Carpal tunnel syndrome

Common Name(s)

Carpal tunnel syndrome

Carpal tunnel syndrome (CTS) is a condition that causes pain, numbness and tingling in the hand, which may sometimes extend to the wrist and arm as well. The carpal tunnel is a structure that is found at the connection of the wrist and hand. It is formed by a layer of connective tissue that runs over the wrist bones, tendons and nerves going to the hand. CTS occurs when this area becomes tightened and inflamed, causing compression of the nerve.

Roughly 3-6% of adults are affected by CTS, and prevalence increases with age. Individuals with smaller wrists are more likely to be affected by CTS, putting women at greater risk than men. Injury or repetitive motions of the wrist may also cause CTS, such as in individuals who perform repetitive motion such as typing or handling vibrating tools. Other risk factors include conditions of the nervous system, obesity, kidney failure, and thyroid disorders. There are also familial cases of CTS.

Individuals affected by CTS will usually first experience occasional numbness or tingling in the thumb and fingers. Other early symptoms include weakness in the hand and wrist and difficulty grasping items. CTS progresses into more painful and enduring symptoms throughout the wrist region. If left untreated, the nerve and muscle may be permanently damaged. After symptoms are reported, CTS is diagnosed by physical exam, medical imaging, electrical impulse measurements, and other nerve studies.

Treatment for CTS may help prevent symptoms from progressing. Resting and applying ice to the hands may help reduce swelling. Wearing a splint, especially at night, may also help reduce symptoms. Medications, such as anti-inflammatory drugs, may be given as pills or as injections. In severe, long-term cases, surgery may be necessary. If you are experiencing CTS, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Carpal tunnel syndrome" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Carpal tunnel syndrome" returned 524 free, full-text research articles on human participants. First 3 results:

[Clinical auxiliary diagnosis value of high frequency ultrasonographic measurements of the thickness of transverse carpal ligaments in carpal tunnel syndrome patients].
 

Author(s): L Xu, F M Chen, L Wang, P X Zhang, X R Jiang

Journal: Beijing Da Xue Xue Bao. 2016 Apr;48(2):341-5.

 

To evaluate the meaning and value of high-frequency ultrasound in the diagnosis of carpal tunnel syndrome (CTS).

Last Updated: 15 Apr 2016

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Acetyl-L-carnitine (ALCAR) to enhance nerve regeneration in carpal tunnel syndrome: study protocol for a randomized, placebo-controlled trial.
 

Author(s): Matthew W T Curran, Jaret Olson, Michael Morhart, Dory Sample, K Ming Chan

Journal:

 

Carpal tunnel syndrome (CTS) is the most common form of peripheral nerve injury, affecting approximately 3 % of the population. While surgery is effective in mild and moderate cases, nerve and functional recovery are often not complete in severe cases. Therefore, there is a need for ...

Last Updated: 15 Apr 2016

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Pain, depression and sleep disorders in patients with diabetic and nondiabetic carpal tunnel syndrome: a vicious cycle.
 

Author(s): Nermin Tanik, Umit Sarp, Mehmet Ucar, Asuman Celikbilek, Ozlem Balbaloglu, Hakan Ak, Tugay Atalay, Hasan Onur Arik, Mehmet Yavuz Okyay, Levent Ertugrul Inan

Journal: Arq Neuropsiquiatr. 2016 Mar;74(3):207-11.

 

Carpal tunnel syndrome (CTS) is a condition involving nerve entrapment that often leads to chronic neuropathic pain. We aimed to evaluate sleep quality and related parameters in diabetic and non-diabetic CTS patients.

Last Updated: 7 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Carpal tunnel syndrome" returned 51 free, full-text review articles on human participants. First 3 results:

Lipofibromatous hamartoma of the digital branches of the median nerve presenting as carpal tunnel syndrome: A rare case report with review of the literature.
 

Author(s): Ranjan Agrawal, Cheena Garg, Arjun Agarwal, Parbodh Kumar

Journal: Indian J Pathol Microbiol. ;59(1):96-8.

 

Lipofibromatous hamartoma (LFH) is a rare, benign fibrofatty tumor composed of a proliferation of mature adipocytes within peripheral nerves, which form a palpable neurogenic mass. It affects the median nerve in 66-80% of cases, causing pain and sensory and motor deficits in the affected ...

Last Updated: 10 Mar 2016

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Endoscopic and Open Release Similarly Safe for the Treatment of Carpal Tunnel Syndrome. A Systematic Review and Meta-Analysis.
 

Author(s): Haris S Vasiliadis, Adriani Nikolakopoulou, Ian Shrier, Michael P Lunn, Ruth Brassington, Rob J P Scholten, Georgia Salanti

Journal:

 

The Endoscopic Release of Carpal Tunnel Syndrome (ECTR) is a minimal invasive approach for the treatment of Carpal Tunnel Syndrome. There is scepticism regarding the safety of this technique, based on the assumption that this is a rather "blind" procedure and on the high number of ...

Last Updated: 17 Dec 2015

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Carpal tunnel syndrome and work.
 

Author(s): Lisa Newington, E Clare Harris, Karen Walker-Bone

Journal: Best Pract Res Clin Rheumatol. 2015 Jun;29(3):440-53.

 

Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome, and it frequently presents in working-aged adults. Its mild form causes 'nuisance' symptoms including dysaesthesia and nocturnal waking. At its most severe, CTS can significantly impair motor function ...

Last Updated: 27 Nov 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Static Magnetic Therapy for Carpal Tunnel Syndrome
 

Status: Recruiting

Condition Summary: Carpal Tunnel Syndrome

 

Last Updated: 17 Nov 2015

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The Effect of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome
 

Status: Recruiting

Condition Summary: Carpal Tunnel Syndrome

 

Last Updated: 10 Jun 2016

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Assessment of the Effectiveness of Ultrasound-guided Acupuncture in the Management of Carpal Tunnel Syndrome
 

Status: Not yet recruiting

Condition Summary: Carpal Tunnel Syndrome

 

Last Updated: 18 Aug 2016

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