Dimethylglycine dehydrogenase deficiency

Common Name(s)

Dimethylglycine dehydrogenase deficiency

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dimethylglycine dehydrogenase deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dimethylglycine dehydrogenase deficiency" returned 2 free, full-text research articles on human participants. First 3 results:

Molecular basis of dimethylglycine dehydrogenase deficiency associated with pathogenic variant H109R.
 

Author(s): R P McAndrew, J Vockley, J-J P Kim

Journal: J. Inherit. Metab. Dis.. 2008 Dec;31(6):761-8.

 

Dimethylglycine dehydrogenase (DMGDH) is a mitochondrial matrix flavoprotein that catalyses the demethylation of dimethylglycine to form sarcosine, accompanied by the reduction of the covalently bound FAD cofactor. Electron-transfer flavoprotein reoxidizes the reduced flavin and transfers ...

Last Updated: 5 Dec 2008

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Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency.
 

Author(s): B A Binzak, R A Wevers, S H Moolenaar, Y M Lee, W L Hwu, J Poggi-Bach, U F Engelke, H M Hoard, J G Vockley, J Vockley

Journal: Am. J. Hum. Genet.. 2001 Apr;68(4):839-47.

 

Dimethylglycine dehydrogenase (DMGDH) (E.C. number 1.5.99.2) is a mitochondrial matrix enzyme involved in the metabolism of choline, converting dimethylglycine to sarcosine. Sarcosine is then transformed to glycine by sarcosine dehydrogenase (E.C. number 1.5.99.1). Both enzymes use ...

Last Updated: 20 Mar 2001

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Reviews from the PubMed Database

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The terms "Dimethylglycine dehydrogenase deficiency" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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