Bone Cancer

Common Name(s)

Bone Cancer

Bone cancer is a common form of cancer characterized by abnormal cell growth in the skeletal system. Individuals with this disorder may grow harmful tumors in the bone that can spread to the rest of the body if not diagnosed and treated early. Bones are important for maintaining the structure of the body and work closely with muscles to provide various movements. Bone cancer can thus cause individuals to be less capable of performing important movements, like walking and running. Doctors are usually able to diagnose this defect early in the abnormal growth process, as the resulting symptoms are quickly apparent. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. For prevention purposes, bone specialists may suggest individuals eat a high-calcium diet, and exercise regularly. If an individual's cancer has progressed, doctors may suggest chemotherapy to combat cancer symptoms.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone Cancer" returned 1085 free, full-text research articles on human participants. First 3 results:

Inaugural bone metastases in non-small cell lung cancer: a specific prognostic entity?
 

Author(s): Mélanie Deberne, Stanislas Ropert, Bertrand Billemont, Catherine Daniel, Jeanne Chapron, François Goldwasser

Journal:

 

In non-small cell lung cancer patients (NSCLC), median survival from the time patients develop bone metastasis is classically described being inferior to 6 months. We investigated the subcategory of patients having an inaugural skeletal-related-event revealing NSCLC. The purpose of ...

Last Updated: 16 Jun 2014

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Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer.
 

Author(s): Irene Zinonos, Ke-Wang Luo, Agatha Labrinidis, Vasilios Liapis, Shelley Hay, Vasilios Panagopoulos, Mark Denichilo, Chun-Hay Ko, Grace Gar-Lee Yue, Clara Bik-San Lau, Wendy Ingman, Vladimir Ponomarev, Gerald J Atkins, David M Findlay, Andrew C W Zannettino, Andreas Evdokiou

Journal: Int. J. Oncol.. 2014 Aug;45(2):532-40.

 

Osteoprotegerin (OPG) is a secreted member of the TNF receptor superfamily, which binds to the receptor activator of nuclear factor κB ligand (RANKL) and inhibits osteoclast activity and bone resorption. Systemic administration of recombinant OPG was previously shown to inhibit tumor ...

Last Updated: 10 Jun 2014

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Polymorphisms in the RANK/RANKL genes and their effect on bone specific prognosis in breast cancer patients.
 

Author(s): Alexander Hein, Christian M Bayer, Michael G Schrauder, Lothar Häberle, Katharina Heusinger, Reiner Strick, Matthias Ruebner, Michael P Lux, Stefan P Renner, Rüdiger Schulz-Wendtland, Arif B Ekici, Arndt Hartmann, Matthias W Beckmann, Peter A Fasching

Journal: Biomed Res Int. 2014 ;2014():842452.

 

The receptor activator of NF-κB (RANK) pathway is involved in bone health as well as breast cancer (BC) pathogenesis and progression. Whereas the therapeutic implication of this pathway is established for the treatment of osteoporosis and bone metastases, the application in adjuvant ...

Last Updated: 14 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone Cancer" returned 110 free, full-text review articles on human participants. First 3 results:

[Bone-targeted treatment in prostate cancer].
 

Author(s): Lajos Géczi, István Sinkovics

Journal: Magy Onkol. 2014 Sep;58(3):199-203.

 

Prostate cancer is one of the most common cancers in men. In case of metastatic disease, bone manifestation is presented in 85-90% of the patients. The new targeted treatments are the denosumab RANK-ligand monoclonal antibody and Ra-223-chloride radioisotope therapy. This paper summarizes ...

Last Updated: 27 Sep 2014

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Monitoring the response of bone metastases to treatment with Magnetic Resonance Imaging and nuclear medicine techniques: a review and position statement by the European Organisation for Research and Treatment of Cancer imaging group.
 

Author(s): F E Lecouvet, J N Talbot, C Messiou, P Bourguet, Y Liu, N M de Souza,

Journal: Eur. J. Cancer. 2014 Oct;50(15):2519-31.

 

Assessment of the response to treatment of metastases is crucial in daily oncological practice and clinical trials. For soft tissue metastases, this is done using computed tomography (CT), Magnetic Resonance Imaging (MRI) or Positron Emission Tomography (PET) using validated response ...

Last Updated: 26 Sep 2014

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Scoring systems of quantitative bone scanning in prostate cancer: historical overview, current status and future perspectives.
 

Author(s): Athanasios Zafeirakis

Journal: Hell J Nucl Med. ;17(2):136-44.

 

Whole-body bone scintigraphy using technetium-99m-methylene-diphosphonate ((99m)Tc-MDP) is the most widely used radionuclide imaging modality applied in patients with prostate cancer. With this technique, the choice of methods to estimate the extend of the metastatic disease on the ...

Last Updated: 6 Aug 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Sep 2012

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Study of Blood Samples From Patients With Osteosarcoma
 

Status: Recruiting

Condition Summary: Localized Osteosarcoma; Metastatic Osteosarcoma; Recurrent Osteosarcoma

 

Last Updated: 5 Aug 2014

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