Ovarian hyperstimulation syndrome

Common Name(s)

Ovarian hyperstimulation syndrome

Ovarian hyperstimulation syndrome (OHSS) is a disorder that usually is caused by taking hormonalmedications to stimulate the development of eggs in the ovaries. In OHSS, the ovaries become swollen and painful. Symptoms usually present within 10 days after taking the medications, though the severity of symptoms varies and may worsen or improve over time. Moderate symptoms include nausea, vomiting, diarrhea, abdominal bloating, mild abdominal pain, or tenderness in the ovary areas. Severe symptoms include dark urine, decreased urinary frequency, shortness of breath, severe abdominal pain, rapid weight gain, tight or enlarged abdomen, or dizziness.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian hyperstimulation syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian hyperstimulation syndrome" returned 99 free, full-text research articles on human participants. First 3 results:

First mutation in the FSHR cytoplasmic tail identified in a non-pregnant woman with spontaneous ovarian hyperstimulation syndrome.
 

Author(s): Justine Hugon-Rodin, Charlotte Sonigo, Anne Gompel, Catherine Dodé, Michael Grynberg, Nadine Binart, Isabelle Beau

Journal:

 

Spontaneous ovarian hyperstimulation syndrome (sOHSS) is a rare event occurring mostly during natural pregnancy. Among described etiologies, some activating mutations of FSH receptor (FSHR) have been identified.

Last Updated: 27 Apr 2017

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Sliding scale HCG trigger yields equivalent pregnancy outcomes and reduces ovarian hyperstimulation syndrome: Analysis of 10,427 IVF-ICSI cycles.
 

Author(s): Vinay Gunnala, Alexis Melnick, Mohamad Irani, David Reichman, Glenn Schattman, Owen Davis, Zev Rosenwaks

Journal:

 

To evaluate pregnancy outcomes and the incidence of ovarian hyperstimulation syndrome (OHSS) using a sliding scale hCG protocol to trigger oocyte maturity and establish a threshold level of serum b-hCG associated with optimal oocyte maturity.

Last Updated: 25 Apr 2017

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PIVET rFSH dosing algorithms for individualized controlled ovarian stimulation enables optimized pregnancy productivity rates and avoidance of ovarian hyperstimulation syndrome.
 

Author(s): John L Yovich, Birgit Alsbjerg, Jason L Conceicao, Peter M Hinchliffe, Kevin N Keane

Journal:

 

The first PIVET algorithm for individualized recombinant follicle stimulating hormone (rFSH) dosing in in vitro fertilization, reported in 2012, was based on age and antral follicle count grading with adjustments for anti-Müllerian hormone level, body mass index, day-2 FSH, and smoking ...

Last Updated: 26 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian hyperstimulation syndrome" returned 14 free, full-text review articles on human participants. First 3 results:

Pharmacologic Interventions in Preventing Ovarian Hyperstimulation Syndrome: A Systematic Review and Network Meta-Analysis.
 

Author(s): Jun-Liang Guo, Duo-Duo Zhang, Yue Zhao, Dan Zhang, Xi-Meng Zhang, Can-Quan Zhou, Shu-Zhong Yao

Journal:

 

Ovarian hyperstimulation syndrome (OHSS) is a severe iatrogenic complication of controlled ovarian stimulation. Randomised controlled trials (RCTs) have proven several pharmacologic interventions to be effective in OHSS prevention, but these trials have seldom compared multiple drugs. ...

Last Updated: 12 Jan 2016

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Severe ovarian hyperstimulation syndrome complicated by Stenotrophomonas maltophilia peritonitis: a case report and literature review.
 

Author(s): Abdul Rehman, Noor Ul-Ain Baloch, Muhammad Awais

Journal: Intern. Med.. 2015 ;54(9):1149-52.

 

Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic disorder resulting from ovulation induction. Although the occurrence of this disorder is rare, it can be potentially life-threatening in its most severe forms. We herein present the case of a young nulliparous woman who presented ...

Last Updated: 7 May 2015

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Ovarian hyperstimulation syndrome: pathophysiology, staging, prediction and prevention.
 

Author(s): C O Nastri, D M Teixeira, R M Moroni, V M S Leitão, W P Martins

Journal: Ultrasound Obstet Gynecol. 2015 Apr;45(4):377-93.

 

To identify, appraise and summarize the current evidence regarding the pathophysiology, staging, prediction and prevention of ovarian hyperstimulation syndrome (OHSS).

Last Updated: 2 Apr 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy and Safety of Dexamethasone Prevention for Patients of Ovarian Hyperstimulation Syndrome
 

Status: Not yet recruiting

Condition Summary: Ovarian Hyperstimulation Syndrome

 

Last Updated: 24 Jul 2016

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The Influence of Timing of Cabergoline Initiation on Prevention of OHSS
 

Status: Recruiting

Condition Summary: Ovarian Hyperstimulation Syndrome

 

Last Updated: 21 Feb 2017

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Ovarian Hyperstimulation Syndrome in Patients Triggered by GnRH Agonist for Excessive Follicular Response
 

Status: Recruiting

Condition Summary: Ovarian Hyperstimulation Syndrome; Hypercoagulability

 

Last Updated: 22 Aug 2017

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