Hereditary diffuse gastric cancer
Common Name(s)
Hereditary diffuse gastric cancer, HDGC
Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Hereditary diffuse gastric cancer" for support, advocacy or research.
Our mission is to support research and united the caring power of people worldwide affected by stomach cancer. We advance awareness and education about stomach cancer, including Hereditary Diffuse Gastric Cancer (HDGC), provide a support network for affected families, and support research for screening, early detection, treatment, and prevention of stomach cancer.
How do you compare to others with this condition?
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Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Hereditary diffuse gastric cancer" for support, advocacy or research.
Our mission is to support research and united the caring power of people worldwide affected by stomach cancer. We advance awareness and education about stomach cancer, including Hereditary Diffuse Gastric Cancer (HDGC), provide a support network for affected families, and support research for screening, early detection, treatment, and prevention of stomach cancer.
http://www.nostomachforcancer.orgRecommended Apps
Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.
Finding the right clinical trial for Hereditary diffuse gastric cancer can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Scientific Literature
Articles from the PubMed Database
Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hereditary diffuse gastric cancer" returned 27 free, full-text research articles on human participants.
First 3 results:
Journal:
Patients with hereditary diffuse gastric cancer (HDGC), a cancer predisposition syndrome associated with germline mutations of the CDH1 (E-cadherin) gene, have few effective treatment options. Despite marked differences in natural history, histopathology, and genetic profile to patients ...
Journal: Arq Bras Cir Dig. ;28(2):149-51.
Journal: Hawaii J Med Public Health. 2014 Jul;73(7):204-7.
Hereditary diffuse gastric cancer (HDGC) is an autosomal dominate cancer syndrome that leads to an increased risk of developing invasive diffuse type (signet ring cell) gastric carcinoma. Approximately 30% of HDGC cases are caused by a germline mutation involving the E-cadherin (CDH1) ...
To view other free, full-text articles on human participants, please click on the link below.
Reviews from the PubMed Database
Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hereditary diffuse gastric cancer" returned 6 free, full-text review articles on human participants.
First 3 results:
Journal: J. Med. Genet.. 2015 Jun;52(6):361-74.
Germline CDH1 mutations confer a high lifetime risk of developing diffuse gastric (DGC) and lobular breast cancer (LBC). A multidisciplinary workshop was organised to discuss genetic testing, surgery, surveillance strategies, pathology reporting and the patient's perspective on multiple ...
Journal: Clin Med Res. 2013 Feb;11(1):36-41.
Hereditary diffuse gastric cancer (HDGC) is a rare cancer representing approximately 2% of all gastric cancers. It is caused by CDHI gene mutations, inherited in an autosomal dominant fashion, that affect the function of E-cadherin. Approximately 38% of HDGC families have a CDHI gene ...
Journal: Cancer Sci.. 2009 Jul;100(7):1151-7.
Hereditary diffuse gastric cancer is a cancer syndrome caused by germline mutations in the gene for the cell adhesion protein E-cadherin (CDH1). E-cadherin plays a central role in the maintenance of cell polarity and its loss during tumorigenesis is associated with poorly differentiated ...
To view other free, full-text review articles on human participants, please click on the link below.
Symptoms, Diagnosis, and Treatment
https://ghr.nlm.nih.gov/condition/breast-cancer
https://ghr.nlm.nih.gov/gene/CDH1
https://ghr.nlm.nih.gov/gene/FGFR4
https://ghr.nlm.nih.gov/condition/prostate-cancer
https://ghr.nlm.nih.gov/condition/ovarian-cancer
https://ghr.nlm.nih.gov/condition/lynch-syndrome
https://ghr.nlm.nih.gov/gene/IRF1
https://ghr.nlm.nih.gov/condition/adult-onset-leukoencephalopathy-with-axonal-spheroids-and-pigmented-glia
https://ghr.nlm.nih.gov/gene/CASP10
https://ghr.nlm.nih.gov/gene/IL1RN
https://ghr.nlm.nih.gov/condition/hereditary-pancreatitis
https://ghr.nlm.nih.gov/condition/hereditary-leiomyomatosis-and-renal-cell-cancer
https://ghr.nlm.nih.gov/gene/BRCA2
https://ghr.nlm.nih.gov/gene/BRCA1
https://ghr.nlm.nih.gov/condition/lung-cancer
https://ghr.nlm.nih.gov/condition/bladder-cancer
https://ghr.nlm.nih.gov/condition/parathyroid-cancer
https://ghr.nlm.nih.gov/gene/RPL15
https://ghr.nlm.nih.gov/condition/retinoblastoma
Clinical Trial Information This information is provided by ClinicalTrials.gov
There are currently no open clinical trials for this condition.

Finding the right clinical trial for Hereditary diffuse gastric cancer can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.