Essential hypertension

Common Name(s)

Essential hypertension

The Pickering school held that blood pressure has a continuous distribution, that multiple genes and multiple environmental factors determine the level of one's blood pressure just as the determination of stature and intelligence is multifactorial, and that 'essential hypertension' is merely the upper end of the distribution ({66:Pickering, 1978}). In this view the person with essential hypertension is one who happens to inherit an aggregate of genes determining hypertension (and also is exposed to exogenous factors that favor hypertension). The Platt school took the view that essential hypertension is a simple mendelian dominant trait ({69:Platt, 1963}). {57:McDonough et al. (1964)} defended the monogenic idea. See {58:McKusick (1960)} and {52:Kurtz and Spence (1993)} for reviews. {79:Swales (1985)} reviewed the Platt-Pickering controversy as an 'episode in recent medical history.' The Pickering point of view appears to be more consistent with the observations.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential hypertension" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential hypertension" returned 1172 free, full-text research articles on human participants. First 3 results:

Serum uric acid and target organ damage in essential hypertension.
 

Author(s): Sandra N Ofori, Osaretin J Odia

Journal:

 

Hypertension is a major risk factor for cardiovascular mortality, as it acts through its effects on target organs, such as the heart and kidneys. Hyperuricemia increases cardiovascular risk in patients with hypertension.

Last Updated: 16 May 2014

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Association between human urotensin II and essential hypertension--a 1:1 matched case-control study.
 

Author(s): Hao Peng, Mingzhi Zhang, Xiaoqin Cai, Jennifer Olofindayo, Anna Tan, Yonghong Zhang

Journal:

 

We aimed to evaluate the controversial association between human urotensin II and essential hypertension in untreated hypertensive cases and normotensive controls.

Last Updated: 16 Dec 2013

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Association between the CYP4A11 T8590C variant and essential hypertension: new data from Han Chinese and a meta-analysis.
 

Author(s): Hua-Cheng Yan, Jun-Hua Liu, Jian Li, Bao-Xia He, Liang Yang, Jian Qiu, Liang Li, Da-Peng Ding, Lei Shi, Shu-Jin Zhao

Journal:

 

CYP4A11 oxidizes endogenous arachidonic acid to 20-hydroxyeicosatetraenoic acid, a renal vasoconstrictor and natriuretic in humans. Previous studies demonstrated an association between a functional variant (T8590C) of CYP4A11 and essential hypertension, though with conflicting results. ...

Last Updated: 26 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential hypertension" returned 89 free, full-text review articles on human participants. First 3 results:

Moxibustion for essential hypertension.
 

Author(s): Xingjiang Xiong, Wei Liu, Xiaochen Yang, Bo Feng, Jie Wang

Journal: Complement Ther Med. 2014 Feb;22(1):187-95.

 

The objective of this review was to assess the current clinical evidence of moxibustion for essential hypertension (EH). 7 electronic databases were searched until March 2013. Randomized clinical trials testing moxibustion, or combined with antihypertensive drugs, against antihypertensive ...

Last Updated: 24 Feb 2014

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Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage.
 

Author(s): Ramón Rodrigo, Matías Libuy, Felipe Feliú, Daniel Hasson

Journal: Dis. Markers. 2013 ;35(6):773-90.

 

Cardiovascular diseases are a leading cause of mortality and morbidity worldwide, with hypertension being a major risk factor. Numerous studies support the contribution of reactive oxygen and nitrogen species in the pathogenesis of hypertension, as well as other pathologies associated ...

Last Updated: 18 Dec 2013

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Yoga for essential hypertension: a systematic review.
 

Author(s): Jie Wang, Xingjiang Xiong, Wei Liu

Journal:

 

Yoga is thought to be effective for health conditions. The article aims to assess the current clinical evidence of yoga for Essential hypertension (EH).

Last Updated: 14 Oct 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Renal Sympathetic Modification in Patients With Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 2 May 2013

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Early Metabolic Changes With Thiazide or Beta Blocker Therapy for Essential Hypertension
 

Status: Recruiting

Condition Summary: Essential Hypertension

 

Last Updated: 22 Sep 2006

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Efficacy and Safety of HL-040XC in Essential Hypertension and Hyperlipidemia
 

Status: Recruiting

Condition Summary: Essential Hypertension; Hyperlipidemia

 

Last Updated: 24 Feb 2014

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