Cervical cancer

Common Name(s)

Cervical cancer

Cervical cancer is cancer that starts in the cervix, which is the small opening into the uterus from the vagina. Human papillomavirus (HPV) causes 99% of cervical cancers. There are many types of HPV, and they are categorized by low-risk and high-risk HPV. High-risk HPV types may cause normal cervical cells to turn into abnormal cervical cells. Overtime, these abnormal cervical cells may develop into cervical cancer. There may be no symptoms of cervical cancer at first but pelvic pain and bleeding from the vagina may happen later in more advanced stages of cervical cancer. Screening for precancerous and cancerous cervical cells is done through a Pap test, which is used to examine cells from the cervix under a microscope. Treatment may include surgery, radiation therapy, chemotherapy, or a combination.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Breast Friends

Breast Friends ensures that no woman goes through cancer alone. We are a unique resource for women, their family, friends, co-workers and community minimizing the fear and isolation of cancer. For over a decade our programs have empowered thousands with emotional support and hope. We are survivors and professionals helping others celebrate the joy of life.

Last Updated: 25 Mar 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Breast Friends

Breast Friends ensures that no woman goes through cancer alone. We are a unique resource for women, their family, friends, co-workers and community minimizing the fear and isolation of cancer. For over a decade our programs have empowered thousands with emotional support and hope. We are survivors and professionals helping others celebrate the joy of life.

http://www.breastfriends.org

Last Updated: 25 Mar 2013

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cervical cancer" returned 2631 free, full-text research articles on human participants. First 3 results:

[Uterine cervical cancer screening in kitakyushu city: present and future].
 

Author(s): Yusuke Matsuura, Haruko Oka, Kazuhiro Yamagata, Joji Kikuchi, Isao Inoue, Nobuyuki Ohkubo, Naoyuki Toki, Toshinori Kawagoe, Toru Hachisuga, Masamichi Kashimura

Journal: J. UOEH. 2014 Sep;36(3):205-15.

 

Uterine cervical cancer is the most common primary gynecologic malignant tumor in Japan. Conventional cervical screening Papanicolaou (Pap) test has been shown to be extremely effective in reducing cervical cancer incidence and mortality, but the consultation rate for cancer screening ...

Last Updated: 16 Sep 2014

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Type distribution of human papillomavirus among adult women diagnosed with invasive cervical cancer (stage 1b or higher) in New Zealand.
 

Author(s): Peter Sykes, Kusuma Gopala, Ai Ling Tan, Diane Kenwright, Simone Petrich, Anco Molijn, Jing Chen

Journal:

 

Human papillomavirus (HPV) is the necessary cause of cervical cancer. Published data on the epidemiology of HPV in women with invasive cervical cancer (ICC) in New Zealand (NZ) are limited. This cross-sectional study investigated the distribution of high-risk and low-risk HPV types ...

Last Updated: 16 Jul 2014

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Multiple neoplasms among cervical cancer patients in the material of the lower Silesian cancer registry.
 

Author(s): Barbara Izmajłowicz, Jan Kornafel, Jerzy Błaszczyk

Journal: Adv Clin Exp Med. ;23(3):433-40.

 

According to the definition by the International Agency for Research on Cancer (IARC), primary multiple neoplasms are two or more neoplasms of different histopathological build in one organ, or two or more tumors occurring in one patient, regardless of the time of their occurrence ...

Last Updated: 1 Jul 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cervical cancer" returned 237 free, full-text review articles on human participants. First 3 results:

Immunologic treatments for precancerous lesions and uterine cervical cancer.
 

Author(s): Patrizia Vici, Luciano Mariani, Laura Pizzuti, Domenico Sergi, Luigi Di Lauro, Enrico Vizza, Federica Tomao, Silverio Tomao, Claudia Cavallotti, Francesca Paolini, Aldo Venuti

Journal:

 

Development of HPV-associated cancers not only depends on efficient negative regulation of cell cycle control that supports the accumulation of genetic damage, but also relies on immune evasion that enable the virus to go undetected for long periods of time. In this way, HPV-related ...

Last Updated: 2 Apr 2014

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Deregulation of the miRNAs expression in cervical cancer: human papillomavirus implications.
 

Author(s): Yazmín Gómez-Gómez, Jorge Organista-Nava, Patricio Gariglio

Journal: Biomed Res Int. 2013 ;2013():407052.

 

MicroRNAs (miRNAs) are a class of small non coding RNAs of 18-25 nucleotides in length. The temporal or short-lived expression of the miRNAs modulates gene expression post transcriptionally. Studies have revealed that miRNAs deregulation correlates and is involved with the initiation ...

Last Updated: 3 Feb 2014

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Viral and cellular biomarkers in the diagnosis of cervical intraepithelial neoplasia and cancer.
 

Author(s): Maria Lina Tornesello, Luigi Buonaguro, Paolo Giorgi-Rossi, Franco M Buonaguro

Journal: Biomed Res Int. 2013 ;2013():519619.

 

Cervical cancer arises from cells localized in the ectoendocervical squamocolumnar junction of the cervix persistently infected with one of about 13 human papillomavirus (HPV) genotypes. The majority of HPV infections induces low grade squamous epithelial lesions that in more than ...

Last Updated: 2 Jan 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

ADXS11-001 High Dose HPV+ Cervical Cancer
 

Status: Not yet recruiting

Condition Summary: Effects of Immunotherapy; Metastatic/Recurrent Cervical Cancer; Cervical Adenocarcinoma; Cervical Adenosquamous Cell Carcinoma; Cervical Squamous Cell Carcinoma; Cervical Small Cell Carcinoma; Stage III Cervical Cancer; Stage IVA Cervical Cancer; Stage IVB Cervical Cancer

 

Last Updated: 16 Jun 2014

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Eribulin Mesylate in Treating Patients With Advanced or Recurrent Cervical Cancer
 

Status: Recruiting

Condition Summary: Recurrent Cervical Cancer; Stage IIIA Cervical Cancer; Stage IIIB Cervical Cancer; Stage IVA Cervical Cancer; Stage IVB Cervical Cancer

 

Last Updated: 21 Jul 2014

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MRI and PET Imaging in Predicting Treatment Response in Patients With Stage IB-IVA Cervical Cancer
 

Status: Recruiting

Condition Summary: Cervical Adenocarcinoma; Cervical Adenosquamous Cell Carcinoma; Cervical Squamous Cell Carcinoma; Recurrent Cervical Cancer; Stage IB Cervical Cancer; Stage IIA Cervical Cancer; Stage IIB Cervical Cancer; Stage IIIA Cervical Cancer; Stage IIIB Cervical Cancer; Stage IVA Cervical Cancer

 

Last Updated: 9 Oct 2014

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