Pancreatic cancer 2

Common Name(s)

Pancreatic cancer 2

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 2" for support, advocacy or research.

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 2" for support, advocacy or research.

Logo
Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer 2" returned 230 free, full-text research articles on human participants. First 3 results:

Stemness and anti-cancer drug resistance in ATP-binding cassette subfamily G member 2 highly expressed pancreatic cancer is induced in 3D culture conditions.
 

Author(s): Norihiko Sasaki, Toshiyuki Ishiwata, Fumio Hasegawa, Masaki Michishita, Hiroki Kawai, Yoko Matsuda, Tomio Arai, Naoshi Ishikawa, Junko Aida, Kaiyo Takubo, Masashi Toyoda

Journal: Cancer Sci.. 2018 Apr;109(4):1135-1146.

 

The expression of ATP-binding cassette subfamily G member 2 (ABCG2) is related to tumorigenic cancer stem cells (CSC) in several cancers. However, the effects of ABCG2 on CSC-related malignant characteristics in pancreatic ductal adenocarcinoma (PDAC) are not well elucidated. In this ...

Last Updated: 31 Dec 1969

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Grainyhead-like 2 (GRHL2) regulates epithelial plasticity in pancreatic cancer progression.
 

Author(s): Hitoe Nishino, Shigetsugu Takano, Hideyuki Yoshitomi, Kensuke Suzuki, Shingo Kagawa, Reiri Shimazaki, Hiroaki Shimizu, Katsunori Furukawa, Masaru Miyazaki, Masayuki Ohtsuka

Journal: Cancer Med. 2017 Nov;6(11):2686-2696.

 

The epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) contribute to cancer metastasis of pancreatic ductal adenocarcinoma (PDAC). We explored the role of grainyhead-like 2 (GRHL2), a suppressor of EMT, in the progression of PDAC. Expressions of GRHL2 ...

Last Updated: 31 Dec 1969

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The Role of Obesity, Type 2 Diabetes, and Metabolic Factors in Pancreatic Cancer: A Mendelian Randomization Study.
 

Author(s): Robert Carreras-Torres, Mattias Johansson, Valerie Gaborieau, Philip C Haycock, Kaitlin H Wade, Caroline L Relton, Richard M Martin, George Davey Smith, Paul Brennan

Journal: J. Natl. Cancer Inst.. 2017 Sep;109(9):.

 

Risk factors for pancreatic cancer include a cluster of metabolic conditions such as obesity, hypertension, dyslipidemia, insulin resistance, and type 2 diabetes. Given that these risk factors are correlated, separating out causal from confounded effects is challenging. Mendelian ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer 2" returned 6 free, full-text review articles on human participants. First 3 results:

Mitochondrial uncoupling protein 2 and pancreatic cancer: a new potential target therapy.
 

Author(s): Massimo Donadelli, Ilaria Dando, Elisa Dalla Pozza, Marta Palmieri

Journal: World J. Gastroenterol.. 2015 Mar;21(11):3232-8.

 

Overall 5-years survival of pancreatic cancer patients is nearly 5%, making this cancer type one of the most lethal neoplasia. Furthermore, the incidence rate of pancreatic cancer has a growing trend that determines a constant increase in the number of deceases caused by this pathology. ...

Last Updated: 31 Dec 1969

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Involvement of eicosanoids in the pathogenesis of pancreatic cancer: the roles of cyclooxygenase-2 and 5-lipoxygenase.
 

Author(s): Lawrence M Knab, Paul J Grippo, David J Bentrem

Journal: World J. Gastroenterol.. 2014 Aug;20(31):10729-39.

 

The interplay between inflammation and cancer progression is a growing area of research. A combination of clinical, epidemiological, and basic science investigations indicate that there is a relationship between inflammatory changes in the pancreas and neoplastic progression. Diets ...

Last Updated: 31 Dec 1969

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Therapeutic targeting of pancreatic cancer utilizing sigma-2 ligands.
 

Author(s): John R Hornick, Dirk Spitzer, Peter Goedegebuure, Robert H Mach, William G Hawkins

Journal: Surgery. 2012 Sep;152(3 Suppl 1):S152-6.

 

One major barrier in the development of pancreas cancer therapeutics is the selective delivery of the drugs to their cellular targets. We have previously developed several sigma-2 ligands and reported the discovery of a component of the receptor for these ligands. Several sigma-2 ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Screening for PDAC in BRCA1/2 Patients
 

Status: Recruiting

Condition Summary: Pancreatic Cancer

 

Last Updated: 8 Apr 2016

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Last Updated: 2 May 2018

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Last Updated: 27 Oct 2017

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