Diabetes mellitus type 2

Common Name(s)

Diabetes mellitus type 2, Type 2 diabetes

Type 2 diabetes mellitus is a metabolic disease in which a person has high blood sugar or glucose levels. Glucose is the main energy or fuel source for our body’s cells. Insulin helps our body’s cells take in the glucose from our bloodstream. Type 2 diabetes can result because the pancreas cannot produce enough insulin or due to an inability of the body's cells to recognize insulin. Therefore lack of insulin or the inability of cells to recognize insulin results in increased or high blood glucose levels. Early symptoms may include an increased thirst and hunger, weight loss, fatigue, blurred vision, slow-healing sores or increased infections, and darkened areas of skin.

Rates of type 2 diabetes have gone up recently, especially in younger people, as obesity rates have also increased. Other risk factors include fat distributed mainly in the belly, inactivity, family history, race, and age. Uncontrolled blood glucose levels for an extended period of time can cause damage to blood vessels, the kidney, nerves, eyes, feet, skin and mouth, hearing, and greatly increases the risk of cardiovascular problems such as heart disease and heart attack. There's no cure for type 2 diabetes, but you may be able to manage the condition by eating well, exercising and maintaining a healthy weight. If diet and exercise aren't enough to manage your blood sugar well, you also may need diabetes medications or insulin therapy. If you or a family member has been diagnosed with type 2 diabetes, talk with your doctor about treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

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Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

Last Updated: 6 Mar 2013

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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

Last Updated: 28 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

http://www.diabeteshandsfoundation.org

Last Updated: 6 Mar 2013

View Details
Logo
Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

http://www.tcoyd.org

Last Updated: 28 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes mellitus type 2" returned 2228 free, full-text research articles on human participants. First 3 results:

A Randomized controlled trial of the effect of yoga and peer support on glycaemic outcomes in women with type 2 diabetes mellitus: a feasibility study.
 

Author(s): Aswathy Sreedevi, Unnikrishnan Ambika Gopalakrishnan, Sundaram Karimassery Ramaiyer, Leelamoni Kamalamma

Journal:

 

Type two diabetes is a complex and demanding chronic disease and its impact in a state (Kerala) which leads India in terms of the number of people with Diabetes is profound. Though the male to female ratio among the people with diabetes is roughly equal, women are uniquely and more ...

Last Updated: 8 Feb 2017

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Quality of sleep and risk for obstructive sleep apnoea in ambulant individuals with type 2 diabetes mellitus at a tertiary referral hospital in Kenya: a cross-sectional, comparative study.
 

Author(s): Sairabanu Mohammed Rashid Sokwalla, Mark David Joshi, Erastus Olonde Amayo, Kirtida Acharya, Jared Ongechi Mecha, Kenneth Kipyegon Mutai

Journal:

 

Sleep disorders are common and associated with multiple metabolic and psychological derangements. Obstructive sleep apnoea (OSA) is among the most common sleep disorders and an inter-relationship between OSA, insulin resistance, obesity, type 2 diabetes (T2DM) and cardiovascular diseases ...

Last Updated: 7 Feb 2017

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Awareness of diabetic foot disease amongst patients with type 2 diabetes mellitus attending the chronic outpatients department at a regional hospital in Durban, South Africa.
 

Author(s): Thea T Goie, Mergan Naidoo

Journal:

 

Diabetic foot disease (DFD) is a major challenge for the healthcare system, with enormous economic consequences for people living with diabetes, their families, and society, affecting both quality of life and quality of care. The study aim was to assess the level of awareness of DFD ...

Last Updated: 3 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes mellitus type 2" returned 304 free, full-text review articles on human participants. First 3 results:

Cell-Derived Microparticles in Patients with Type 2 Diabetes Mellitus: a Systematic Review and Meta-Analysis.
 

Author(s): Sheyu Li, Jia Wei, Chenghui Zhang, Xiaodan Li, Wentong Meng, Xianming Mo, Qianying Zhang, Qilin Liu, Kaiyun Ren, Rong Du, Haoming Tian, Jianwei Li

Journal: Cell. Physiol. Biochem.. 2016 ;39(6):2439-2450.

 

The aim of this study was to assess the association between circulating cell-derived microparticles (MPs) and type 2 diabetes mellitus (T2DM).

Last Updated: 10 Nov 2016

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Impact of the conversation map tools in patients with type 2 diabetes mellitus: A PRISMA-compliant meta-analysis of randomized controlled trials.
 

Author(s): Qing Yang, Ping Fang

Journal: Medicine (Baltimore). 2016 Oct;95(40):e4664.

 

Diabetes is one of the leading causes of morbidity and mortality worldwide, and type 2 diabetes is the most common type accounting for 90% of all diabetes cases. Health education is considered as the first choice to control blood glucose levels. We conducted a meta-analysis to assess ...

Last Updated: 17 Oct 2016

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MANAGEMENT OF ENDOCRINE DISEASE: The effect of vitamin D supplementation on glycaemic control in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.
 

Author(s): Yvonne H M Krul-Poel, Marieke M Ter Wee, Paul Lips, Suat Simsek

Journal: Eur. J. Endocrinol.. 2017 Jan;176(1):R1-R14.

 

Epidemiologic studies suggest that vitamin D status plays a role in glycaemic control in patients with type 2 diabetes. However, intervention studies yielded inconsistent results. The aim of this study is to systematically review the effect of vitamin D supplementation on glycaemic ...

Last Updated: 3 Aug 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Lixisenatide Efficacy in Diabetes Mellitus Type 2 With Failure of Other GLP-1 Analog
 

Status: Not yet recruiting

Condition Summary: Diabetes Mellitus Type 2

 

Last Updated: 9 May 2016

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Adipose Tissue Imaging in Type 2 Diabetes
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2

 

Last Updated: 6 Apr 2016

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Last Updated: 26 Apr 2016

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