Multiple sclerosis susceptibility

Common Name(s)

Multiple sclerosis susceptibility

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Multiple sclerosis susceptibility" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Multiple sclerosis susceptibility" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Multiple sclerosis susceptibility" returned 101 free, full-text research articles on human participants. First 3 results:

Genetic Variants of SNCA Are Associated with Susceptibility to Parkinson's Disease but Not Amyotrophic Lateral Sclerosis or Multiple System Atrophy in a Chinese Population.
 

Author(s): YongPing Chen, Qian-Qian Wei, RuWei Ou, Bei Cao, XuePing Chen, Bi Zhao, XiaoYan Guo, Yuan Yang, Ke Chen, Ying Wu, Wei Song, Hui-Fang Shang

Journal:

 

The polymorphisms of α-synuclein (SNCA), rs3775444, rs3822086 and rs11931074 that are strongly associated with Parkinson's disease (PD) in Caucasian populations, were examined in this study to elucidate the role of polymorphisms in different ethnic backgrounds. The possible associations ...

Last Updated: 25 Jul 2015

Go To URL
Combinations of susceptibility genes are associated with higher risk for multiple sclerosis and imply disease course specificity.
 

Author(s): Denis A Akkad, Alexandra Olischewsky, Franziska Reiner, Kerstin Hellwig, Sarika Esser, Jörg T Epplen, Tomaz Curk, Ralf Gold, Aiden Haghikia

Journal:

 

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that predominantly affects young adults. The genetic contributions to this multifactorial disease were underscored by a genome wide association study (GWAS) conducted by the International Multiple ...

Last Updated: 27 May 2015

Go To URL
Detecting deoxyhemoglobin in spinal cord vasculature of the experimental autoimmune encephalomyelitis mouse model of multiple sclerosis using susceptibility MRI and hyperoxygenation.
 

Author(s): Nabeela Nathoo, James A Rogers, V Wee Yong, Jeff F Dunn

Journal:

 

Susceptibility-weighted imaging (SWI) detects hypointensities due to iron deposition and deoxyhemoglobin. Previously it was shown that SWI detects hypointensities in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS), most of which are due to intravascular ...

Last Updated: 21 May 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Multiple sclerosis susceptibility" returned 3 free, full-text review articles on human participants. First 3 results:

Modelling genetic susceptibility to multiple sclerosis with family data.
 

Author(s): Cullen O'Gorman, Rui Lin, James Stankovich, Simon A Broadley

Journal: Neuroepidemiology. 2013 ;40(1):1-12.

 

A genetic contribution to susceptibility is well established in multiple sclerosis (MS) and 57 associated genetic loci have been identified. We have undertaken a meta-analysis of familial risk studies with the aims of providing definitive figures for risks to relatives, performing ...

Last Updated: 21 Dec 2012

Go To URL
Sex-related factors in multiple sclerosis susceptibility and progression.
 

Author(s): Rhonda R Voskuhl, Stefan M Gold

Journal:

 

The pathogenesis of multiple sclerosis (MS) involves complex interactions between genetic susceptibility and environmental triggers. Clinical observations suggest that the study of sex differences might provide important insight into mechanisms of pathogenesis and progression of the ...

Last Updated: 7 May 2012

Go To URL
Role of HLA class II genes in susceptibility and resistance to multiple sclerosis: studies using HLA transgenic mice.
 

Author(s): David Luckey, Dikshya Bastakoty, Ashutosh K Mangalam

Journal: J. Autoimmun.. 2011 Sep;37(2):122-8.

 

Multiple sclerosis (MS), an inflammatory and demyelinating autoimmune disease of CNS has both, a genetic and an environmental predisposition. Among all the genetic factors associated with MS susceptibility, HLA class II haplotypes such as DR2/DQ6, DR3/DQ2, and DR4/DQ8 show the strongest ...

Last Updated: 14 Sep 2011

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility
 

Status: Recruiting

Condition Summary: Multiple Sclerosis

 

Last Updated: 11 May 2016

Go to URL
Genes and Environment in Multiple Sclerosis
 

Status: Recruiting

Condition Summary: Multiple Sclerosis

 

Last Updated: 26 Jan 2016

Go to URL