Essential tremor

Common Name(s)

Essential tremor, Benign Essential Tremor Syndrome

Essential tremor is a disorder of the nervous system that causes involuntary, rhythmic shaking (tremor), especially in the hands. It involves tremor without any other signs or symptoms, and is distinguished from tremor that results from other disorders or known causes, such as tremors seen with Parkinson disease or head trauma.  Essential tremor (sometimes called benign essential tremor) is the most common of the more than 20 types of tremor. The causes of essential tremor are unknown. Several genes as well as environmental factors likely play a role in a person's risk of developing this complex condition.  In mild cases, treatment may not be necessary. In cases where symptoms interfere with daily living, medications may help to relieve symptoms.  

 

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential tremor" for support, advocacy or research.

International Essential Tremor Foundation

The International Essential Tremor Foundation is a worldwide organization that funds research to find the cause of essential tremor (ET) that will lead to better treatment and a cure, increases public awareness about ET, and provides educational materials, tools, and support for healthcare providers, the public, and those affected by ET.

Last Updated: 27 Dec 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Essential tremor" for support, advocacy or research.

International Essential Tremor Foundation

The International Essential Tremor Foundation is a worldwide organization that funds research to find the cause of essential tremor (ET) that will lead to better treatment and a cure, increases public awareness about ET, and provides educational materials, tools, and support for healthcare providers, the public, and those affected by ET.

www.essentialtremor.org

Last Updated: 27 Dec 2012

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General Support Organizations

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General Resources

Essential Tremor Website

Online source of free educational materials, that include brochures, flyers, webinars, videos, physician referral and support.

Updated 27 Dec 2012

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Blogs

Tremor Talk Blog

Posting of brief entries, links to news, photos, and other conversation pieces to help keep those affected by ET informed of the latest happenings.

Updated 27 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Essential tremor" returned 338 free, full-text research articles on human participants. First 3 results:

A computerized tablet system for evaluating treatment of essential tremor by magnetic resonance guided focused ultrasound.
 

Author(s): Fred Tam, Yuexi Huang, Michael L Schwartz, Tom A Schweizer, Kullervo Hynynen, Simon J Graham

Journal:

 

Transcranial magnetic resonance guided focused ultrasound is an emerging technology under evaluation for treatment of essential tremor, a prevalent movement disorder. A qualitative evaluation is performed by a clinician periodically during the procedure to maximize treatment effects ...

Last Updated: 17 Apr 2017

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A Network Model of Local Field Potential Activity in Essential Tremor and the Impact of Deep Brain Stimulation.
 

Author(s): Nada Yousif, Michael Mace, Nicola Pavese, Roman Borisyuk, Dipankar Nandi, Peter Bain

Journal:

 

Essential tremor (ET), a movement disorder characterised by an uncontrollable shaking of the affected body part, is often professed to be the most common movement disorder, affecting up to one percent of adults over 40 years of age. The precise cause of ET is unknown, however pathological ...

Last Updated: 9 Jan 2017

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A step toward essential tremor gene discovery: identification of extreme phenotype and screening of HTRA2 and ANO3.
 

Author(s): Mathilde Renaud, Christophe Marcel, Gabrielle Rudolf, Mickaël Schaeffer, Ouhaïd Lagha-Boukbiza, Jean-Baptiste Chanson, Jamel Chelly, Mathieu Anheim, Christine Tranchant

Journal:

 

Essential tremor (ET) is characterized by a frequent family history. No monogenic form of ET has been identified. We aimed at exploring ET patients to identify distinct subgroups and facilitate the identification of ET genes. We tested for the presence of HTRA2 p.G399S, and ANO3 p. ...

Last Updated: 24 Nov 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Essential tremor" returned 31 free, full-text review articles on human participants. First 3 results:

Non-motor symptoms in essential tremor: A review of the current data and state of the field.
 

Author(s): Elan D Louis

Journal: Parkinsonism Relat. Disord.. 2016 Jan;22 Suppl 1():S115-8.

 

The motor features of essential tremor (ET) include its hallmark element, kinetic tremor, yet non-motor features are increasingly being recognized as an accompanying part of what was previously viewed as a solely motor disorder. Given the evolving state of the ET field with respect ...

Last Updated: 26 Nov 2015

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Essential Tremor: A Common Disorder of Purkinje Neurons?
 

Author(s): Elan D Louis

Journal: Neuroscientist. 2016 Apr;22(2):108-18.

 

Essential tremor (ET) is one of the most common neurological diseases, with an estimated 7 million affected individuals in the United States. Postmortem studies in the past few years have resulted in new knowledge as well as a new formulation of disease pathophysiology. This new formulation ...

Last Updated: 17 Mar 2016

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Challenges in essential tremor genetics.
 

Author(s): L N Clark, E D Louis

Journal: Rev. Neurol. (Paris). ;171(6-7):466-74.

 

The field of essential tremor (ET) genetics remains extremely challenging. The relative lack of progress in understanding the genetic etiology of ET, however, does not reflect the lack of a genetic contribution, but rather, the presence of substantial phenotypic and genotypic heterogeneity. ...

Last Updated: 15 Jun 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Demand-driven Management of Essential Tremor
 

Status: Recruiting

Condition Summary: Essential Tremor

 

Last Updated: 24 May 2017

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Responsive Deep Brain Stimulator for Essential Tremor
 

Status: Recruiting

Condition Summary: Essential Tremor

 

Last Updated: 22 Feb 2017

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A Phase 2 RCT Study of CX-8998 for Essential Tremor
 

Status: Recruiting

Condition Summary: Essential Tremor

 

Last Updated: 23 Jun 2017

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