Inflammatory bowel disease 1

Common Name(s)

Inflammatory bowel disease 1

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Inflammatory bowel disease 1" for support, advocacy or research.

Crohn's & Colitis Foundation of America, Inc.

CCFA's mission is to cure Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

Last Updated: 8 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Inflammatory bowel disease 1" for support, advocacy or research.

Crohn's & Colitis Foundation of America, Inc.

CCFA's mission is to cure Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

http://www.ccfa.org

Last Updated: 8 Apr 2014

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Inflammatory bowel disease 1" returned 45 free, full-text research articles on human participants. First 3 results:

Effect of the C3435T polymorphism of the multidrug resistance 1 gene on the severity of inflammatory bowel disease in Iranian Azeri Turks.
 

Author(s): Mortaza J Bonyadi, Sousan M Gerami, Mohammad H Somi, Manouchehr Khoshbaten

Journal: Saudi J Gastroenterol. ;19(4):172-6.

 

Multidrug resistance 1 (MDR1) gene encodes for P-glycoprotein (P-gp), a transmembrane efflux pump transferring both exogenous and endogenous substrate from the cells. In the human gastrointestinal tract, P-gp is found in high concentrations on the epithelial cells of the colon and ...

Last Updated: 5 Jul 2013

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Last Updated: 5 Jul 2013

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NS6180, a new K(Ca) 3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease.
 

Author(s): D Strøbæk, D T Brown, D P Jenkins, Y-J Chen, N Coleman, Y Ando, P Chiu, S Jørgensen, J Demnitz, H Wulff, P Christophersen

Journal: Br. J. Pharmacol.. 2013 Jan;168(2):432-44.

 

The K(Ca) 3.1 channel is a potential target for therapy of immune disease. We identified a compound from a new chemical class of K(Ca) 3.1 inhibitors and assessed in vitro and in vivo inhibition of immune responses.

Last Updated: 2 Jan 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Inflammatory bowel disease 1" returned 3 free, full-text review articles on human participants. First 3 results:

Potential association between TLR4 and chitinase 3-like 1 (CHI3L1/YKL-40) signaling on colonic epithelial cells in inflammatory bowel disease and colitis-associated cancer.
 

Author(s): A Kamba, I-A Lee, E Mizoguchi

Journal: Curr. Mol. Med.. 2013 Aug;13(7):1110-21.

 

Inflammatory bowel disease (IBD) is a group of inflammatory disorders in the small and large intestines. Several studies have proved that persistent and disregulated host/microbial interactions are required for the development of IBD. It is well known that chronic IBD is strongly ...

Last Updated: 22 Jul 2013

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Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis.
 

Author(s): V Annese, M-R Valvano, O Palmieri, A Latiano, F Bossa, A Andriulli

Journal: World J. Gastroenterol.. 2006 Jun;12(23):3636-44.

 

The MDR1 gene is an attractive candidate gene for the pathogenesis of inflammatory bowel disease (IBD) and perhaps response to therapy, with evidences at both functional and genetic levels. Its product, the P-glycoprotein (P-gp) functions as a transmembrane efflux pump thus influencing ...

Last Updated: 14 Jun 2006

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Inflammatory bowel disease Part 1: ulcerative colitis--pathophysiology and conventional and alternative treatment options.
 

Author(s): Kathleen A Head, Julie S Jurenka

Journal: Altern Med Rev. 2003 Aug;8(3):247-83.

 

Ulcerative colitis (UC), a subcategory of inflammatory bowel disease, afflicts 1-2 million people in the United States, and many more worldwide. Although the exact cause of ulcerative colitis remains undetermined, the condition appears to be related to a combination of genetic and ...

Last Updated: 29 Aug 2003

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluate PF-00547659 On Cerebrospinal Fluid Lymphocytes In Volunteers With Crohn's Disease Or Ulcerative Colitis Who Failed Or Did Not Tolerate Anti-TNFs
 

Status: Recruiting

Condition Summary: Crohn's Disease; Ileitis; Ileo-colonic and Colonic Crohn's Disease; Granulomatous Colitis; Regional Enteritis; Ulcerative Colitis

 

Last Updated: 12 Aug 2014

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High-dose Cyclophosphamide for Severe Refractory Crohn Disease
 

Status: Not yet recruiting

Condition Summary: Crohn's Disease; Crohn Disease

 

Last Updated: 18 May 2013

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Immune Regulation in Ulcerative Colitis or Crohn s Disease
 

Status: Recruiting

Condition Summary: Crohn's Disease; Inflammatory Bowel Disease; Ulcerative Colitis

 

Last Updated: 12 Apr 2014

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