Ischemic stroke

Common Name(s)

Ischemic stroke

A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. It is said to be the third leading cause of death in the United States. {15:Gunel and Lifton (1996)} noted that about 20% of strokes are hemorrhagic, resulting in bleeding into the brain. Ischemic strokes, resulting from vascular occlusion, account for the majority of strokes. {4:Bersano et al. (2008)} reviewed genetic polymorphisms that have been implicated in the development of stroke. Candidate genes include those involved in hemostasis (see, e.g., F5; {612309}), the renin-angiotensin-aldosterone system (see, e.g., ACE; {106180}), homocysteine (see, e.g., MTHFR; {607093}), and lipoprotein metabolism (see, e.g., APOE; {107741}). See also hemorrhagic stroke, or intracerebral hemorrhage (ICH; {614519}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

Logo
National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

View Details

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ischemic stroke" returned 2795 free, full-text research articles on human participants. First 3 results:

Endovascular therapy for ischemic stroke.
 

Author(s): Bruce C V Campbell, Peter J Mitchell,

Journal: N. Engl. J. Med.. 2015 Jun;372(24):2365-6.

 

Last Updated: 11 Jun 2015

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CTP-Based Tissue Outcome: Promising Tool to Prove the Beneficial Effect of Mechanical Recanalization in Acute Ischemic Stroke.
 

Author(s): F Drewer-Gutland, A Kemmling, S Ligges, M Ritter, R Dziewas, E B Ringelstein, T U Niederstadt, W Heindel, V Heßelmann

Journal: Rofo. 2015 Jun;187(6):459-66.

 

To prove the tissue-protecting effect of mechanical recanalization, we assessed the CT perfusion-based tissue outcome ("TO") and correlated this imaging parameter with the 3-month clinical outcome ("CO").

Last Updated: 28 May 2015

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Association between left atrial appendage morphology evaluated by trans-esophageal echocardiography and ischemic cerebral stroke in patients with atrial fibrillation.
 

Author(s): Sherif A Sakr, Wagdia A El-Rasheedy, Mahmoud M Ramadan, Ibrahim El-Menshawy, Essam Mahfouz, Mohamed Bayoumi

Journal: Int Heart J. 2015 May;56(3):329-34.

 

The left atrial appendage (LAA) represents one of the major sources of cardiac thrombi responsible for embolic stroke in patients with atrial fibrillation (AF). The aim of the present study was to evaluate LAA structure and functions by transesophageal echocardiography (TEE) in patients ...

Last Updated: 14 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ischemic stroke" returned 347 free, full-text review articles on human participants. First 3 results:

Imaging-based management of acute ischemic stroke patients: current neuroradiological perspectives.
 

Author(s): Dong Gyu Na, Chul-Ho Sohn, Eung Yeop Kim

Journal: Korean J Radiol. ;16(2):372-90.

 

Advances in imaging-based management of acute ischemic stroke now provide crucial information such as infarct core, ischemic penumbra/degree of collaterals, vessel occlusion, and thrombus that helps in the selection of the best candidates for reperfusion therapy. It also predicts ...

Last Updated: 5 Mar 2015

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Endovascular intervention for acute ischemic stroke in light of recent trials.
 

Author(s): Kenan Alkhalili, Nohra Chalouhi, Stavropoula Tjoumakaris, David Hasan, Robert M Starke, Mario Zanaty, Robert H Rosenwasser, Pascal Jabbour

Journal: ScientificWorldJournal. 2014 ;2014():429549.

 

Three recently published trials, MR RESCUE, IMS III, and SYNTHESIS Expansion, evaluating the efficacy and safety of endovascular treatment of acute ischemic stroke have generated concerns about the future of endovascular approach. However, the tremendous evolution that imaging and ...

Last Updated: 22 Dec 2014

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Complications of the endovascular management of acute ischemic stroke.
 

Author(s): Heather L Gill, Jeffrey J Siracuse, In-Kyong Parrack, Zhen S Huang, Andrew J Meltzer

Journal:

 

Acute ischemic stroke is a significant source of morbidity and mortality across the globe. Currently, the only US Food and Drug Administration approved medical treatment of acute ischemic stroke is intravascular (IV) alteplase. While IV thrombolysis has been shown to decrease morbidity ...

Last Updated: 16 Dec 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke
 

Status: Recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 13 Apr 2015

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Last Updated: 8 Apr 2015

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Tongxinluo Capsule in Ischemic Stroke Patients(TISS)
 

Status: Not yet recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 7 Aug 2013

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