Ischemic stroke

Common Name(s)

Ischemic stroke

A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. It is said to be the third leading cause of death in the United States. {15:Gunel and Lifton (1996)} noted that about 20% of strokes are hemorrhagic, resulting in bleeding into the brain. Ischemic strokes, resulting from vascular occlusion, account for the majority of strokes. {4:Bersano et al. (2008)} reviewed genetic polymorphisms that have been implicated in the development of stroke. Candidate genes include those involved in hemostasis (see, e.g., F5; {612309}), the renin-angiotensin-aldosterone system (see, e.g., ACE; {106180}), homocysteine (see, e.g., MTHFR; {607093}), and lipoprotein metabolism (see, e.g., APOE; {107741}). See also hemorrhagic stroke, or intracerebral hemorrhage (ICH; {614519}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

Logo
National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

View Details

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ischemic stroke" returned 2556 free, full-text research articles on human participants. First 3 results:

Immediate recovery of an "ischemic stroke" following treatment with intravenous thiamine (vitamin B1).
 

Author(s): Arnon Blum, Michal Ovadia, Gil Rosen, Claudia Simsolo

Journal: Isr. Med. Assoc. J.. 2014 Aug;16(8):518-9.

 

Last Updated: 1 Oct 2014

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Endovascular treatment of acute ischemic stroke: an Indian experience from a tertiary care center.
 

Author(s): Vikram Huded, Rithesh R Nair, Romnesh de Souza, Devashish D Vyas

Journal: Neurol India. ;62(3):276-9.

 

In India, late presentation due to poor awareness about stroke precludes intravenous thrombolysis (IVT). Endovascular therapy can be used in these circumstances. We present our experience of endovascular treatment of acute ischemic stroke in a tertiary care center.

Last Updated: 18 Jul 2014

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Endovascular treatment in acute ischemic stroke: where it stands?
 

Author(s): J M K Murthy

Journal: Neurol India. ;62(3):237-8.

 

Last Updated: 18 Jul 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ischemic stroke" returned 300 free, full-text review articles on human participants. First 3 results:

Medium- and long-term efficacy of ligustrazine plus conventional medication on ischemic stroke: a systematic review and meta-analysis.
 

Author(s): Xiaojia Ni, Xiaojia Ni, Shaonan Liu, Xinfeng Guo

Journal: J Tradit Chin Med. 2013 Dec;33(6):715-20.

 

To evaluate the medium- to long-term efficacy of ligustrazine plus conventional medicine treating ischemic stroke.

Last Updated: 25 Mar 2014

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Current perspectives on the use of intravenous recombinant tissue plasminogen activator (tPA) for treatment of acute ischemic stroke.
 

Author(s): Sherita N Chapman, Prachi Mehndiratta, Michelle C Johansen, Timothy L McMurry, Karen C Johnston, Andrew M Southerland

Journal:

 

In 1995, the NINDS (National Institute of Neurological Disorders and Stroke) tPA (tissue plasminogen activator) Stroke Study Group published the results of a large multicenter clinical trial demonstrating efficacy of intravenous tPA by revealing a 30% relative risk reduction (absolute ...

Last Updated: 4 Mar 2014

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Acute supratentorial ischemic stroke: when surgery is mandatory.
 

Author(s): Gabriele Ronchetti, Pier Paolo Panciani, Roberto Stefini, Giannantonio Spena, Marco Maria Fontanella

Journal: Biomed Res Int. 2014 ;2014():624126.

 

Acute occlusion of middle cerebral artery (MCA) leads to severe brain swelling and to a malignant, often fatal syndrome. The authors summarize the current knowledge about such a condition and review the main surgical issues involved. Decompressive hemicraniectomy keeps being a valid ...

Last Updated: 14 Feb 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

DLBS1033 for Acute Ischemic Stroke Patients
 

Status: Not yet recruiting

Condition Summary: Ischemic Stroke; Partial Anterior Circulation Infarction; Lacunar Infarction by Bamford Criteria

 

Last Updated: 7 May 2014

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Tongxinluo Capsule in Ischemic Stroke Patients(TISS)
 

Status: Not yet recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 7 Aug 2013

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Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke
 

Status: Recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 2 Sep 2014

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