Osteoporosis

Common Name(s)

Osteoporosis

Osteoporosis is a condition that causes bones to become weak and brittle. Bone is living tissue that is constantly being broken down and replaced. When you are young, your body typically makes new bone faster than it breaks down old bone. This leads to dense bone mass (strong bones). When the creation of new bone is unable to keep up with the removal of old bone, they become weak and brittle. If osteoporosis is severe enough, a crack or break (fracture) within the bone can occur from something as minor as a fall or even from a normal action, like coughing. Symptoms of osteoporosis may include back pain, decrease in height, a hunched posture, and increased risk of bone fractures.

Most people reach their peak bone mass by their early 20s. Individuals with a high peak bone mass when they are young have a lower chance of developing osteoporosis as they age. Gender, age, and race are all risk factors for developing osteoporosis. Women, individuals who are white or of Asian descent, and the elderly have an increased risk of developing osteoporosis. Low calcium intake, eating disorders, and gastrointestinal surgery can also cause a greater risk for osteoporosis. Certain medications, especially steroids, as well as tobacco use, excessive alcohol consumption and a sedentary lifestyle all increase the risk for osteoporosis.

Specific types of X-ray images, called DXA scans, may be used to determine your bone density and diagnose osteoporosis. There are many forms of treatment, depending on the severity. It is important to talk to your doctor, if you or someone you know has been diagnosed with osteoporosis, to review the current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteoporosis" returned 2524 free, full-text research articles on human participants. First 3 results:

Male patients with rheumatoid arthritis have an increased risk of osteoporosis: Frequency and risk factors.
 

Author(s): Seong-Min Kweon, Dong Hyun Sohn, Ji-Heh Park, Jung Hee Koh, Eun-Kyoung Park, Han-Na Lee, Keunyoung Kim, Yunkyung Kim, Geun-Tae Kim, Seung-Geun Lee

Journal: Medicine (Baltimore). 2018 Jun;97(24):e11122.

 

Most previous research investigating osteoporosis in rheumatoid arthritis (RA) has focused on female patients and there is a lack of data regarding clinical characteristics of osteoporosis in male patients with RA.The aim of this study was to compare the frequency of osteoporosis ...

Last Updated: 31 Dec 1969

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Risk factors for osteoporosis in liver cirrhosis patients measured by transient elastography.
 

Author(s): Jian-Ping Zheng, Hai-Xiong Miao, Shao-Wei Zheng, Wei-le Liu, Chu-Qun Chen, Hao-Bo Zhong, Sheng-Fa Li, Yong-Ping Fang, Chun-Han Sun

Journal: Medicine (Baltimore). 2018 May;97(20):e10645.

 

Osteoporosis or osteopenia is a common complication in patients with cirrhosis, but little is known about the risk factors for the occurrence of osteoporosis.Patients with liver cirrhosis due to chronic virus infection and alcoholic abuse were enrolled. Bone mineral density (BMD) ...

Last Updated: 31 Dec 1969

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Osteoporosis and fracture after gastrectomy for stomach cancer: A nationwide claims study.
 

Author(s): Gi Hyeon Seo, Hae Yeon Kang, Eun Kyung Choe

Journal: Medicine (Baltimore). 2018 Apr;97(17):e0532.

 

This study was planned to evaluate the incidence and risk factors of osteoporosis and fracture after gastrectomy for stomach cancer using a nationwide claims database in South Korea.Data from 41,512 patients (50-79 years) who underwent gastrectomy for stomach cancer from 2008 to 2010 ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteoporosis" returned 700 free, full-text review articles on human participants. First 3 results:

THERAPY OF ENDOCRINE DISEASE: Denosumab vs bisphosphonates for the treatment of postmenopausal osteoporosis.
 

Author(s): Athanasios D Anastasilakis, Stergios A Polyzos, Polyzois Makras

Journal: Eur. J. Endocrinol.. 2018 Jul;179(1):R31-R45.

 

The most widely used medications for the treatment of osteoporosis are currently bisphosphonates (BPs) and denosumab (Dmab). Both are antiresorptives, thus targeting the osteoclast and inhibiting bone resorption. Dmab achieves greater suppression of bone turnover and greater increases ...

Last Updated: 31 Dec 1969

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Animal versus plant protein and adult bone health: A systematic review and meta-analysis from the National Osteoporosis Foundation.
 

Author(s): Marissa M Shams-White, Mei Chung, Zhuxuan Fu, Karl L Insogna, Micaela C Karlsen, Meryl S LeBoff, Sue A Shapses, Joachim Sackey, Jian Shi, Taylor C Wallace, Connie M Weaver

Journal:

 

Protein may have both beneficial and detrimental effects on bone health depending on a variety of factors, including protein source.

Last Updated: 31 Dec 1969

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Tuina for osteoporosis: A systematic review protocol.
 

Author(s): Youkang Dong, Rong Zhao, Chunlin Wang, Taipin Guo

Journal: Medicine (Baltimore). 2018 Feb;97(8):e9974.

 

Osteoporosis is one kind of commonly and frequently occurring global disease accompanying with serious complications. As a branch of the subject of Acupuncture-Tuina, tuina is widely applied for osteoporosis alone or combined with other methods in China and other nations while its ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 19 Apr 2018

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Jogging in the Change of Osteoporosis
 

Status: Not yet recruiting

Condition Summary: Osteoporosis

 

Last Updated: 29 Nov 2017

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Multicenter Cohort Study on Osteoporosis
 

Status: Recruiting

Condition Summary: Osteoporosis

 

Last Updated: 16 Apr 2018

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