Bone Cancer

Common Name(s)

Bone Cancer

Bone cancer is a common form of cancer characterized by abnormal cell growth in the skeletal system. Individuals with this disorder may grow harmful tumors in the bone that can spread to the rest of the body if not diagnosed and treated early. Bones are important for maintaining the structure of the body and work closely with muscles to provide various movements. Bone cancer can thus cause individuals to be less capable of performing important movements, like walking and running. Doctors are usually able to diagnose this defect early in the abnormal growth process, as the resulting symptoms are quickly apparent. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. For prevention purposes, bone specialists may suggest individuals eat a high-calcium diet, and exercise regularly. If an individual's cancer has progressed, doctors may suggest chemotherapy to combat cancer symptoms.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone Cancer" returned 1470 free, full-text research articles on human participants. First 3 results:

CAPG and GIPC1: Breast Cancer Biomarkers for Bone Metastasis Development and Treatment.
 

Author(s): Jules A Westbrook, David A Cairns, Jianhe Peng, Valerie Speirs, Andrew M Hanby, Ingunn Holen, Steven L Wood, Penelope D Ottewell, Helen Marshall, Rozalind E Banks, Peter J Selby, Robert E Coleman, Janet E Brown

Journal:

 

Bone is the predominant site of metastasis from breast cancer, and recent trials have demonstrated that adjuvant bisphosphonate therapy can reduce bone metastasis development and improve survival. There is an unmet need for prognostic and predictive biomarkers so that therapy can ...

Last Updated: 13 Jan 2016

Go To URL
When Should ⁹⁹mTc Bone Scintigraphy Be Performed in cT1N0 Non-Small Cell Lung Cancer Patients?
 

Author(s): Hang Li, Hong Hu, Rui Wang, Yawei Zhang, Jiaqing Xiang, Quan Liu, Wei Shi, Yihua Sun, Haiquan Chen

Journal: Medicine (Baltimore). 2015 Dec;94(51):e2309.

 

The aim of this retrospective study was to investigate the risk factors for bone metastases (BM) in clinical T1N0 non-small cell lung cancer (NSCLC) patients.From January 2010 to June 2012, 739 patients with primary diagnosed cT1N0 NSCLC were eligible for this study. Clinical variables, ...

Last Updated: 25 Dec 2015

Go To URL
Enhanced MAF Oncogene Expression and Breast Cancer Bone Metastasis.
 

Author(s): Milica Pavlovic, Anna Arnal-Estapé, Federico Rojo, Anna Bellmunt, Maria Tarragona, Marc Guiu, Evarist Planet, Xabier Garcia-Albéniz, Mónica Morales, Jelena Urosevic, Sylwia Gawrzak, Ana Rovira, Aleix Prat, Lara Nonell, Ana Lluch, Joël Jean-Mairet, Robert Coleman, Joan Albanell, Roger R Gomis

Journal:

 

There are currently no biomarkers for early breast cancer patient populations at risk of bone metastasis. Identification of mediators of bone metastasis could be of clinical interest.

Last Updated: 17 Sep 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone Cancer" returned 143 free, full-text review articles on human participants. First 3 results:

Which metabolic imaging, besides bone scan with 99mTc-phosphonates, for detecting and evaluating bone metastases in prostatic cancer patients? An open discussion.
 

Author(s): E Bombardieri, L Setti, M Kirienko, L Antunovic, P Guglielmo, G Ciocia

Journal: Q J Nucl Med Mol Imaging. 2015 Dec;59(4):381-99.

 

Prostate cancer bone metastases occur frequently in advanced cancer and this is matter of particular attention, due to the great impact on patient's management and considering that a lot of new emerging therapeutic options have been recently introduced. Imaging bone metastases is ...

Last Updated: 29 Sep 2015

Go To URL
Radium-223 in Bone-Metastatic Prostate Cancer: Current Data and Future Prospects.
 

Author(s): Brian Lewis, Elie Chalhoub, Carla Chalouhy, Oliver Sartor

Journal: Oncology (Williston Park, N.Y.). 2015 Jul;29(7):483-8.

 

Ra-223 (radium-223) is an alpha particle-emitting radiopharmaceutical with targeted uptake in areas of osteoblastic lesions. The combination of targeted skeletal uptake, short tissue-penetration range, and high energy of alpha particles allows for targeted cell killing and a low toxicity ...

Last Updated: 16 Jul 2015

Go To URL
Osteoprotegerin in breast cancer: beyond bone remodeling.
 

Author(s): Michael Weichhaus, Stephanie Tsang Mui Chung, Linda Connelly

Journal:

 

Osteoprotegerin (OPG) is a secreted protein and member of the Tumor Necrosis Factor (TNF) Receptor superfamily. OPG has been well characterized as a regulator of bone metabolism which acts by blocking osteoclast maturation and preventing bone breakdown. Given this role, early studies ...

Last Updated: 9 Jun 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma
 

Status: Recruiting

Condition Summary: Childhood Osteosarcoma; Metastatic Osteosarcoma; Recurrent Osteosarcoma

 

Last Updated: 7 Jan 2016

Go to URL
Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung
 

Status: Recruiting

Condition Summary: Osteosarcoma; Metastatic Osteosarcoma

 

Last Updated: 5 Jan 2016

Go to URL