Pancreatic cancer 3

Common Name(s)

Pancreatic cancer 3

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 3" for support, advocacy or research.

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 3" for support, advocacy or research.

Logo
Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer 3" returned 99 free, full-text research articles on human participants. First 3 results:

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α.
 

Author(s): Romain Baer, Célia Cintas, Marlène Dufresne, Stéphanie Cassant-Sourdy, Nina Schönhuber, Laetitia Planque, Hubert Lulka, Bettina Couderc, Corinne Bousquet, Barbara Garmy-Susini, Bart Vanhaesebroeck, Stéphane Pyronnet, Dieter Saur, Julie Guillermet-Guibert

Journal: Genes Dev.. 2014 Dec;28(23):2621-35.

 

Increased PI 3-kinase (PI3K) signaling in pancreatic ductal adenocarcinoma (PDAC) correlates with poor prognosis, but the role of class I PI3K isoforms during its induction remains unclear. Using genetically engineered mice and pharmacological isoform-selective inhibitors, we found ...

Last Updated: 2 Dec 2014

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Application of 3.0 tesla magnetic resonance imaging for diagnosis in the orthotopic nude mouse model of pancreatic cancer.
 

Author(s): Li Wu, Chen Wang, Xiuzhong Yao, Kai Liu, Yanjun Xu, Haitao Zhang, Caixia Fu, Xiaolin Wang, Yingyi Li

Journal: Exp. Anim.. 2014 ;63(4):403-13.

 

The aim of this study was to successfully establish an orthotopic murine model using two different human pancreatic adenocarcinoma cell lines and to propose a 3.0 tesla MRI protocol for noninvasive characterization of this model. SW1990 and MIAPaca-2 tumor cells were injected into ...

Last Updated: 30 Oct 2014

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Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine.
 

Author(s): Orkhan Isayev, Vanessa Rausch, Nathalie Bauer, Li Liu, Pei Fan, Yiyao Zhang, Jury Gladkich, Clifford C Nwaeburu, Jürgen Mattern, Martin Mollenhauer, Felix Rückert, Sebastian Zach, Uwe Haberkorn, Wolfgang Gross, Frank Schönsiegel, Alexandr V Bazhin, Ingrid Herr

Journal: Oncotarget. 2014 Jul;5(13):5177-89.

 

According to the cancer stem cell (CSC) hypothesis, the aggressive growth and early metastasis of pancreatic ductal adenocarcinoma (PDA) is due to the activity of CSCs, which are not targeted by current therapies. Otto Warburg suggested that the growth of cancer cells is driven by ...

Last Updated: 1 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer 3" returned 7 free, full-text review articles on human participants. First 3 results:

Pathophysiological roles of Pim-3 kinase in pancreatic cancer development and progression.
 

Author(s): Ying-Yi Li, Naofumi Mukaida

Journal: World J. Gastroenterol.. 2014 Jul;20(28):9392-404.

 

Pim-3 is a member of the provirus integration site for Moloney murine leukemia virus (Pim) family proteins that exhibit serine/threonine kinase activity. Similar to the other Pim kinases (Pim-1 and Pim-2), Pim-3 is involved in many cellular processes, including cell proliferation, ...

Last Updated: 29 Jul 2014

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Fish or long-chain (n-3) PUFA intake is not associated with pancreatic cancer risk in a meta-analysis and systematic review.
 

Author(s): Bo Qin, Pengcheng Xun, Ka He

Journal: J. Nutr.. 2012 Jun;142(6):1067-73.

 

Long-chain (n-3) PUFA (LC-PUFA) have been hypothesized to be beneficial in preventing pancreatic carcinogenesis, but the associations of fish or LC-PUFA intake with pancreatic cancer found in epidemiologic studies have been controversial and inconclusive. To estimate the overall association ...

Last Updated: 21 May 2012

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Palliative care of pancreatic cancer. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011.
 

Author(s): Muhammad Wasif Saif

Journal:

 

Pancreatic cancer is one of the most fatal malignancies. Palliative care represents an important aspect of management in patients with pancreatic malignancy. Identifying and treating disease related symptoms are very important. As a physician taking care of these patients it is essential ...

Last Updated: 8 Jul 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting
 

Status: Recruiting

Condition Summary: 2nd-line, 3rd-line and Greater Metastatic Pancreatic Cancer

 

Last Updated: 16 Jun 2015

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Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer)
 

Status: Recruiting

Condition Summary: Colorectal Cancer; Cancer of Pancreas; Pancreatic Neoplasm; Malignant Neoplasm of Large Intestine; Malignant Tumor of Colon; Colon Carcinoma; Cancer of Colon; Pancreatic Cancer

 

Last Updated: 24 Mar 2015

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