Pancreatic cancer 1

Common Name(s)

Pancreatic cancer 1

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 1" for support, advocacy or research.

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer 1" for support, advocacy or research.

Logo
Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer 1" returned 252 free, full-text research articles on human participants. First 3 results:

Randomised phase II trial of S-1 plus oxaliplatin vs S-1 in patients with gemcitabine-refractory pancreatic cancer.
 

Author(s): S Ohkawa, T Okusaka, H Isayama, A Fukutomi, K Yamaguchi, M Ikeda, A Funakoshi, M Nagase, Y Hamamoto, S Nakamori, Y Tsuchiya, H Baba, H Ishii, Y Omuro, M Sho, S Matsumoto, N Yamada, H Yanagimoto, M Unno, Y Ichikawa, S Takahashi, G Watanabe, G Wakabayashi, N Egawa, M Tsuda, R Hosotani, C Hamada, I Hyodo

Journal: Br. J. Cancer. 2015 Apr;112(9):1428-34.

 

This randomised, open-label, multicenter phase II study compared progression-free survival (PFS) of S-1 plus oxaliplatin (SOX) with that of S-1 alone in patients with gemcitabine-refractory pancreatic cancer.

Last Updated: 29 Apr 2015

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Anti-tumor effect of the extract from qingyihuaji formula on pancreatic cancer by down-regulating Notch-4 and Jagged-1.
 

Author(s): Yanli Xu, Feiye Zhu, Shan Xu, Luming Liu

Journal: J Tradit Chin Med. 2015 Feb;35(1):77-83.

 

To investigate, in terms of Notch signaling pathway, the effect on pancreatic cancer of the extract of an anti-tumor prescription--Qingyi-huaji formula (QYHJ)--from Traditional Chinese Medicine (TCM).

Last Updated: 6 Apr 2015

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Transcriptional silencing of ETS-1 abrogates epithelial-mesenchymal transition resulting in reduced motility of pancreatic cancer cells.
 

Author(s): Chunyan Li, Zhonghan Wang, Yan Chen, Min Zhou, Haijun Zhang, Rong Chen, Fangfang Shi, Cailian Wang, Zongdao Rui

Journal: Oncol. Rep.. 2015 Feb;33(2):559-65.

 

v-ets erythroblastosis virus E26 oncogene homolog 1 (ETS-1) plays crucial roles in a spectrum of malignancies. ETS-1 has gained attention in cancer research for its importance in cell migration, invasion and proliferation. In the present study, we focused on the effect of ETS-1 on ...

Last Updated: 22 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer 1" returned 5 free, full-text review articles on human participants. First 3 results:

S-1 in the treatment of pancreatic cancer.
 

Author(s): Kentaro Sudo, Kazuyoshi Nakamura, Taketo Yamaguchi

Journal: World J. Gastroenterol.. 2014 Nov;20(41):15110-8.

 

S-1 is an oral 5-fluorouracil (5-FU) prodrug, which is designed to improve the antitumor activity of 5-FU by inhibiting dihydropyrimidine dehydrogenase, the key enzyme of 5-FU catabolism. Recently, two important studies on the clinical use of S-1 for pancreatic cancer have been reported ...

Last Updated: 11 Nov 2014

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Involvement of substance P and the NK-1 receptor in pancreatic cancer.
 

Author(s): Miguel Muñoz, Rafael Coveñas

Journal: World J. Gastroenterol.. 2014 Mar;20(9):2321-34.

 

Pancreatic cancer is the fourth leading cause of cancer related-death for both men and women and the 1- and 5-year relative survival rates are 25% and 6%, respectively. Thus, it is urgent to investigate new antitumor drugs to improve the survival of pancreatic cancer patients. The ...

Last Updated: 7 Mar 2014

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Significance of caveolin-1 regulators in pancreatic cancer.
 

Author(s): Tao Chen, Liang Liu, Hua-Xiang Xu, Wen-Quan Wang, Chun-Tao Wu, Wan-Tong Yao, Xian-Jun Yu

Journal: Asian Pac. J. Cancer Prev.. 2013 ;14(8):4501-7.

 

Caveolin-1 is a scaffold protein on the cell membrane. As the main component of caveolae, caveolin-1 is involved in many biological processes that include substance uptake and transmembrane signaling. Many of these processes and thus caveolin-1 contribute to cell transformation, tumorigenesis, ...

Last Updated: 2 Oct 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Gemcitabine and Oxaliplatin in the Management of Metastatic Pancreatic Cancers With Low Expression of ERCC1
 

Status: Recruiting

Condition Summary: Metastatic Pancreatic Cancer; ERCC1

 

Last Updated: 30 Jan 2012

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Pancreatic Cancer Early Detection Program
 

Status: Recruiting

Condition Summary: Pancreatic Cancer; Pancreas Cancer; Pancreatic Adenocarcinoma; Familial Pancreatic Cancer; BRCA 1/2; HNPCC; Lynch Syndrome; Hereditary Pancreatitis; FAMMM; Familial Atypical Multiple Mole Melanoma; Peutz Jeghers Syndrome

 

Last Updated: 30 Jul 2014

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Nab-paclitaxel Plus S-1 in Patients With Advanced Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Advanced Pancreatic Cancer

 

Last Updated: 12 Aug 2014

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