Heme oxygenase 1 deficiency

Common Name(s)

Heme oxygenase 1 deficiency

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heme oxygenase 1 deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Heme oxygenase 1 deficiency" returned 4 free, full-text research articles on human participants. First 3 results:

Induction of Heme Oxygenase-1 Deficiency and Associated Glutamate-Mediated Neurotoxicity Is a Highly Conserved HIV Phenotype of Chronic Macrophage Infection That Is Resistant to Antiretroviral Therapy.
 

Author(s): Alexander J Gill, Colleen E Kovacsics, Patricia J Vance, Ronald G Collman, Dennis L Kolson

Journal: J. Virol.. 2015 Oct;89(20):10656-67.

 

Expression of the cytoprotective enzyme heme oxygenase-1 (HO-1) is significantly reduced in the brain prefrontal cortex of HIV-positive individuals with HIV-associated neurocognitive disorders (HAND). Furthermore, this HO-1 deficiency correlates with brain viral load, markers of macrophage ...

Last Updated: 23 Sep 2015

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Heme oxygenase-1 deficiency accompanies neuropathogenesis of HIV-associated neurocognitive disorders.
 

Author(s): Alexander J Gill, Colleen E Kovacsics, Stephanie A Cross, Patricia J Vance, Lorraine L Kolson, Kelly L Jordan-Sciutto, Benjamin B Gelman, Dennis L Kolson

Journal: J. Clin. Invest.. 2014 Oct;124(10):4459-72.

 

Heme oxygenase-1 (HO-1) is an inducible, detoxifying enzyme that is critical for limiting oxidative stress, inflammation, and cellular injury within the CNS and other tissues. Here, we demonstrate a deficiency of HO-1 expression in the brains of HIV-infected individuals. This HO-1 ...

Last Updated: 2 Oct 2014

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Hepcidin suppression and defective iron recycling account for dysregulation of iron homeostasis in heme oxygenase-1 deficiency.
 

Author(s): Apriliana E R Kartikasari, Frank A D T G Wagener, Akihiro Yachie, Erwin T G Wiegerinck, Erwin H J M Kemna, Dorine W Swinkels, Dorine W Winkels

Journal: J. Cell. Mol. Med.. 2009 Sep;13(9B):3091-102.

 

Heme oxygenase-1 (HO-1) contribution to iron homeostasis has been postulated, because it facilitates iron recycling by liberating iron mostly from heme catabolism. This enzyme also appears to be responsible for the resolution of inflammatory conditions. In a patient with HO-1 deficiency, ...

Last Updated: 3 Mar 2010

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Reviews from the PubMed Database

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The terms "Heme oxygenase 1 deficiency" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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