Carpal tunnel syndrome

Common Name(s)

Carpal tunnel syndrome

Carpal tunnel syndrome (CTS) is a condition that causes pain, numbness and tingling in the hand, which may sometimes extend to the wrist and arm as well. The carpal tunnel is a structure that is found at the connection of the wrist and hand. It is formed by a layer of connective tissue that runs over the wrist bones, tendons and nerves going to the hand. CTS occurs when this area becomes tightened and inflamed, causing compression of the nerve.

Roughly 3-6% of adults are affected by CTS, and prevalence increases with age. Individuals with smaller wrists are more likely to be affected by CTS, putting women at greater risk than men. Injury or repetitive motions of the wrist may also cause CTS, such as in individuals who perform repetitive motion such as typing or handling vibrating tools. Other risk factors include conditions of the nervous system, obesity, kidney failure, and thyroid disorders. There are also familial cases of CTS.

Individuals affected by CTS will usually first experience occasional numbness or tingling in the thumb and fingers. Other early symptoms include weakness in the hand and wrist and difficulty grasping items. CTS progresses into more painful and enduring symptoms throughout the wrist region. If left untreated, the nerve and muscle may be permanently damaged. After symptoms are reported, CTS is diagnosed by physical exam, medical imaging, electrical impulse measurements, and other nerve studies.

Treatment for CTS may help prevent symptoms from progressing. Resting and applying ice to the hands may help reduce swelling. Wearing a splint, especially at night, may also help reduce symptoms. Medications, such as anti-inflammatory drugs, may be given as pills or as injections. In severe, long-term cases, surgery may be necessary. If you are experiencing CTS, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Carpal tunnel syndrome" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Carpal tunnel syndrome" returned 508 free, full-text research articles on human participants. First 3 results:

Relaxin Modulates the Expression of MMPs and TIMPs in Fibroblasts of Patients with Carpal Tunnel Syndrome.
 

Author(s): Young Mi Kang, Hwan Mo Lee, Seong Hwan Moon, Ho Kang, Yun Rak Choi

Journal: Yonsei Med. J.. 2017 Mar;58(2):415-422.

 

The aim of this study was to investigate the anti-fibrotic effect of relaxin in subsynovial fibroblasts activated by transforming growth factor beta (TGF-β).

Last Updated: 25 Jan 2017

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[Socio professional impact of surgical release of carpal tunnel syndrome].
 

Author(s): Aouatef Mahfoudh Kraiem, Hajer Hnia, Lamia Bouzgarrou, Mohamed Adnène Henchi, Taoufik Khalfallah

Journal:

 

The objective was studying the socio-professional impact of release surgery for carpal tunnel syndrom (CTS). We conducted a cross-sectional study of patients operated for work-related CTS; data were collected in the Occupational Health Department at the University Hospital Tahar Sfar ...

Last Updated: 1 Nov 2016

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Association of a high normalized protein catabolic rate and low serum albumin level with carpal tunnel syndrome in hemodialysis patients.
 

Author(s): Wen-Hung Huang, Ching-Wei Hsu, Cheng-Hao Weng, Tzung-Hai Yen, Jui-Hsiang Lin, Meng Lee

Journal: Medicine (Baltimore). 2016 Jun;95(26):e4050.

 

Carpal tunnel syndrome (CTS) is the most common mononeuropathy in patients with end-stage renal disease (ESRD). The association between chronic inflammation and CTS in hemodialysis (HD) patients has rarely been investigated. HD patients with a high normalized protein catabolic rate ...

Last Updated: 2 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Carpal tunnel syndrome" returned 52 free, full-text review articles on human participants. First 3 results:

Efficacy, safety, and cost of surgical versus nonsurgical treatment for carpal tunnel syndrome: A systematic review and meta-analysis.
 

Author(s): Yi-Ming Ren, Xi-Shan Wang, Zhi-Jian Wei, Bao-You Fan, Wei Lin, Xian-Hu Zhou, Shi-Qing Feng

Journal: Medicine (Baltimore). 2016 Oct;95(40):e4857.

 

Carpal tunnel syndrome (CTS) is a common peripheral nerve entrapment disease. Either surgical or conservative intervention for CTS patients is needed to choose. We conducted this systematic review and meta-analysis to compare the clinical efficacy, safety, and cost of surgical versus ...

Last Updated: 17 Oct 2016

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Effectiveness of low-level laser on carpal tunnel syndrome: A meta-analysis of previously reported randomized trials.
 

Author(s): Zhi-Jun Li, Yao Wang, Hua-Feng Zhang, Xin-Long Ma, Peng Tian, Yuting Huang

Journal: Medicine (Baltimore). 2016 Aug;95(31):e4424.

 

Low-level laser therapy (LLLT) has been applied in the treatment of carpal tunnel syndrome (CTS) for an extended period of time without definitive consensus on its effectiveness. This meta-analysis was conducted to evaluate the effectiveness of low-level laser in the treatment of ...

Last Updated: 6 Aug 2016

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Lipofibromatous hamartoma of the digital branches of the median nerve presenting as carpal tunnel syndrome: A rare case report with review of the literature.
 

Author(s): Ranjan Agrawal, Cheena Garg, Arjun Agarwal, Parbodh Kumar

Journal: Indian J Pathol Microbiol. ;59(1):96-8.

 

Lipofibromatous hamartoma (LFH) is a rare, benign fibrofatty tumor composed of a proliferation of mature adipocytes within peripheral nerves, which form a palpable neurogenic mass. It affects the median nerve in 66-80% of cases, causing pain and sensory and motor deficits in the affected ...

Last Updated: 10 Mar 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Effect of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome
 

Status: Recruiting

Condition Summary: Carpal Tunnel Syndrome

 

Last Updated: 10 Jun 2016

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Assessment of the Effectiveness of Ultrasound-guided Acupuncture in the Management of Carpal Tunnel Syndrome
 

Status: Not yet recruiting

Condition Summary: Carpal Tunnel Syndrome

 

Last Updated: 18 Aug 2016

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Effectiveness of Ultrasound Guided Corticoanesthetic Injection in Carpal Tunnel Syndrome
 

Status: Not yet recruiting

Condition Summary: Carpal Tunnel Syndrome

 

Last Updated: 14 Sep 2016

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