Diabetes mellitus type 2

Common Name(s)

Diabetes mellitus type 2

Type 2 diabetes mellitus is a metabolic disease in which a person has high blood sugar levels that result from either an inability of the pancreas to produce enough insulin or an inability of the body's cells to recognize insulin. Insulin facilitates the uptake of glucose from the bloodstream into the cells. Therefore lack of insulin or the inability of cells to recognize insulin results in increased or high blood glucose levels. This causes increased thirst and hunger, weight loss, fatigue, blurred vision, slow-healing sores or increased infections, and darkened areas of skin. Rates of type 2 diabetes have gone up recently, especially in younger people, as obesity rates have also increased. Other risk factors include fat distributed mainly in the belly, inactivity, family history, race, and age. Uncontrolled blood glucose levels for an extended period of time can cause damage to blood vessels, the kidney, nerves, eyes, feet, skin and mouth, hearing, and greatly increases the risk of cardiovascular problems such as heart disease and heart attack.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

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Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

Last Updated: 6 Mar 2013

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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

Last Updated: 28 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

http://www.diabeteshandsfoundation.org

Last Updated: 6 Mar 2013

View Details
Logo
Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

http://www.tcoyd.org

Last Updated: 28 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes mellitus type 2" returned 1435 free, full-text research articles on human participants. First 3 results:

An exceptional association: ulcerative colitis, amyloidosis and type-2 diabetes mellitus.
 

Author(s): Madiha Mahfoudhi, Mondher Ounissi, Anis Hariz, Khaoula Ben Abdelghani, Karima Boubaker, Sami Turki, Adel Kheder

Journal: Tunis Med. 2014 Feb;92(2):169.

 

Last Updated: 18 Jun 2014

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A novel method for studying the temporal relationship between type 2 diabetes mellitus and cancer using the electronic medical record.
 

Author(s): Adedayo A Onitilo, Rachel V Stankowski, Richard L Berg, Jessica M Engel, Gail M Williams, Suhail A Doi

Journal:

 

We developed an algorithm for the identification of patients with type 2 diabetes and ascertainment of the date of diabetes onset for examination of the temporal relationship between diabetes and cancer using data in the electronic medical record (EMR).

Last Updated: 4 Jun 2014

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Integrative analysis of the transcriptome profiles observed in type 1, type 2 and gestational diabetes mellitus reveals the role of inflammation.
 

Author(s): Adriane F Evangelista, Cristhianna V A Collares, Danilo J Xavier, Claudia Macedo, Fernanda S Manoel-Caetano, Diane M Rassi, Maria C Foss-Freitas, Milton C Foss, Elza T Sakamoto-Hojo, Catherine Nguyen, Denis Puthier, Geraldo A Passos, Eduardo A Donadi

Journal:

 

Type 1 diabetes (T1D) is an autoimmune disease, while type 2 (T2D) and gestational diabetes (GDM) are considered metabolic disturbances. In a previous study evaluating the transcript profiling of peripheral mononuclear blood cells obtained from T1D, T2D and GDM patients we showed ...

Last Updated: 24 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes mellitus type 2" returned 230 free, full-text review articles on human participants. First 3 results:

Association between eNOS 4b/a polymorphism and the risk of diabetic retinopathy in type 2 diabetes mellitus: a meta-analysis.
 

Author(s): Ze-jun Ma, Rui Chen, Hui-Zhu Ren, Xin Guo, Jun Guo, Li-ming Chen

Journal: J Diabetes Res. 2014 ;2014():549747.

 

Many studies have assessed the association between eNOS-4b/a polymorphism and the risk of diabetic retinopathy (DR) among type 2 diabetic subjects. However, the results are inconsistent. In order to derive a more precise estimation of the association, a meta-analysis was conducted. ...

Last Updated: 4 Jun 2014

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Incretin treatment and risk of pancreatitis in patients with type 2 diabetes mellitus: systematic review and meta-analysis of randomised and non-randomised studies.
 

Author(s): Ling Li, Jiantong Shen, Malgorzata M Bala, Jason W Busse, Shanil Ebrahim, Per Olav Vandvik, Lorena P Rios, German Malaga, Evelyn Wong, Zahra Sohani, Gordon H Guyatt, Xin Sun

Journal:

 

To investigate the risk of pancreatitis associated with the use of incretin-based treatments in patients with type 2 diabetes mellitus.

Last Updated: 16 Apr 2014

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The role of MIF in type 1 and type 2 diabetes mellitus.
 

Author(s): Yuriko I Sánchez-Zamora, Miriam Rodriguez-Sosa

Journal: J Diabetes Res. 2014 ;2014():804519.

 

Autoimmunity and chronic low-grade inflammation are hallmarks of diabetes mellitus type one (T1DM) and type two (T2DM), respectively. Both processes are orchestrated by inflammatory cytokines, including the macrophage migration inhibitory factor (MIF). To date, MIF has been implicated ...

Last Updated: 14 Feb 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Metabolic Syndrome; Cardiovascular Disease; Diastolic Dysfunction; Fatty Liver

 

Last Updated: 28 Nov 2013

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Vitamin D Supplementation in Patients With Diabetes Mellitus Type 2
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Vitamin D Deficiency

 

Last Updated: 4 Dec 2012

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Tele-Diab: Electronic Diary for Patients With Type 2 Diabetes Mellitus
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Insulin Resistance

 

Last Updated: 4 Aug 2011

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