Osteoporosis

Common Name(s)

Osteoporosis

Osteoporosis is a condition that causes bones to become weak and brittle. Bone is living tissue that is constantly being broken down and replaced. When you are young, your body typically makes new bone faster than it breaks down old bone. This leads to dense bone mass (strong bones). When the creation of new bone is unable to keep up with the removal of old bone, they become weak and brittle. If osteoporosis is severe enough, a crack or break (fracture) within the bone can occur from something as minor as a fall or even from a normal action, like coughing. Symptoms of osteoporosis may include back pain, decrease in height, a hunched posture, and increased risk of bone fractures.

Most people reach their peak bone mass by their early 20s. Individuals with a high peak bone mass when they are young have a lower chance of developing osteoporosis as they age. Gender, age, and race are all risk factors for developing osteoporosis. Women, individuals who are white or of Asian descent, and the elderly have an increased risk of developing osteoporosis. Low calcium intake, eating disorders, and gastrointestinal surgery can also cause a greater risk for osteoporosis. Certain medications, especially steroids, as well as tobacco use, excessive alcohol consumption and a sedentary lifestyle all increase the risk for osteoporosis.

Specific types of X-ray images, called DXA scans, may be used to determine your bone density and diagnose osteoporosis. There are many forms of treatment, depending on the severity. It is important to talk to your doctor, if you or someone you know has been diagnosed with osteoporosis, to review the current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteoporosis" returned 2265 free, full-text research articles on human participants. First 3 results:

Osteoporosis in Saudi Arabia.
 

Author(s): Ali S Jawad

Journal: Saudi Med J. 2016 Apr;37(4):468.

 

Last Updated: 7 Apr 2016

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Differential Item Functioning in the SF-36 Physical Functioning and Mental Health Sub-Scales: A Population-Based Investigation in the Canadian Multicentre Osteoporosis Study.
 

Author(s): Lisa M Lix, Xiuyun Wu, Wilma Hopman, Nancy Mayo, Tolulope T Sajobi, Juxin Liu, Jerilynn C Prior, Alexandra Papaioannou, Robert G Josse, Tanveer E Towheed, K Shawn Davison, Richard Sawatzky

Journal:

 

Self-reported health status measures, like the Short Form 36-item Health Survey (SF-36), can provide rich information about the overall health of a population and its components, such as physical, mental, and social health. However, differential item functioning (DIF), which arises ...

Last Updated: 22 Mar 2016

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Oral Bisphosphonates and Upper Gastrointestinal Cancer Risks in Asians with Osteoporosis: A Nested Case-Control Study Using National Retrospective Cohort Sample Data from Korea.
 

Author(s): Sun-Young Jung, Hyun Soon Sohn, Eun-Ja Park, Hae Sun Suh, Ji-Won Park, Jin-Won Kwon

Journal:

 

Bisphosphonate can irritate the gastrointestinal mucosa and increase the risk of esophageal or gastric cancer. The relatively high prevalence of upper gastrointestinal cancers and the widespread use of bisphosphonate in Korea call for further investigation. We conducted a case-control ...

Last Updated: 4 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteoporosis" returned 632 free, full-text review articles on human participants. First 3 results:

Osteoporosis in Gastrointestinal Diseases.
 

Author(s): Iwona Krela-Kaźmierczak, Aleksandra Szymczak, Liliana Łykowska-Szuber, Piotr Eder, Krzysztof Linke

Journal: Adv Clin Exp Med. ;25(1):185-90.

 

Secondary osteoporosis occurs as an isolated pathology or co-exists with types I and II osteoporosis. The gastroenterologist may come across osteoporosis or osteopenia in a patient with a gastrointestinal disease. This is often a young patient in whom investigations should be carried ...

Last Updated: 3 Mar 2016

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Chronic Psychological Stress as a Risk Factor of Osteoporosis.
 

Author(s): Kagaku Azuma, Yasuhiro Adachi, Haruki Hayashi, Kin-Ya Kubo

Journal: J. UOEH. 2015 Dec;37(4):245-53.

 

Osteoporosis, the most common metabolic skeletal disease, is characterized by decreased bone mass and deteriorated bone quality, leading to increased fracture risk. With the aging of the population, osteoporotic fracture is an important public health issue. Organisms are constantly ...

Last Updated: 15 Dec 2015

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Efficacy and Safety of Denosumab in Postmenopausal Women With Osteoporosis: A Meta-Analysis.
 

Author(s): Hai-Feng Gu, Ling-Jia Gu, Yue Wu, Xiao-Hong Zhao, Qing Zhang, Zhe-Rong Xu, Yun-Mei Yang

Journal: Medicine (Baltimore). 2015 Nov;94(44):e1674.

 

The purpose of this study was to perform a meta-analysis to examine the efficacy and safety of denosumab in postmenopausal women with osteoporosis.Medline, Cochrane Library, EMBASE, and Google Scholar databases were searched until October 30, 2014 using combinations of the following ...

Last Updated: 11 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Osteoporosis Coordinator for Low Volume Community Hospitals
 

Status: Recruiting

Condition Summary: Osteoporosis; Fragility Fractures

 

Last Updated: 6 Aug 2007

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Weekly vs Daily Teriparatide Therapy in Severe Postmenopausal Osteoporosis
 

Status: Recruiting

Condition Summary: Osteoporosis

 

Last Updated: 15 Apr 2014

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A Safety and Efficacy Study to Evaluate AMG 785 in South Korean Women With Osteoporosis.
 

Status: Not yet recruiting

Condition Summary: Postmenopausal Osteoporosis (PMO)

 

Last Updated: 26 Jul 2016

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