Ischemic stroke

Common Name(s)

Ischemic stroke

A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. It is said to be the third leading cause of death in the United States. {15:Gunel and Lifton (1996)} noted that about 20% of strokes are hemorrhagic, resulting in bleeding into the brain. Ischemic strokes, resulting from vascular occlusion, account for the majority of strokes. {4:Bersano et al. (2008)} reviewed genetic polymorphisms that have been implicated in the development of stroke. Candidate genes include those involved in hemostasis (see, e.g., F5; {612309}), the renin-angiotensin-aldosterone system (see, e.g., ACE; {106180}), homocysteine (see, e.g., MTHFR; {607093}), and lipoprotein metabolism (see, e.g., APOE; {107741}). See also hemorrhagic stroke, or intracerebral hemorrhage (ICH; {614519}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

Logo
National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ischemic stroke" returned 2721 free, full-text research articles on human participants. First 3 results:

Intraarterial treatment for acute ischemic stroke.
 

Author(s): Olvert A Berkhemer, Charles B L M Majoie, Diederik W J Dippel

Journal: N. Engl. J. Med.. 2015 Mar;372(12):1178-9.

 

Last Updated: 19 Mar 2015

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Regional availability of mechanical embolectomy for acute ischemic stroke in California, 2009 to 2010.
 

Author(s): Jay Chol Choi, Renee Y Hsia, Anthony S Kim

Journal: Stroke. 2015 Mar;46(3):762-8.

 

We sought to assess the geographic proximity of patients with stroke in California to centers that performed specific threshold volumes of mechanical embolectomy procedures each year.

Last Updated: 25 Feb 2015

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Combination therapy of intravenous glycoprotein IIB/IIIA inhibitors and tissue plasminogen activator for acute ischemic stroke.
 

Author(s): Divyanshu Dubey, Chirantan Banerjee, Anshudha Sawhney, Abhishek Sharma, Mark J Alberts

Journal: Neurol India. ;62(6):631-4.

 

Retrospective pooled analysis of data from published prospective studies and randomized phase 1 and 2 trials was done to assess efficacy and safety profile of intravenous combination therapy [glycoprotein IIb/IIIa inhibitors and IV tissue plasminogen activator (tPA)] in management ...

Last Updated: 16 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ischemic stroke" returned 326 free, full-text review articles on human participants. First 3 results:

[Current management of antithrombotic treatment in patients with non valvular atrial fibrillation and prior history of stroke or transient ischemic attack].
 

Author(s): Jaime Masjuán, José Álvarez-Sabín, Miguel Blanco, Alicia de Felipe, Antonio Gil-Núñez, Jaime Gállego-Culleré, José Vivancos

Journal: Rev Neurol. 2014 Jul;59(1):25-36.

 

Atrial fibrillation is the most frequent arrhythmia seen in clinical practice and is one of the most important risk factors for suffering a stroke. Strokes associated to atrial fibrillation are more severe, present higher mortality and disability rates, and there is a greater risk ...

Last Updated: 26 Jun 2014

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Genetics of ischemic stroke in young adults.
 

Author(s): Yu-Ching Cheng, John W Cole, Steven J Kittner, Braxton D Mitchell

Journal: Circ Cardiovasc Genet. 2014 Jun;7(3):383-92.

 

Last Updated: 21 Jun 2014

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Anticoagulation for the acute management of ischemic stroke.
 

Author(s): Austin A Robinson, Kevin Ikuta, Jonathan Soverow

Journal:

 

Few prospective studies support the use of anticoagulation during the acute phase of ischemic stroke, though observational data suggest a role in certain populations. Depending on the mechanism of stroke, systemic anticoagulation may prevent recurrent cerebral infarction, but concomitantly ...

Last Updated: 9 Jun 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

DLBS1033 for Acute Ischemic Stroke Patients
 

Status: Recruiting

Condition Summary: Ischemic Stroke; Partial Anterior Circulation Infarction; Lacunar Infarction by Bamford Criteria

 

Last Updated: 25 Nov 2014

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Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke
 

Status: Recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 13 Apr 2015

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Last Updated: 8 Apr 2015

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