Bone Cancer

Common Name(s)

Bone Cancer

Bone cancer is a common form of cancer characterized by abnormal cell growth in the skeletal system. Individuals with this disorder may grow harmful tumors in the bone that can spread to the rest of the body if not diagnosed and treated early. Bones are important for maintaining the structure of the body and work closely with muscles to provide various movements. Bone cancer can thus cause individuals to be less capable of performing important movements, like walking and running. Doctors are usually able to diagnose this defect early in the abnormal growth process, as the resulting symptoms are quickly apparent. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. For prevention purposes, bone specialists may suggest individuals eat a high-calcium diet, and exercise regularly. If an individual's cancer has progressed, doctors may suggest chemotherapy to combat cancer symptoms.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone Cancer" returned 1125 free, full-text research articles on human participants. First 3 results:

DLC1-dependent parathyroid hormone-like hormone inhibition suppresses breast cancer bone metastasis.
 

Author(s): Yufeng Wang, Rong Lei, Xueqian Zhuang, Ning Zhang, Hong Pan, Gang Li, Jing Hu, Xiaoqi Pan, Qian Tao, Da Fu, Jianru Xiao, Y Eugene Chin, Yibin Kang, Qifeng Yang, Guohong Hu

Journal: J. Clin. Invest.. 2014 Apr;124(4):1646-59.

 

Bone metastasis is a frequent complication of breast cancer that is often accelerated by TGF-β signaling; however, little is known about how the TGF-β pathway is regulated during bone metastasis. Here we report that deleted in liver cancer 1 (DLC1) is an important regulator of TGF-β ...

Last Updated: 2 Apr 2014

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Oral ibandronic acid versus intravenous zoledronic acid in treatment of bone metastases from breast cancer: a randomised, open label, non-inferiority phase 3 trial.
 

Author(s): Peter Barrett-Lee, Angela Casbard, Jacinta Abraham, Kerenza Hood, Robert Coleman, Peter Simmonds, Hayley Timmins, Duncan Wheatley, Robert Grieve, Gareth Griffiths, Nick Murray

Journal: Lancet Oncol.. 2014 Jan;15(1):114-22.

 

Bisphosphonates are routinely used in the treatment of metastatic bone disease from breast cancer to reduce pain and bone destruction. Zoledronic acid given by intravenous infusion has been widely used, but places a substantial logistical burden on both patient and hospital. As a ...

Last Updated: 3 Jan 2014

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Association between salivary α-amylase activity and pain relief scale scores in cancer patients with bone metastases treated with radiotherapy.
 

Author(s): Hong Liu, Wen-yan Dong, Jian-bo Wang, Tao Wang, Peng Hu, Shu-fang Wei, Lin Ye, Qing-wei Wang

Journal: Chin. Med. J.. 2013 Dec;126(23):4444-7.

 

Subjective assessment tools such as visual analog scales (VAS) or pain scores are commonly used to evaluate the intensity of chronic cancer-induced pain. However, their value is limited in some cases. We measured changes in VAS pain scores and salivary α-amylase (sAA) concentrations ...

Last Updated: 29 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone Cancer" returned 104 free, full-text review articles on human participants. First 3 results:

[Expert consensus on the diagnosis and treatment of bone metastasis in lung cancer (2014 version)].
 

Author(s): Yan Sun, Zhongzhen Guan, Meilin Liao, Xin Yu, Changli Wang, Jie Wang, Xiaohui Niu, Yuankai Shi, Xiuyi Zhi, Yunpeng Liu, Mengzhong Liu, Yiping Zhang, Yue Yang, Jingnan Shen, Gongyan Chen, Qinghua Zhou, Caicun Zhou, Qisen Guo, Lili Tang, Jianchun Duan, Jun Liang, Yingjian Zhang, Ying Cheng

Journal: Zhongguo Fei Ai Za Zhi. 2014 Feb;17(2):57-72.

 

Last Updated: 3 Mar 2014

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Targeted α-particle therapy of bone metastases in prostate cancer.
 

Author(s): Hossein Jadvar, David I Quinn

Journal: Clin Nucl Med. 2013 Dec;38(12):966-71.

 

Medical oncology is moving toward personalized and precision treatments. This evolution is spearheaded by ongoing discoveries on the fundamental machinery that controls tumor and hosts microenvironment biological behavior. α-Particles with their high energy and short range had long ...

Last Updated: 11 Nov 2013

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Regulation of breast cancer and bone metastasis by microRNAs.
 

Author(s): S Vimalraj, P J Miranda, B Ramyakrishna, N Selvamurugan

Journal: Dis. Markers. 2013 ;35(5):369-87.

 

Breast cancer progression including bone metastasis is a complex process involving numerous changes in gene expression and function. MicroRNAs (miRNAs) are small endogenous noncoding RNAs that regulate gene expression by targeting protein-coding mRNAs posttranscriptionally, often ...

Last Updated: 5 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Blood Samples From Patients With Osteosarcoma
 

Status: Recruiting

Condition Summary: Localized Osteosarcoma; Metastatic Osteosarcoma; Recurrent Osteosarcoma

 

Last Updated: 5 Aug 2014

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Last Updated: 11 Sep 2012

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