Crigler-Najjar syndrome

Common Name(s)

Crigler-Najjar syndrome

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Crigler-Najjar syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Crigler-Najjar syndrome" returned 43 free, full-text research articles on human participants. First 3 results:

Acute cholangitis in an old patient with Crigler-Najjar syndrome type II - a case report.
 

Author(s): Samuel Raimundo Fernandes, Carlos Miguel Moura, Beatriz Rodrigues, Luís Araújo Correia, Helena Cortez-Pinto, José Velosa

Journal:

 

Crigler-Najjar syndrome (CN) is a very rare genetic disorder characterized by an inability to conjugate bilirubin. Contrary to CN type I, patients with CN II exhibit residual capacity to conjugate bilirubin and may present a normal life expectancy.

Last Updated: 12 Mar 2016

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Two Different UGT1A1 Mutations causing Crigler-Najjar Syndrome types I and II in an Iranian Family.
 

Author(s): Yoshihiro Maruo, Mahdiyeh Behnam, Shinichi Ikushiro, Sayuri Nakahara, Narges Nouri, Mansour Salehi

Journal: J Gastrointestin Liver Dis. 2015 Dec;24(4):523-6.

 

Crigler-Najjar syndrome type I (CN-1) and type II (CN-2) are rare hereditary unconjugated hyperbilirubinemia disorders. However, there have been no reports regarding the co-existence of CN-1 and CN-2 in one family. We experienced a case of an Iranian family that included members with ...

Last Updated: 23 Dec 2015

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X-linked ichthyosis and Crigler-Najjar syndrome I: Coexistence in a male patient with two copy number variable regions of 2q37.1 and Xp22.3.
 

Author(s): Jinli Bai, Yujin Qu, Yanyan Cao, Yan Li, Wenhui Zhang, Yuwei Jin, Hong Wang, Fang Song

Journal: Mol Med Rep. 2016 Feb;13(2):1135-40.

 

X-linked ichthyosis (XLI) is an X-linked recessive skin disorder generally restricted to males, which arises from mutations in the steroid sulfatase (STS) gene located on Xp22.3. Crigler-Najjar syndrome (CN-I) is a rare autosomal recessive disease caused by the homozygous or compound ...

Last Updated: 10 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Crigler-Najjar syndrome" returned 2 free, full-text review articles on human participants. First 3 results:

Pregnancy outcome in maternal Crigler-Najjar syndrome type II: a case report and systematic review of the literature.
 

Author(s): V Passuello, A G Puhl, S Wirth, E Steiner, C Skala, H Koelbl, N Kohlschmidt

Journal: Fetal. Diagn. Ther.. 2009 ;26(3):121-6.

 

To report a case of maternal Crigler-Najjar syndrome (CNS) type II in pregnancy, systematically review the literature for similar case reports, and to evaluate whether pregnancy is safe in patients with the disease. Data sources included the PubMed and up to date databases.

Last Updated: 9 Dec 2009

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Liver cell transplantation for Crigler-Najjar syndrome type I: update and perspectives.
 

Author(s): Philippe-A Lysy, Mustapha Najimi, Xavier Stephenne, Annick Bourgois, Francoise Smets, Etienne-M Sokal

Journal: World J. Gastroenterol.. 2008 Jun;14(22):3464-70.

 

Liver cell transplantation is an attractive technique to treat liver-based inborn errors of metabolism. The feasibility and efficacy of the procedure has been demonstrated, leading to medium term partial metabolic control of various diseases. Crigler-Najjar is the paradigm of such ...

Last Updated: 20 Jun 2008

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Immunity Against AAV in Crigler Najjar Patient
 

Status: Recruiting

Condition Summary: Crigler Najjar Syndrome

 

Last Updated: 17 Aug 2016

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