Essential tremor

Common Name(s)

Essential tremor, Benign Essential Tremor Syndrome

Essential tremor is a disorder of the nervous system that causes involuntary, rhythmic shaking (tremor), especially in the hands. It involves tremor without any other signs or symptoms, and is distinguished from tremor that results from other disorders or known causes, such as tremors seen with Parkinson disease or head trauma.  Essential tremor (sometimes called benign essential tremor) is the most common of the more than 20 types of tremor. The causes of essential tremor are unknown. Several genes as well as environmental factors likely play a role in a person's risk of developing this complex condition.  In mild cases, treatment may not be necessary. In cases where symptoms interfere with daily living, medications may help to relieve symptoms.  

 

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential tremor" for support, advocacy or research.

International Essential Tremor Foundation

The International Essential Tremor Foundation is a worldwide organization that funds research to find the cause of essential tremor (ET) that will lead to better treatment and a cure, increases public awareness about ET, and provides educational materials, tools, and support for healthcare providers, the public, and those affected by ET.

Last Updated: 27 Dec 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential tremor" for support, advocacy or research.

International Essential Tremor Foundation

The International Essential Tremor Foundation is a worldwide organization that funds research to find the cause of essential tremor (ET) that will lead to better treatment and a cure, increases public awareness about ET, and provides educational materials, tools, and support for healthcare providers, the public, and those affected by ET.

www.essentialtremor.org

Last Updated: 27 Dec 2012

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General Support Organizations

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General Resources

Essential Tremor Website

Online source of free educational materials, that include brochures, flyers, webinars, videos, physician referral and support.

Updated 27 Dec 2012

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Blogs

Tremor Talk Blog

Posting of brief entries, links to news, photos, and other conversation pieces to help keep those affected by ET informed of the latest happenings.

Updated 27 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential tremor" returned 324 free, full-text research articles on human participants. First 3 results:

Treatment of Medically Refractory Essential Tremor.
 

Author(s): Elan D Louis

Journal: N. Engl. J. Med.. 2016 Aug;375(8):792-3.

 

Last Updated: 25 Aug 2016

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A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor.
 

Author(s): W Jeffrey Elias, Nir Lipsman, William G Ondo, Pejman Ghanouni, Young G Kim, Wonhee Lee, Michael Schwartz, Kullervo Hynynen, Andres M Lozano, Binit B Shah, Diane Huss, Robert F Dallapiazza, Ryder Gwinn, Jennifer Witt, Susie Ro, Howard M Eisenberg, Paul S Fishman, Dheeraj Gandhi, Casey H Halpern, Rosalind Chuang, Kim Butts Pauly, Travis S Tierney, Michael T Hayes, G Rees Cosgrove, Toshio Yamaguchi, Keiichi Abe, Takaomi Taira, Jin W Chang

Journal: N. Engl. J. Med.. 2016 Aug;375(8):730-9.

 

Uncontrolled pilot studies have suggested the efficacy of focused ultrasound thalamotomy with magnetic resonance imaging (MRI) guidance for the treatment of essential tremor.

Last Updated: 25 Aug 2016

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Dose-escalation study of octanoic acid in patients with essential tremor.
 

Author(s): Bernhard Voller, Emily Lines, Gayle McCrossin, Sule Tinaz, Codrin Lungu, George Grimes, Judith Starling, Gopal Potti, Peter Buchwald, Dietrich Haubenberger, Mark Hallett

Journal: J. Clin. Invest.. 2016 Apr;126(4):1451-7.

 

Recently, 1-octanol has been shown to have efficacy in treating patients with essential tremor (ET). The primary metabolite of 1-octanol is octanoic acid (OA), which is now thought to be the active substance that mediates tremor suppression. Our aim was to describe the maximum tolerated ...

Last Updated: 2 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential tremor" returned 32 free, full-text review articles on human participants. First 3 results:

Challenges in essential tremor genetics.
 

Author(s): L N Clark, E D Louis

Journal: Rev. Neurol. (Paris). ;171(6-7):466-74.

 

The field of essential tremor (ET) genetics remains extremely challenging. The relative lack of progress in understanding the genetic etiology of ET, however, does not reflect the lack of a genetic contribution, but rather, the presence of substantial phenotypic and genotypic heterogeneity. ...

Last Updated: 15 Jun 2015

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Neuroimaging essentials in essential tremor: a systematic review.
 

Author(s): Sarvi Sharifi, Aart J Nederveen, Jan Booij, Anne-Fleur van Rootselaar

Journal:

 

Essential tremor is regarded to be a disease of the central nervous system. Neuroimaging is a rapidly growing field with potential benefits to both diagnostics and research. The exact role of imaging techniques with respect to essential tremor in research and clinical practice is ...

Last Updated: 28 Jul 2014

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MR-guided focused ultrasound: a new generation treatment of Parkinson's disease, essential tremor and neuropathic pain.
 

Author(s): Pawel Piotr Dobrakowski, Agnieszka Kamila Machowska-Majchrzak, Beata Labuz-Roszak, Krzysztof Grzegorz Majchrzak, Ewa Kluczewska, Krystyna Barbara PierzchaƂa

Journal: Interv Neuroradiol. ;20(3):275-82.

 

The application of high intense focused ultrasound (HIFU) is currently the subject of many experimental and clinical trials. The combination of HIFU with MRI guidance known as MR-guided focused ultrasound (MRgFUS) appears to be particularly promising to ablate tissues located deep ...

Last Updated: 30 Jun 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
 

Status: Recruiting

Condition Summary: Tremor; Essential Tremor; Parkinson Disease; Radiosurgery; Quality of Life

 

Last Updated: 9 Dec 2015

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Demand-driven Management of Essential Tremor
 

Status: Recruiting

Condition Summary: Essential Tremor

 

Last Updated: 30 Nov 2015

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Gamma Knife Radiosurgery for Treatment of Essential Tremor
 

Status: Recruiting

Condition Summary: Essential Tremor

 

Last Updated: 20 Apr 2016

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