Chronic obstructive pulmonary disease

Common Name(s)

Chronic obstructive pulmonary disease, COPD

Chronic obstructive pulmonary disease (COPD) is a progressive disease that makes breathing difficult. COPD is a general term describing several progressive lung diseases including emphysema, chronic bronchitis, refractory (non-reversible) asthma, and some forms of bronchiectasis. COPD is usually symptom free at first; but as the lung damage increases, symptoms begin to appear and then worsen over time. Symptoms of COPD may include coughing that produces large amounts of mucus, wheezing, shortness of breath, and chest tightness. COPD is caused by long-term exposure to lung irritants such as cigarette smoke and pollutants as well as genetic factors, including alpha 1 antitrypsin deficiency.

With COPD, less air flows in and out of the airways because of one or more of the following: the airways and air sacs of the lungs lose their elastic quality, the walls between many of the air sacs are destroyed, the walls of the airways become thick and inflamed, and/or the airways make more mucus than usual, which can clog them. COPD may be diagnosed using a noninvasive breathing test called spirometry. Spirometry can detect COPD before symptoms begin, and your doctor may advise you to be screened regularly for COPD if you have a history of smoking, exposure to toxins, fumes or pollutants or have a genetic predisposition to or family history of COPD. Your physician may order other tests to rule out other lung conditions and to determine the best treatment for your stage of COPD. Treatment includes medications and lung therapy. Surgery is sometimes necessary for those with severe emphysema. Although there is currently no cure for COPD, treatments and lifestyle changes can help patients feel better, stay more active, and slow the progress of the disease. If you or a family member has been diagnosed with COPD, talk with your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic obstructive pulmonary disease" for support, advocacy or research.

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COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

Last Updated: 25 Mar 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic obstructive pulmonary disease" for support, advocacy or research.

Logo
COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

http://www.copdfoundation.org

Last Updated: 25 Mar 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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General Support Organizations

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General Resources

COPD Research Registry

The COPD Research Registry is a confidential database of individuals diagnosed with COPD or at risk of developing COPD who have consented to be contacted for participation in COPD research studies and clinical trials.

Uploaded By: COPD Foundation

Updated 21 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic obstructive pulmonary disease" returned 3471 free, full-text research articles on human participants. First 3 results:

Median regression spline modeling of longitudinal FEV1 measurements in cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) patients.
 

Author(s): Douglas J Conrad, Barbara A Bailey, Jon A Hardie, Per S Bakke, Tomas M L Eagan, Bernt B Aarli

Journal:

 

Clinical phenotyping, therapeutic investigations as well as genomic, airway secretion metabolomic and metagenomic investigations can benefit from robust, nonlinear modeling of FEV1 in individual subjects. We demonstrate the utility of measuring FEV1 dynamics in representative cystic ...

Last Updated: 31 Dec 1969

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The relationship of depression in asthma-chronic obstructive pulmonary disease overlap syndrome.
 

Author(s): Jun-Jun Yeh, Cheng-Li Lin, Wu-Huei Hsu, Chia-Hung Kao

Journal:

 

To clarify the relationship between asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) and depression.

Last Updated: 31 Dec 1969

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Assessment of automated analysis of portable oximetry as a screening test for moderate-to-severe sleep apnea in patients with chronic obstructive pulmonary disease.
 

Author(s): Ana M Andrés-Blanco, Daniel Álvarez, Andrea Crespo, C Ainhoa Arroyo, Ana Cerezo-Hernández, Gonzalo C Gutiérrez-Tobal, Roberto Hornero, Félix Del Campo

Journal:

 

The coexistence of obstructive sleep apnea syndrome (OSAS) and chronic obstructive pulmonary disease (COPD) leads to increased morbidity and mortality. The development of home-based screening tests is essential to expedite diagnosis. Nevertheless, there is still very limited evidence ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic obstructive pulmonary disease" returned 685 free, full-text review articles on human participants. First 3 results:

Major adverse cardiac events and mortality in chronic obstructive pulmonary disease following percutaneous coronary intervention: a systematic review and meta-analysis.
 

Author(s): Pravesh Kumar Bundhun, Chakshu Gupta, Guang Ma Xu

Journal:

 

We aimed to systematically compare Major Adverse Cardiac Events (MACEs) and mortality following Percutaneous Coronary Intervention (PCI) in patients with and without Chronic Obstructive Pulmonary Diseases (COPD) through a meta-analysis.

Last Updated: 31 Dec 1969

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Telehealth Interventions to Support Self-Management of Long-Term Conditions: A Systematic Metareview of Diabetes, Heart Failure, Asthma, Chronic Obstructive Pulmonary Disease, and Cancer.
 

Author(s): Peter Hanlon, Luke Daines, Christine Campbell, Brian McKinstry, David Weller, Hilary Pinnock

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Self-management support is one mechanism by which telehealth interventions have been proposed to facilitate management of long-term conditions.

Last Updated: 31 Dec 1969

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Prevalence of comorbidities in chronic obstructive pulmonary disease patients: A meta-analysis.
 

Author(s): Hong-Lei Yin, Shi-Qi Yin, Qing-Yan Lin, Ying Xu, Hong-Wei Xu, Tao Liu

Journal: Medicine (Baltimore). 2017 May;96(19):e6836.

 

This study compares the prevalence rates of comorbidities between chronic obstructive pulmonary disease (COPD) and non-COPD control patients reported in literature.

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Active for Life: Chronic Obstructive Pulmonary Disease
 

Status: Recruiting

Condition Summary: Chronic Obstructive Pulmonary Disease

 

Last Updated: 17 Aug 2017

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Imaging of Apoptosis in Chronic Obstructive Pulmonary Disease (COPD)
 

Status: Recruiting

Condition Summary: Chronic Obstructive Pulmonary Disease (COPD)

 

Last Updated: 10 Jul 2017

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Cardiovascular Risk and Chronic Obstructive Pulmonary Disease
 

Status: Recruiting

Condition Summary: Chronic Obstructive Pulmonary Disease

 

Last Updated: 11 Jan 2017

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