Acanthamoeba Infection

Common Name(s)

Acanthamoeba Infection

Acanthamoeba infections are caused by the acanthamoeba bacteria, which are found worldwide in soil and water environments. This bacteria can be spread through contact lens use, cuts, or skin wounds or by being inhaled into the lungs. Many people will encounter this bacteria and experience no harm, however there are three rare diseases that can be caused by the bacteria. Acanthamoeba keratitis is an eye infection that can cause permanent visual impairment or complete blindness. Granulomatous amebic encephalitis is a serious infection of the brain or spinal cord. Disseminated infections (or infections spread throughout the body or an organ of the body) by acanthamoeba can affect the skin, lungs, sinuses and organs.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acanthamoeba Infection" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acanthamoeba Infection" returned 19 free, full-text research articles on human participants. First 3 results:

Multiple Legionella pneumophila Type II secretion substrates, including a novel protein, contribute to differential infection of the amoebae Acanthamoeba castellanii, Hartmannella vermiformis, and Naegleria lovaniensis.
 

Author(s): Jessica Y Tyson, Meghan M Pearce, Paloma Vargas, Sreya Bagchi, Brendan J Mulhern, Nicholas P Cianciotto

Journal: Infect. Immun.. 2013 May;81(5):1399-410.

 

Type II protein secretion (T2S) by Legionella pneumophila is required for intracellular infection of host cells, including macrophages and the amoebae Acanthamoeba castellanii and Hartmannella vermiformis. Previous proteomic analysis revealed that T2S by L. pneumophila 130b mediates ...

Last Updated: 16 Apr 2013

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Balamuthia mandrillaris and Acanthamoeba amebic encephalitis with neurotoxoplasmosis coinfection in a patient with advanced HIV infection.
 

Author(s): Paula Pietrucha-Dilanchian, Joseph C Chan, Amilcar Castellano-Sanchez, Alicia Hirzel, Panthipa Laowansiri, Claudio Tuda, Govinda S Visvesvara, Yvonne Qvarnstrom, Kenneth R Ratzan

Journal: J. Clin. Microbiol.. 2012 Mar;50(3):1128-31.

 

We describe a patient with advanced HIV infection and Balamuthia mandrillaris and Acanthamoeba amebic encephalitis with Toxoplasma gondii coinfection. A multidisciplinary effort and state-of-the-art diagnostic techniques were required for diagnosis. Our patient is the first reported ...

Last Updated: 20 Feb 2012

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Acanthamoeba produces disseminated infection in locusts and traverses the locust blood-brain barrier to invade the central nervous system.
 

Author(s): Parisa N Mortazavi, Graham Goldsworthy, Ruth Kirk, Naveed A Khan

Journal:

 

Many aspects of Acanthamoeba granulomatous encephalitis remain poorly understood, including host susceptibility and chronic colonization which represent important features of the spectrum of host-pathogen interactions. Previous studies have suggested locusts as a tractable model in ...

Last Updated: 28 Jul 2010

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Reviews from the PubMed Database

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The terms "Acanthamoeba Infection" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.