Essential hypertension

Common Name(s)

Essential hypertension

The Pickering school held that blood pressure has a continuous distribution, that multiple genes and multiple environmental factors determine the level of one's blood pressure just as the determination of stature and intelligence is multifactorial, and that 'essential hypertension' is merely the upper end of the distribution ({66:Pickering, 1978}). In this view the person with essential hypertension is one who happens to inherit an aggregate of genes determining hypertension (and also is exposed to exogenous factors that favor hypertension). The Platt school took the view that essential hypertension is a simple mendelian dominant trait ({69:Platt, 1963}). {57:McDonough et al. (1964)} defended the monogenic idea. See {58:McKusick (1960)} and {52:Kurtz and Spence (1993)} for reviews. {79:Swales (1985)} reviewed the Platt-Pickering controversy as an 'episode in recent medical history.' The Pickering point of view appears to be more consistent with the observations.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential hypertension" returned 1156 free, full-text research articles on human participants. First 3 results:

Impact of dairy consumption on essential hypertension: a clinical study.
 

Author(s): Jean-Philippe Drouin-Chartier, Iris Gigleux, André J Tremblay, Luc Poirier, Benoît Lamarche, Patrick Couture

Journal:

 

Several studies have presented evidence suggesting that dairy consumption has beneficial effects on blood pressure (BP) in healthy subjects; however, only a few studies have examined this possibility in patients with established essential hypertension using ambulatory blood pressure ...

Last Updated: 19 Aug 2014

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Measurement of absolute copy number variation reveals association with essential hypertension.
 

Author(s): Francine Z Marques, Priscilla R Prestes, Leonardo B Pinheiro, Katrina Scurrah, Kerry R Emslie, Maciej Tomaszewski, Stephen B Harrap, Fadi J Charchar

Journal:

 

The role of copy number variation (CNV) has been poorly explored in essential hypertension in part due to technical difficulties in accurately assessing absolute numbers of DNA copies. Droplet digital PCR (ddPCR) provides a powerful new approach to CNV quantitation. The aim of our ...

Last Updated: 24 Jul 2014

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Gender specific association of RAS gene polymorphism with essential hypertension: a case-control study.
 

Author(s): Kh Dhanachandra Singh, Ajay Jajodia, Harpreet Kaur, Ritushree Kukreti, Muthusamy Karthikeyan

Journal: Biomed Res Int. 2014 ;2014():538053.

 

Renin-angiotensin system (RAS) polymorphisms have been studied as candidate risk factors for hypertension with inconsistent results, possibly due to heterogeneity among various genetic and environmental factors. A case-control association study was conducted to investigate a possible ...

Last Updated: 26 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential hypertension" returned 87 free, full-text review articles on human participants. First 3 results:

Moxibustion for essential hypertension.
 

Author(s): Xingjiang Xiong, Wei Liu, Xiaochen Yang, Bo Feng, Jie Wang

Journal: Complement Ther Med. 2014 Feb;22(1):187-95.

 

The objective of this review was to assess the current clinical evidence of moxibustion for essential hypertension (EH). 7 electronic databases were searched until March 2013. Randomized clinical trials testing moxibustion, or combined with antihypertensive drugs, against antihypertensive ...

Last Updated: 24 Feb 2014

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Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage.
 

Author(s): Ramón Rodrigo, Matías Libuy, Felipe Feliú, Daniel Hasson

Journal: Dis. Markers. 2013 ;35(6):773-90.

 

Cardiovascular diseases are a leading cause of mortality and morbidity worldwide, with hypertension being a major risk factor. Numerous studies support the contribution of reactive oxygen and nitrogen species in the pathogenesis of hypertension, as well as other pathologies associated ...

Last Updated: 18 Dec 2013

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Yoga for essential hypertension: a systematic review.
 

Author(s): Jie Wang, Xingjiang Xiong, Wei Liu

Journal:

 

Yoga is thought to be effective for health conditions. The article aims to assess the current clinical evidence of yoga for Essential hypertension (EH).

Last Updated: 14 Oct 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Renal Sympathetic Modification in Patients With Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 2 May 2013

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Early Metabolic Changes With Thiazide or Beta Blocker Therapy for Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 22 Sep 2006

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Efficacy and Safety of HL-040XC in Essential Hypertension and Hyperlipidemia
 

Status: Recruiting

Condition Summary: Essential Hypertension; Hyperlipidemia

 

Last Updated: 24 Feb 2014

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