Botulism

Common Name(s)

Botulism

Botulism is a disease caused by the bacteria Clostridium botulinum. There are three main types: infant botulism, foodbourne botulism, and wound botulism. All types are very serious and can be fatal. Each type of botulism has different symptoms, but all include muscle weakness, paralysis, and drooping of the eyes. For all cases, direct contact or ingestion of the bacteria causes the disease. There is an antitoxin available for early prevention of botulism that stops further harm by the infection. For foodborne infections, doctors may induce vomiting and bowel movements to force the bacteria out of your system.

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Condition Specific Organizations

Following organizations serve the condition "Botulism" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Botulism" returned 193 free, full-text research articles on human participants. First 3 results:

Cluster of two cases of botulism due to Clostridium baratii type F in France, November 2014.
 

Author(s): C Castor, C Mazuet, M Saint-Leger, S Vygen, J Coutureau, M Durand, M R Popoff, N Jourdan Da Silva

Journal:

 

The first two cases in France of botulism due to Clostridium baratii type F were identified in November 2014, in the same family. Both cases required prolonged respiratory assistance. One of the cases had extremely high toxin serum levels and remained paralysed for two weeks. Investigations ...

Last Updated: 20 Feb 2015

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Genetic characterization and comparison of Clostridium botulinum isolates from botulism cases in Japan between 2006 and 2011.
 

Author(s): Tsuyoshi Kenri, Tsuyoshi Sekizuka, Akihiko Yamamoto, Masaaki Iwaki, Takako Komiya, Takashi Hatakeyama, Hiroshi Nakajima, Motohide Takahashi, Makoto Kuroda, Keigo Shibayama

Journal: Appl. Environ. Microbiol.. 2014 Nov;80(22):6954-64.

 

Genetic characterization was performed for 10 group I Clostridium botulinum strains isolated from botulism cases in Japan between 2006 and 2011. Of these, 1 was type A, 2 were type B, and 7 were type A(B) {carrying a silent bont/B [bont/(B)] gene} serotype strains, based on botulinum ...

Last Updated: 18 Oct 2014

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[Two cases of food-borne botulism in patients over 75 years of age].
 

Author(s): P Garcia-Galvez, J Hernandez-Cristobal, R Sebastian-Cambon, J M Fernandez-Carril, C Marian-Crespo, C Gimeno-Fernandez

Journal: Rev Neurol. 2014 Sep;59(6):286-8.

 

Last Updated: 5 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Botulism" returned 14 free, full-text review articles on human participants. First 3 results:

Botulinum neurotoxins and botulism: a novel therapeutic approach.
 

Author(s): Jeeraphong Thanongsaksrikul, Wanpen Chaicumpa

Journal: Toxins (Basel). 2011 May;3(5):469-88.

 

Specific treatment is not available for human botulism. Current remedial mainstay is the passive administration of polyclonal antibody to botulinum neurotoxin (BoNT) derived from heterologous species (immunized animal or mouse hybridoma) together with supportive and symptomatic management. ...

Last Updated: 9 Nov 2011

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Food-borne botulism in Argentina.
 

Author(s): Victoria Rebagliati, Romina Philippi, Mariela Tornese, Analia Paiva, Laura Rossi, Alcides Troncoso

Journal:

 

Botulism is a severe neuroparalytic disease caused by Clostridium botulinum toxins. Although the disease is uncommon it is a cause of great concern due to its high rate of mortality. Food-borne outbreaks of botulism occur worldwide and require immediate public health attention and ...

Last Updated: 17 Sep 2009

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Infant botulism.
 

Author(s): Lucia Fenicia, Fabrizio Anniballi

Journal: Ann. Ist. Super. Sanita. 2009 ;45(2):134-46.

 

Infant botulism is a rare disease that affects infant less than 12 months of age. The illness results from absorption of botulinum toxin produced in situ by neurotoxigenic clostridia that can temporarily colonize the intestinal tract of infants. To date, all inhabited continents except ...

Last Updated: 28 Jul 2009

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.