Diabetes mellitus type 2

Common Name(s)

Diabetes mellitus type 2, Type 2 diabetes

Type 2 diabetes mellitus is a metabolic disease in which a person has high blood sugar or glucose levels. Glucose is the main energy or fuel source for our body’s cells. Insulin helps our body’s cells take in the glucose from our bloodstream. Type 2 diabetes can result because the pancreas cannot produce enough insulin or due to an inability of the body's cells to recognize insulin. Therefore lack of insulin or the inability of cells to recognize insulin results in increased or high blood glucose levels. Early symptoms may include an increased thirst and hunger, weight loss, fatigue, blurred vision, slow-healing sores or increased infections, and darkened areas of skin.

Rates of type 2 diabetes have gone up recently, especially in younger people, as obesity rates have also increased. Other risk factors include fat distributed mainly in the belly, inactivity, family history, race, and age. Uncontrolled blood glucose levels for an extended period of time can cause damage to blood vessels, the kidney, nerves, eyes, feet, skin and mouth, hearing, and greatly increases the risk of cardiovascular problems such as heart disease and heart attack. There's no cure for type 2 diabetes, but you may be able to manage the condition by eating well, exercising and maintaining a healthy weight. If diet and exercise aren't enough to manage your blood sugar well, you also may need diabetes medications or insulin therapy. If you or a family member has been diagnosed with type 2 diabetes, talk with your doctor about treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

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Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

Last Updated: 6 Mar 2013

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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

Last Updated: 28 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

http://www.diabeteshandsfoundation.org

Last Updated: 6 Mar 2013

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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

http://www.tcoyd.org

Last Updated: 28 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes mellitus type 2" returned 1607 free, full-text research articles on human participants. First 3 results:

Effect of transcutaneous electrical nerve stimulation at acupoints on patients with type 2 diabetes mellitus: a randomized controlled trial.
 

Author(s): Wu Zhiyuan, Yang Ming, Jia Jie, Wu Yi, Huang Tiansheng, Li Mingfen, He Zhijie, Guo Zhenzhen, Leung Mason Chin Pang

Journal: J Tradit Chin Med. 2015 Apr;35(2):134-40.

 

To examine whether transcutaneous electric nerve stimulation at acupoints (Acu-TENS) improved the biochemical and physical indices of patients with type 2 diabetes mellitus (T2DM).

Last Updated: 15 May 2015

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Relationship between family functioning and mental health considering the mediating role of resiliency in type 2 diabetes mellitus patients.
 

Author(s): Mostafa Bahremand, Alireza Rai, Mostafa Alikhani, Samira Mohammadi, Karoon Shahebrahimi, Parisa Janjani

Journal:

 

This study was aimed at describing the mediating role of resiliency in the relationship between family functioning and mental health in patients with type 2 diabetes mellitus. This descriptive research was a correlational study. A total of 225 individuals were chosen by simple random ...

Last Updated: 7 May 2015

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Factors associated with dietary diversity score among individuals with type 2 diabetes mellitus.
 

Author(s): Kee Fong Tiew, Yoke Mun Chan, Munn Sann Lye, Seng Cheong Loke

Journal: J Health Popul Nutr. 2014 Dec;32(4):665-76.

 

Studies on diet quality among individuals with type 2 diabetes mellitus (T2DM) are scarce. This crosssectional study aimed to assess the diet quality and to determine its associated factors among individuals with T2DM at the Medical Outpatients Department, Serdang Hospital, Selangor, ...

Last Updated: 21 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes mellitus type 2" returned 239 free, full-text review articles on human participants. First 3 results:

Mechanisms in endocrinology: Gut microbiota in patients with type 2 diabetes mellitus.
 

Author(s): Kristine H Allin, Trine Nielsen, Oluf Pedersen

Journal: Eur. J. Endocrinol.. 2015 Apr;172(4):R167-77.

 

Perturbations of the composition and function of the gut microbiota have been associated with metabolic disorders including obesity, insulin resistance and type 2 diabetes. Studies on mice have demonstrated several underlying mechanisms including host signalling through bacterial ...

Last Updated: 28 Feb 2015

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Association of the vitamin D binding protein polymorphisms with the risk of type 2 diabetes mellitus: a meta-analysis.
 

Author(s): Gaoshuai Wang, Yuqian Li, Linlin Li, Fei Yu, Lingling Cui, Yue Ba, Wenjie Li, Chongjian Wang

Journal:

 

Previous studies on the association between vitamin D binding protein (DBP) polymorphisms and the risk of type 2 diabetes mellitus (T2DM) have produced conflicting results. The purpose of this meta-analysis was to examine whether DBP polymorphisms are associated with the risk of T2DM.

Last Updated: 5 Nov 2014

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Effects of ACEI/ARB in hypertensive patients with type 2 diabetes mellitus: a meta-analysis of randomized controlled studies.
 

Author(s): Guang Hao, Zengwu Wang, Rui Guo, Zuo Chen, Xin Wang, Linfeng Zhang, Wei Li

Journal:

 

The effects of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) on cardiovascular (CV) risk in hypertensive patients with type 2 diabetes mellitus (T2 DM) are uncertain. Our objective was to analyze the effects of ACE/ARBs, on the incidence ...

Last Updated: 3 Nov 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Metabolic Syndrome; Cardiovascular Disease; Diastolic Dysfunction; Fatty Liver

 

Last Updated: 10 Dec 2014

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Tele-Diab: Electronic Diary for Patients With Type 2 Diabetes Mellitus
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Insulin Resistance

 

Last Updated: 4 Aug 2011

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Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus
 

Status: Not yet recruiting

Condition Summary: Dietary Modification; Diabetes Mellitus Type 2; Insulin Tolerance; Diabetic Blood Glucose Monitoring

 

Last Updated: 28 Jul 2014

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