Diabetes mellitus type 2

Common Name(s)

Diabetes mellitus type 2, Type 2 diabetes

Type 2 diabetes mellitus is a metabolic disease in which a person has high blood sugar or glucose levels. Glucose is the main energy or fuel source for our body’s cells. Insulin helps our body’s cells take in the glucose from our bloodstream. Type 2 diabetes can result because the pancreas cannot produce enough insulin or due to an inability of the body's cells to recognize insulin. Therefore lack of insulin or the inability of cells to recognize insulin results in increased or high blood glucose levels. Early symptoms may include an increased thirst and hunger, weight loss, fatigue, blurred vision, slow-healing sores or increased infections, and darkened areas of skin.

Rates of type 2 diabetes have gone up recently, especially in younger people, as obesity rates have also increased. Other risk factors include fat distributed mainly in the belly, inactivity, family history, race, and age. Uncontrolled blood glucose levels for an extended period of time can cause damage to blood vessels, the kidney, nerves, eyes, feet, skin and mouth, hearing, and greatly increases the risk of cardiovascular problems such as heart disease and heart attack. There's no cure for type 2 diabetes, but you may be able to manage the condition by eating well, exercising and maintaining a healthy weight. If diet and exercise aren't enough to manage your blood sugar well, you also may need diabetes medications or insulin therapy. If you or a family member has been diagnosed with type 2 diabetes, talk with your doctor about treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

Last Updated: 6 Mar 2013

View Details
Logo
Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

Last Updated: 28 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 2" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

http://www.diabeteshandsfoundation.org

Last Updated: 6 Mar 2013

View Details
Logo
Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

http://www.tcoyd.org

Last Updated: 28 Mar 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes mellitus type 2" returned 1834 free, full-text research articles on human participants. First 3 results:

The Prevalence of Type 2 Diabetes Mellitus in a Wisconsin Hmong Patient Population.
 

Author(s): Kevin K Thao, Brian Arndt, Aman Tandias, Lawrence Hanrahan

Journal: WMJ. 2015 Oct;114(5):190-5.

 

Wisconsin's largest Asian population, the Hmong, may be at high risk for type 2 diabetes. However, there are few population-based studies investigating the prevalence of diabetes in this population. This study compared the prevalence of diabetes between Hmong and non-Hispanic white ...

Last Updated: 1 Jan 2016

Go To URL
Characteristics of blood glucose excursions in type 2 diabetes mellitus patients with three different Traditional Chinese Medicine syndromes.
 

Author(s): Hongyan Zhang, Jian Zhou, Lei Zhang, Jianhui Ma, Yongning Sun, Yuwu Zhao

Journal: J Tradit Chin Med. 2015 Oct;35(5):537-45.

 

To explore the characteristics of blood glucose excursions of type 2 diabetes mellitus patients with three different Traditional Chinese Medicine (TCM) syndromes.

Last Updated: 20 Nov 2015

Go To URL
Cardiovascular Risk Factors Increase the Risks of Diabetic Peripheral Neuropathy in Patients With Type 2 Diabetes Mellitus: The Taiwan Diabetes Study.
 

Author(s): Chun-Pai Yang, Cheng-Chieh Lin, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, Kai-Lin Hwang, Sing-Yu Yang, Hsuan-Ju Chen, Tsai-Chung Li

Journal: Medicine (Baltimore). 2015 Oct;94(42):e1783.

 

This study aimed to examine whether poor glycemic control, measured by glycated hemoglobin A1C (HbA1c) and other cardiovascular risk factors, can predict diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (DM).Patients aged ≥30 years with type 2 DM, enrolled ...

Last Updated: 27 Oct 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes mellitus type 2" returned 264 free, full-text review articles on human participants. First 3 results:

Efficacy of inhibition of IL-1 in patients with rheumatoid arthritis and type 2 diabetes mellitus: two case reports and review of the literature.
 

Author(s): Piero Ruscitti, Paola Cipriani, Luca Cantarini, Vasiliki Liakouli, Antonio Vitale, Francesco Carubbi, Onorina Berardicurti, Mauro Galeazzi, Marco Valenti, Roberto Giacomelli

Journal:

 

Rheumatoid arthritis is an autoimmune arthritis in which two inflammatory cytokines, tumor necrosis factor-α and interleukin-1β, play a critical role in the induction and progression of the disease. Several reports and data from registries have discussed the association between ...

Last Updated: 6 Jun 2015

Go To URL
Association of type 2 diabetes mellitus and the risk of colorectal cancer: A meta-analysis and systematic review.
 

Author(s): Salman Yousuf Guraya

Journal: World J. Gastroenterol.. 2015 May;21(19):6026-31.

 

To provide a quantitative assessment of the association between type 2 diabetes mellitus (T2DM) and the risk of colorectal cancer (CRC).

Last Updated: 28 May 2015

Go To URL
Effect of Intensive Versus Standard Blood Glucose Control in Patients With Type 2 Diabetes Mellitus in Different Regions of the World: Systematic Review and Meta-analysis of Randomized Controlled Trials.
 

Author(s): Partha Sardar, Jacob A Udell, Saurav Chatterjee, Sameer Bansilal, Debabrata Mukherjee, Michael E Farkouh

Journal:

 

Regional variation in type 2 diabetes mellitus care may affect outcomes in patients treated with intensive versus standard blood glucose control. We sought to evaluate these differences between North America and the rest of the world.

Last Updated: 6 May 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Tele-Diab: Electronic Diary for Patients With Type 2 Diabetes Mellitus
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Insulin Resistance

 

Last Updated: 4 Aug 2011

Go to URL
Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus
 

Status: Not yet recruiting

Condition Summary: Dietary Modification; Diabetes Mellitus Type 2; Insulin Tolerance; Diabetic Blood Glucose Monitoring

 

Last Updated: 28 Jul 2014

Go to URL
Outpatient Discharge Therapy With Saxagliptin+MetforminXR vs GlipizideXL for Type 2 Diabetes With Severe Hyperglycemia
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 2; Severe Hyperglycemia - Blood Glucose Level >300mg/dl.

 

Last Updated: 15 Apr 2011

Go to URL