Diabetes mellitus type 2

Common Name(s)

Diabetes mellitus type 2, Type 2 diabetes

Type 2 diabetes mellitus is a metabolic disease in which a person has high blood sugar or glucose levels. Glucose is the main energy or fuel source for our body’s cells. Insulin helps our body’s cells take in the glucose from our bloodstream. Type 2 diabetes can result because the pancreas cannot produce enough insulin or due to an inability of the body's cells to recognize insulin. Therefore lack of insulin or the inability of cells to recognize insulin results in increased or high blood glucose levels. Early symptoms may include an increased thirst and hunger, weight loss, fatigue, blurred vision, slow-healing sores or increased infections, and darkened areas of skin.

Rates of type 2 diabetes have gone up recently, especially in younger people, as obesity rates have also increased. Other risk factors include fat distributed mainly in the belly, inactivity, family history, race, and age. Uncontrolled blood glucose levels for an extended period of time can cause damage to blood vessels, the kidney, nerves, eyes, feet, skin and mouth, hearing, and greatly increases the risk of cardiovascular problems such as heart disease and heart attack. There's no cure for type 2 diabetes, but you may be able to manage the condition by eating well, exercising and maintaining a healthy weight. If diet and exercise aren't enough to manage your blood sugar well, you also may need diabetes medications or insulin therapy. If you or a family member has been diagnosed with type 2 diabetes, talk with your doctor about treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

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Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

Last Updated: 6 Mar 2013

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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

Last Updated: 28 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

http://www.diabeteshandsfoundation.org

Last Updated: 6 Mar 2013

View Details
Logo
Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

http://www.tcoyd.org

Last Updated: 28 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes mellitus type 2" returned 2036 free, full-text research articles on human participants. First 3 results:

High Prevalence of Hypovitaminosis D in Postmenopausal Women with Type 2 Diabetes Mellitus.
 

Author(s): Ivan Raška, Mária Rašková, Vít Zikán, Jan Škrha

Journal: Prague Med Rep. 2016 ;117(1):5-17.

 

The link between vitamin D and type 2 diabetes mellitus (T2DM) is intensively studied. This study aims to define the serum concentration of 25-hydroxyvitamin D (25-OH D) and to investigate the relationship between 25-OH D status, glycated hemoglobin (HbA1c) and body composition in ...

Last Updated: 21 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes mellitus type 2" returned 278 free, full-text review articles on human participants. First 3 results:

The Efficacy of Ginseng-Related Therapies in Type 2 Diabetes Mellitus: An Updated Systematic Review and Meta-analysis.
 

Author(s): Qi-Feng Gui, Zhe-Rong Xu, Ke-Ying Xu, Yun-Mei Yang

Journal: Medicine (Baltimore). 2016 Feb;95(6):e2584.

 

Few randomized clinical trials have evaluated the efficacy of ginseng in patients with type 2 diabetes mellitus (T2DM). The current meta-analysis evaluated the ginseng-induced improvement in glucose control and insulin sensitivity in patients with type-2 diabetes or impaired glucose ...

Last Updated: 13 Feb 2016

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Effects of Sitagliptin on Lipid Profiles in Patients With Type 2 Diabetes Mellitus: A Meta-analysis of Randomized Clinical Trials.
 

Author(s): Minhua Fan, Yuelan Li, Shihong Zhang

Journal: Medicine (Baltimore). 2016 Jan;95(2):e2386.

 

Sitagliptin has been reported to improve lipid profiles, but findings from these studies are conflicting. We conducted this meta-analysis to evaluate the effects of sitagliptin on serum lipids in patients with type 2 diabetes mellitus.We made a comprehensive literature search in PubMed, ...

Last Updated: 15 Jan 2016

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Renal Denervation: A Potential Novel Treatment for Type 2 Diabetes Mellitus?
 

Author(s): Tao Pan, Jin-he Guo, Gao-jun Teng

Journal: Medicine (Baltimore). 2015 Nov;94(44):e1932.

 

Type 2 diabetes mellitus (T2DM) is a group of metabolic diseases of multiple etiologies. Although great progress has been made, researchers are still working on the pathogenesis of T2DM and how to best use the treatments available. Aside from several novel pharmacological approaches, ...

Last Updated: 11 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Lixisenatide Efficacy in Diabetes Mellitus Type 2 With Failure of Other GLP-1 Analog
 

Status: Not yet recruiting

Condition Summary: Diabetes Mellitus Type 2

 

Last Updated: 9 May 2016

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Tele-Diab: Electronic Diary for Patients With Type 2 Diabetes Mellitus
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Insulin Resistance

 

Last Updated: 4 Aug 2011

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Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus
 

Status: Not yet recruiting

Condition Summary: Dietary Modification; Diabetes Mellitus Type 2; Insulin Tolerance; Diabetic Blood Glucose Monitoring

 

Last Updated: 28 Jul 2014

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