Osteoporosis

Common Name(s)

Osteoporosis

Osteoporosis is a condition that causes bones to become weak and brittle. Bone is living tissue that is constantly being broken down and replaced. When you are young, your body typically makes new bone faster than it breaks down old bone. This leads to dense bone mass (strong bones). When the creation of new bone is unable to keep up with the removal of old bone, they become weak and brittle. If osteoporosis is severe enough, a crack or break (fracture) within the bone can occur from something as minor as a fall or even from a normal action, like coughing. Symptoms of osteoporosis may include back pain, decrease in height, a hunched posture, and increased risk of bone fractures.

Most people reach their peak bone mass by their early 20s. Individuals with a high peak bone mass when they are young have a lower chance of developing osteoporosis as they age. Gender, age, and race are all risk factors for developing osteoporosis. Women, individuals who are white or of Asian descent, and the elderly have an increased risk of developing osteoporosis. Low calcium intake, eating disorders, and gastrointestinal surgery can also cause a greater risk for osteoporosis. Certain medications, especially steroids, as well as tobacco use, excessive alcohol consumption and a sedentary lifestyle all increase the risk for osteoporosis.

Specific types of X-ray images, called DXA scans, may be used to determine your bone density and diagnose osteoporosis. There are many forms of treatment, depending on the severity. It is important to talk to your doctor, if you or someone you know has been diagnosed with osteoporosis, to review the current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteoporosis" returned 2353 free, full-text research articles on human participants. First 3 results:

[Algal oligosaccharides ameliorate osteoporosis via up-regulation of parathyroid hormone 1-84 and vascular endothelial growth factor].
 

Author(s): Li Wang, Haiya Wang, Ningyuan Fang

Journal: J Tradit Chin Med. 2016 Jun;36(3):332-9.

 

To determine whether algal oligosac- charide~ affects the levels of parathyroid hormone 1-84 (PTH1-84) and vascular endothelial growth fac- tor (VEGF).

Last Updated: 29 Jul 2016

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Postmenopausal Osteoporosis.
 

Author(s): Karl Michaëlsson, Per Aspenberg

Journal: N. Engl. J. Med.. 2016 May;374(21):2095.

 

Last Updated: 26 May 2016

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Postmenopausal Osteoporosis.
 

Author(s): Dennis M Black, Clifford J Rosen

Journal: N. Engl. J. Med.. 2016 May;374(21):2096-7.

 

Last Updated: 26 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteoporosis" returned 653 free, full-text review articles on human participants. First 3 results:

Osteoporosis in Gastrointestinal Diseases.
 

Author(s): Iwona Krela-Kaźmierczak, Aleksandra Szymczak, Liliana Łykowska-Szuber, Piotr Eder, Krzysztof Linke

Journal: Adv Clin Exp Med. ;25(1):185-90.

 

Secondary osteoporosis occurs as an isolated pathology or co-exists with types I and II osteoporosis. The gastroenterologist may come across osteoporosis or osteopenia in a patient with a gastrointestinal disease. This is often a young patient in whom investigations should be carried ...

Last Updated: 3 Mar 2016

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Treatment of osteoporosis with eldecalcitol, a new vitamin D analog: a comprehensive review and meta-analysis of randomized clinical trials.
 

Author(s): Zhixing Xu, Changchun Fan, Xuechun Zhao, Hairong Tao

Journal:

 

Eldecalcitol (ELD) is an active form of vitamin D analog that has been approved for the treatment of osteoporosis in Japan. Over recent years, a number of multicenter, randomized controlled clinical trials have been conducted. Our goal is to comprehensively summarize the results from these studies.

Last Updated: 12 Feb 2016

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Acute bilateral uveitis and right macular edema induced by a single infusion of zoledronic acid for the treatment of postmenopausal osteoporosis as a substitution for oral alendronate: a case report.
 

Author(s): Yiming Tian, Rui Wang, Lianyuan Liu, Chunming Ma, Qiang Lu, Fuzai Yin

Journal:

 

Zoledronic acid-induced uveitis (ZAIU) is rare but severe, and has been recently considered part of an acute phase reaction. Only 15 cases have been reported since 2005. Here we describe a case with macular edema, which is the first reported case observed after long-term alendronate tolerance.

Last Updated: 12 Feb 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Jun 2016

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Multicenter Cohort Study on Osteoporosis
 

Status: Not yet recruiting

Condition Summary: Osteoporosis

 

Last Updated: 4 Nov 2016

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Multi-joint Coordination Underlies Upright Balance Control in Elderly With Osteoporosis
 

Status: Recruiting

Condition Summary: Osteoporosis

 

Last Updated: 7 Jul 2015

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