Essential hypertension

Common Name(s)

Essential hypertension

The Pickering school held that blood pressure has a continuous distribution, that multiple genes and multiple environmental factors determine the level of one's blood pressure just as the determination of stature and intelligence is multifactorial, and that 'essential hypertension' is merely the upper end of the distribution ({66:Pickering, 1978}). In this view the person with essential hypertension is one who happens to inherit an aggregate of genes determining hypertension (and also is exposed to exogenous factors that favor hypertension). The Platt school took the view that essential hypertension is a simple mendelian dominant trait ({69:Platt, 1963}). {57:McDonough et al. (1964)} defended the monogenic idea. See {58:McKusick (1960)} and {52:Kurtz and Spence (1993)} for reviews. {78:Swales (1985)} reviewed the Platt-Pickering controversy as an 'episode in recent medical history.' The Pickering point of view appears to be more consistent with the observations.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential hypertension" returned 1278 free, full-text research articles on human participants. First 3 results:

Inverse Correlation Between Plasma Adropin and ET-1 Levels in Essential Hypertension: A Cross-Sectional Study.
 

Author(s): Xiaosong Gu, Hui Li, Xinyi Zhu, Haibo Gu, Jianchang Chen, Luchen Wang, Pamela Harding, Weiting Xu

Journal: Medicine (Baltimore). 2015 Oct;94(40):e1712.

 

Adropin is a recently identified bioactive protein that promotes energy homeostasis by affecting glucose and lipid metabolism. Recently, adropin has also been reported to be associated with endothelial dysfunction. Also, ET-1, as a biomarker for endothelial dysfunction, is a key regulator ...

Last Updated: 9 Oct 2015

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Plasma Metanephrines Are Associated With Glucose Metabolism in Patients With Essential Hypertension.
 

Author(s): Weiqing Wang, Liangshan Mu, Tingwei Su, Lei Ye, Yiran Jiang, Lei Jiang, Weiwei Zhou

Journal: Medicine (Baltimore). 2015 Sep;94(37):e1496.

 

There is a high incidence of glucose intolerance in essential hypertension. Overactivation of the sympathetic system is one of important causes of essential hypertension. Whether sympathetic system affects glucose metabolism in patients with essential hypertension has never been reported ...

Last Updated: 17 Sep 2015

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Relationship between Serum Bilirubin and Left Ventricular Hypertrophy in Patients with Essential Hypertension.
 

Author(s): Tao Zhou, Xiaofang Chen, Zhanzhan Li, Lezhi Li

Journal:

 

Prospective studies have found low bilirubin levels were an important predictive factor of cardiovascular events. However, few have yet investigated possible association between serum bilirubin level and LVH in essential hypertension. The aim of the present study was to evaluate the ...

Last Updated: 28 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential hypertension" returned 101 free, full-text review articles on human participants. First 3 results:

Effects of traditional Chinese patent medicine on essential hypertension: a systematic review.
 

Author(s): Xingjiang Xiong, Pengqian Wang, Yuqing Zhang, Xiaoke Li

Journal: Medicine (Baltimore). 2015 Feb;94(5):e442.

 

Traditional Chinese patent medicine (TCPM) is widely used for essential hypertension (EH) in China. However, there is no critically appraised evidence, such as systematic reviews or meta-analyses, regarding the potential benefits and disadvantages of TCPM to justify their clinical ...

Last Updated: 6 Feb 2015

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The effect of Chinese herbal medicine Jian Ling Decoction for the treatment of essential hypertension: a systematic review.
 

Author(s): Xingjiang Xiong, Pengqian Wang, Xiaoke Li, Yuqing Zhang

Journal:

 

Jian Ling Decoction (JLD) is often prescribed to improve hypertension-related symptoms in China. However, this treatment has not been systematically reviewed for its efficacy against essential hypertension (EH). This review aims to assess the current clinical evidence of JLD in the treatment of EH.

Last Updated: 5 Feb 2015

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Ginkgo biloba extract for essential hypertension: a systemic review.
 

Author(s): X J Xiong, W Liu, X C Yang, B Feng, Y Q Zhang, S J Li, X K Li, J Wang

Journal: Phytomedicine. 2014 Sep;21(10):1131-6.

 

Ginkgo biloba extract (GBE), a traditional natural herbal product, is often used in the treatment of essential hypertension (EH) as complementary therapy in China and European countries.

Last Updated: 25 Jul 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Renal Sympathetic Modification in Patients With Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 2 May 2013

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Early Metabolic Changes With Thiazide or Beta Blocker Therapy for Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 22 Sep 2006

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Last Updated: 21 May 2015

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