Chronic obstructive pulmonary disease

Common Name(s)

Chronic obstructive pulmonary disease, COPD

Chronic obstructive pulmonary disease (COPD) is a progressive disease that makes breathing difficult. COPD is a general term describing several progressive lung diseases including emphysema, chronic bronchitis, refractory (non-reversible) asthma, and some forms of bronchiectasis. COPD is usually symptom free at first; but as the lung damage increases, symptoms begin to appear and then worsen over time. Symptoms of COPD may include coughing that produces large amounts of mucus, wheezing, shortness of breath, and chest tightness. COPD is caused by long-term exposure to lung irritants such as cigarette smoke and pollutants as well as genetic factors, including alpha 1 antitrypsin deficiency.

With COPD, less air flows in and out of the airways because of one or more of the following: the airways and air sacs of the lungs lose their elastic quality, the walls between many of the air sacs are destroyed, the walls of the airways become thick and inflamed, and/or the airways make more mucus than usual, which can clog them. COPD may be diagnosed using a noninvasive breathing test called spirometry. Spirometry can detect COPD before symptoms begin, and your doctor may advise you to be screened regularly for COPD if you have a history of smoking, exposure to toxins, fumes or pollutants or have a genetic predisposition to or family history of COPD. Your physician may order other tests to rule out other lung conditions and to determine the best treatment for your stage of COPD. Treatment includes medications and lung therapy. Surgery is sometimes necessary for those with severe emphysema. Although there is currently no cure for COPD, treatments and lifestyle changes can help patients feel better, stay more active, and slow the progress of the disease. If you or a family member has been diagnosed with COPD, talk with your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic obstructive pulmonary disease" for support, advocacy or research.

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COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

Last Updated: 25 Mar 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic obstructive pulmonary disease" for support, advocacy or research.

Logo
COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

http://www.copdfoundation.org

Last Updated: 25 Mar 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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General Resources

COPD Research Registry

The COPD Research Registry is a confidential database of individuals diagnosed with COPD or at risk of developing COPD who have consented to be contacted for participation in COPD research studies and clinical trials.

Uploaded By: COPD Foundation

Updated 21 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic obstructive pulmonary disease" returned 3909 free, full-text research articles on human participants. First 3 results:

Effects of the Chinese herb formula Yufeining on stable chronic obstructive pulmonary disease: A randomized, double-blind, placebo-controlled trial.
 

Author(s): Minli Hong, Chunlin Hong, Huinuan Chen, Gengshen Ke, Jinrong Huang, Xiaohua Huang, Yanhong Liu, Fengsen Li, Candong Li

Journal: Medicine (Baltimore). 2018 Sep;97(39):e12461.

 

A Chinese herb formula Yufeining (YFN) has showed promise in the treatment of stable chronic obstructive pulmonary disease (COPD), less is known that the impact of YFN in combination with standard Western treatments on lung inflammation. This study evaluated the safety and efficacy ...

Last Updated: 31 Dec 1969

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A retrospective study of Yiqibushenhuoxue decoction for the treatment of chronic obstructive pulmonary disease.
 

Author(s): Zhuying Li, Chunyan Tian, Xuehui Wang, Liqin Wang

Journal: Medicine (Baltimore). 2018 Aug;97(31):e11684.

 

This retrospective study aimed to investigate the effect and safety of Yiqibushenhuoxue decoction (YQBSHXD) for the treatment of chronic obstructive pulmonary disease (COPD).This study involved 120 cases of patients with COPD. These cases were assigned to an intervention group and ...

Last Updated: 31 Dec 1969

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The benefit of daily sputum suction via bronchoscopy in patients of chronic obstructive pulmonary disease with ventilators: A randomized controlled trial.
 

Author(s): Zhihao Qiao, Jianghong Yu, Kai Yu, Mengya Zhang

Journal: Medicine (Baltimore). 2018 Aug;97(31):e11631.

 

To compare the clinical values of bronchoscopic sputum suction and general sputum suction in respiratory failure patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) combined with sequential invasive-noninvasive mechanical ventilation at the pulmonary ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic obstructive pulmonary disease" returned 782 free, full-text review articles on human participants. First 3 results:

Transcutaneous electric nerve stimulation over acupoints for chronic obstructive pulmonary disease: Protocol for a systematic review and meta-analysis.
 

Author(s): Jia-Jia Wang, Yang Xie, Hu-Lei Zhao, Wei-Hong Han, Xiao-Chun Wang

Journal: Medicine (Baltimore). 2018 Jun;97(25):e11199.

 

There is a limited evidence concerning the efficacy of transcutaneous electric nerve stimulation over acupoints (Acu-TENS) for chronic obstructive pulmonary disease (COPD). Thus, this review aims to systematically determine the effect of Acu-TENS on COPD.

Last Updated: 31 Dec 1969

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Cigarette Smoke-Induced Acquired Dysfunction of Cystic Fibrosis Transmembrane Conductance Regulator in the Pathogenesis of Chronic Obstructive Pulmonary Disease.
 

Author(s): Juan Shi, Hui Li, Chao Yuan, Meihui Luo, Jun Wei, Xiaoming Liu

Journal:

 

Chronic obstructive pulmonary disease (COPD) is a disease state characterized by airflow limitation that is not fully reversible. Cigarette smoke and oxidative stress are main etiological risks in COPD. Interestingly, recent studies suggest a considerable overlap between chronic bronchitis ...

Last Updated: 31 Dec 1969

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Stroke risk among patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis.
 

Author(s): Yu Ree Kim, In Cheol Hwang, Yong Joo Lee, Eun Bee Ham, Dong Kyun Park, Sewan Kim

Journal: Clinics (Sao Paulo). 2018 ;73():e177.

 

Increased stroke risk among chronic obstructive pulmonary disease patients has not yet been established. In this study, we conducted a systematic review and meta-analysis to assess stroke risk among chronic obstructive pulmonary disease patients. PubMed, EMBASE, and the Cochrane Library ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Active for Life: Chronic Obstructive Pulmonary Disease
 

Status: Recruiting

Condition Summary: Chronic Obstructive Pulmonary Disease

 

Last Updated: 17 Sep 2018

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Imaging of Apoptosis in Chronic Obstructive Pulmonary Disease (COPD)
 

Status: Recruiting

Condition Summary: Chronic Obstructive Pulmonary Disease (COPD)

 

Last Updated: 13 Aug 2018

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Cardiovascular Risk and Chronic Obstructive Pulmonary Disease
 

Status: Recruiting

Condition Summary: Chronic Obstructive Pulmonary Disease

 

Last Updated: 15 Oct 2018

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