Bipolar disorder

Common Name(s)

Bipolar disorder, Manic depression

Bipolar disorder is a type of mental illness that causes unusual shifts in mood, energy, activity levels, sleep and behavior. Signs and symptoms typically include alternating periods of manic episodes (joyful or excited states) and depressive episodes (very sad, hopeless or empty states). Mood episodes may also include symptoms of both mania and depression (a mixed state). Bipolar disorder often develops in the late teens or early adult years, but age of onset can range from childhood to late in life. Bipolar disorder can run in families, although no single gene is thought to cause the condition. Many factors acting together may increase a person's risk to develop the disorder. Treatment may include medication and psychotherapy for preventing relapses and reducing the severity of symptoms.

Bipolar disorder differs significantly from clinical depression, although the symptoms for the depressive phase of the illness are similar (please also see: depression). The mood swings from high to low can be severe, ranging from extreme energy to deep despair. The severity of the mood swings and the way they disrupt normal life activities distinguish bipolar mood episodes from ordinary mood changes. It is important to tell your doctor if you experience both highs and lows because the treatment for bipolar disorder is different than for depression. Talk with your doctor to decide on the best treatment plan. Support groups are also a good source of up to date information and can help connect you with others affected by depression.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bipolar disorder" for support, advocacy or research.

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Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

Last Updated: 24 Jun 2015

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Depression and Bipolar Support Alliance

The mission of DBSA is to provide hope, help, support and education to improve the lives of people who have mood disorders.

Last Updated: 15 Apr 2014

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everyminute.org

everyminute.org is a grassroots campaign uniting advocates, mental health professionals and organizations into a single coalition creating a public forum advancing the need and benefit of increased mental health research.

Last Updated: 25 Mar 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

Last Updated: 20 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bipolar disorder" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

http://www.adaa.org

Last Updated: 24 Jun 2015

View Details
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Depression and Bipolar Support Alliance

The mission of DBSA is to provide hope, help, support and education to improve the lives of people who have mood disorders.

http://www.ndmda.org

Last Updated: 15 Apr 2014

View Details
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everyminute.org

everyminute.org is a grassroots campaign uniting advocates, mental health professionals and organizations into a single coalition creating a public forum advancing the need and benefit of increased mental health research.

http://www.everyminute.org

Last Updated: 25 Mar 2013

View Details
National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

View Details
Logo
Simons VIP Connect

The Simons Variation in Individuals Project (Simons VIP) is an online community and research initiative. We provide a platform to partner families and researchers to better understand over 40 genetic changes (genomic variants) associated with features related to autism and developmental delay.

http://www.simonsvipconnect.org

Last Updated: 20 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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General Resources

Bipolar Disorder

A brochure for individuals and families outlining symptoms, causes, treatment and recovery supports.

Updated 29 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bipolar disorder" returned 2200 free, full-text research articles on human participants. First 3 results:

Screening of the unrecognised bipolar disorders among outpatients with recurrent depressive disorder: a cross-sectional study in psychiatric hospital in Morocco.
 

Author(s): Oneib Bouchra, Sabir Maria, Ouanass Abderazak

Journal:

 

The bipolar disorder is often misdiagnosed in particular among outpatients with recurrent depression. Indeed, this work confirmed that the unrecognised bipolar disorder is common among depressed outpatients, which were younger, unemployed, single or divorced with a low socio-economic ...

Last Updated: 5 Oct 2017

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Neuropsychological functioning, age, and medication adherence in bipolar disorder.
 

Author(s): Nadia Corréard, Julia-Lou Consoloni, Aurélie Raust, Bruno Etain, Romain Guillot, Sophie Job, Joséphine Loftus, Isabelle Médecin, Thierry Bougerol, Mircea Polosan, Benjamin Fredembach, Sébastien Gard, Katia M'Bailara, Jean-Pierre Kahn, Paul Roux, Anne-Sophie Homassel, Mathilde Carminati, Lucile Matos, Emilie Olié, Frank Bellivier, Philippe Courtet, Chantal Henry, Marion Leboyer, Jean-Michel Azorin, Raoul Belzeaux,

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Poor adherence to medication is frequent in bipolar disorder (BD) and has been associated with several factors. To date, the relationship between low adherence and neuropsychological functioning in BD is still unclear. As age and neuropsychological functioning might have opposing ...

Last Updated: 5 Sep 2017

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Similar white matter changes in schizophrenia and bipolar disorder: A tract-based spatial statistics study.
 

Author(s): Letizia Squarcina, Marcella Bellani, Maria Gloria Rossetti, Cinzia Perlini, Giuseppe Delvecchio, Nicola Dusi, Marco Barillari, Mirella Ruggeri, Carlo A Altamura, Alessandra Bertoldo, Paolo Brambilla

Journal:

 

Several strands of evidence reported a significant overlapping, in terms of clinical symptoms, epidemiology and treatment response, between the two major psychotic disorders-Schizophrenia (SCZ) and Bipolar Disorder (BD). Nevertheless, the shared neurobiological correlates of these ...

Last Updated: 28 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bipolar disorder" returned 413 free, full-text review articles on human participants. First 3 results:

Use of the MATRICS consensus cognitive battery (MCCB) to evaluate cognitive deficits in bipolar disorder: A systematic review and meta-analysis.
 

Author(s): Qijing Bo, Zhen Mao, Xianbin Li, Zhimin Wang, Chuanyue Wang, Xin Ma

Journal:

 

The Measurement and Treatment Research to Improve Cognition Schizophrenia Consensus Cognitive Battery (MCCB) has also been proposed for use in clinical trials to assess cognitive deficits in patients with bipolar disorder (BD). The aim of this study was to evaluate cognitive function ...

Last Updated: 24 Apr 2017

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Neurodevelopmental Versus Neurodegenerative Model of Schizophrenia and Bipolar Disorder: Comparison with Physiological Brain Development and Aging.
 

Author(s): Massimiliano Buoli, Marta Serati, Alice Caldiroli, Laura Cremaschi, Alfredo Carlo Altamura

Journal: Psychiatr Danub. 2017 Mar;29(1):24-27.

 

Available data support a contribution of both neurodevelopmental and neurodegenerative factors in the etiology of schizophrenia (SCH) and bipolar disorder (BD). Of note, one of the most important issue of the current psychiatric research is to identify the specific factors that contribute ...

Last Updated: 14 Mar 2017

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The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment.
 

Author(s): A H Ashok, T R Marques, S Jauhar, M M Nour, G M Goodwin, A H Young, O D Howes

Journal: Mol. Psychiatry. 2017 May;22(5):666-679.

 

Bipolar affective disorder is a common neuropsychiatric disorder. Although its neurobiological underpinnings are incompletely understood, the dopamine hypothesis has been a key theory of the pathophysiology of both manic and depressive phases of the illness for over four decades. ...

Last Updated: 14 Mar 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Occupational Stress and Bipolar Disorder
 

Status: Recruiting

Condition Summary: Bipolar Disorder

 

Last Updated: 19 May 2017

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Targeting Cognition in Bipolar Disorder With Pramipexole
 

Status: Recruiting

Condition Summary: Bipolar Disorder

 

Last Updated: 26 Apr 2017

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Study of the Genetic and Environmental Factors of Vulnerability in Bipolar Disorders
 

Status: Recruiting

Condition Summary: Bipolar Disorder

 

Last Updated: 8 Dec 2015

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