Bone Cancer

Common Name(s)

Bone Cancer

Bone cancer is a common form of cancer characterized by abnormal cell growth in the skeletal system. Individuals with this disorder may grow harmful tumors in the bone that can spread to the rest of the body if not diagnosed and treated early. Bones are important for maintaining the structure of the body and work closely with muscles to provide various movements. Bone cancer can thus cause individuals to be less capable of performing important movements, like walking and running. Doctors are usually able to diagnose this defect early in the abnormal growth process, as the resulting symptoms are quickly apparent. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. For prevention purposes, bone specialists may suggest individuals eat a high-calcium diet, and exercise regularly. If an individual's cancer has progressed, doctors may suggest chemotherapy to combat cancer symptoms.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone Cancer" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bone Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bone Cancer" returned 1642 free, full-text research articles on human participants. First 3 results:

Outcomes of patients with bone metastases from differentiated thyroid cancer.
 

Author(s): Inés Califano, Susana Deutsch, Alicia Löwenstein, Carmen Cabezón, Fabián Pitoia

Journal: Arch Endocrinol Metab. 2018 Feb;62(1):14-20.

 

Objective Bone metastases (BM) from differentiated thyroid cancer (DTC) are associated with poor survival rates. Due to the low frequency of this entity, we performed a multicentric retrospective study that aimed to evaluate the presentation, outcome and causes of death in this population. ...

Last Updated: 31 Dec 1969

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Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor Activity.
 

Author(s): Annika Nordstrand, Erik Bovinder Ylitalo, Elin Thysell, Emma Jernberg, Sead Crnalic, Anders Widmark, Anders Bergh, Ulf H Lerner, Pernilla Wikström

Journal:

 

Advanced prostate cancer frequently metastasizes to bone and induces a mixed osteoblastic/osteolytic bone response. Standard treatment for metastatic prostate cancer is androgen-deprivation therapy (ADT) that also affects bone biology. Treatment options for patients relapsing after ...

Last Updated: 31 Dec 1969

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TGF- Overexpression in Breast Cancer Bone Metastasis and Primary Lesions and TGF- Enhancement of Expression of Procancer Metastasis Cytokines in Bone Marrow Mesenchymal Stem Cells.
 

Author(s): Jingbo Sun, Haiyan Cui, Yanxin Gao, Yangjian Pan, Kun Zhou, Jingzhan Huang, Jin Lan, Qingzhu Wei, Xiaolong Liu, Lixin Liu, Cory J Xian

Journal:

 

Bone metastasis (BM) is the advanced complication of breast cancer, while bone marrow-derived mesenchymal stem cells (BMSCs) in the microenvironment unclearly contribute to cancer metastasis. This study investigated potential roles of transforming growth factor- (TGF-) in the interaction ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bone Cancer" returned 188 free, full-text review articles on human participants. First 3 results:

Osteoclast inhibitors to prevent bone metastases in men with high-risk, non-metastatic prostate cancer: A systematic review and meta-analysis.
 

Author(s): Aimee R Hayes, Daniel Brungs, Nick Pavlakis

Journal:

 

In advanced prostate cancer, osteoclast inhibitors prevent and palliate skeletal related events associated with bone metastases. However, it is uncertain whether they play a disease-modifying role earlier in the course of the disease.

Last Updated: 31 Dec 1969

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Early identification and intervention matters: A comprehensive review of current evidence and recommendations for the monitoring of bone health in patients with cancer.
 

Author(s): Thomas Brodowicz, Peyman Hadji, Daniela Niepel, Ingo Diel

Journal: Cancer Treat. Rev.. 2017 Dec;61():23-34.

 

Bone metastases are common in patients with advanced solid tumors, and many individuals experience debilitating skeletal-related events (SREs; e.g. pathologic fracture, hypercalcemia, radiotherapy or surgery to bone, and spinal cord compression). These events substantially affect ...

Last Updated: 31 Dec 1969

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Endothelial Cells as Precursors for Osteoblasts in the Metastatic Prostate Cancer Bone.
 

Author(s): Ana E Paiva, Luiza Lousado, Viviani M Almeida, Julia P Andreotti, Gabryella S P Santos, Patrick O Azevedo, Isadora F G Sena, Pedro H D M Prazeres, Isabella T Borges, Vasco Azevedo, Akiva Mintz, Alexander Birbrair

Journal: Neoplasia. 2017 Nov;19(11):928-931.

 

Prostate cancer cells metastasize to the bones, causing ectopic bone formation, which results in fractures and pain. The cellular mechanisms underlying new bone production are unknown. In a recent study, Lin and colleagues, by using state-of-the-art techniques, including prostate ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Osteosarcoma Biobank in Peking University People's Hospital
 

Status: Not yet recruiting

Condition Summary: Osteosarcoma

 

Last Updated: 2 Dec 2017

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Biology of Osteosarcoma (BOOST) Registry and Biobank
 

Status: Recruiting

Condition Summary: Osteosarcoma

 

Last Updated: 21 Jul 2017

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A Phase II Trial of Avelumab in Patients With Recurrent or Progressive Osteosarcoma
 

Status: Recruiting

Condition Summary: Osteosarcoma

 

Last Updated: 20 Jun 2018

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