Ischemic stroke

Common Name(s)

Ischemic stroke

A stroke occurs when the blood flow to the brain is interrupted or cut-off. When this happens, the affected area of the brain does not receive the oxygen and nutrients that it needs. An ischemic stroke is the most common type of stroke and is caused by a blockage in an artery leading to the brain. A blocked artery will cut-off blood supply to a region of the brain. If the blood supply is blocked for more than a few minutes, brain cells will begin to die.

The two types of ischemic strokes are thrombotic and embolic. These terms refer to the location of the blood clot. In a thrombotic stroke, a blood clot forms in one of the blood vessels in the brain. In an embolic stroke, a blood clot forms elsewhere in the body, such as in the heart, and then travels to the brain to cause a blockage.

Ischemic strokes have many potential causes. Excessive blood cholesterol will cause the arteries to narrow and eventually become blocked—resulting in a thrombotic stroke. Blood clots that form in the heart are another cause of ischemic strokes. This occurs when blood clot forms in the heart and then travels to the head, blocking blood supply to the brain. This type of stroke would be an embolic stroke. Blood clots in the heart are more likely to form in people who have irregular heartbeats, have had a heart attack, or have diseased heart valves. Other causes of ischemic strokes include street drug use, traumatic injury to the blood vessels of the neck, and blood clotting disorders.

The risk for stroke is higher in older adults, women, and individuals of African heritage. Other risk factors include high blood pressure, heart disease, smoking, or diabetes. Emergency personnel should be called immediately if you think that you or someone around you is experiencing a stroke. There are a number of complications that can occur after a stroke. Support groups are a great resource for more information and resources.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

Logo
National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ischemic stroke" returned 3889 free, full-text research articles on human participants. First 3 results:

Could infarct location predict the long-term functional outcome in childhood arterial ischemic stroke?
 

Author(s): Mauricio López-Espejo, Marta Hernández-Chávez

Journal: Arq Neuropsiquiatr. 2017 Oct;75(10):692-696.

 

To explore the influence of infarct location on long-term functional outcome following a first-ever arterial ischemic stroke (AIS) in non-neonate children.

Last Updated: 31 Dec 1969

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The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model.
 

Author(s): Chul-Woong Woo, Jae-Im Kwon, Kyung-Won Kim, Jeong-Kon Kim, Sang-Beom Jeon, Seung-Chae Jung, Choong-Gon Choi, Sang-Tae Kim, Jinil Kim, Su Jeong Ham, Woo-Hyun Shim, Yu Sub Sung, Hyun Kwon Ha, Yoonseok Choi, Dong-Cheol Woo

Journal:

 

Emerging evidence has suggested that hydrogen sulfide (H2S) may alleviate the cellular damage associated with cerebral ischemia/reperfusion (I/R) injury. In this study, we assessed using 1H-magnetic resonance imaging/magnetic resonance spectroscopy (1H-MRI/MRS) and histologic analysis ...

Last Updated: 31 Dec 1969

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Functional polymorphism rs3783553 in the 3'-untranslated region of IL-1A increased the risk of ischemic stroke: A case-control study.
 

Author(s): Peng Wang, Qian He, Chen Liu, Shi Zhen He, Shou Yan Zhu, Ying Wen Li, Wei Su, Shu Tian Xiang, Bo Zhao

Journal: Medicine (Baltimore). 2017 Nov;96(46):e8522.

 

Accumulating evidence indicates interleukin-1 (IL-1) is a critical mediator of inflammatory responses in ischemic stroke (IS). The aim of this study was to investigate whether rs3783553 in the 3'-untranslated region of IL-1A was associated with the risk of IS. In this hospital-based ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ischemic stroke" returned 500 free, full-text review articles on human participants. First 3 results:

Comparative accuracy of CT perfusion in diagnosing acute ischemic stroke: A systematic review of 27 trials.
 

Author(s): Jiantong Shen, Xianglian Li, Youping Li, Bing Wu

Journal:

 

To systematically evaluate and compare the diagnostic accuracy of CT perfusion (CTP), non-enhanced computed tomography (NCCT) and computed tomography angiography (CTA) in detecting acute ischemic stroke.

Last Updated: 31 Dec 1969

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Efficacy and safety of desmoteplase in acute ischemic stroke patients: A systematic review and meta-analysis.
 

Author(s): Xiaoqiang Li, Li Ling, Chuqiao Li, Qiujie Ma

Journal: Medicine (Baltimore). 2017 May;96(18):e6667.

 

Pending results from double-blind, multicenter, parallel-group, randomized trials, the benefit and safety of the novel plasminogen activator, desmoteplase remain undetermined. The aim of this meta-analysis was to help evaluate desmoteplase's efficacy and safety.

Last Updated: 31 Dec 1969

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Vectorized nanodelivery systems for ischemic stroke: a concept and a need.
 

Author(s): Andrés Da Silva-Candal, Bárbara Argibay, Ramón Iglesias-Rey, Zulema Vargas, Alba Vieites-Prado, Esteban López-Arias, Emilio Rodríguez-Castro, Iria López-Dequidt, Manuel Rodríguez-Yáñez, Yolanda Piñeiro, Tomás Sobrino, Francisco Campos, José Rivas, José Castillo

Journal:

 

Neurological diseases of diverse aetiologies have significant effects on the quality of life of patients. The limited self-repairing capacity of the brain is considered to be the origin of the irreversible and progressive nature of many neurological diseases. Therefore, neuroprotection ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Nov 2017

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Predictors and Prognostic Factors on the Acute Ischemic Stroke
 

Status: Not yet recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 16 Apr 2017

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