Osteoporosis

Common Name(s)

Osteoporosis

Osteoporosis is a condition that causes bones to become weak and brittle. Bone is living tissue that is constantly being broken down and replaced. When you are young, your body typically makes new bone faster than it breaks down old bone. This leads to dense bone mass (strong bones). When the creation of new bone is unable to keep up with the removal of old bone, they become weak and brittle. If osteoporosis is severe enough, a crack or break (fracture) within the bone can occur from something as minor as a fall or even from a normal action, like coughing. Symptoms of osteoporosis may include back pain, decrease in height, a hunched posture, and increased risk of bone fractures.

Most people reach their peak bone mass by their early 20s. Individuals with a high peak bone mass when they are young have a lower chance of developing osteoporosis as they age. Gender, age, and race are all risk factors for developing osteoporosis. Women, individuals who are white or of Asian descent, and the elderly have an increased risk of developing osteoporosis. Low calcium intake, eating disorders, and gastrointestinal surgery can also cause a greater risk for osteoporosis. Certain medications, especially steroids, as well as tobacco use, excessive alcohol consumption and a sedentary lifestyle all increase the risk for osteoporosis.

Specific types of X-ray images, called DXA scans, may be used to determine your bone density and diagnose osteoporosis. There are many forms of treatment, depending on the severity. It is important to talk to your doctor, if you or someone you know has been diagnosed with osteoporosis, to review the current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteoporosis" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteoporosis" returned 2321 free, full-text research articles on human participants. First 3 results:

Association factor analysis between osteoporosis with cerebral artery disease: The STROBE study.
 

Author(s): Eun-Sun Jin, Je Hoon Jeong, Bora Lee, Soo Bin Im

Journal: Medicine (Baltimore). 2017 Mar;96(9):e6164.

 

The purpose of this study was to determine the clinical association factors between osteoporosis and cerebral artery disease in Korean population. Two hundred nineteen postmenopausal women and men undergoing cerebral computed tomography angiography were enrolled in this study to evaluate ...

Last Updated: 1 Mar 2017

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Beyond bone mineral density, FRAX-based tailor-made intervention thresholds for therapeutic decision in subjects on glucocorticoid: A nationwide osteoporosis survey.
 

Author(s): Shan-Fu Yu, Jia-Feng Chen, Yin-Chou Chen, Han-Ming Lai, Chi-Hua Ko, Wen-Chan Chiu, Fu-Mei Su, Chung-Yuan Hsu, Ben Yu-Jih Su, Chih-Hsing Wu, Tien-Tsai Cheng

Journal: Medicine (Baltimore). 2017 Feb;96(5):e5959.

 

Glucocorticoid-induced osteoporosis (GIOP) is the most common cause of secondary osteoporosis and confers a substantial risk for future fractures. Several recent guidelines for GIOP management have recommended the use of intervention thresholds to direct pharmacological therapy in ...

Last Updated: 2 Feb 2017

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Inflammation as a contributing factor among postmenopausal Saudi women with osteoporosis.
 

Author(s): Nasser M Al-Daghri, Ibrahim Aziz, Sobhy Yakout, Naji J Aljohani, Yousef Al-Saleh, Osama E Amer, Eman Sheshah, Ghaida Zakaria Younis, Fahad Badr M Al-Badr

Journal: Medicine (Baltimore). 2017 Jan;96(4):e5780.

 

Postmenopausal osteoporosis is an important metabolic bone disease characterized by rapid bone loss occurring in the postmenopausal period. Recently, the most prevalent form of clinically significant osteopenia and osteoporosis involves various inflammatory conditions. The aim of ...

Last Updated: 25 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteoporosis" returned 630 free, full-text review articles on human participants. First 3 results:

Qianggu capsule for the treatment of primary osteoporosis: evidence from a Chinese patent medicine.
 

Author(s): Xu Wei, Aili Xu, Hao Shen, Yanming Xie

Journal:

 

Qianggu Capsule, a Chinese patent medicine, has been widely applied in the clinical practice of primary osteoporosis (POP) in recent years. This study aims to summarize the effectiveness and safety of Qianggu Capsule in treating POP.

Last Updated: 14 Feb 2017

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New horizons in treatment of osteoporosis.
 

Author(s): Ozra Tabatabaei-Malazy, Pooneh Salari, Patricia Khashayar, Bagher Larijani

Journal:

 

Prevalence of osteoporosis is increasing both in developed and developing countries. Due to rapid growth in the burden and cost of osteoporosis, worldwide, it seems reasonable to focus on the reduction of fractures as the main goal of treatment. Although, efficient pharmacological ...

Last Updated: 8 Feb 2017

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Diagnosis and Management of Cirrhosis-Related Osteoporosis.
 

Author(s): LĂ­via Alves Amaral Santos, Fernando Gomes Romeiro

Journal: Biomed Res Int. 2016 ;2016():1423462.

 

Management of cirrhosis complications has greatly improved, increasing survival and quality of life of the patients. Despite that, some of these complications are still overlooked and scarcely treated, particularly those that are not related to the liver. This is the case of osteoporosis, ...

Last Updated: 14 Nov 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Jun 2016

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Multicenter Cohort Study on Osteoporosis
 

Status: Not yet recruiting

Condition Summary: Osteoporosis

 

Last Updated: 4 Nov 2016

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Study of Male Osteoporosis and Aging
 

Status: Recruiting

Condition Summary: Osteoporosis

 

Last Updated: 19 Apr 2007

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