Corneal epithelial dystrophy

Common Name(s)

Corneal epithelial dystrophy

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Corneal epithelial dystrophy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Corneal epithelial dystrophy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Corneal epithelial dystrophy" returned 11 free, full-text research articles on human participants. First 3 results:

Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy.
 

Author(s): Edwin H A Allen, David G Courtney, Sarah D Atkinson, Johnny E Moore, Laura Mairs, Ebbe Toftgaard Poulsen, Davide Schiroli, Eleonora Maurizi, Christian Cole, Robyn P Hickerson, John James, Helen Murgatroyd, Frances J D Smith, Carrie MacEwen, Jan J Enghild, M Andrew Nesbit, Deena M Leslie Pedrioli, W H Irwin McLean, C B Tara Moore

Journal: Hum. Mol. Genet.. 2016 Mar;25(6):1176-91.

 

Meesmann epithelial corneal dystrophy (MECD) is a rare autosomal dominant disorder caused by dominant-negative mutations within the KRT3 or KRT12 genes, which encode the cytoskeletal protein keratins K3 and K12, respectively. To investigate the pathomechanism of this disease, we generated ...

Last Updated: 24 Feb 2016

Go To URL
Corneal nerve architecture in a donor with unilateral epithelial basement membrane dystrophy.
 

Author(s): Jiucheng He, Haydee E P Bazan

Journal: Ophthalmic Res.. 2013 ;49(4):185-91.

 

Epithelial basement membrane dystrophy (EBMD) is by far the most common corneal dystrophy. In this study, we used a newly developed method of immunofluorescence staining and imaging to study the entire corneal nerve architecture of a donor with unilateral EBMD.

Last Updated: 21 May 2013

Go To URL
Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy.
 

Author(s): Edwin H A Allen, Sarah D Atkinson, Haihui Liao, Jonathan E Moore, Deena M Leslie Pedrioli, Frances J D Smith, William H Irwin McLean, C B Tara Moore

Journal:

 

To identify an allele-specific short interfering RNA (siRNA), against the common KRT12 mutation Arg135Thr in Meesmann epithelial corneal dystrophy (MECD) as a personalized approach to treatment.

Last Updated: 18 Jan 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Corneal epithelial dystrophy" returned 0 free, full-text review articles on human participants.

 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic Keratectomy
 

Status: Recruiting

Condition Summary: Corneal Dystrophy, Epithelial Basement Membrane; Epithelial Recurrent Erosion Dystrophy; Corneal Erosions

 

Last Updated: 27 Oct 2015

Go to URL
Optimizing the Ocular Surface Prior to Cataract Surgery
 

Status: Recruiting

Condition Summary: Corneal Dystrophy, Epithelial Basement Membrane

 

Last Updated: 31 Aug 2016

Go to URL