Multiple sclerosis susceptibility

Common Name(s)

Multiple sclerosis susceptibility

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Multiple sclerosis susceptibility" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Multiple sclerosis susceptibility" returned 86 free, full-text research articles on human participants. First 3 results:

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.
 

Author(s): Maureen D Mayes, Lara Bossini-Castillo, Olga Gorlova, José Ezequiel Martin, Xiaodong Zhou, Wei V Chen, Shervin Assassi, Jun Ying, Filemon K Tan, Frank C Arnett, John D Reveille, Sandra Guerra, María Teruel, Francisco David Carmona, Peter K Gregersen, Annette T Lee, Elena López-Isac, Eguzkine Ochoa, Patricia Carreira, Carmen Pilar Simeón, Iván Castellví, Miguel Ángel González-Gay, , Alexandra Zhernakova, Leonid Padyukov, Marta Alarcón-Riquelme, Cisca Wijmenga, Matthew Brown, Lorenzo Beretta, Gabriela Riemekasten, Torsten Witte, Nicolas Hunzelmann, Alexander Kreuter, Jörg H W Distler, Alexandre E Voskuyl, Annemie J Schuerwegh, Roger Hesselstrand, Annika Nordin, Paolo Airó, Claudio Lunardi, Paul Shiels, Jacob M van Laar, Ariane Herrick, Jane Worthington, Christopher Denton, Fredrick M Wigley, Laura K Hummers, John Varga, Monique E Hinchcliff, Murray Baron, Marie Hudson, Janet E Pope, Daniel E Furst, Dinesh Khanna, Kristin Phillips, Elena Schiopu, Barbara M Segal, Jerry A Molitor, Richard M Silver, Virginia D Steen, Robert W Simms, Robert A Lafyatis, Barri J Fessler, Tracy M Frech, Firas Alkassab, Peter Docherty, Elzbieta Kaminska, Nader Khalidi, Henry Niall Jones, Janet Markland, David Robinson, Jasper Broen, Timothy R D J Radstake, Carmen Fonseca, Bobby P Koeleman, Javier Martin

Journal: Am. J. Hum. Genet.. 2014 Jan;94(1):47-61.

 

In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human leukocyte antigen (HLA) region were imputed and tested. These analyses resulted in a model composed of ...

Last Updated: 6 Jan 2014

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Smoking and multiple sclerosis susceptibility.
 

Author(s): Anna Karin Hedström, Jan Hillert, Tomas Olsson, Lars Alfredsson

Journal: Eur. J. Epidemiol.. 2013 Nov;28(11):867-74.

 

Smoking is one of the most established risk factors for multiple sclerosis (MS). The aim of this study was to investigate how age at smoking debut, duration, intensity and cumulative dose of smoking, and smoking cessation influence the association between smoking and MS risk. In two ...

Last Updated: 2 Dec 2013

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Association of multiple sclerosis susceptibility variants and early attack location in the CNS.
 

Author(s): Ellen M Mowry, Robert F Carey, Maria R Blasco, Jean Pelletier, Pierre Duquette, Pablo Villoslada, Irina Malikova, Elaine Roger, R Phillip Kinkel, Jamie McDonald, Peter Bacchetti, Emmanuelle Waubant

Journal:

 

The anatomic location of subsequent relapses in early multiple sclerosis (MS) appears to be predicted by the first attack location. We sought to determine if genetic polymorphisms associated with MS susceptibility are associated with attack location.

Last Updated: 16 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Multiple sclerosis susceptibility" returned 2 free, full-text review articles on human participants. First 3 results:

Modelling genetic susceptibility to multiple sclerosis with family data.
 

Author(s): Cullen O'Gorman, Rui Lin, James Stankovich, Simon A Broadley

Journal: Neuroepidemiology. 2013 ;40(1):1-12.

 

A genetic contribution to susceptibility is well established in multiple sclerosis (MS) and 57 associated genetic loci have been identified. We have undertaken a meta-analysis of familial risk studies with the aims of providing definitive figures for risks to relatives, performing ...

Last Updated: 21 Dec 2012

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Role of HLA class II genes in susceptibility and resistance to multiple sclerosis: studies using HLA transgenic mice.
 

Author(s): David Luckey, Dikshya Bastakoty, Ashutosh K Mangalam

Journal: J. Autoimmun.. 2011 Sep;37(2):122-8.

 

Multiple sclerosis (MS), an inflammatory and demyelinating autoimmune disease of CNS has both, a genetic and an environmental predisposition. Among all the genetic factors associated with MS susceptibility, HLA class II haplotypes such as DR2/DQ6, DR3/DQ2, and DR4/DQ8 show the strongest ...

Last Updated: 14 Sep 2011

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility
 

Status: Recruiting

Condition Summary: Multiple Sclerosis

 

Last Updated: 11 Nov 2014

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Genes and Environment in Multiple Sclerosis
 

Status: Recruiting

Condition Summary: Multiple Sclerosis

 

Last Updated: 20 Feb 2013

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