Mitochondrial myopathy

Common Name(s)

Mitochondrial myopathy

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mitochondrial myopathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mitochondrial myopathy" returned 99 free, full-text research articles on human participants. First 3 results:

Axial mitochondrial myopathy in a patient with rapidly progressive adult-onset scoliosis.
 

Author(s): Annie Hiniker, Lee-Jun Wong, Sigurd Berven, Cavatina K Truong, Adekunle M Adesina, Marta Margeta

Journal:

 

Axial myopathy can be the underlying cause of rapidly progressive adult-onset scoliosis; however, the pathogenesis of this disorder remains poorly understood. Here we present a case of a 69-year old woman with a family history of scoliosis affecting both her mother and her son, who ...

Last Updated: 23 Jan 2015

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Mitochondrial myopathy with dystrophic features due to a novel mutation in the MTTM gene.
 

Author(s): Lorenzo Peverelli, Carl A Gold, Ali B Naini, Kurenai Tanji, H Orhan Akman, Michio Hirano, Salvatore Dimauro

Journal: Muscle Nerve. 2014 Aug;50(2):292-5.

 

A 61-year-old woman with a 5-year history of progressive muscle weakness and atrophy had a muscle biopsy characterized by a combination of dystrophic features (necrotic fibers and endomysial fibrosis) and mitochondrial alterations [ragged-red, cytochrome c oxidase (COX)-negative fibers].

Last Updated: 22 Jul 2014

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The presence of multiple cellular defects associated with a novel G50E iron-sulfur cluster scaffold protein (ISCU) mutation leads to development of mitochondrial myopathy.
 

Author(s): Prasenjit Prasad Saha, S K Praveen Kumar, Shubhi Srivastava, Devanjan Sinha, Gautam Pareek, Patrick D'Silva

Journal: J. Biol. Chem.. 2014 Apr;289(15):10359-77.

 

Iron-sulfur (Fe-S) clusters are versatile cofactors involved in regulating multiple physiological activities, including energy generation through cellular respiration. Initially, the Fe-S clusters are assembled on a conserved scaffold protein, iron-sulfur cluster scaffold protein ...

Last Updated: 14 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mitochondrial myopathy" returned 5 free, full-text review articles on human participants. First 3 results:

Mitochondrial myopathy: a rare cause of early-onset vocal fold atrophy.
 

Author(s): Elizabeth A Kelly, Jonathan M Bock, Amanda C Peltier, Shin J Oh, C Gaelyn Garrett

Journal: Ann. Otol. Rhinol. Laryngol.. 2013 Mar;122(3):177-82.

 

We present the second published case of laryngeal involvement in mitochondrial myopathy.

Last Updated: 12 Apr 2013

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Respiratory complex III dysfunction in humans and the use of yeast as a model organism to study mitochondrial myopathy and associated diseases.
 

Author(s): B Meunier, N Fisher, S Ransac, J-P Mazat, G Brasseur

Journal: Biochim. Biophys. Acta. ;1827(11-12):1346-61.

 

The bc1 complex or complex III is a central component of the aerobic respiratory chain in prokaryotic and eukaryotic organisms. It catalyzes the oxidation of quinols and the reduction of cytochrome c, establishing a proton motive force used to synthesize adenosine triphosphate (ATP) ...

Last Updated: 23 Sep 2013

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Mechanisms of zidovudine-induced mitochondrial toxicity and myopathy.
 

Author(s): Erin R Scruggs, Amie J Dirks Naylor

Journal: Pharmacology. 2008 ;82(2):83-8.

 

Zidovudine (3-azido-3'-deoxythymidine), also referred to as azidothymidine (AZT), has become an integral component in highly active antiretroviral therapy, and has also been used in the treatment of cancer. The clinical effectiveness of AZT is constrained due to its association with ...

Last Updated: 18 Aug 2008

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 14 Apr 2015

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RTA 408 Capsules in Patients With Mitochondrial Myopathy - MOTOR
 

Status: Recruiting

Condition Summary: MItochondrial Myopathies

 

Last Updated: 20 Jul 2015

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The Effects of Exercise Versus Inactivity on People With Mitochondrial Muscle Disease
 

Status: Recruiting

Condition Summary: Mitochondrial Myopathy

 

Last Updated: 18 May 2009

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