Lipoprotein glomerulopathy

Common Name(s)

Lipoprotein glomerulopathy

Lipoprotein glomerulopathy is an uncommon kidney disease characterized by proteinuria, progressive kidney failure, and distinctive lipoprotein thrombi in glomerular capillaries ({5:Saito et al., 2006}). It mainly affects people of Japanese and Chinese origin; in these populations, it is associated with mutations in the gene that encodes apolipoprotein E (APOE; {107741}). The disorder had rarely been described in Caucasians.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lipoprotein glomerulopathy" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lipoprotein glomerulopathy" returned 22 free, full-text research articles on human participants. First 3 results:

A case of lipoprotein glomerulopathy with thrombotic microangiopathy due to malignant hypertension.
 

Author(s): Yu Wu, Xiaohan Chen, Yuan Yang, Baohe Wang, Xiaoxia Liu, Ye Tao, Ping Fu, Zhangxue Hu

Journal:

 

Lipoprotein glomerulopathy (LPG) is a rare inherited renal disease characterized by intraglomerular lipoprotein within the lumina of severely dilated glomerular capillaries. The common clinical presentation of LPG includes proteinuria or nephrotic syndrome. Hypertension and anemia ...

Last Updated: 18 Mar 2013

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Thermodynamic and structural destabilization of apoE3 by hereditary mutations associated with the development of lipoprotein glomerulopathy.
 

Author(s): Dimitra Georgiadou, Kostas Stamatakis, Eleni K Efthimiadou, George Kordas, Donald Gantz, Angeliki Chroni, Efstratios Stratikos

Journal: J. Lipid Res.. 2013 Jan;54(1):164-76.

 

Lipoprotein glomerulopathy (LPG) is a dominant inherited kidney disorder characterized by lipoprotein thrombi in glomerular capillaries. Single-amino-acid mutations in apoE have been associated with the development of the disease, although the mechanism is unknown. In an effort to ...

Last Updated: 17 Dec 2012

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Significance of a novel apolipoprotein E variant, ApoE Osaka/Kurashiki, in lipoprotein glomerulopathy.
 

Author(s): Takao Saito, Akira Matsunaga

Journal: J. Atheroscler. Thromb.. 2011 ;18(6):542-3.

 

Last Updated: 29 Jun 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lipoprotein glomerulopathy" returned 2 free, full-text review articles on human participants. First 3 results:

[A case of lipoprotein glomerulopathy and a literature review of the subject].
 

Author(s): Hua Hu, Xinmin Zhang

Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 Mar;37(3):320-4.

 

To improve the understanding of lipoprotein glomerulopathy, the clinical data of a single case of lipoprotein glomerulopathy, diagnosed at the Second Xiangya Hospital, Central South University in June 2011, were retrospectively analyzed. The analysis included clinical manifestation, ...

Last Updated: 7 May 2012

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Lipoprotein glomerulopathy: a new role for apolipoprotein E?
 

Author(s): F E Karet, R P Lifton

Journal: J. Am. Soc. Nephrol.. 1997 May;8(5):840-2.

 

Last Updated: 12 Aug 1997

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Symptoms, Diagnosis, and Treatment

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