Neuroblastoma 2

Common Name(s)

Neuroblastoma 2

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuroblastoma 2" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neuroblastoma 2" returned 118 free, full-text research articles on human participants. First 3 results:

TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.
 

Author(s): P L Chavali, R K R Saini, Q Zhai, D Vizlin-Hodzic, S Venkatabalasubramanian, A Hayashi, E Johansson, Z-j Zeng, S Mohlin, S PĂ„hlman, L Hansford, D R Kaplan, K Funa

Journal:

 

Nuclear orphan receptor TLX (Drosophila tailless homolog) is essential for the maintenance of neural stem/progenitor cell self-renewal, but its role in neuroblastoma (NB) is not well understood. Here, we show that TLX is essential for the formation of tumor spheres in three different ...

Last Updated: 31 Oct 2014

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MYCN-dependent expression of sulfatase-2 regulates neuroblastoma cell survival.
 

Author(s): Valeria Solari, Lucia Borriello, Gianluca Turcatel, Hiroyuki Shimada, Richard Sposto, G Esteban Fernandez, Shahab Asgharzadeh, Edwin A Yates, Jeremy E Turnbull, Yves A DeClerck

Journal: Cancer Res.. 2014 Nov;74(21):5999-6009.

 

Heparan sulfate proteoglycans (HSPG) play a critical role in the interaction of tumor cells and their microenvironment. HSPG activity is dictated by sulfation patterns controlled by sulfotransferases, which add sulfate groups, and sulfatases (Sulf), which remove 6-O-sulfates. Here, ...

Last Updated: 1 Nov 2014

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Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma.
 

Author(s): Mei-Hong Li, Miriam Harel, Timothy Hla, Fernando Ferrer

Journal: J. Pediatr. Surg.. 2014 Aug;49(8):1286-91.

 

Neuroblastoma (NB) is the most common extracranial solid tumor of childhood. Preliminary data derived from a human angiogenesis array in NB showed that the bioactive lipid sphingosine-1-phosphate (S1P) induced the secretion of several angiogenesis-related proteins including the important ...

Last Updated: 5 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neuroblastoma 2" returned 1 free, full-text review articles on human participants. First 3 results:

The development of antibody-IL-2 based immunotherapy with hu14.18-IL2 (EMD-273063) in melanoma and neuroblastoma.
 

Author(s): Brett H Yamane, Jacquelyn A Hank, Mark R Albertini, Paul M Sondel

Journal: Expert Opin Investig Drugs. 2009 Jul;18(7):991-1000.

 

Patients with high risk melanoma and neuroblastoma frequently experience recurrence despite surgical resection and appropriate adjuvant therapies. Immunotherapy with the immunocytokine hu14.18-IL2 (EMD-273063) was developed by means of fusion of two molecules of IL-2 to the monoclonal ...

Last Updated: 24 Jun 2009

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Activated T Cells Armed With GD2 Bispecific Antibody in Children and Young Adults With Neuroblastoma and Osteosarcoma
 

Status: Recruiting

Condition Summary: Desmoplastic Small Round Cell Tumor; Disseminated Neuroblastoma; Metastatic Childhood Soft Tissue Sarcoma; Metastatic Ewing Sarcoma/PNET; Metastatic Osteosarcoma; Recurrent Adult Soft Tissue Sarcoma; Recurrent Childhood Soft Tissue Sarcoma; Recurrent Ewing Sarcoma/PNET; Recurrent Melanoma; Recurrent Neuroblastoma; Recurrent Osteosarcoma

 

Last Updated: 25 Mar 2015

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Last Updated: 25 Jun 2015

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