Bone Cancer

Common Name(s)

Bone Cancer

Bone cancer is a common form of cancer characterized by abnormal cell growth in the skeletal system. Individuals with this disorder may grow harmful tumors in the bone that can spread to the rest of the body if not diagnosed and treated early. Bones are important for maintaining the structure of the body and work closely with muscles to provide various movements. Bone cancer can thus cause individuals to be less capable of performing important movements, like walking and running. Doctors are usually able to diagnose this defect early in the abnormal growth process, as the resulting symptoms are quickly apparent. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. For prevention purposes, bone specialists may suggest individuals eat a high-calcium diet, and exercise regularly. If an individual's cancer has progressed, doctors may suggest chemotherapy to combat cancer symptoms.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone Cancer" returned 1434 free, full-text research articles on human participants. First 3 results:

Enhanced MAF Oncogene Expression and Breast Cancer Bone Metastasis.
 

Author(s): Milica Pavlovic, Anna Arnal-Estapé, Federico Rojo, Anna Bellmunt, Maria Tarragona, Marc Guiu, Evarist Planet, Xabier Garcia-Albéniz, Mónica Morales, Jelena Urosevic, Sylwia Gawrzak, Ana Rovira, Aleix Prat, Lara Nonell, Ana Lluch, Joël Jean-Mairet, Robert Coleman, Joan Albanell, Roger R Gomis

Journal:

 

There are currently no biomarkers for early breast cancer patient populations at risk of bone metastasis. Identification of mediators of bone metastasis could be of clinical interest.

Last Updated: 17 Sep 2015

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An Attempt to Evaluate Selected Aspects of "Bone-Fat Axis" Function in Healthy Individuals and Patients With Pancreatic Cancer.
 

Author(s): Wojciech Blogowski, Katarzyna Dolegowska, Anna Deskur, Barbara Dolegowska, Teresa Starzyńska

Journal: Medicine (Baltimore). 2015 Aug;94(32):e1303.

 

Recently, much attention has been paid to a potential biochemical cross-talk between the metabolism of the adipose tissue (AT) and bone (marrow), termed "bone-fat axis." We hypothesized that selected substances, participating in this "dialog," are associated with body mass and peripheral ...

Last Updated: 13 Aug 2015

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Bisphosphonates, bone, and breast cancer recurrence.
 

Author(s): Adam Brufsky, Aju Mathew

Journal: Lancet. 2015 Oct;386(10001):1319-20.

 

Last Updated: 14 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone Cancer" returned 137 free, full-text review articles on human participants. First 3 results:

Radium-223 in Bone-Metastatic Prostate Cancer: Current Data and Future Prospects.
 

Author(s): Brian Lewis, Elie Chalhoub, Carla Chalouhy, Oliver Sartor

Journal: Oncology (Williston Park, N.Y.). 2015 Jul;29(7):483-8.

 

Ra-223 (radium-223) is an alpha particle-emitting radiopharmaceutical with targeted uptake in areas of osteoblastic lesions. The combination of targeted skeletal uptake, short tissue-penetration range, and high energy of alpha particles allows for targeted cell killing and a low toxicity ...

Last Updated: 16 Jul 2015

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Osteoprotegerin in breast cancer: beyond bone remodeling.
 

Author(s): Michael Weichhaus, Stephanie Tsang Mui Chung, Linda Connelly

Journal:

 

Osteoprotegerin (OPG) is a secreted protein and member of the Tumor Necrosis Factor (TNF) Receptor superfamily. OPG has been well characterized as a regulator of bone metabolism which acts by blocking osteoclast maturation and preventing bone breakdown. Given this role, early studies ...

Last Updated: 9 Jun 2015

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Role of bone-anabolic agents in the treatment of breast cancer bone metastases.
 

Author(s): Attaya Suvannasankha, John M Chirgwin

Journal: Breast Cancer Res.. 2014 ;16(6):484.

 

Skeletal metastases are an incurable complication afflicting the majority of patients who die from advanced breast cancer. They are most often osteolytic, characterized by net bone destruction and suppressed new bone formation. Life expectancy from first diagnosis of breast cancer ...

Last Updated: 7 May 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Sep 2012

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Study of Blood Samples From Patients With Osteosarcoma
 

Status: Recruiting

Condition Summary: Localized Osteosarcoma; Metastatic Osteosarcoma; Recurrent Osteosarcoma

 

Last Updated: 16 Nov 2015

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