Diabetes mellitus type 2

Common Name(s)

Diabetes mellitus type 2, Type 2 diabetes

Type 2 diabetes mellitus is a metabolic disease in which a person has high blood sugar or glucose levels. Glucose is the main energy or fuel source for our body’s cells. Insulin helps our body’s cells take in the glucose from our bloodstream. Type 2 diabetes can result because the pancreas cannot produce enough insulin or due to an inability of the body's cells to recognize insulin. Therefore lack of insulin or the inability of cells to recognize insulin results in increased or high blood glucose levels. Early symptoms may include an increased thirst and hunger, weight loss, fatigue, blurred vision, slow-healing sores or increased infections, and darkened areas of skin.

Rates of type 2 diabetes have gone up recently, especially in younger people, as obesity rates have also increased. Other risk factors include fat distributed mainly in the belly, inactivity, family history, race, and age. Uncontrolled blood glucose levels for an extended period of time can cause damage to blood vessels, the kidney, nerves, eyes, feet, skin and mouth, hearing, and greatly increases the risk of cardiovascular problems such as heart disease and heart attack. There's no cure for type 2 diabetes, but you may be able to manage the condition by eating well, exercising and maintaining a healthy weight. If diet and exercise aren't enough to manage your blood sugar well, you also may need diabetes medications or insulin therapy. If you or a family member has been diagnosed with type 2 diabetes, talk with your doctor about treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

Last Updated: 6 Mar 2013

View Details
Logo
Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

Last Updated: 28 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

http://www.diabeteshandsfoundation.org

Last Updated: 6 Mar 2013

View Details
Logo
Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

http://www.tcoyd.org

Last Updated: 28 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes mellitus type 2" returned 1524 free, full-text research articles on human participants. First 3 results:

Use of basal insulin and the associated clinical outcomes among elderly nursing home residents with type 2 diabetes mellitus: a retrospective chart review study.
 

Author(s): Keith L Davis, Wenhui Wei, Juliana L Meyers, Brett S Kilpatrick, Naushira Pandya

Journal:

 

The management of type 2 diabetes mellitus in long-term care (LTC) settings can be complex as a result of age-related complications. Despite guideline recommendations, sliding scale insulin remains commonplace in the LTC setting and data on basal insulin use are lacking.

Last Updated: 3 Nov 2014

Go To URL
Aortic reservoir characteristics and brain structure in people with type 2 diabetes mellitus; a cross sectional study.
 

Author(s): Rachel E D Climie, Velandai Srikanth, Richard Beare, Laura J Keith, James Fell, Justin E Davies, James E Sharman

Journal:

 

Central hemodynamics help to maintain appropriate cerebral and other end-organ perfusion, and may be altered with ageing and type 2 diabetes mellitus (T2DM). We aimed to determine the associations between central hemodynamics and brain structure at rest and during exercise in people ...

Last Updated: 11 Nov 2014

Go To URL
Plasma triglycerides predict ten-years all-cause mortality in outpatients with type 2 diabetes mellitus: a longitudinal observational study.
 

Author(s): Maria-Agata Miselli, Edoardo Dalla Nora, Angelina Passaro, Franco Tomasi, Giovanni Zuliani

Journal:

 

Cardiovascular disease (CVD) is the leading cause of death in type 2 diabetes mellitus (T2DM). American Diabetes Association standards of care set a series of targets recommended for the CVD prevention: blood pressure, LDL and HDL cholesterol (LDL-C and HDL-C), triglycerides and HbA1c ...

Last Updated: 17 Oct 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes mellitus type 2" returned 223 free, full-text review articles on human participants. First 3 results:

Mechanisms in endocrinology: Gut microbiota in patients with type 2 diabetes mellitus.
 

Author(s): Kristine H Allin, Trine Nielsen, Oluf Pedersen

Journal: Eur. J. Endocrinol.. 2015 Apr;172(4):R167-77.

 

Perturbations of the composition and function of the gut microbiota have been associated with metabolic disorders including obesity, insulin resistance and type 2 diabetes. Studies on mice have demonstrated several underlying mechanisms including host signalling through bacterial ...

Last Updated: 28 Feb 2015

Go To URL
Effect of long-term exposure to air pollution on type 2 diabetes mellitus risk: a systemic review and meta-analysis of cohort studies.
 

Author(s): Bin Wang, Donghua Xu, Zhaohai Jing, Dawei Liu, Shengli Yan, Yangang Wang

Journal: Eur. J. Endocrinol.. 2014 Nov;171(5):R173-82.

 

To assess the effect of long-term exposure to air pollution on type 2 diabetes risk, a meta-analysis of prospective cohort studies was performed.

Last Updated: 9 Oct 2014

Go To URL
Therapy of endocrine disease. Effects of chronic use of phosphodiesterase inhibitors on endothelial markers in type 2 diabetes mellitus: a meta-analysis.
 

Author(s): Daniele Santi, Elisa Giannetta, Andrea M Isidori, Cristiana Vitale, Antonio Aversa, Manuela Simoni

Journal: Eur. J. Endocrinol.. 2015 Mar;172(3):R103-14.

 

Diabetes mellitus (DM) is associated with endothelial dysfunction, reducing nitric oxide-dependent vasodilation, and increasing production of pro-inflammatory factors, leading to an increased risk of long-term cardiovascular disease. As the effects of phosphodiesterase 5 inhibitors ...

Last Updated: 9 Feb 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Metabolic Syndrome; Cardiovascular Disease; Diastolic Dysfunction; Fatty Liver

 

Last Updated: 10 Dec 2014

Go to URL
Tele-Diab: Electronic Diary for Patients With Type 2 Diabetes Mellitus
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Insulin Resistance

 

Last Updated: 4 Aug 2011

Go to URL
Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus
 

Status: Not yet recruiting

Condition Summary: Dietary Modification; Diabetes Mellitus Type 2; Insulin Tolerance; Diabetic Blood Glucose Monitoring

 

Last Updated: 28 Jul 2014

Go to URL