Colorectal cancer 1

Common Name(s)

Colorectal cancer 1

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Colorectal cancer 1" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Colorectal cancer 1" returned 372 free, full-text research articles on human participants. First 3 results:

Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to Chromosome 5q31.1: A Post-GWAS Study.
 

Author(s): Juntao Ke, Jiao Lou, Xueqin Chen, Jiaoyuan Li, Cheng Liu, Yajie Gong, Yang Yang, Ying Zhu, Yi Zhang, Jing Gong

Journal:

 

Large-scale genome-wide association studies (GWAS) have established chromosome 5q31.1 as a susceptibility locus for colorectal cancer (CRC), which was still lack of causal genetic variants. We searched potentially regulatory single nucleotide polymorphisms (SNPs) in the overlap region ...

Last Updated: 19 Sep 2015

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Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer.
 

Author(s): Johanna C Bendell, Lee S Rosen, Robert J Mayer, Jonathan W Goldman, Jeffrey R Infante, Fabio Benedetti, Donghu Lin, Hirokazu Mizuguchi, Christopher Zergebel, Manish R Patel

Journal: Cancer Chemother. Pharmacol.. 2015 Nov;76(5):925-32.

 

To evaluate safety of TAS-102 administered twice daily (bid) on days 1-5 and 8-12 of a 4-week cycle, confirm feasibility of the Japanese recommended dose (RD), 35 mg/m(2), in Western patients with metastatic colorectal cancer (mCRC) refractory to standard chemotherapies, and describe ...

Last Updated: 21 Oct 2015

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Study protocol of the TRICOLORE trial: a randomized phase III study of oxaliplatin-based chemotherapy versus combination chemotherapy with S-1, irinotecan, and bevacizumab as first-line therapy for metastatic colorectal cancer.
 

Author(s): Yoshito Komatsu, Chikashi Ishioka, Ken Shimada, Yasuhide Yamada, Makio Gamoh, Atsushi Sato, Tatsuro Yamaguchi, Satoshi Yuki, Satoshi Morita, Shin Takahashi, Rei Goto, Minoru Kurihara

Journal:

 

Metastatic colorectal cancer carries a poor prognosis and cannot be cured by currently available therapy. Chemotherapy designed to prolong survival and improve the quality of life (QOL) of patients is the mainstay of treatment. Standard regimens of FOLFOX/bevacizumab and CapeOX/bevacizumab ...

Last Updated: 10 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Colorectal cancer 1" returned 3 free, full-text review articles on human participants. First 3 results:

STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer.
 

Author(s): Andrew V Nguyen, Yuan-Yuan Wu, Elaine Y Lin

Journal: World J. Gastroenterol.. 2014 Aug;20(30):10279-87.

 

Accumulated evidences have demonstrated that signal transducer and activator of transcription 3 (STAT3) is a critical link between inflammation and cancer. Multiple studies have indicated that persistent activation of STAT3 in epithelial/tumor cells in inflammation-associated colorectal ...

Last Updated: 18 Aug 2014

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Antineoplastic effects of 1,25(OH)2D3 and its analogs in breast, prostate and colorectal cancer.
 

Author(s): Carlien Leyssens, Lieve Verlinden, Annemieke Verstuyf

Journal:

 

The active form of vitamin D3, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), is mostly known for its importance in the maintenance of calcium and phosphate homeostasis. However, next to its classical effects on bone, kidney and intestine, 1,25(OH)2D3 also exerts antineoplastic effects on ...

Last Updated: 25 Mar 2013

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Molecular staging of colorectal cancer in African-American and Caucasian patients using phenotypic expression of p53, Bcl-2, MUC-1 AND p27(kip-1).
 

Author(s): William E Grizzle, Upender Manne, Heide L Weiss, Nirag Jhala, Lynya Talley

Journal: Int. J. Cancer. 2002 Feb;97(4):403-9.

 

The gold standard for clinical outcome of most cancers has been the clinical and pathologic staging of the tumors after surgery. For colorectal cancer (CRC), nodal involvement at the time the primary tumor is resected has been the most reliable indicator of clinical outcome; however, ...

Last Updated: 21 Jan 2002

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 1 Sep 2010

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Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK1/2/3, ROS1, or ALK Gene Rearrangements (Fusions)
 

Status: Recruiting

Condition Summary: Breast Cancer; Cholangiocarcinoma; Colorectal Cancer; Head and Neck Neoplasms; Lymphoma, Large-Cell, Anaplastic; Melanoma; Neuroendocrine Tumors; Non-Small Cell Lung Cancer; Ovarian Cancer; Pancreatic Cancer; Papillary Thyroid Cancer; Primary Brain Tumors; Renal Cell Carcinoma; Sarcomas; Salivary Gland Cancers; Adult Solid Tumor

 

Last Updated: 16 May 2016

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To Determine the MTD and to Evaluate the Safety, Efficacy and PK Profiles of TSB-9-W1 in Pre-treated Patients With mCRC.
 

Status: Not yet recruiting

Condition Summary: Metastatic Colorectal Cancer

 

Last Updated: 22 Apr 2016

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