Biliary Tract Cancer

Common Name(s)

Biliary Tract Cancer

Bile Tract Cancer is a rare digestive cancer characterized by abnormal cell growth in the bile ducts and gallbladder. Individuals with this disorder may grow harmful tumors that can spread to the rest of the body if not diagnosed early. The bile duct system is responsible for storing and transporting bile from the liver, where it is made, to the intestines, where it helps to digest food. Incomplete development of the ducts inhibits the flow of bile. Individuals with this defect have digestion problems as well as a yellow discoloration of the eye and skin (jaundice). Doctors are usually able to diagnose this defect early in the abnormal growth process, as the resulting symptoms are quickly apparent. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. For prevention measures, digestion specialists may suggest individuals eat a lower-fat diet, or undergo surgery to relieve the blockage or create a tube to allow bile to reach the digestive system. If an individual's cancer has progressed, doctors may suggest chemotherapy to combat cancer symptoms.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Biliary Tract Cancer" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Biliary Tract Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Biliary Tract Cancer" returned 130 free, full-text research articles on human participants. First 3 results:

Predictive Factors of Biliary Tract Cancer in Anomalous Union of the Pancreaticobiliary Duct.
 

Author(s): Jin-Seok Park, Tae Jun Song, Tae Young Park, Dongwook Oh, Hyun Kyo Lee, Do Hyun Park, Sang Soo Lee, Dong Wan Seo, Sung Koo Lee, Myung-Hwan Kim

Journal: Medicine (Baltimore). 2016 May;95(20):e3526.

 

The assessment of malignancies associated with anomalous union of the pancreaticobiliary duct (AUPBD) is essential for the design of appropriate treatment strategies. The aim of the present study is to measure the incidence of AUPBD-related pancreaticobiliary malignancy and to identify ...

Last Updated: 20 May 2016

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The correlation between LDH serum levels and clinical outcome in advanced biliary tract cancer patients treated with first line chemotherapy.
 

Author(s): Luca Faloppi, Michela Del Prete, Andrea Casadei Gardini, Daniele Santini, Nicola Silvestris, Maristella Bianconi, Riccardo Giampieri, Martina Valgiusti, Oronzo Brunetti, Alessandro Bittoni, Kalliopi Andrikou, Eleonora Lai, Alessandra Dessì, Stefano Cascinu, Mario Scartozzi

Journal:

 

LDH may represent an indirect marker of neo-angiogenesis and worse prognosis in many tumour types. We assessed the correlation between LDH and clinical outcome for biliary tract cancer (BTC) patients treated with first-line chemotherapy. Overall, 114 advanced BTC patients treated ...

Last Updated: 11 Apr 2016

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Early Gastric Cancer Recurrence Following Curative Resection Presenting as Biliary Tract Dilatation, Pancreatic Duct Dilatation and Intestinal Wall Thickening.
 

Author(s): Hiroyuki Kato, Yukiko Ito, Eri Tanaka, Kensaku Noguchi, Shinzo Yamamoto, Hiroyoshi Taniguchi, Hideo Yoshida, Toshio Kumasaka, Ryo Nakata

Journal: Intern. Med.. 2016 ;55(7):745-50.

 

Early gastric cancer, especially cancer confined to the mucosa (stage T1a), is known to have a high cure rate with rare recurrence. We herein report the case of a 40-year-old female who initially presented with biliary tract dilatation, pancreatic duct dilatation and intestinal wall ...

Last Updated: 4 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Biliary Tract Cancer" returned 11 free, full-text review articles on human participants. First 3 results:

Deregulated MicroRNAs in Biliary Tract Cancer: Functional Targets and Potential Biomarkers.
 

Author(s): Christian Mayr, Marlena Beyreis, Andrej Wagner, Martin Pichler, Daniel Neureiter, Tobias Kiesslich

Journal: Biomed Res Int. 2016 ;2016():4805270.

 

Biliary tract cancer (BTC) is still a fatal disease with very poor prognosis. The lack of reliable biomarkers for early diagnosis and of effective therapeutic targets is a major demanding problem in diagnosis and management of BTC. Due to the clinically silent and asymptomatic characteristics ...

Last Updated: 13 Dec 2016

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Biliary Tract Cancer: Epidemiology, Radiotherapy, and Molecular Profiling.
 

Author(s): John A Bridgewater, Karyn A Goodman, Aparna Kalyan, Mary F Mulcahy

Journal: Am Soc Clin Oncol Educ Book. 2016 ;35():e194-203.

 

Biliary tract cancer, or cholangiocarcinoma, arises from the biliary epithelium of the small ducts in the periphery of the liver (intrahepatic) and the main ducts of the hilum (extrahepatic), extending into the gallbladder. The incidence and epidemiology of biliary tract cancer are ...

Last Updated: 2 Jun 2016

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[Inflammation and Cancer Development in Pancreatic and Biliary Tract Cancer].
 

Author(s): Sang Hoon Lee, Seung Woo Park

Journal: Korean J Gastroenterol. 2015 Dec;66(6):325-39.

 

Chronic inflammation has been known to be a risk for many kinds of cancers, including pancreatic and biliary tract cancer. Recently, inflammatory process has emerged as a key mediator of cancer development and progression. Many efforts with experimental results have been given to ...

Last Updated: 22 Dec 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

MEK162 in Combination With Capecitabine in Advanced Biliary Tract Cancer
 

Status: Recruiting

Condition Summary: Biliary Tract Cancer

 

Last Updated: 15 May 2016

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Last Updated: 1 Feb 2017

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A Phase II Trial of Preoperative Chemotherapy for Biliary Tract Cancer (BTC) With Node Metastasis
 

Status: Recruiting

Condition Summary: Biliary Tract Cancer

 

Last Updated: 31 Aug 2016

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