Ischemic stroke

Common Name(s)

Ischemic stroke

A stroke occurs when the blood flow to the brain is interrupted or cut-off. When this happens, the affected area of the brain does not receive the oxygen and nutrients that it needs. An ischemic stroke is the most common type of stroke and is caused by a blockage in an artery leading to the brain. A blocked artery will cut-off blood supply to a region of the brain. If the blood supply is blocked for more than a few minutes, brain cells will begin to die.

The two types of ischemic strokes are thrombotic and embolic. These terms refer to the location of the blood clot. In a thrombotic stroke, a blood clot forms in one of the blood vessels in the brain. In an embolic stroke, a blood clot forms elsewhere in the body, such as in the heart, and then travels to the brain to cause a blockage.

Ischemic strokes have many potential causes. Excessive blood cholesterol will cause the arteries to narrow and eventually become blocked—resulting in a thrombotic stroke. Blood clots that form in the heart are another cause of ischemic strokes. This occurs when blood clot forms in the heart and then travels to the head, blocking blood supply to the brain. This type of stroke would be an embolic stroke. Blood clots in the heart are more likely to form in people who have irregular heartbeats, have had a heart attack, or have diseased heart valves. Other causes of ischemic strokes include street drug use, traumatic injury to the blood vessels of the neck, and blood clotting disorders.

The risk for stroke is higher in older adults, women, and individuals of African heritage. Other risk factors include high blood pressure, heart disease, smoking, or diabetes. Emergency personnel should be called immediately if you think that you or someone around you is experiencing a stroke. There are a number of complications that can occur after a stroke. Support groups are a great resource for more information and resources.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

Logo
National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ischemic stroke" returned 3646 free, full-text research articles on human participants. First 3 results:

Correlation between Calpain-10 single-nucleotide polymorphisms and obstructive sleep apnea/hypopnoea syndrome with ischemic stroke in a Chinese population: A population-based study.
 

Author(s): Wei Zhang, Zhi-Ru Zhao, Chang-Fei Dai, Rong Zhang, Jie Chen, Hui-Juan Tian, Yun-Long Wang, Ji-Hong Sun, Qiu-Fang Lian

Journal: Medicine (Baltimore). 2017 Apr;96(16):e6570.

 

Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common chronic disorder which is followed by various complications. Calpain-10 belongs to a commonly expressed member of the Calpain-like cysteine protease family, which acts as risk marker for some diseases. The purpose of this ...

Last Updated: 19 Apr 2017

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Post-ischemic stroke rehabilitation is associated with a higher risk of fractures in older women: A population-based cohort study.
 

Author(s): Huei Kai Huang, Shu Man Lin, Clement Shih Hsien Yang, Chung Chao Liang, Hung Yu Cheng

Journal:

 

Rehabilitation can improve physical activity after stroke. However, patients may be more prone to falls and fractures because of balance and gait deficits. Few reports have studied the relationship between rehabilitation and subsequent fractures after ischemic stroke.

Last Updated: 17 Apr 2017

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Effect of Prior Atorvastatin Treatment on the Frequency of Hospital Acquired Pneumonia and Evolution of Biomarkers in Patients with Acute Ischemic Stroke: A Multicenter Prospective Study.
 

Author(s): Yuetian Yu, Cheng Zhu, Chunyan Liu, Yuan Gao

Journal: Biomed Res Int. 2017 ;2017():5642704.

 

Objective. To investigate whether prior treatment of atorvastatin reduces the frequency of hospital acquired pneumonia (HAP). Methods. Totally, 492 patients with acute ischemic stroke and Glasgow Coma Scale ≤ 8 were enrolled in this study. Subjects were assigned to prior atorvastatin ...

Last Updated: 30 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ischemic stroke" returned 469 free, full-text review articles on human participants. First 3 results:

Vectorized nanodelivery systems for ischemic stroke: a concept and a need.
 

Author(s): Andrés Da Silva-Candal, Bárbara Argibay, Ramón Iglesias-Rey, Zulema Vargas, Alba Vieites-Prado, Esteban López-Arias, Emilio Rodríguez-Castro, Iria López-Dequidt, Manuel Rodríguez-Yáñez, Yolanda Piñeiro, Tomás Sobrino, Francisco Campos, José Rivas, José Castillo

Journal:

 

Neurological diseases of diverse aetiologies have significant effects on the quality of life of patients. The limited self-repairing capacity of the brain is considered to be the origin of the irreversible and progressive nature of many neurological diseases. Therefore, neuroprotection ...

Last Updated: 12 Apr 2017

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The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury.
 

Author(s): Jianming Xiang, Lisa J Routhe, D Andrew Wilkinson, Ya Hua, Torben Moos, Guohua Xi, Richard F Keep

Journal:

 

While the impact of hemorrhagic and ischemic strokes on the blood-brain barrier has been extensively studied, the impact of these types of stroke on the choroid plexus, site of the blood-CSF barrier, has received much less attention. The purpose of this review is to examine evidence ...

Last Updated: 29 Mar 2017

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Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research.
 

Author(s): Cesar Reis, Onat Akyol, Wing Mann Ho, Camila Araujo, Lei Huang, Richard Applegate, John H Zhang

Journal: Biomed Res Int. 2017 ;2017():4863079.

 

Acute ischemic stroke is a devastating cause of death and disability, consequences of which depend on the time from ischemia onset to treatment, the affected brain region, and its size. The main targets of ischemic stroke therapy aim to restore tissue perfusion in the ischemic penumbra ...

Last Updated: 13 Mar 2017

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 19 Apr 2016

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Measuring Collaterals With Multi-phase CT Angiography in Patients With Ischemic Stroke
 

Status: Recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 10 May 2016

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