Ischemic stroke

Common Name(s)

Ischemic stroke

A stroke occurs when the blood flow to the brain is interrupted or cut-off. When this happens, the affected area of the brain does not receive the oxygen and nutrients that it needs. An ischemic stroke is the most common type of stroke and is caused by a blockage in an artery leading to the brain. A blocked artery will cut-off blood supply to a region of the brain. If the blood supply is blocked for more than a few minutes, brain cells will begin to die.

The two types of ischemic strokes are thrombotic and embolic. These terms refer to the location of the blood clot. In a thrombotic stroke, a blood clot forms in one of the blood vessels in the brain. In an embolic stroke, a blood clot forms elsewhere in the body, such as in the heart, and then travels to the brain to cause a blockage.

Ischemic strokes have many potential causes. Excessive blood cholesterol will cause the arteries to narrow and eventually become blocked—resulting in a thrombotic stroke. Blood clots that form in the heart are another cause of ischemic strokes. This occurs when blood clot forms in the heart and then travels to the head, blocking blood supply to the brain. This type of stroke would be an embolic stroke. Blood clots in the heart are more likely to form in people who have irregular heartbeats, have had a heart attack, or have diseased heart valves. Other causes of ischemic strokes include street drug use, traumatic injury to the blood vessels of the neck, and blood clotting disorders.

The risk for stroke is higher in older adults, women, and individuals of African heritage. Other risk factors include high blood pressure, heart disease, smoking, or diabetes. Emergency personnel should be called immediately if you think that you or someone around you is experiencing a stroke. There are a number of complications that can occur after a stroke. Support groups are a great resource for more information and resources.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

Logo
National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ischemic stroke" returned 3276 free, full-text research articles on human participants. First 3 results:

Pioglitazone after Ischemic Stroke or Transient Ischemic Attack.
 

Author(s): Walter N Kernan, Catherine M Viscoli, Karen L Furie, Lawrence H Young, Silvio E Inzucchi, Mark Gorman, Peter D Guarino, Anne M Lovejoy, Peter N Peduzzi, Robin Conwit, Lawrence M Brass, Gregory G Schwartz, Harold P Adams, Leo Berger, Antonio Carolei, Wayne Clark, Bruce Coull, Gary A Ford, Dawn Kleindorfer, John R O'Leary, Mark W Parsons, Peter Ringleb, Souvik Sen, J David Spence, David Tanne, David Wang, Toni R Winder,

Journal: N. Engl. J. Med.. 2016 Apr;374(14):1321-31.

 

Patients with ischemic stroke or transient ischemic attack (TIA) are at increased risk for future cardiovascular events despite current preventive therapies. The identification of insulin resistance as a risk factor for stroke and myocardial infarction raised the possibility that ...

Last Updated: 7 Apr 2016

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Malposition of an atrial pacemaker lead crossing through patent foramen ovale in a patient with ischemic stroke.
 

Author(s): Yusuf Karavelioğlu, Tolga Doğan, Macit Kalçık, Adnan Yalçınkaya

Journal: Turk Kardiyol Dern Ars. 2016 Jan;44(1):87.

 

Last Updated: 15 Feb 2016

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Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: Prospective Validation of the HeRS Score.
 

Author(s): Elisabeth B Marsh, Rafael H Llinas, Andrea L C Schneider, Argye E Hillis, Erin Lawrence, Peter Dziedzic, Rebecca F Gottesman

Journal: Medicine (Baltimore). 2016 Jan;95(2):e2430.

 

Hemorrhagic transformation (HT) increases the morbidity and mortality of ischemic stroke. Anticoagulation is often indicated in patients with atrial fibrillation, low ejection fraction, or mechanical valves who are hospitalized with acute stroke, but increases the risk of HT. Risk ...

Last Updated: 15 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ischemic stroke" returned 412 free, full-text review articles on human participants. First 3 results:

Association between selected gene polymorphisms and statin metabolism, risk of ischemic stroke and cardiovascular disorders.
 

Author(s): Dariusz Kotlęga, Monika Gołąb-Janowska, Marta Masztalewicz, Sylwester Ciećwież, Przemysław Nowacki

Journal:

 

Statins are increasingly widely used in primary and secondary prevention of cardiovascular disorders, including ischemic stroke. The initial studies regarded mainly coronary heart disease, but recently more attention has been paid to statin use in ischemic stroke, including primary ...

Last Updated: 16 May 2016

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Paediatric arterial ischemic stroke: acute management, recent advances and remaining issues.
 

Author(s): Margherita Rosa, Silvana De Lucia, Victoria Elisa Rinaldi, Julie Le Gal, Marie Desmarest, Claudio Veropalumbo, Silvia Romanello, Luigi Titomanlio

Journal:

 

Stroke is a rare disease in childhood with an estimated incidence of 1-6/100.000. It has an increasingly recognised impact on child mortality along with its outcomes and effects on quality of life of patients and their families. Clinical presentation and risk factors of paediatric ...

Last Updated: 3 Dec 2015

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Interventional Ischemic Stroke Treatment--A (R)evolution.
 

Author(s): B Friedrich, M Gawlitza, J Fahnert, U Quäschling, T Kahn, D Lobsien, K-T Hoffmann

Journal: Rofo. 2016 Mar;188(3):259-67.

 

In recent years ischemic stroke caused by an intracranial vessel occlusion has become a treatable disease. Over decades intravenous thrombolysis by recombinant tissue plasminogen activator was the only accepted causal treatment of ischemic stroke supported by the results of randomized, ...

Last Updated: 24 Feb 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tongxinluo Capsule in Ischemic Stroke Patients(TISS)
 

Status: Not yet recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 7 Aug 2013

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Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke
 

Status: Recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 20 Jun 2016

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Last Updated: 17 Dec 2015

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