Colorectal cancer 1

Common Name(s)

Colorectal cancer 1

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Colorectal cancer 1" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Colorectal cancer 1" returned 404 free, full-text research articles on human participants. First 3 results:

Long Non-Coding RNA ucoo2kmd.1 Regulates CD44-Dependent Cell Growth by Competing for miR-211-3p in Colorectal Cancer.
 

Author(s): Xiaoli Wu, Xixi He, Shi Li, Xiaoqun Xu, Xiangjian Chen, Hua Zhu

Journal:

 

In addition to protein-coding genes, the human genome makes a large amount of noncoding RNAs. Long non-coding RNAs (lncRNAs) have been described as the largest subclass of the non-coding transcriptome in human noncoding RNAs. In recent years, lncRNAs have been considered to be the ...

Last Updated: 15 Mar 2016

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A randomized, placebo-controlled, phase 1/2 study of tivantinib (ARQ 197) in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with wild-type KRAS who have received first-line systemic therapy.
 

Author(s): Cathy Eng, Alberto Bessudo, Lowell L Hart, Aleksey Severtsev, Oleg Gladkov, Lothar Müller, Mikhail V Kopp, Vladimir Vladimirov, Robert Langdon, Bogdan Kotiv, Sandro Barni, Ching Hsu, Ellen Bolotin, Reinhard von Roemeling, Brian Schwartz, Johanna C Bendell

Journal: Int. J. Cancer. 2016 Jul;139(1):177-86.

 

Cetuximab in combination with an irinotecan-containing regimen is a standard treatment in patients with KRAS wild-type (KRAS WT), metastatic colorectal cancer (mCRC). We investigated the addition of the oral MET inhibitor tivantinib to cetuximab + irinotecan (CETIRI) based on ...

Last Updated: 15 Apr 2016

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Blocking heme oxygenase-1 by zinc protoporphyrin reduces tumor hypoxia-mediated VEGF release and inhibits tumor angiogenesis as a potential therapeutic agent against colorectal cancer.
 

Author(s): Chun-Chia Cheng, Siao-Syun Guan, Hao-Jhih Yang, Chun-Chao Chang, Tsai-Yueh Luo, Jungshan Chang, Ai-Sheng Ho

Journal:

 

Hypoxia in tumor niche is one of important factors to start regeneration of blood vessels, leading to increase survival, proliferation, and invasion in cancer cells. Under hypoxia microenvironment, furthermore, steadily increased hypoxia-inducible factor -1α (HIF-1α) is observed, ...

Last Updated: 29 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Colorectal cancer 1" returned 4 free, full-text review articles on human participants. First 3 results:

Prognostic and clinical significance of syndecan-1 in colorectal cancer: a meta-analysis.
 

Author(s): Hao-Tang Wei, Er-Na Guo, Bao-Guo Dong, Li-Sheng Chen

Journal:

 

Syndecan-1 plays a vital role in the suppression, transformation, and migration of several cancer types, including colorectal cancer (CRC). However, the prognostic and clinical significance of syndecan-1 in CRC remains conflicting. Therefore, we performed a meta-analysis to clarify ...

Last Updated: 31 Oct 2015

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STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer.
 

Author(s): Andrew V Nguyen, Yuan-Yuan Wu, Elaine Y Lin

Journal: World J. Gastroenterol.. 2014 Aug;20(30):10279-87.

 

Accumulated evidences have demonstrated that signal transducer and activator of transcription 3 (STAT3) is a critical link between inflammation and cancer. Multiple studies have indicated that persistent activation of STAT3 in epithelial/tumor cells in inflammation-associated colorectal ...

Last Updated: 18 Aug 2014

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Antineoplastic effects of 1,25(OH)2D3 and its analogs in breast, prostate and colorectal cancer.
 

Author(s): Carlien Leyssens, Lieve Verlinden, Annemieke Verstuyf

Journal:

 

The active form of vitamin D3, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), is mostly known for its importance in the maintenance of calcium and phosphate homeostasis. However, next to its classical effects on bone, kidney and intestine, 1,25(OH)2D3 also exerts antineoplastic effects on ...

Last Updated: 25 Mar 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

To Determine the MTD and to Evaluate the Safety, Efficacy and PK Profiles of TSB-9-W1 in Pre-treated Patients With mCRC.
 

Status: Not yet recruiting

Condition Summary: Metastatic Colorectal Cancer

 

Last Updated: 22 Apr 2016

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Last Updated: 14 Oct 2016

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Colorectal Cancer Detected by 1H-NMR Spectroscopy
 

Status: Recruiting

Condition Summary: Colorectal Cancer

 

Last Updated: 16 Feb 2015

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