Essential hypertension

Common Name(s)

Essential hypertension

The Pickering school held that blood pressure has a continuous distribution, that multiple genes and multiple environmental factors determine the level of one's blood pressure just as the determination of stature and intelligence is multifactorial, and that 'essential hypertension' is merely the upper end of the distribution ({66:Pickering, 1978}). In this view the person with essential hypertension is one who happens to inherit an aggregate of genes determining hypertension (and also is exposed to exogenous factors that favor hypertension). The Platt school took the view that essential hypertension is a simple mendelian dominant trait ({69:Platt, 1963}). {57:McDonough et al. (1964)} defended the monogenic idea. See {58:McKusick (1960)} and {52:Kurtz and Spence (1993)} for reviews. {78:Swales (1985)} reviewed the Platt-Pickering controversy as an 'episode in recent medical history.' The Pickering point of view appears to be more consistent with the observations.
 

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Condition Specific Organizations

Following organizations serve the condition "Essential hypertension" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential hypertension" returned 1365 free, full-text research articles on human participants. First 3 results:

micro-RNA screening and prediction model construction for diagnosis of salt-sensitive essential hypertension.
 

Author(s): Han Qi, Zheng Liu, Bin Liu, Han Cao, Weiping Sun, Yuxiang Yan, Ling Zhang

Journal: Medicine (Baltimore). 2017 Apr;96(17):e6417.

 

Commonly used tests for diagnosis of salt-sensitive hypertension (SSH) are complex and time-consuming, so new methods are required. Many studies have demonstrated roles for miRNAs in hypertension; however, the diagnostic value of miRNAs has yet to be determined for human SSH. In this ...

Last Updated: 26 Apr 2017

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Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials.
 

Author(s): Jalal Poorolajal, Fatemeh Zeraati, Ali Reza Soltanian, Vida Sheikh, Elham Hooshmand, Akram Maleki

Journal:

 

Increased dietary potassium intake is thought to be associated with low blood pressure (BP). Whether potassium supplementation may be used as an antihypertensive agent is a question that should be answered.

Last Updated: 18 Apr 2017

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The Relationships between the Differences in the Central Blood Pressure and Brachial Blood Pressure and Other Factors in Patients with Essential Hypertension.
 

Author(s): Masaki Ryuzaki, Satoshi Morimoto, Michita Niiyama, Yasufumi Seki, Naohiro Yoshida, Yoichi Oshima, Yuki Mizuguchi, Daisuke Watanabe, Takashi Ando, Atsuhiro Ichihara

Journal: Intern. Med.. 2017 ;56(6):587-596.

 

Objective The management of blood pressure (BP) in hypertensive patients is the key to preventing a progression of organ damage. The brachial BP (bBP) has been used as the representative method for measuring the BP. The central BP (cBP), which is, different from the bBP due to the ...

Last Updated: 21 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential hypertension" returned 106 free, full-text review articles on human participants. First 3 results:

Epigenetic Modifications in Essential Hypertension.
 

Author(s): Ingrid A Wise, Fadi J Charchar

Journal:

 

Essential hypertension (EH) is a complex, polygenic condition with no single causative agent. Despite advances in our understanding of the pathophysiology of EH, hypertension remains one of the world's leading public health problems. Furthermore, there is increasing evidence that ...

Last Updated: 30 Mar 2016

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Vitamin D deficiency and essential hypertension.
 

Author(s): Songcang Chen, Yingxian Sun, Devendra K Agrawal

Journal: J Am Soc Hypertens. 2015 Nov;9(11):885-901.

 

Essential hypertension (EH) results when the balance between vasoconstriction and vasodilation is shifted in favor of vasoconstriction. This balance is controlled by the interaction of genetic and epigenetic factors. When there is an unstable balance, vitamin D deficiency as an epigenetic ...

Last Updated: 10 Nov 2015

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Associations of pregnancy-associated plasma protein-A level with essential hypertension and hypertensive disorders in pregnancy in Chinese population: a meta-analysis of 20 research studies involving 3332 individuals.
 

Author(s): Gaojun Cai, Bifeng Zhang, Weijin Weng, Liping Yang, Ganwei Shi, Sheliang Xue, Xingli Fu

Journal:

 

To explore the associations between serum pregnancy-associated plasma protein-A (PAPP-A) level, and essential hypertension (EH) and hypertensive disorders in pregnancy (HDP) in Chinese population.

Last Updated: 29 Sep 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Personalized Dietary Intervention for the Control of Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 10 Nov 2015

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Efficacy and Safety of Arotinolol Hydrochloride on Morning Blood Pressure and Heart Rate
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 13 Oct 2016

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Combination of Fimasartan/Amlodipine/Rosuvastatin in Patients With Essential Hypertension and Dyslipidemia
 

Status: Not yet recruiting

Condition Summary: Essential Hypertension; Dyslipidemia

 

Last Updated: 16 May 2017

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