Hereditary diffuse gastric cancer
Common Name(s)
Hereditary diffuse gastric cancer
Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Hereditary diffuse gastric cancer" for support, advocacy or research.
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Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Hereditary diffuse gastric cancer" for support, advocacy or research.
Recommended Apps
Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.
Finding the right clinical trial for Hereditary diffuse gastric cancer can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Scientific Literature
Articles from the PubMed Database
Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hereditary diffuse gastric cancer" returned 23 free, full-text research articles on human participants.
First 3 results:
Journal: Eur. J. Hum. Genet.. 2013 Aug;21(8):.
Journal: Cancer Epidemiol. Biomarkers Prev.. 2012 Dec;21(12):2272-4.
Approximately one third of the hereditary diffuse gastric cancer (HDGC) families carry germline mutations in the E-cadherin gene (CDH1). Risk prediction in members of families with this rare but deadly cancer could be improved by the identification of additional HDGC genes in non-CDH1 families.
Journal: Rev Esp Enferm Dig. 2012 Jun;104(6):326-9.
The main goal at a High-Risk Gastrointestinal Cancer Clinic is to identify individuals at increased risk of developing tumors for diagnosis them in presymptomatic stages, when they are potentially curable. We report an asymptomatic patient belonging to a family with hereditary diffuse ...
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Reviews from the PubMed Database
Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hereditary diffuse gastric cancer" returned 4 free, full-text review articles on human participants.
First 3 results:
Journal: Clin Med Res. 2013 Feb;11(1):36-41.
Hereditary diffuse gastric cancer (HDGC) is a rare cancer representing approximately 2% of all gastric cancers. It is caused by CDHI gene mutations, inherited in an autosomal dominant fashion, that affect the function of E-cadherin. Approximately 38% of HDGC families have a CDHI gene ...
Journal: Surg. Clin. North Am.. 2008 Aug;88(4):759-78, vi-vii.
Hereditary diffuse gastric cancer (HDGC) is an autosomal dominantly inherited syndrome attributed to mutations of the E-cadherin gene, CDH1. There is no proven effective screening for early HDGC, and symptomatic disease is almost universally fatal. The only available effective option ...
Journal: Fam. Cancer. 2008 ;7(1):73-82.
Hereditary diffuse gastric cancer (HDGC) has been shown to be caused by germline mutations in the gene CDH1 located at 16q22.1, which encodes the cell-cell adhesion molecule, E-cadherin. Not only does loss of expression of E-cadherin account for the morphologic differences between ...
To view other free, full-text review articles on human participants, please click on the link below.
Symptoms, Diagnosis, and Treatment
Clinical Trial Information This information is provided by ClinicalTrials.gov
There are currently no open clinical trials for this condition.
Finding the right clinical trial for Hereditary diffuse gastric cancer can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.