Bowen's disease

Common Name(s)

Bowen's disease, Squamous cell carcinoma in situ

Bowen’s disease is a curable abnormal tumor growth of the skin and is considered to be an early stage of squamous cell carcinoma (cancer affecting epithelial cells, the top layer of your skin). Symptoms include a growing red, scaly patch with an irregular border. The red patches may be itchy and occasionally may be sore and bleed. Sometimes the red area may be raised. While the patches can occur anywhere on the body, they most commonly show up on the lower leg and rarely arise on your palms or soles. Bowen’s disease may be caused by sun damage, arsenic exposure, chronic skin injuries, suppressed immune systems (such as AIDS or due to medications after an organ transplant), viral infections (HPV), and other skin disorders. Bowen's disease is more common in women than men, and usually affects older people in their 70s-80s. It tends to be seen on people who have had lots of sun exposure (one of the main causes), especially those with fair skin.

Diagnosis is usually made by a skin sample (biopsy) taken by a doctor. Treatment includes local chemotherapy, photodynamic treatment (using non-toxic light), and freezing the growth. Since these growths have not yet reached the deeper skin layers, Bowen's disease has a better prognosis and is more easily cured than more invasive forms of skin cancer. Please see your doctor or a dermatologist, if you are experiencing any of these symptoms for early diagnosis. If you or a family member has been diagnosed with Bowen’s disease, talk with your doctor or dermatologist about current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bowen's disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bowen's disease" returned 43 free, full-text research articles on human participants. First 3 results:

Pigmented Bowen's disease of the penis and scrotum in a patient with AIDS.
 

Author(s): Najla A Al-Dawsari, Wasim Raslan, M Fawaz Dawamneh

Journal:

 

Patients with HIV have higher risk of developing squamous cell carcinoma of the skin given the increased risk of HPV infection, which alters cell proliferation and apoptosis [1]. Pigmented Bowen's disease is an uncommon form of squamous cell carcinoma in-situ characterized by pigmented ...

Last Updated: 21 Apr 2014

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Sebaceous carcinoma associated with Bowen's disease: a case report with emphasis on the pathogenesis of sebaceous carcinoma.
 

Author(s): Mitsuaki Ishida, Muneo Iwai, Keiko Yoshida, Akiko Kagotani, Hidetoshi Okabe

Journal:

 

Last Updated: 2 Dec 2013

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Immunosuppressive and cytotoxic cells in invasive vs. non-invasive Bowen's disease.
 

Author(s): Sadanori Furudate, Taku Fujimura, Yumi Kambayashi, Takahiro Haga, Akira Hashimoto, Setsuya Aiba

Journal: Acta Derm. Venereol.. 2014 May;94(3):337-9.

 

Last Updated: 7 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bowen's disease" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effects of Arsenic on Keratinocytes in a Skin Equivalent Model
 

Status: Recruiting

Condition Summary: Bowen Disease

 

Last Updated: 20 Dec 2005

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