Acanthamoeba Infection

Common Name(s)

Acanthamoeba Infection

Acanthamoeba infections are caused by the acanthamoeba bacteria, which are found worldwide in soil and water environments. This bacteria can be spread through contact lens use, cuts, or skin wounds or by being inhaled into the lungs. Many people will encounter this bacteria and experience no harm, however there are three rare diseases that can be caused by the bacteria. Acanthamoeba keratitis is an eye infection that can cause permanent visual impairment or complete blindness. Granulomatous amebic encephalitis is a serious infection of the brain or spinal cord. Disseminated infections (or infections spread throughout the body or an organ of the body) by acanthamoeba can affect the skin, lungs, sinuses and organs.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acanthamoeba Infection" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acanthamoeba Infection" returned 22 free, full-text research articles on human participants. First 3 results:

A Rabbit Model of Acanthamoeba Keratitis That Better Reflects the Natural Human Infection.
 

Author(s): Xianmin Feng, Wenyu Zheng, Yuehua Wang, Donghai Zhao, Xiaoming Jiang, Shijie Lv

Journal: Anat Rec (Hoboken). 2015 Aug;298(8):1509-17.

 

Acanthamoeba species are ubiquitous, free-living protozoa that can invade the cornea and result in Acanthamoeba keratitis (AK), a painful progressive sight-threatening corneal disease. Disease progression in current animal models is too rapid to mimic AK in humans accurately. This ...

Last Updated: 15 Jul 2015

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Rapidly fatal cerebral Acanthamoeba infection after total artificial heart implantation.
 

Author(s):

Journal: Clin. Infect. Dis.. 2014 Dec;59(12):iv.

 

Last Updated: 8 Jan 2015

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Multiple Legionella pneumophila Type II secretion substrates, including a novel protein, contribute to differential infection of the amoebae Acanthamoeba castellanii, Hartmannella vermiformis, and Naegleria lovaniensis.
 

Author(s): Jessica Y Tyson, Meghan M Pearce, Paloma Vargas, Sreya Bagchi, Brendan J Mulhern, Nicholas P Cianciotto

Journal: Infect. Immun.. 2013 May;81(5):1399-410.

 

Type II protein secretion (T2S) by Legionella pneumophila is required for intracellular infection of host cells, including macrophages and the amoebae Acanthamoeba castellanii and Hartmannella vermiformis. Previous proteomic analysis revealed that T2S by L. pneumophila 130b mediates ...

Last Updated: 16 Apr 2013

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Reviews from the PubMed Database

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The terms "Acanthamoeba Infection" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Retrospective Study of Acanthamoebic Keratitis During the Past 10 Years
 

Status: Recruiting

Condition Summary: Acanthamoeba Keratitis

 

Last Updated: 5 May 2016

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