Cervical cancer

Common Name(s)

Cervical cancer

Cervical cancer is cancer that starts in the cervix, which is the small opening into the uterus from the vagina. Human papillomavirus (HPV) causes 99% of cervical cancers. There are many types of HPV, and they are categorized by low-risk and high-risk HPV. High-risk HPV types may cause normal cervical cells to turn into abnormal cervical cells. Overtime, these abnormal cervical cells may develop into cervical cancer. There may be no symptoms of cervical cancer at first but pelvic pain and bleeding from the vagina may happen later in more advanced stages of cervical cancer. Screening for precancerous and cancerous cervical cells is done through a Pap test, which is used to examine cells from the cervix under a microscope. Treatment may include surgery, radiation therapy, chemotherapy, or a combination.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Breast Friends

Breast Friends ensures that no woman goes through cancer alone. We are a unique resource for women, their family, friends, co-workers and community minimizing the fear and isolation of cancer. For over a decade our programs have empowered thousands with emotional support and hope. We are survivors and professionals helping others celebrate the joy of life.

Last Updated: 25 Mar 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Breast Friends

Breast Friends ensures that no woman goes through cancer alone. We are a unique resource for women, their family, friends, co-workers and community minimizing the fear and isolation of cancer. For over a decade our programs have empowered thousands with emotional support and hope. We are survivors and professionals helping others celebrate the joy of life.

http://www.breastfriends.org

Last Updated: 25 Mar 2013

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cervical cancer" returned 3631 free, full-text research articles on human participants. First 3 results:

[Effect of RbAp48 knockdown on migration and invasion of human cervical cancer cell line MS751 in vitro].
 

Author(s): Jingjing Zhong, Xurui Yang, Meiqing Mai, Dandan Wang, Lin Lv, Jinjun Rao

Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2015 Nov;35(11):1564-9.

 

To investigate the effect of RbAp48 knockdown on the migration and invasion of human cervical cancer cells and explore the mechanism.

Last Updated: 26 Nov 2015

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A cost-utility analysis of cervical cancer screening and human papillomavirus vaccination in the Philippines.
 

Author(s): Anna Melissa Guerrero, Anne Julienne Genuino, Melanie Santillan, Naiyana Praditsitthikorn, Varit Chantarastapornchit, Yot Teerawattananon, Marissa Alejandria, Jean Anne Toral

Journal:

 

Cervical cancer is the second leading cause of cancer cases and deaths among Filipino women because of inadequate access to screening and treatment services. This study aims to evaluate the health and economic benefits of HPV vaccination and its combination with different screening ...

Last Updated: 30 Jul 2015

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Total Laparoscopic Versus Laparotomic Radical Hysterectomy and Lymphadenectomy in Cervical Cancer: An Observational Study of 13-Year Experience.
 

Author(s): Meizhu Xiao, Zhenyu Zhang

Journal: Medicine (Baltimore). 2015 Jul;94(30):e1264.

 

This article aims to review our 13-year experience in the treatment of patients with cervical cancer by comparing total laparoscopic radical hysterectomy and lymphadenectomy with laparotomy.We reviewed all patients undergoing total laparoscopic or laparotomic radical hysterectomy ...

Last Updated: 30 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cervical cancer" returned 309 free, full-text review articles on human participants. First 3 results:

Performance of alternative strategies for primary cervical cancer screening in sub-Saharan Africa: systematic review and meta-analysis of diagnostic test accuracy studies.
 

Author(s): Joël Fokom-Domgue, Christophe Combescure, Victoire Fokom-Defo, Pierre Marie Tebeu, Pierre Vassilakos, André Pascal Kengne, Patrick Petignat

Journal:

 

To assess and compare the accuracy of visual inspection with acetic acid (VIA), visual inspection with Lugol's iodine (VILI), and human papillomavirus (HPV) testing as alternative standalone methods for primary cervical cancer screening in sub-Saharan Africa.

Last Updated: 4 Jul 2015

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HPV testing as a screen for cervical cancer.
 

Author(s): Annekathryn Goodman

Journal:

 

Human papillomavirus (HPV) has been identified as a necessary factor in the development of pre-invasive and invasive cancers of the lower genital tract, of which cervical cancer is the most prevalent. A molecular understanding of malignant transformation and epidemiologic information ...

Last Updated: 1 Jul 2015

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Modern radiation therapy and potential fertility preservation strategies in patients with cervical cancer undergoing chemoradiation.
 

Author(s): Pirus Ghadjar, Volker Budach, Christhardt Köhler, Andreas Jantke, Simone Marnitz

Journal:

 

Young patients with cervical cancer who undergo chemoradiation might be interested in fertility preservation, not only dependent upon the use of a gestational carrier as maybe achieved by the use of ovarian transposition and cryo-conservation of oocytes or ovarian tissue, but may ...

Last Updated: 19 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Eribulin Mesylate in Treating Patients With Advanced or Recurrent Cervical Cancer
 

Status: Recruiting

Condition Summary: Recurrent Cervical Cancer; Stage IIIA Cervical Cancer; Stage IIIB Cervical Cancer; Stage IVA Cervical Cancer; Stage IVB Cervical Cancer

 

Last Updated: 8 Jul 2015

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AZD1775, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer
 

Status: Recruiting

Condition Summary: Stage IB Cervical Cancer; Stage IIA Cervical Cancer; Stage IIB Cervical Cancer; Stage IIIA Cervical Cancer; Stage IIIB Cervical Cancer

 

Last Updated: 11 Jan 2016

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Cisplatin and Radiation Therapy With or Without Carboplatin and Paclitaxel in Patients With Locally Advanced Cervical Cancer
 

Status: Recruiting

Condition Summary: Cervical Adenocarcinoma; Cervical Adenosquamous Carcinoma; Cervical Squamous Cell Carcinoma; Chemotherapeutic Agent Toxicity; Cognitive Side Effects of Cancer Therapy; Psychological Impact of Cancer; Radiation Toxicity; Sexual Dysfunction and Infertility; Stage IB Cervical Cancer; Stage IIA Cervical Cancer; Stage IIB Cervical Cancer; Stage III Cervical Cancer; Stage IVA Cervical Cancer

 

Last Updated: 9 Feb 2016

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