources.

Last Updated: 23 Apr 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Parkinson disease 2" for support, advocacy or research.

American Parkinson Disease Association

As the country’s largest grassroots Parkinson’s disease organization, the American Parkinson Disease Association (APDA) improves the lives people with Parkinson’s disease and their families from coast to coast with patient/caregiver support; education and positive lifestyle programs; awareness, social and fundraising events; and scientific research funding at all levels. Through a national network of Chapters, Information & Referral Centers, more than 1,000 support groups, and eight Centers for Advanced Research, APDA delivers help for today and hope for tomorrow.

http://www.apdaparkinson.org

Last Updated: 23 Oct 2014

View Details
National Parkinson Foundation

The National Parkinson Foundation is the only organization with a singular focus on improving the quality of Parkinson's care through research, education and outreach. We continue to bring help and hope to the estimated one million individuals in the US, four to six million worldwide, who are living with Parkinson's disease. NPF has funded more than $180 million in research and support services to improve the lives of people with PD. NPF programs touch more than one million people a year through our global network of Centers of Excellence, our US chapters, conferences, and online resources.

http://parkinson.org

Last Updated: 23 Apr 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

Aware in Care

Aware in Care aims to help people with Parkinson’s disease get the best care possible during a hospital stay.

Updated 8 Apr 2014

Go To URL
What You and Your Family Should Know

This book offers a basic overview of Parkinson’s disease. Topics include symptoms, diagnosis, parkinsonism, treatment options, putting your health team together, accepting and adapting to PD, and staying well.

Updated 23 Apr 2014

Go To URL
Caring and Coping

Written for care partners of people with Parkinson’s, this book profiles caregiver roles and activities. Topics include what to expect, care options, activities of daily living, legal and financial planning and taking care of yourself as caregiver.

Updated 23 Apr 2014

Go To URL
Fitness Counts

Exercise is important at any stage of Parkinson’s. This book describes exercise methods that contribute to stability and includes photos to demonstrate proper form.

Updated 23 Apr 2014

Go To URL
10 Early Warning Signs of Parkinson's Disease

This short brochure describes 10 symptoms that may be early signs of Parkinson’s disease. Each symptom of concern is listed along with what is "normal." If you have more than one symptom, you may want to visit your doctor.

Updated 23 Apr 2014

Go To URL
Medications

This book describes both motor and non-motor symptoms of Parkinson’s and provides detailed information on common medications used to treat these symptoms.

Updated 23 Apr 2014

Go To URL
Nutrition Matters

This book focuses on optimal nutrition for people with Parkinson’s and explains how PD affects the gastrointestinal system. It also offers tips and recipes to help manage non-motor symptoms and medication side effects.

Updated 23 Apr 2014

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Parkinson disease 2" returned 14 free, full-text research articles on human participants. First 3 results:

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
 

Author(s): Alexandria Beilina, Iakov N Rudenko, Alice Kaganovich, Laura Civiero, Hien Chau, Suneil K Kalia, Lorraine V Kalia, Evy Lobbestael, Ruth Chia, Kelechi Ndukwe, Jinhui Ding, Mike A Nalls, , , Maciej Olszewski, David N Hauser, Ravindran Kumaran, Andres M Lozano, Veerle Baekelandt, Lois E Greene, Jean-Marc Taymans, Elisa Greggio, Mark R Cookson

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2014 Feb;111(7):2626-31.

 

Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a risk factor for sporadic PD. Using protein-protein interaction arrays, we identified BCL2-associated athanogene 5, Rab7L1 (RAB7, member RAS oncogene family-like ...

Last Updated: 19 Feb 2014

Go To URL
Is Parkinson disease associated with lysosomal integral membrane protein type-2?: challenges in interpreting association data.
 

Author(s): Emerson Maniwang, Nahid Tayebi, Ellen Sidransky

Journal: Mol. Genet. Metab.. 2013 Apr;108(4):269-71.

 

Several genetic risk factors have been identified for Parkinson disease (PD), including mutations in glucocerebrosidase (GBA1). Recently, two single nucleotide polymorphisms (SNPs) described as SCARB2 SNPs were reported to be associated with PD. SCARB2 is an attractive candidate gene ...

Last Updated: 13 Mar 2013

Go To URL
Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.
 

Author(s): Prachi Bajpai, Michelle C Sangar, Shilpee Singh, Weigang Tang, Seema Bansal, Goutam Chowdhury, Qian Cheng, Ji-Kang Fang, Martha V Martin, F Peter Guengerich, Narayan G Avadhani

Journal: J. Biol. Chem.. 2013 Feb;288(6):4436-51.

 

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxic side product formed in the chemical synthesis of desmethylprodine opioid analgesic, which induces Parkinson disease. Monoamine oxidase B, present in the mitochondrial outer membrane of glial cells, catalyzes the oxidation ...

Last Updated: 11 Feb 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Parkinson disease 2" returned 1 free, full-text review articles on human participants. First 3 results:

α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of Parkinson disease.
 

Author(s): Jason P Covy, Benoit I Giasson

Journal: Neurotoxicology. 2011 Oct;32(5):622-9.

 

Parkinson disease (PD) is the most common movement disorder. It is characterized by bradykinesia, postural instability, resting tremor, and rigidity associated with the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Another pathological hallmark of ...

Last Updated: 24 Oct 2011

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Mutations Associated With Parkinson s Disease
 

Status: Recruiting

Condition Summary: Parkinson's Disease

 

Last Updated: 1 Oct 2014

Go to URL

Last Updated: 18 Sep 2013

Go to URL
Clinical, Molecular and by Neuroimaging of LRRK2 Mutations
 

Status: Recruiting

Condition Summary: Parkinson's Disease

 

Last Updated: 26 Sep 2012

Go to URL