Ischemic stroke

Common Name(s)

Ischemic stroke

A stroke occurs when the blood flow to the brain is interrupted or cut-off. When this happens, the affected area of the brain does not receive the oxygen and nutrients that it needs. An ischemic stroke is the most common type of stroke and is caused by a blockage in an artery leading to the brain. A blocked artery will cut-off blood supply to a region of the brain. If the blood supply is blocked for more than a few minutes, brain cells will begin to die.

The two types of ischemic strokes are thrombotic and embolic. These terms refer to the location of the blood clot. In a thrombotic stroke, a blood clot forms in one of the blood vessels in the brain. In an embolic stroke, a blood clot forms elsewhere in the body, such as in the heart, and then travels to the brain to cause a blockage.

Ischemic strokes have many potential causes. Excessive blood cholesterol will cause the arteries to narrow and eventually become blocked—resulting in a thrombotic stroke. Blood clots that form in the heart are another cause of ischemic strokes. This occurs when blood clot forms in the heart and then travels to the head, blocking blood supply to the brain. This type of stroke would be an embolic stroke. Blood clots in the heart are more likely to form in people who have irregular heartbeats, have had a heart attack, or have diseased heart valves. Other causes of ischemic strokes include street drug use, traumatic injury to the blood vessels of the neck, and blood clotting disorders.

The risk for stroke is higher in older adults, women, and individuals of African heritage. Other risk factors include high blood pressure, heart disease, smoking, or diabetes. Emergency personnel should be called immediately if you think that you or someone around you is experiencing a stroke. There are a number of complications that can occur after a stroke. Support groups are a great resource for more information and resources.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

Logo
National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ischemic stroke" returned 3610 free, full-text research articles on human participants. First 3 results:

Association of CYP2J2 gene polymorphisms with ischemic stroke and stroke subtypes in Chinese population.
 

Author(s): Si-Yang Wang, Peng-Fei Xing, Chun-Yang Zhang, Ben-Qiang Deng

Journal: Medicine (Baltimore). 2017 Mar;96(10):e6266.

 

Ischemic stroke (IS) is the main cause of mortality and disability among the old people in China and is a multifactorial disease influenced by many factors including genetic factors like the allele for CYP 2J2. It has been demonstrated that CYP2J2 polymorphisms alter the transcriptional ...

Last Updated: 8 Mar 2017

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Objective Ventricle Segmentation in Brain CT with Ischemic Stroke Based on Anatomical Knowledge.
 

Author(s): Xiaohua Qian, Yuan Lin, Yue Zhao, Xinyan Yue, Bingheng Lu, Jing Wang

Journal: Biomed Res Int. 2017 ;2017():8690892.

 

Ventricle segmentation is a challenging technique for the development of detection system of ischemic stroke in computed tomography (CT), as ischemic stroke regions are adjacent to the brain ventricle with similar intensity. To address this problem, we developed an objective segmentation ...

Last Updated: 8 Mar 2017

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Progressive Ischemic Stroke due to Thyroid Storm-Associated Cerebral Venous Thrombosis.
 

Author(s): Natsumi Tanabe, Eiji Hiraoka, Masataka Hoshino, Gautam A Deshpande, Kana Sawada, Yasuhiro Norisue, Jumpei Tsukuda, Toshihiko Suzuki

Journal:

 

BACKGROUND Cerebral venous thrombosis (CVT) is a rare but fatal complication of hyperthyroidism that is induced by the hypercoagulable state of thyrotoxicosis. Although it is frequently difficult to diagnose CVT promptly, it is important to consider it in the differential diagnosis ...

Last Updated: 23 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ischemic stroke" returned 458 free, full-text review articles on human participants. First 3 results:

Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research.
 

Author(s): Cesar Reis, Onat Akyol, Wing Mann Ho, Camila Araujo, Lei Huang, Richard Applegate Ii, John H Zhang

Journal: Biomed Res Int. 2017 ;2017():4863079.

 

Acute ischemic stroke is a devastating cause of death and disability, consequences of which depend on the time from ischemia onset to treatment, the affected brain region, and its size. The main targets of ischemic stroke therapy aim to restore tissue perfusion in the ischemic penumbra ...

Last Updated: 13 Mar 2017

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Association of RAGE gene Gly82Ser polymorphism with coronary artery disease and ischemic stroke: A systematic review and meta-analysis.
 

Author(s): Wen-Qi Ma, Qing-Rong Qu, Yu Zhao, Nai-Feng Liu

Journal: Medicine (Baltimore). 2016 Dec;95(49):e5593.

 

The receptor for advanced glycosylation end products (RAGE) has been widely linked to diabetic atherosclerosis, but its effects on coronary artery disease (CAD) and ischemic stroke (IS) remain controversial. The Gly82Ser polymorphism is located in the ligand-binding V domain of RAGE, ...

Last Updated: 8 Dec 2016

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Dual antiplatelet therapy for secondary stroke prevention: Use of clopidogrel and acetylsalicylic acid after noncardioembolic ischemic stroke.
 

Author(s): Karolina Koziol, Vanessa Van der Merwe, Erin Yakiwchuk, Lynette Kosar

Journal: Can Fam Physician. 2016 Aug;62(8):640-5.

 

Last Updated: 13 Aug 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 19 Apr 2016

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Measuring Collaterals With Multi-phase CT Angiography in Patients With Ischemic Stroke
 

Status: Recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 10 May 2016

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