Multiple sclerosis susceptibility

Common Name(s)

Multiple sclerosis susceptibility

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Multiple sclerosis susceptibility" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Multiple sclerosis susceptibility" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Multiple sclerosis susceptibility" returned 106 free, full-text research articles on human participants. First 3 results:

Common and Low Frequency Variants in MERTK Are Independently Associated with Multiple Sclerosis Susceptibility with Discordant Association Dependent upon HLA-DRB1*15:01 Status.
 

Author(s): Michele D Binder, Andrew D Fox, Daniel Merlo, Laura J Johnson, Lauren Giuffrida, Sarah E Calvert, Rainer Akkermann, Gerry Z M Ma, , Ashwyn A Perera, Melissa M Gresle, Louise Laverick, Grace Foo, Marzena J Fabis-Pedrini, Timothy Spelman, Margaret A Jordan, Alan G Baxter, Simon Foote, Helmut Butzkueven, Trevor J Kilpatrick, Judith Field

Journal:

 

Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. The risk of developing MS is strongly influenced by genetic predisposition, and over 100 loci have been established as associated with susceptibility. However, the biologically relevant ...

Last Updated: 19 Mar 2016

Go To URL
Oral Contraceptives and Multiple Sclerosis/Clinically Isolated Syndrome Susceptibility.
 

Author(s): Kerstin Hellwig, Lie H Chen, Frank Z Stancyzk, Annette M Langer-Gould

Journal:

 

The incidence of multiple sclerosis (MS) is rising in women.

Last Updated: 8 Mar 2016

Go To URL
Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not Associated with Diseases Susceptibility.
 

Author(s): Hongyan An, Chai Lim, Gilles J Guillemin, Ute Vollmer-Conna, William Rawlinson, Katherine Bryant, Nicodemus Tedla

Journal:

 

Leukocyte immunoglobulin-like receptor A3 (LILRA3) is a soluble immune regulatory molecule primarily expressed by monocytes and macrophages. A homozygous 6.7kbp LILRA3 gene deletion that removes the first seven of its eight exons is predicted to lead to lack of LILRA3 protein, although ...

Last Updated: 13 Feb 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Multiple sclerosis susceptibility" returned 3 free, full-text review articles on human participants. First 3 results:

Modelling genetic susceptibility to multiple sclerosis with family data.
 

Author(s): Cullen O'Gorman, Rui Lin, James Stankovich, Simon A Broadley

Journal: Neuroepidemiology. 2013 ;40(1):1-12.

 

A genetic contribution to susceptibility is well established in multiple sclerosis (MS) and 57 associated genetic loci have been identified. We have undertaken a meta-analysis of familial risk studies with the aims of providing definitive figures for risks to relatives, performing ...

Last Updated: 21 Dec 2012

Go To URL
Sex-related factors in multiple sclerosis susceptibility and progression.
 

Author(s): Rhonda R Voskuhl, Stefan M Gold

Journal:

 

The pathogenesis of multiple sclerosis (MS) involves complex interactions between genetic susceptibility and environmental triggers. Clinical observations suggest that the study of sex differences might provide important insight into mechanisms of pathogenesis and progression of the ...

Last Updated: 7 May 2012

Go To URL
Role of HLA class II genes in susceptibility and resistance to multiple sclerosis: studies using HLA transgenic mice.
 

Author(s): David Luckey, Dikshya Bastakoty, Ashutosh K Mangalam

Journal: J. Autoimmun.. 2011 Sep;37(2):122-8.

 

Multiple sclerosis (MS), an inflammatory and demyelinating autoimmune disease of CNS has both, a genetic and an environmental predisposition. Among all the genetic factors associated with MS susceptibility, HLA class II haplotypes such as DR2/DQ6, DR3/DQ2, and DR4/DQ8 show the strongest ...

Last Updated: 14 Sep 2011

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility
 

Status: Recruiting

Condition Summary: Multiple Sclerosis

 

Last Updated: 31 Aug 2016

Go to URL
Genes and Environment in Multiple Sclerosis
 

Status: Recruiting

Condition Summary: Multiple Sclerosis

 

Last Updated: 26 Jan 2016

Go to URL