Blastoma

Common Name(s)

Blastoma

Blastoma is abnormal cell growth of precursor or immature cells. These cells have yet to develop into cells with specific organ function. As a result, the symptoms that arise from these tumors vary greatly, since they are determined by their location in the body. Blastomas can occur in every part of the body, such as the brain, liver, kidneys, nervous system, bones and even the retina. Blastomas are usually found in children and are harder to diagnose due to their variability. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. If blastomas are found, doctors may suggest chemotherapy to combat the tumor problems.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Blastoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Blastoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Blastoma" returned 48 free, full-text research articles on human participants. First 3 results:

Reply: Serum microRNA screening for DICER1-associated pleuropulmonary blastoma.
 

Author(s): Kris Ann P Schultz, Anne Harris, Gretchen M Williams, Shari Baldinger, Leslie Doros, Patricia Valusek, A Lindsay Frazier, Louis P Dehner, Yoav Messinger, D Ashley Hill

Journal: Pediatr Blood Cancer. 2014 Dec;61(12):2331-2.

 

Last Updated: 20 Oct 2014

Go To URL
Nasal chondromesenchymal hamartomas arise secondary to germline and somatic mutations of DICER1 in the pleuropulmonary blastoma tumor predisposition disorder.
 

Author(s): Douglas R Stewart, Yoav Messinger, Gretchen M Williams, Jiandong Yang, Amanda Field, Kris Ann P Schultz, Laura A Harney, Leslie A Doros, Louis P Dehner, D Ashley Hill

Journal: Hum. Genet.. 2014 Nov;133(11):1443-50.

 

Nasal chondromesenchymal hamartoma (NCMH) is a rare nasal tumor that typically presents in young children. We previously reported on NCMH occurrence in children with pleuropulmonary blastoma (PPB), a rare pulmonary dysembryonic sarcoma that is the hallmark neoplasm in the PPB-associated ...

Last Updated: 4 Oct 2014

Go To URL
Type III pleuropulmonary blastoma in a 7-month-old female baby with impending respiratory failure: a case report.
 

Author(s): Agnese Castro, Chiara Franzonello, Salvatore Leonardi, Andrea Di Cataldo, Enrico Potenza, Gaetano Magro, Giovanni A Rossi, Mario La Rosa

Journal:

 

Pleuropulmonary blastoma is a very rare, aggressive, embryonal pulmonary neoplasm which mostly affects children under the age of 5. According to the histopathological features, three subtypes of pleuropulmonary blastoma have been recognized: type I (purely cystic), type II (grossly ...

Last Updated: 15 Aug 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Blastoma" returned 1 free, full-text review articles on human participants. First 3 results:

Pulmonary blastoma: a case report and review of the literature.
 

Author(s): Robert J Smyth, Aurelie Fabre, Johnathan D Dodd, Waldemar Bartosik, Charles G Gallagher, Edward F McKone

Journal:

 

Pulmonary blastomas are a rare aggressive neoplasm comprising 0.25-0.5% of all primary lung tumors and portend a poor prognosis. They display a biphasic histology with mesenchymal and epithelial components. Historically, the term pulmonary blastoma had included both pure fetal adenocarcinomas, ...

Last Updated: 4 Jun 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

International Pleuropulmonary Blastoma (PPB) Treatment and Biology Registry
 

Status: Recruiting

Condition Summary: Pleuropulmonary Blastoma

 

Last Updated: 3 Feb 2015

Go to URL
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study
 

Status: Recruiting

Condition Summary: Pleuropulmonary Blastoma; Cystic Nephroma; Ovarian Sertoli-Leydig Cell Tumors; Ocular Medulloepithelioma; Nasal Chondromesenchymal Hamartoma

 

Last Updated: 7 Apr 2015

Go to URL
Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome
 

Status: Recruiting

Condition Summary: Pleuropulmonary Blastoma; Cystic Nephroma; Sertoli-Leydig Cell Tumor of Ovary; Medulloepithelioma; Embryonal Rhabdomyosarcoma of Cervix

 

Last Updated: 19 May 2015

Go to URL