Mitochondrial myopathy

Common Name(s)

Mitochondrial myopathy

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mitochondrial myopathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mitochondrial myopathy" returned 109 free, full-text research articles on human participants. First 3 results:

Adult-onset Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke (MELAS)-like Encephalopathy Diagnosed Based on the Complete Sequencing of Mitochondrial DNA Extracted from Biopsied Muscle without any Myopathic Changes.
 

Author(s): Masako Mukai, Eiichiro Nagata, Atsushi Mizuma, Mitsuhiko Yamano, Keizo Sugaya, Ichizo Nishino, Yu-Ichi Goto, Shunya Takizawa

Journal: Intern. Med.. ;56(1):95-99.

 

The clinical features of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) are not uniform. We herein report a male patient with unusual MELAS-like encephalopathy who had been experiencing isolated recurrent stroke-like episodes since he was ...

Last Updated: 4 Jan 2017

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Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia.
 

Author(s): Terence E Ryan, Cameron A Schmidt, Rick J Alleman, Alvin M Tsang, Thomas D Green, P Darrell Neufer, David A Brown, Joseph M McClung

Journal: J. Mol. Cell. Cardiol.. 2016 Aug;97():191-6.

 

Critical limb ischemia is a devastating manifestation of peripheral arterial disease with no effective strategies for improving morbidity and mortality outcomes. We tested the hypothesis that cellular mitochondrial function is a key component of limb pathology and that improving mitochondrial ...

Last Updated: 27 Aug 2016

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Early Onset of Diabetes Mellitus Accelerates Cognitive Decline in Japanese Patients with Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes.
 

Author(s): Takaaki Murakami, Yuya Shinoto, Shin Yonemitsu, Seiji Muro, Shogo Oki, Yasutoshi Koga, Yu-Ichi Goto, Daita Kaneda

Journal: Tohoku J. Exp. Med.. 2016 ;238(4):311-6.

 

Approximately 80% of patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) carry the A3243G mutation in the mitochondrial tRNALeu (UUR) gene. Conversely, this mutation has also been identified as one of the most prevalent genetic abnormalities ...

Last Updated: 11 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mitochondrial myopathy" returned 8 free, full-text review articles on human participants. First 3 results:

When should MELAS (Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes) be the diagnosis?
 

Author(s): Paulo José Lorenzoni, Lineu Cesar Werneck, Cláudia Suemi Kamoi Kay, Carlos Eduardo Soares Silvado, Rosana Herminia Scola

Journal: Arq Neuropsiquiatr. 2015 Nov;73(11):959-67.

 

Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) is a rare mitochondrial disorder. Diagnostic criteria for MELAS include typical manifestations of the disease: stroke-like episodes, encephalopathy, evidence of mitochondrial dysfunction (laboratorial ...

Last Updated: 31 Oct 2015

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Progress in Diagnosing Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episodes.
 

Author(s): Ying-Xin Wang, Wei-Dong Le

Journal: Chin. Med. J.. 2015 Jul;128(13):1820-5.

 

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is a progressive, multisystem affected mitochondrial disease associated with a number of disease-related defective genes. MELAS has unpredictable presentations and clinical course, and it can ...

Last Updated: 26 Jun 2015

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Scoliosis in mitochondrial myopathy: case report and review of the literature.
 

Author(s): Zheng Li, Jianxiong Shen, Jinqian Liang

Journal: Medicine (Baltimore). 2015 Feb;94(6):e513.

 

The mitochondrial myopathies include a diverse group of disorders characterized by morphological abnormalities of muscle mitochondria. Little is reported about spinal deformity associated with this syndrome.This study presents a case of scoliosis occurring in the setting of mitochondrial ...

Last Updated: 14 Feb 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

RTA 408 Capsules in Patients With Mitochondrial Myopathy - MOTOR
 

Status: Recruiting

Condition Summary: MItochondrial Myopathies

 

Last Updated: 14 Nov 2016

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A Study of Bezafibrate in Mitochondrial Myopathy
 

Status: Recruiting

Condition Summary: Mitochondrial Diseases

 

Last Updated: 29 Mar 2017

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Oxidative Capacity and Exercise Tolerance in Ambulatory SMA
 

Status: Recruiting

Condition Summary: Spinal Muscular Atrophy Type 3; Mitochondrial Myopathy

 

Last Updated: 16 Dec 2016

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