Neuroblastoma 1

Common Name(s)

Neuroblastoma 1

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuroblastoma 1" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuroblastoma 1" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neuroblastoma 1" returned 161 free, full-text research articles on human participants. First 3 results:

Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma.
 

Author(s): Mei-Hong Li, Miriam Harel, Timothy Hla, Fernando Ferrer

Journal: J. Pediatr. Surg.. 2014 Aug;49(8):1286-91.

 

Neuroblastoma (NB) is the most common extracranial solid tumor of childhood. Preliminary data derived from a human angiogenesis array in NB showed that the bioactive lipid sphingosine-1-phosphate (S1P) induced the secretion of several angiogenesis-related proteins including the important ...

Last Updated: 5 Aug 2014

Go To URL
Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma.
 

Author(s): L Chen, Y Zhao, G C Halliday, P Berry, R F Rousseau, S A Middleton, G L Nichols, F Del Bello, A Piergentili, D R Newell, J Lunec, D A Tweddle

Journal: Br. J. Cancer. 2014 Aug;111(4):716-25.

 

A frequent mechanism of acquired multidrug resistance in human cancers is overexpression of ATP-binding cassette transporters such as the Multi-Drug Resistance Protein 1 (MDR-1). Nutlin-3, an MDM2-p53 antagonist, has previously been reported to be a competitive MDR-1 inhibitor.

Last Updated: 13 Aug 2014

Go To URL
Flotillin-1 regulates oncogenic signaling in neuroblastoma cells by regulating ALK membrane association.
 

Author(s): Arata Tomiyama, Takamasa Uekita, Reiko Kamata, Kazuki Sasaki, Junko Takita, Miki Ohira, Akira Nakagawara, Chifumi Kitanaka, Kentaro Mori, Hideki Yamaguchi, Ryuichi Sakai

Journal: Cancer Res.. 2014 Jul;74(14):3790-801.

 

Neuroblastomas harbor mutations in the nonreceptor anaplastic lymphoma kinase (ALK) in 8% to 9% of cases where they serve as oncogenic drivers. Strategies to reduce ALK activity offer clinical interest based on initial findings with ALK kinase inhibitors. In this study, we characterized ...

Last Updated: 16 Jul 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neuroblastoma 1" returned 0 free, full-text review articles on human participants.

 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 14 Aug 2015

Go to URL
Phase 1 Study of MM-398 Plus Cyclophosphamide in Pediatric Solid Tumors
 

Status: Recruiting

Condition Summary: Recurrent or Refractory Solid Tumors; Ewing Sarcoma; Rhabdomyosarcoma; Neuroblastoma; Osteosarcoma

 

Last Updated: 6 Apr 2015

Go to URL
WEE1 Inhibitor MK-1775 and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
 

Status: Recruiting

Condition Summary: Childhood Solid Neoplasm; Recurrent Childhood Medulloblastoma; Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor; Recurrent Neuroblastoma

 

Last Updated: 11 Aug 2015

Go to URL