Pancreatic cancer 4

Common Name(s)

Pancreatic cancer 4

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 4" for support, advocacy or research.

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 4" for support, advocacy or research.

Logo
Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer 4" returned 24 free, full-text research articles on human participants. First 3 results:

Impact of FOLFIRINOX compared with gemcitabine on quality of life in patients with metastatic pancreatic cancer: results from the PRODIGE 4/ACCORD 11 randomized trial.
 

Author(s): Sophie Gourgou-Bourgade, Caroline Bascoul-Mollevi, Françoise Desseigne, Marc Ychou, Olivier Bouché, Rosine Guimbaud, Yves Bécouarn, Antoine Adenis, Jean-Luc Raoul, Valérie Boige, Jocelyne Bérille, Thierry Conroy

Journal: J. Clin. Oncol.. 2013 Jan;31(1):23-9.

 

To compare the quality of life (QoL) of patients receiving oxaliplatin, irinotecan, fluorouracil, and leucovorin (FOLFIRINOX) or gemcitabine as first-line chemotherapy and to assess whether pretreatment QoL predicts survival in patients with metastatic pancreatic cancer.

Last Updated: 31 Dec 2012

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Novel involvement of leukotriene B₄ receptor 2 through ERK activation by PP2A down-regulation in leukotriene B₄-induced keratin phosphorylation and reorganization of pancreatic cancer cells.
 

Author(s): Mi Kyung Park, Youngran Park, Jaegal Shim, Hye Ja Lee, Sanghee Kim, Chang Hoon Lee

Journal: Biochim. Biophys. Acta. 2012 Dec;1823(12):2120-9.

 

Perinuclear reorganization via phosphorylation of specific serine residues in keratin is involved in the deformability of metastatic cancer cells. The level of leukotriene B₄ is high in pancreatic cancers. However, the roles of LTB₄ and its cognate receptors in keratin reorganization ...

Last Updated: 5 Nov 2012

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CDK-4 inhibitor P276 sensitizes pancreatic cancer cells to gemcitabine-induced apoptosis.
 

Author(s): Dharmalingam Subramaniam, Giridharan Periyasamy, Sivapriya Ponnurangam, Debarshi Chakrabarti, Aravind Sugumar, Muralidhara Padigaru, Scott J Weir, Arun Balakrishnan, Somesh Sharma, Shrikant Anant

Journal: Mol. Cancer Ther.. 2012 Jul;11(7):1598-608.

 

Despite advances in molecular pathogenesis, pancreatic cancer remains a major unsolved health problem. It is a rapidly invasive, metastatic tumor that is resistant to standard therapies. The phosphatidylinositol-3-kinase/Akt and mTOR signaling pathways are frequently dysregulated ...

Last Updated: 9 Jul 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer 4" returned 6 free, full-text review articles on human participants. First 3 results:

Clinical outcome of pancreatic cancer patients with diabetes mellitus: is diabetes a poor prognostic factor? Highlights from the "2010 ASCO Annual Meeting". Chicago, IL, USA. June 4-8, 2010.
 

Author(s): Soonmo Peter Kang, Muhammad Wasif Saif

Journal:

 

Diabetes mellitus and its related factors such as hyperinsulinemia have been linked to various cancer risks and outcomes. Previous research has offered inconsistent results in terms of relationship between diabetes and pancreatic cancers. Establishing clear association between these ...

Last Updated: 5 Jul 2010

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Pancreatic cancer and thrombosis. Highlights from the "2010 ASCO Annual Meeting". Chicago, IL, USA. June 4-8, 2010.
 

Author(s): Manasi M Shah, Mumhammad Wasif Saif

Journal:

 

Although pancreatic cancer is recognized as a major risk factor for venous thromboembolism, the exact magnitude of the problem is not known. The incidence varies from 17% to 57% depending on different studies. The effect of venous thromboembolism on outcomes in not well defined and ...

Last Updated: 5 Jul 2010

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Updates in locally advanced pancreatic cancer. Highlights from the "2010 ASCO Annual Meeting". Chicago, IL, USA. June 4-8, 2010.
 

Author(s): Bryan W Chang, Eduardo Siccion, Muhammad Wasif Saif

Journal:

 

Pancreatic cancer is the 4th leading cancer cause mortality in both men and women. Pancreatic cancer is usually diagnosed in the advanced setting, and only 10-15% of patients present with operable disease. About 25% are locally advanced and unresectable and the rest are metastatic. ...

Last Updated: 5 Jul 2010

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

In Vivo Assessment of Hypoxia in Gastro-intestinal Cancer Using 18F-HX4-PET: an Optimization and Reproducibility Study
 

Status: Recruiting

Condition Summary: Pancreatic Cancer; Esophageal Cancer; Rectal Cancer

 

Last Updated: 21 Nov 2013

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Early (4 Days) Versus Standard Drainage of the Abdominal Cavity After Pancreaticoduodenectomy
 

Status: Recruiting

Condition Summary: Pancreatic Disease; Pancreatic Neoplasms

 

Last Updated: 19 Dec 2011

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Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study)
 

Status: Recruiting

Condition Summary: Early Pancreatic Neoplasia; Familial Pancreatic Neoplasia

 

Last Updated: 5 Dec 2013

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