Pancreatic cancer 3

Common Name(s)

Pancreatic cancer 3

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 3" for support, advocacy or research.

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 3" for support, advocacy or research.

Logo
Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer 3" returned 124 free, full-text research articles on human participants. First 3 results:

Expression and Prognostic Value of Indoleamine 2,3-dioxygenase in Pancreatic Cancer.
 

Author(s): Tao Zhang, Xiang-Long Tan, Yong Xu, Zi-Zheng Wang, Chao-Hui Xiao, Rong Liu

Journal: Chin. Med. J.. 2017 Mar;130(6):710-716.

 

Indoleamine 2,3-dioxygenase (IDO), an enzyme for tryptophan metabolism through the kynurenine pathway, exhibits an immunosuppressive effect and induces immune tolerance in tumor cells. The effects of IDO on pancreatic cancer are poorly understood. This study aimed to investigate the ...

Last Updated: 17 Mar 2017

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Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer.
 

Author(s): Maria Laura Pati, John R Hornick, Mauro Niso, Francesco Berardi, Dirk Spitzer, Carmen Abate, William Hawkins

Journal:

 

Despite considerable efforts by scientific research, pancreatic cancer is the fourth leading cause of cancer related mortalities. Sigma-2 receptors, which are overexpressed in several tumors, represent promising targets for triggering selective pancreatic cancer cells death.

Last Updated: 14 Jan 2017

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Efficacy and safety profile of nab-paclitaxel plus gemcitabine in patients with metastatic pancreatic cancer treated to disease progression: a subanalysis from a phase 3 trial (MPACT).
 

Author(s): Arndt Vogel, Josefine Römmler-Zehrer, Jack Shiansong Li, Desmond McGovern, Alfredo Romano, Michael Stahl

Journal:

 

The phase 3 MPACT trial in patients with metastatic pancreatic cancer demonstrated superior efficacy of nab-paclitaxel (nab-P) + gemcitabine (Gem) vs Gem monotherapy for all endpoints examined including overall survival, the primary endpoint. In the MPACT trial, patients were ...

Last Updated: 22 Oct 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer 3" returned 10 free, full-text review articles on human participants. First 3 results:

Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer.
 

Author(s): Chiara Birtolo, Vay Liang W Go, Andrzej Ptasznik, Guido Eibl, Stephen J Pandol

Journal: Pancreas. 2016 Jan;45(1):21-31.

 

Even though a strong association between inflammation and cancer has been widely accepted, the underlying precise molecular mechanisms are still largely unknown. A complex signaling network between tumor and stromal cells is responsible for the infiltration of inflammatory cells into ...

Last Updated: 15 Dec 2015

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Circulating Leptin and Risk of Pancreatic Cancer: A Pooled Analysis From 3 Cohorts.
 

Author(s): Rachael Z Stolzenberg-Solomon, Christina C Newton, Debra T Silverman, Michael Pollak, Leticia M Nogueira, Stephanie J Weinstein, Demetrius Albanes, Satu Männistö, Eric J Jacobs

Journal: Am. J. Epidemiol.. 2015 Aug;182(3):187-97.

 

Adiposity is associated with pancreatic cancer; however, the underlying mechanism(s) is uncertain. Leptin is an adipokine involved in metabolic regulation, and obese individuals have higher concentrations. We conducted a pooled, nested case-control study of cohort participants from ...

Last Updated: 29 Jul 2015

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Curcumin and omega-3 fatty acids enhance NK cell-induced apoptosis of pancreatic cancer cells but curcumin inhibits interferon-γ production: benefits of omega-3 with curcumin against cancer.
 

Author(s): Milan Fiala

Journal:

 

STAT-3 and STAT-1 signaling have opposite effects in oncogenesis with STAT-3 acting as an oncogene and STAT-1 exerting anti-oncogenic activities through interferon-γ and interferon-α. The cytokine IL-6 promotes oncogenesis by stimulation of NFκB and STAT-3 signaling. Curcuminoids ...

Last Updated: 17 Feb 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 24 Nov 2016

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