Meconium ileus

Common Name(s)

Meconium ileus

Meconium ileus refers to intestinal obstruction due to inspissated meconium in the distal ileum and cecum, which develops in utero and presents shortly after birth as a failure to pass meconium (summary by {1:Romi et al., 2012}). Meconium ileus is a known clinical manifestation of cystic fibrosis (CF; {219700}), and meconium ileus in the absence of CF is a rare phenomenon (summary by {2:Tal et al., 1985}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Meconium ileus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Meconium ileus" returned 31 free, full-text research articles on human participants. First 3 results:

[Congenital chloride diarrhea mimicking meconium ileus in newborn].
 

Author(s): Grażyna Krzemień, Agnieszka Szmigielska, Katarzyna Jankowska, Maria Roszkowska-Blaim

Journal: Med Wieku Rozwoj. ;17(4):320-3.

 

Congenital chloride diarrhoea is a rare autosomal recessive disease and the diagnosis is frequently delayed. The disease is most common in Saudi Arabia and Kuwait 1:3200-13 000 births, Finland - 1:30 000-40 000, and in Poland - 1:200 000. Congenital chloride diarrhoea begins in fetal ...

Last Updated: 12 Feb 2014

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Lethal course of meconium ileus in preterm twins revealing a novel cystic fibrosis mutation (p.Cys524Tyr).
 

Author(s): Alexander Puzik, Deborah J Morris-Rosendahl, Klaus-Dieter Rückauer, Claudia Otto, Peter Gessler, Ulrich Saueressig, Roland Hentschel

Journal:

 

In term newborns meconium ileus is frequently associated with cystic fibrosis. Reports on meconium ileus in preterm infants being diagnosed with cystic fibrosis early after birth are very scarce. Associations between genotype and phenotype in cystic fibrosis and its particular comorbidities ...

Last Updated: 22 Jan 2014

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Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.
 

Author(s): David A Stoltz, Tatiana Rokhlina, Sarah E Ernst, Alejandro A Pezzulo, Lynda S Ostedgaard, Philip H Karp, Melissa S Samuel, Leah R Reznikov, Michael V Rector, Nicholas D Gansemer, Drake C Bouzek, Mahmoud H Abou Alaiwa, Mark J Hoegger, Paula S Ludwig, Peter J Taft, Tanner J Wallen, Christine Wohlford-Lenane, James D McMenimen, Jeng-Haur Chen, Katrina L Bogan, Ryan J Adam, Emma E Hornick, George A Nelson, Eric A Hoffman, Eugene H Chang, Joseph Zabner, Paul B McCray, Randall S Prather, David K Meyerholz, Michael J Welsh

Journal: J. Clin. Invest.. 2013 Jun;123(6):2685-93.

 

Cystic fibrosis (CF) pigs develop disease with features remarkably similar to those in people with CF, including exocrine pancreatic destruction, focal biliary cirrhosis, micro-gallbladder, vas deferens loss, airway disease, and meconium ileus. Whereas meconium ileus occurs in 15% ...

Last Updated: 31 May 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Meconium ileus" returned 1 free, full-text review articles on human participants. First 3 results:

Intestinal obstruction syndromes in cystic fibrosis: meconium ileus, distal intestinal obstruction syndrome, and constipation.
 

Author(s): Hubert P J van der Doef, Freddy T M Kokke, Cornelis K van der Ent, Roderick H J Houwen

Journal: Curr Gastroenterol Rep. 2011 Jun;13(3):265-70.

 

Meconium ileus at birth, distal intestinal obstruction syndrome (DIOS), and constipation are an interrelated group of intestinal obstruction syndromes with a variable severity of obstruction that occurs in cystic fibrosis patients. Long-term follow-up studies show that today meconium ...

Last Updated: 3 May 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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