Obesity

Common Name(s)

Obesity

Obesity is a condition characterized by the build up of excessive body fat. Obesity is defined differently depending on the country, but in Western countries, such as the U.S. and many European countries, obesity is defined as a body mass index (BMI) of 30 kg/m^2.

A BMI is calculated by taking a person's weight (in kilograms) and dividing it by the square of their height (in meters). Using the BMI, doctors may classify someone as underweight, normal weight, overweight, or obese. Obesity is further broken down into three categories. First, obesity I is measured as a BMI of 30-34.99 kg/m^2, obesity II is 35-39.99 kg/m^2, and obesity III is a BMI greater than 40 kg/m^2. It is important to note that these values are only recognized for adults (18+ years old). In adolescents, different scales are used based on a number of factors.

There are many potential causes for obesity such as environmental, genetic, or both. Contributing factors that may lead to obesity include a poor diet, little or no exercise, infections, and certain genetic conditions. Other contributing factors may include some social determinants such as socioeconomic class and geographic location. In any case, obesity can lead to serious health problems, including a lower life expectancy. On average, obesity can reduce an individual's life expectancy by six to seven years. Obesity may also lead to an increased risk for many conditions including type II diabetes, heart diseases, stroke, many cancers, gastrointestinal conditions, abnormal or poor breathing, depression, and more.

Generally, obesity is treated with certain lifestyle changes such as diet plans and making exercise routines. Medications and surgeries may also be an option depending on the cause of the obesity, its severity, and the individual's choices. If you or someone you know has been diagnosed with obesity, contact your doctor to discuss the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obesity" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

Last Updated: 14 Mar 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obesity" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

http://www.bardetbiedl.org/

Last Updated: 14 Mar 2013

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Obesity" returned 11445 free, full-text research articles on human participants. First 3 results:

Mechanisms, Pathophysiology, and Management of Obesity.
 

Author(s): Nai-wei Sheu, Yu-Chih Lin, Chung-Jen Chen

Journal: N. Engl. J. Med.. 2017 04;376(15):1490.

 

Last Updated: 13 Apr 2017

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The effects of Jiao-Tai-Wan on sleep, inflammation and insulin resistance in obesity-resistant rats with chronic partial sleep deprivation.
 

Author(s): Xin Zou, Wenya Huang, Fuer Lu, Ke Fang, Dingkun Wang, Shuyong Zhao, Jiming Jia, Lijun Xu, Kaifu Wang, Nan Wang, Hui Dong

Journal:

 

Jiao-Tai-Wan (JTW), composed of Rhizome Coptidis and Cortex Cinnamomi, is a classical traditional Chinese prescription for treating insomnia. Several in vivo studies have concluded that JTW could exert its therapeutical effect in insomnia rats. However, the specific mechanism is still ...

Last Updated: 24 Mar 2017

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Combined effect of obesity and uric acid on nonalcoholic fatty liver disease and hypertriglyceridemia.
 

Author(s): Shujun Zhang, Tingting Du, Mengni Li, Huiming Lu, Xuan Lin, Xuefeng Yu

Journal: Medicine (Baltimore). 2017 Mar;96(12):e6381.

 

Hyperuricemia is associated with metabolic syndrome (MetS), but the association is often confounded by the shared background of obesity. We sought to explore the modifying effects of obesity on the association between uric acid (UA), MetS components, and nonalcoholic fatty liver disease ...

Last Updated: 22 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Obesity" returned 2317 free, full-text review articles on human participants. First 3 results:

Gene-Diet Interaction and Precision Nutrition in Obesity.
 

Author(s): Yoriko Heianza, Lu Qi

Journal:

 

The rapid rise of obesity during the past decades has coincided with a profound shift of our living environment, including unhealthy dietary patterns, a sedentary lifestyle, and physical inactivity. Genetic predisposition to obesity may have interacted with such an obesogenic environment ...

Last Updated: 7 Apr 2017

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EJE PRIZE 2017: Hypothalamic AMPK: a golden target against obesity?
 

Author(s): Miguel López

Journal: Eur. J. Endocrinol.. 2017 May;176(5):R235-R246.

 

AMP-activated protein kinase (AMPK) is a cellular gauge that is activated under conditions, such as low energy, increasing energy production and reducing energy waste. Centrally, the AMPK pathway is a canonical route regulating energy homeostasis, by integrating peripheral signals, ...

Last Updated: 24 Feb 2017

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Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child.
 

Author(s): Patrick M Catalano, Kartik Shankar

Journal:

 

Obesity is the most common medical condition in women of reproductive age. Obesity during pregnancy has short term and long term adverse consequences for both mother and child. Obesity causes problems with infertility, and in early gestation it causes spontaneous pregnancy loss and ...

Last Updated: 9 Feb 2017

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Gastrointestinal Hormonal Regulation of Obesity
 

Status: Recruiting

Condition Summary: Obesity

 

Last Updated: 4 Jan 2017

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Mobile Health Obesity Wellness Intervention in Rural Older Adults - Home-Based Pilot
 

Status: Not yet recruiting

Condition Summary: Obesity

 

Last Updated: 3 Apr 2017

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Pleasure for Food and Endocannabinoids in Obesity
 

Status: Recruiting

Condition Summary: Obesity

 

Last Updated: 23 Feb 2016

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