Ischemic stroke

Common Name(s)

Ischemic stroke

A stroke occurs when the blood flow to the brain is interrupted or cut-off. When this happens, the affected area of the brain does not receive the oxygen and nutrients that it needs. An ischemic stroke is the most common type of stroke and is caused by a blockage in an artery leading to the brain. A blocked artery will cut-off blood supply to a region of the brain. If the blood supply is blocked for more than a few minutes, brain cells will begin to die.

The two types of ischemic strokes are thrombotic and embolic. These terms refer to the location of the blood clot. In a thrombotic stroke, a blood clot forms in one of the blood vessels in the brain. In an embolic stroke, a blood clot forms elsewhere in the body, such as in the heart, and then travels to the brain to cause a blockage.

Ischemic strokes have many potential causes. Excessive blood cholesterol will cause the arteries to narrow and eventually become blocked—resulting in a thrombotic stroke. Blood clots that form in the heart are another cause of ischemic strokes. This occurs when blood clot forms in the heart and then travels to the head, blocking blood supply to the brain. This type of stroke would be an embolic stroke. Blood clots in the heart are more likely to form in people who have irregular heartbeats, have had a heart attack, or have diseased heart valves. Other causes of ischemic strokes include street drug use, traumatic injury to the blood vessels of the neck, and blood clotting disorders.

The risk for stroke is higher in older adults, women, and individuals of African heritage. Other risk factors include high blood pressure, heart disease, smoking, or diabetes. Emergency personnel should be called immediately if you think that you or someone around you is experiencing a stroke. There are a number of complications that can occur after a stroke. Support groups are a great resource for more information and resources.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

Logo
National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ischemic stroke" returned 3732 free, full-text research articles on human participants. First 3 results:

Long-term morbidity and mortality in patients without early complications after stroke or transient ischemic attack.
 

Author(s): Jodi D Edwards, Moira K Kapral, Jiming Fang, Richard H Swartz

Journal: CMAJ. 2017 Jul;189(29):E954-E961.

 

Secondary prevention after stroke and transient ischemic attack (TIA) has focused on high early risk of recurrence, but survivors of stroke can have substantial long-term morbidity and mortality. We quantified long-term morbidity and mortality for patients who had no early complications ...

Last Updated: 25 Jul 2017

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Effects of Smoking on Ischemic Stroke, Intracranial Hemorrhage, and Coronary Artery Events in Japanese Patients With Non-Valvular Atrial Fibrillation.
 

Author(s): Shinya Suzuki, Takayuki Otsuka, Koichi Sagara, Hiroaki Semba, Hiroto Kano, Shunsuke Matsuno, Hideaki Takai, Yuko Kato, Tokuhisa Uejima, Yuji Oikawa, Kazuyuki Nagashima, Hajime Kirigaya, Junji Yajima, Takashi Kunihara, Hitoshi Sawada, Tadanori Aizawa, Takeshi Yamashita

Journal: Int Heart J. 2017 Aug;58(4):506-515.

 

The effects of smoking on the prognosis of non-valvular atrial fibrillation (NVAF) patients are unclear.The Shinken Database 2004-11 (n = 17,517) includes all new patients visiting the Cardiovascular Institute between June 2004 and March 2012. Among these cases, 2,102 NVAF patients ...

Last Updated: 13 Jul 2017

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Cross-level interaction between individual socioeconomic status and regional deprivation on overall survival after onset of ischemic stroke: National health insurance cohort sample data from 2002 to 2013.
 

Author(s): Jaeyong Shin, Young Choi, Seung Woo Kim, Sang Gyu Lee, Eun-Cheol Park

Journal: J Epidemiol. 2017 Aug;27(8):381-388.

 

The literature on stroke mortality and neighborhood effect is characterized by studies that are often Western society-oriented, with a lack of racial and cultural diversity. We estimated the effect of cross-level interaction between individual and regional socioeconomic status on ...

Last Updated: 9 Jul 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ischemic stroke" returned 463 free, full-text review articles on human participants. First 3 results:

Efficacy and safety of desmoteplase in acute ischemic stroke patients: A systematic review and meta-analysis.
 

Author(s): Xiaoqiang Li, Li Ling, Chuqiao Li, Qiujie Ma

Journal: Medicine (Baltimore). 2017 May;96(18):e6667.

 

Pending results from double-blind, multicenter, parallel-group, randomized trials, the benefit and safety of the novel plasminogen activator, desmoteplase remain undetermined. The aim of this meta-analysis was to help evaluate desmoteplase's efficacy and safety.

Last Updated: 4 May 2017

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Vectorized nanodelivery systems for ischemic stroke: a concept and a need.
 

Author(s): Andrés Da Silva-Candal, Bárbara Argibay, Ramón Iglesias-Rey, Zulema Vargas, Alba Vieites-Prado, Esteban López-Arias, Emilio Rodríguez-Castro, Iria López-Dequidt, Manuel Rodríguez-Yáñez, Yolanda Piñeiro, Tomás Sobrino, Francisco Campos, José Rivas, José Castillo

Journal:

 

Neurological diseases of diverse aetiologies have significant effects on the quality of life of patients. The limited self-repairing capacity of the brain is considered to be the origin of the irreversible and progressive nature of many neurological diseases. Therefore, neuroprotection ...

Last Updated: 12 Apr 2017

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The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury.
 

Author(s): Jianming Xiang, Lisa J Routhe, D Andrew Wilkinson, Ya Hua, Torben Moos, Guohua Xi, Richard F Keep

Journal:

 

While the impact of hemorrhagic and ischemic strokes on the blood-brain barrier has been extensively studied, the impact of these types of stroke on the choroid plexus, site of the blood-CSF barrier, has received much less attention. The purpose of this review is to examine evidence ...

Last Updated: 29 Mar 2017

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 17 Jun 2017

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Measuring Collaterals With Multi-phase CT Angiography in Patients With Ischemic Stroke
 

Status: Recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 10 May 2016

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