Osteoporosis

Common Name(s)

Osteoporosis

Osteoporosis is a condition that causes bones to become weak and brittle. Bone is living tissue that is constantly being broken down and replaced. When you are young, your body typically makes new bone faster than it breaks down old bone. This leads to dense bone mass (strong bones). When the creation of new bone is unable to keep up with the removal of old bone, they become weak and brittle. If osteoporosis is severe enough, a crack or break (fracture) within the bone can occur from something as minor as a fall or even from a normal action, like coughing. Symptoms of osteoporosis may include back pain, decrease in height, a hunched posture, and increased risk of bone fractures.

Most people reach their peak bone mass by their early 20s. Individuals with a high peak bone mass when they are young have a lower chance of developing osteoporosis as they age. Gender, age, and race are all risk factors for developing osteoporosis. Women, individuals who are white or of Asian descent, and the elderly have an increased risk of developing osteoporosis. Low calcium intake, eating disorders, and gastrointestinal surgery can also cause a greater risk for osteoporosis. Certain medications, especially steroids, as well as tobacco use, excessive alcohol consumption and a sedentary lifestyle all increase the risk for osteoporosis.

Specific types of X-ray images, called DXA scans, may be used to determine your bone density and diagnose osteoporosis. There are many forms of treatment, depending on the severity. It is important to talk to your doctor, if you or someone you know has been diagnosed with osteoporosis, to review the current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteoporosis" returned 2442 free, full-text research articles on human participants. First 3 results:

Prevalence of osteoporosis and related lifestyle and metabolic factors of postmenopausal women and elderly men: A cross-sectional study in Gansu province, Northwestern of China.
 

Author(s): Limin Tian, Ruifei Yang, Lianhua Wei, Jing Liu, Yan Yang, Feifei Shao, Wenjuan Ma, Tingting Li, Yu Wang, Tiankang Guo

Journal: Medicine (Baltimore). 2017 Oct;96(43):e8294.

 

The aim of this study was to investigate the osteoporosis prevalence and the risks of postmenopausal women and elderly men in Gansu province.This cross-sectional study involved 3359 postmenopausal women and 3205 elderly males who were randomly selected from 7 areas in Gansu province. ...

Last Updated: 25 Oct 2017

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How frequent is osteogenesis imperfecta in patients with idiopathic osteoporosis?: Case reports.
 

Author(s): Ali Al Kaissi, Christian Windpassinger, Farid Ben Chehida, Maher Ben Ghachem, Nabil M Nassib, Vladimir Kenis, Eugene Melchenko, Ekatrina Morenko, Sergey Ryabykh, Jochen G Hofstaetter, Franz Grill, Rudolf Ganger, Susanne Gerit Kircher

Journal: Medicine (Baltimore). 2017 Sep;96(35):e7863.

 

The term idiopathic osteoporosis itself is quite a non-specific disease label, which fails to address the etiological understanding. Bone mineral density alone is not a reliable parameter to detect patients at high risk of fracture. The diversity of the clinical phenotypes of discolored ...

Last Updated: 31 Aug 2017

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Identification of novel genetic loci for osteoporosis and/or rheumatoid arthritis using cFDR approach.
 

Author(s): Rou Zhou, Xu Lin, Ding-You Li, Xia-Fang Wang, Jonathan Greenbaum, Yuan-Cheng Chen, Chun-Ping Zeng, Jun-Min Lu, Zeng-Xing Ao, Lin-Ping Peng, Xiao Chun Bai, Jie Shen, Hong-Wen Deng

Journal:

 

There are co-morbidity between osteoporosis (OP) and rheumatoid arthritis (RA). Some genetic risk factors have been identified for these two phenotypes respectively in previous research; however, they accounted for only a small portion of the underlying total genetic variances. Here, ...

Last Updated: 30 Aug 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteoporosis" returned 663 free, full-text review articles on human participants. First 3 results:

Moxibustion treatment for primary osteoporosis: A systematic review of randomized controlled trials.
 

Author(s): Fanping Xu, Minghua Huang, Yi Jin, Qingzhe Kong, Zhongmin Lei, Xu Wei

Journal:

 

Primary osteoporosis (POP) has a serious impact on quality of life for middle-aged and elderly, which particularly increase the risk of fracture. We conducted the systematic review to evaluate the effects of moxibustion for POP in randomized controlled trials (RCTs).Eight databases ...

Last Updated: 7 Jun 2017

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Osteoporosis: the current status of mesenchymal stem cell-based therapy.
 

Author(s): Jitrada Phetfong, Tanwarat Sanvoranart, Kuneerat Nartprayut, Natakarn Nimsanor, Kanokwan Seenprachawong, Virapong Prachayasittikul, Aungkura Supokawej

Journal:

 

Osteoporosis, or bone loss, is a progressive, systemic skeletal disease that affects millions of people worldwide. Osteoporosis is generally age related, and it is underdiagnosed because it remains asymptomatic for several years until the development of fractures that confine daily ...

Last Updated: 24 May 2017

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The importance of physical function to people with osteoporosis.
 

Author(s): C Kerr, C Bottomley, S Shingler, L Giangregorio, H M de Freitas, C Patel, S Randall, D T Gold

Journal: Osteoporos Int. 2017 May;28(5):1597-1607.

 

There is increasing need to understand patient outcomes in osteoporosis. This article discusses that fracture in osteoporosis can lead to a cycle of impairment, driven by complex psychosocial factors, having a profound impact on physical function/activity which accumulates over time. ...

Last Updated: 7 Mar 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Jun 2016

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Multicenter Cohort Study on Osteoporosis
 

Status: Not yet recruiting

Condition Summary: Osteoporosis

 

Last Updated: 4 Nov 2016

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Study of Male Osteoporosis and Aging
 

Status: Recruiting

Condition Summary: Osteoporosis

 

Last Updated: 19 Apr 2007

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