Essential hypertension

Common Name(s)

Essential hypertension

The Pickering school held that blood pressure has a continuous distribution, that multiple genes and multiple environmental factors determine the level of one's blood pressure just as the determination of stature and intelligence is multifactorial, and that 'essential hypertension' is merely the upper end of the distribution ({66:Pickering, 1978}). In this view the person with essential hypertension is one who happens to inherit an aggregate of genes determining hypertension (and also is exposed to exogenous factors that favor hypertension). The Platt school took the view that essential hypertension is a simple mendelian dominant trait ({69:Platt, 1963}). {57:McDonough et al. (1964)} defended the monogenic idea. See {58:McKusick (1960)} and {52:Kurtz and Spence (1993)} for reviews. {79:Swales (1985)} reviewed the Platt-Pickering controversy as an 'episode in recent medical history.' The Pickering point of view appears to be more consistent with the observations.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential hypertension" returned 1166 free, full-text research articles on human participants. First 3 results:

Serum uric acid level in newly diagnosed essential hypertension in a Nepalese population: a hospital based cross sectional study.
 

Author(s): Bibek Poudel, Binod Kumar Yadav, Arun Kumar, Bharat Jha, Kanak Bahadur Raut

Journal: Asian Pac J Trop Biomed. 2014 Jan;4(1):59-64.

 

To develop the missing link between hyperuricemia and hypertension.

Last Updated: 22 Oct 2013

Go To URL
A randomized controlled study on the effects of bisoprolol and atenolol on sympathetic nervous activity and central aortic pressure in patients with essential hypertension.
 

Author(s): Wei-Jun Zhou, Ren-Ying Wang, Yan Li, Dong-Rui Chen, Er-Zhen Chen, Ding-Liang Zhu, Ping-Jin Gao

Journal:

 

β-blockers (BBs) with different pharmacological properties may have heterogeneous effects on sympathetic nervous activity (SNA) and central aortic pressure (CAP), which are independent cardiovascular factors for hypertension. Hence, we analyzed the effects of bisoprolol and atenolol ...

Last Updated: 16 Sep 2013

Go To URL
Association between polymorphisms in the renin-angiotensin-aldosterone system genes and essential hypertension in the Han Chinese population.
 

Author(s): Lindan Ji, Xiaobo Cai, Lina Zhang, Lijuan Fei, Lin Wang, Jia Su, Lissy Lazar, Jin Xu, Yaping Zhang

Journal:

 

Renin-angiotensin-aldosterone system (RAAS) is the most important endocrine blood pressure control mechanism in our body, genes encoding components of this system have been strong candidates for the investigation of the genetic basis of hypertension. However, previous studies mainly ...

Last Updated: 9 Sep 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential hypertension" returned 85 free, full-text review articles on human participants. First 3 results:

Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage.
 

Author(s): Ramón Rodrigo, Matías Libuy, Felipe Feliú, Daniel Hasson

Journal: Dis. Markers. 2013 ;35(6):773-90.

 

Cardiovascular diseases are a leading cause of mortality and morbidity worldwide, with hypertension being a major risk factor. Numerous studies support the contribution of reactive oxygen and nitrogen species in the pathogenesis of hypertension, as well as other pathologies associated ...

Last Updated: 18 Dec 2013

Go To URL
Yoga for essential hypertension: a systematic review.
 

Author(s): Jie Wang, Xingjiang Xiong, Wei Liu

Journal:

 

Yoga is thought to be effective for health conditions. The article aims to assess the current clinical evidence of yoga for Essential hypertension (EH).

Last Updated: 14 Oct 2013

Go To URL
STK39 polymorphism is associated with essential hypertension: a systematic review and meta-analysis.
 

Author(s): Bo Xi, Man Chen, Giriraj R Chandak, Yue Shen, Li Yan, Juan He, Si-Hua Mou

Journal: PLoS ONE. 2013 ;8(3):e59584.

 

A recent genome-wide association study identified STK39as a candidate gene for blood pressure (BP) in Europeans. Subsequently, several studies have attempted to replicate the association across different ethnic populations. However, the results have been inconsistent.

Last Updated: 25 Mar 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Renal Sympathetic Modification in Patients With Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 2 May 2013

Go to URL
Early Metabolic Changes With Thiazide or Beta Blocker Therapy for Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 22 Sep 2006

Go to URL
Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Asian Patients With Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 25 Jun 2014

Go to URL