Biliary Atresia Extrahepatic

Common Name(s)

Biliary Atresia Extrahepatic

Biliary atresia is a disorder of infants in which there is progressive obliteration or discontinuity of the extrahepatic biliary system, resulting in obstruction of bile flow. Untreated, the resulting cholestasis leads to progressive conjugated hyperbilirubinemia, cirrhosis, and hepatic failure ({1:Bates et al., 1998}). Most patients require liver transplantation within the first year of life ({9:Leyva-Vega et al., 2010}). See also Alagille syndrome ({118450}), which includes biliary atresia as a feature.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Biliary Atresia Extrahepatic" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Biliary Atresia Extrahepatic" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Biliary Atresia Extrahepatic" returned 24 free, full-text research articles on human participants. First 3 results:

Predictive value of hepatic ultrasound, liver biopsy, and duodenal tube test in the diagnosis of extrahepatic biliary atresia in Serbian infants.
 

Author(s): Aleksandra Boskovic, Ivana Kitic, Dragan Prokic, Ivica Stankovic, Blagoje Grujic

Journal: Turk J Gastroenterol. 2014 Apr;25(2):170-4.

 

Extrahepatic biliary atresia (EHBA) is the most important cause of neonatal cholestasis. The validity of different diagnostic methods in the diagnosis of EHBA in developed countries has been presented elsewhere, but data from developing countries with low national incomes are scarce. ...

Last Updated: 9 Jul 2014

Go To URL
Extrahepatic anomalies in infants with biliary atresia: results of a large prospective North American multicenter study.
 

Author(s): Kathleen B Schwarz, Barbara H Haber, Philip Rosenthal, Cara L Mack, Jeffrey Moore, Kevin Bove, Jorge A Bezerra, Saul J Karpen, Nanda Kerkar, Benjamin L Shneider, Yumirle P Turmelle, Peter F Whitington, Jean P Molleston, Karen F Murray, Vicky L Ng, René Romero, Kasper S Wang, Ronald J Sokol, John C Magee,

Journal: Hepatology. 2013 Nov;58(5):1724-31.

 

The etiology of biliary atresia (BA) is unknown. Given that patterns of anomalies might provide etiopathogenetic clues, we used data from the North American Childhood Liver Disease Research and Education Network to analyze patterns of anomalies in infants with BA. In all, 289 infants ...

Last Updated: 20 Jan 2014

Go To URL
Extrahepatic cholangiocyte cilia are abnormal in biliary atresia.
 

Author(s): Sara Karjoo, Nicholas J Hand, Lorena Loarca, Pierre A Russo, Joshua R Friedman, Rebecca G Wells

Journal: J. Pediatr. Gastroenterol. Nutr.. 2013 Jul;57(1):96-101.

 

Biliary atresia (BA) is a rapidly progressive form of biliary fibrosis affecting neonates. We previously reported that primary cilia on the intrahepatic cholangiocytes of patients with both syndromic and nonsyndromic BA were structurally abnormal. Our objective was to determine whether ...

Last Updated: 26 Jun 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Biliary Atresia Extrahepatic" returned 3 free, full-text review articles on human participants. First 3 results:

Extrahepatic biliary atresia: current concepts and future directions.
 

Author(s): Elisa de Carvalho, Cláudia Alexandra Pontes Ivantes, Jorge A Bezerra

Journal: J Pediatr (Rio J). ;83(2):105-20.

 

To provide an updated review on extrahepatic biliary atresia, focusing mainly on its etiopathogenesis, diagnosis, treatment and prognosis.

Last Updated: 11 Apr 2007

Go To URL
[Extrahepatic biliary atresia: diagnostic methods].
 

Author(s): Sydney M Cauduro

Journal: J Pediatr (Rio J). ;79(2):107-14.

 

To emphasize the importance of precocious diagnosis of extrahepatic biliary atresia and its direct relationship with the surgical re-establishment of the biliary flow before the second month of life. To discuss several complementary methods with the aim of selecting the ones that ...

Last Updated: 22 Sep 2003

Go To URL
Extrahepatic biliary atresia. Recent developments in management.
 

Author(s): E R Howard, A P Mowat

Journal: Arch. Dis. Child.. 1977 Nov;52(11):825-7.

 

Last Updated: 23 Feb 1978

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Biliary Atresia Study in Infants and Children
 

Status: Recruiting

Condition Summary: Biliary Atresia

 

Last Updated: 15 Sep 2014

Go to URL
Pentoxifylline Therapy in Biliary Atresia
 

Status: Recruiting

Condition Summary: Biliary Atresia

 

Last Updated: 5 Feb 2015

Go to URL
Evaluation of Immune Function in Biliary Atresia Children With Prolonged Jaundice
 

Status: Recruiting

Condition Summary: Biliary Atresia

 

Last Updated: 9 Sep 2005

Go to URL