Osteitis deformans

Common Name(s)

Osteitis deformans

Paget disease is a metabolic bone disease characterized by focal abnormalities of increased bone turnover affecting one or more sites throughout the skeleton, primarily the axial skeleton. Bone lesions in this disorder show evidence of increased osteoclastic bone resorption and disorganized bone structure. See reviews by {6:Ralston et al. (2008)} and {5:Ralston and Albagha (2014)}. For a discussion of genetic heterogeneity of Paget disease of bone, see {167250}.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Osteitis deformans" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Osteitis deformans" returned 11 free, full-text research articles on human participants. First 3 results:

Effect of Paget's disease of bone (osteitis deformans) on the progression of prostate cancer bone metastasis.
 

Author(s): S-M Tu, A Som, B Tu, C J Logothetis, M-H Lee, S-Cj Yeung

Journal: Br. J. Cancer. 2012 Aug;107(4):646-51.

 

Patients with prostate cancer tend to die from bone metastases. Until now, no evidence has shown that Paget's disease of bone (PDB) affects the progression of bone metastasis or overall survival of patients with prostate cancer.

Last Updated: 9 Aug 2012

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Control of osteitis deformans using glucagon, calcitonin, and mithramycin.
 

Author(s): J R Condon, J Surtees, V Robinson

Journal: Postgrad Med J. 1981 Feb;57(664):84-8.

 

Glucagon, porcine calcitonin, and mithramycin were given to patients with Paget's disease of bone. There was rapid complete relief of bone pain accompanied by biochemical improvement or normalization in all cases. Calcitonin and glucagon appear to have additive properties in Paget's ...

Last Updated: 29 Oct 1981

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Osteitis deformans (Paget's disease of bone) complicating hypoparathyroidism.
 

Author(s): G H Pitman, J E Rhoads

Journal: Ann. Surg.. 1969 Aug;170(2):286-91.

 

Last Updated: 5 Sep 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Osteitis deformans" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pathophysiology of Paget's Disease of Bone
 

Status: Recruiting

Condition Summary: Paget's Disease of Bone

 

Last Updated: 15 Jun 2016

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Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
 

Status: Recruiting

Condition Summary: Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia; Paget Disease of Bone; Frontotemporal Dementia; Myopathy

 

Last Updated: 12 May 2011

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Characterization of Familial Myopathy and Paget Disease of Bone
 

Status: Recruiting

Condition Summary: Muscle Disorder; Bone Disorder

 

Last Updated: 8 Feb 2017

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