MYH-associated polyposis

Common Name(s)

MYH-associated polyposis

MYH-associated polyposis is an inherited condition characterized by the development of multiple adenomatous colon polyps and an increased risk of colorectal cancer.  This condition, a milder form of familial adenomatous polyposis (FAP), is sometimes called autosomal recessive familial adenomatous polyposis because it is inherited in an autosomal recessive manner. People with this condition have fewer polyps than those with the classic type of FAP; fewer than 100 polyps typically develop, rather than hundreds or thousands. They may also be at increased risk for upper gastrointestinal polyps.  MYH-associated polyposis is caused by mutations in the MYH gene.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "MYH-associated polyposis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "MYH-associated polyposis" returned 7 free, full-text research articles on human participants. First 3 results:

Recurrent testicular germ cell tumors in a family with MYH-associated polyposis.
 

Author(s): Adela Castillejo, Ana Beatriz Sanchez-Heras, Rodrigo Jover, Maria Isabel Castillejo, Carla Guarinos, Silvestre Oltra, Ana Martínez-Canto, Victor Manuel Barbera, Juan Laforga, Artemio Paya, Cristina Alenda, Jose Luis Soto

Journal: J. Clin. Oncol.. 2012 Aug;30(23):e216-7.

 

Last Updated: 9 Aug 2012

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Map syndrome (MYH Associated Polyposis) colorectal cancer, etiopathological connections.
 

Author(s): A Bolocan, D Ion, R V Stoian, M B Serban

Journal: J Med Life. ;4(1):109-11.

 

The case presented raised our scientific curiosity and it is worthy of being brought in front of the medical audience because of several reasons presented below. Presently, there are 3 hereditary syndromes that have a demonstrated etiological relationship with the colorectal cancer: ...

Last Updated: 20 Apr 2011

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Pathological features of colorectal carcinomas in MYH-associated polyposis.
 

Author(s): A M O'Shea, S P Cleary, M A Croitoru, H Kim, T Berk, N Monga, R H Riddell, A Pollett, S Gallinger

Journal: Histopathology. 2008 Aug;53(2):184-94.

 

MYH is a DNA glycosylase in the base excision repair pathway. Germ-line biallelic mutations in the MYH gene are associated with the development of multiple colorectal adenomas and colorectal carcinoma (CRC). A slightly increased risk of CRC is suggested in monoallelic MYH mutation ...

Last Updated: 28 Aug 2008

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "MYH-associated polyposis" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Apr 2014

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Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
 

Status: Recruiting

Condition Summary: Familial Adenomatous Polyposis

 

Last Updated: 3 Aug 2011

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Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
 

Status: Recruiting

Condition Summary: Familial Adenomatous Polyposis

 

Last Updated: 7 Oct 2014

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