Cervical cancer

Common Name(s)

Cervical cancer

Cervical cancer is cancer that starts in the cervix, which is the small opening into the uterus from the vagina. Human papillomavirus (HPV) causes 99% of cervical cancers. There are many types of HPV, and they are categorized by low-risk and high-risk HPV. High-risk HPV types may cause normal cervical cells to turn into abnormal cervical cells. Overtime, these abnormal cervical cells may develop into cervical cancer. There may be no symptoms of cervical cancer at first but pelvic pain and bleeding from the vagina may happen later in more advanced stages of cervical cancer. Screening for precancerous and cancerous cervical cells is done through a Pap test, which is used to examine cells from the cervix under a microscope. Treatment may include surgery, radiation therapy, chemotherapy, or a combination.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Breast Friends

Breast Friends ensures that no woman goes through cancer alone. We are a unique resource for women, their family, friends, co-workers and community minimizing the fear and isolation of cancer. For over a decade our programs have empowered thousands with emotional support and hope. We are survivors and professionals helping others celebrate the joy of life.

Last Updated: 25 Mar 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 27 Apr 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Breast Friends

Breast Friends ensures that no woman goes through cancer alone. We are a unique resource for women, their family, friends, co-workers and community minimizing the fear and isolation of cancer. For over a decade our programs have empowered thousands with emotional support and hope. We are survivors and professionals helping others celebrate the joy of life.

http://www.breastfriends.org

Last Updated: 25 Mar 2013

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 27 Apr 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cervical cancer" returned 2845 free, full-text research articles on human participants. First 3 results:

Primary cervical cancer screening with human papillomavirus: end of study results from the ATHENA study using HPV as the first-line screening test.
 

Author(s): Thomas C Wright, Mark H Stoler, Catherine M Behrens, Abha Sharma, Guili Zhang, Teresa L Wright

Journal: Gynecol. Oncol.. 2015 Feb;136(2):189-97.

 

ATHENA evaluated the cobas HPV Test as the primary screen for cervical cancer in women ≥25years. This reports the 3-year end-of-study results comparing the performance of HPV primary screening to different screening and triage combinations.

Last Updated: 14 Feb 2015

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Assessing the effectiveness of a cervical cancer screening program in a hospital-based study.
 

Author(s): Yi Yang, Jing He Lang, You Fang Wang, Xue Mei Cheng, Yu Pin Cai, Hui Li, Bao Li Zhu, Rui Fen Zhang

Journal: Biomed. Environ. Sci.. 2015 Jan;28(1):80-4.

 

To study the microbiological contamination of kitchen dishcloths in Chinese housholds, 1010 'in-use' kitchen dishcloths were collected from residential premises in Beijing and Shanghai, and they were sent to the laboratory for microbiological quality analysis. The aerobic plate counts ...

Last Updated: 8 Jan 2015

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Involvement of reactive oxygen species in the mechanisms associated with cervical cancer specific treatment.
 

Author(s): S Marinescu, R Anghel, M I Gruia, M Beuran

Journal: Chirurgia (Bucur). ;109(6):806-11.

 

Cervical cancer represents a genuine health issue in Romania.The courses of treatment applied are complex, and the accompanying biochemical mechanisms are yet to be fully understood. Thus, radiotherapy, which induces reactive oxygen species, can lead to failure of treatment in hypoxic ...

Last Updated: 6 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cervical cancer" returned 249 free, full-text review articles on human participants. First 3 results:

Leukemoid reaction in cervical cancer: a case report and review of the literature.
 

Author(s): Li Qing, Tao Xiang, Zhang Guofu, Feng Weiwei

Journal:

 

The presentation of a leukemoid reaction in cervical cancers is rare. A leukemoid reaction is defined as leukocytosis associated with a cause outside the bone marrow, with the white blood cell count (WBC) exceeding 50*109/L. Two cervical cancers presenting with leukemoid reactions ...

Last Updated: 20 Sep 2014

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Multistep model of cervical cancer: participation of miRNAs and coding genes.
 

Author(s): Angelica Judith Granados López, Jesús Adrián López

Journal:

 

Aberrant miRNA expression is well recognized as an important step in the development of cancer. Close to 70 microRNAs (miRNAs) have been implicated in cervical cancer up to now, nevertheless it is unknown if aberrant miRNA expression causes the onset of cervical cancer. One of the ...

Last Updated: 6 Sep 2014

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Prognostic significance of overexpressed p16INK4a in patients with cervical cancer: a meta-analysis.
 

Author(s): Jiaying Lin, Andreas E Albers, Jinbao Qin, Andreas M Kaufmann

Journal:

 

p16INK4a is a tumor suppressor protein which is induced in cells upon the interaction of high-risk HPV E7 with the retinoblastoma protein by a positive feedback loop, but cannot exert its suppressing effect. Previous reports suggested that p16INK4a immunostaining allows precise identification ...

Last Updated: 5 Sep 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

ADXS11-001 High Dose HPV+ Cervical Cancer
 

Status: Recruiting

Condition Summary: Effects of Immunotherapy; Metastatic/Recurrent Cervical Cancer; Cervical Adenocarcinoma; Cervical Adenosquamous Cell Carcinoma; Cervical Squamous Cell Carcinoma; Cervical Small Cell Carcinoma; Stage III Cervical Cancer; Stage IVA Cervical Cancer; Stage IVB Cervical Cancer

 

Last Updated: 25 Feb 2015

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Eribulin Mesylate in Treating Patients With Advanced or Recurrent Cervical Cancer
 

Status: Recruiting

Condition Summary: Recurrent Cervical Cancer; Stage IIIA Cervical Cancer; Stage IIIB Cervical Cancer; Stage IVA Cervical Cancer; Stage IVB Cervical Cancer

 

Last Updated: 12 Mar 2015

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Cisplatin and Radiation Therapy With or Without Triapine in Treating Patients With Previously Untreated Stage IB-IVA Cervical Cancer or Stage II-IVA Vaginal Cancer
 

Status: Recruiting

Condition Summary: Cervical Adenocarcinoma; Cervical Adenosquamous Carcinoma; Cervical Squamous Cell Carcinoma; Stage IB2 Cervical Cancer; Stage II Vaginal Cancer; Stage IIA1 Cervical Cancer; Stage IIA2 Cervical Cancer; Stage IIB Cervical Cancer; Stage III Vaginal Cancer; Stage IIIA Cervical Cancer; Stage IIIB Cervical Cancer; Stage IVA Cervical Cancer; Stage IVA Vaginal Cancer; Vaginal Adenocarcinoma; Vaginal Adenosquamous Carcinoma; Vaginal Squamous Cell Carcinoma

 

Last Updated: 28 May 2015

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