Carpal tunnel syndrome

Common Name(s)

Carpal tunnel syndrome

Carpal tunnel syndrome (CTS) is a condition that causes pain, numbness and tingling in the hand, which may sometimes extend to the wrist and arm as well. The carpal tunnel is a structure that is found at the connection of the wrist and hand. It is formed by a layer of connective tissue that runs over the wrist bones, tendons and nerves going to the hand. CTS occurs when this area becomes tightened and inflamed, causing compression of the nerve.

Roughly 3-6% of adults are affected by CTS, and prevalence increases with age. Individuals with smaller wrists are more likely to be affected by CTS, putting women at greater risk than men. Injury or repetitive motions of the wrist may also cause CTS, such as in individuals who perform repetitive motion such as typing or handling vibrating tools. Other risk factors include conditions of the nervous system, obesity, kidney failure, and thyroid disorders. There are also familial cases of CTS.

Individuals affected by CTS will usually first experience occasional numbness or tingling in the thumb and fingers. Other early symptoms include weakness in the hand and wrist and difficulty grasping items. CTS progresses into more painful and enduring symptoms throughout the wrist region. If left untreated, the nerve and muscle may be permanently damaged. After symptoms are reported, CTS is diagnosed by physical exam, medical imaging, electrical impulse measurements, and other nerve studies.

Treatment for CTS may help prevent symptoms from progressing. Resting and applying ice to the hands may help reduce swelling. Wearing a splint, especially at night, may also help reduce symptoms. Medications, such as anti-inflammatory drugs, may be given as pills or as injections. In severe, long-term cases, surgery may be necessary. If you are experiencing CTS, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Carpal tunnel syndrome" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Carpal tunnel syndrome" returned 537 free, full-text research articles on human participants. First 3 results:

Antioxidant activity of linalool in patients with carpal tunnel syndrome.
 

Author(s): Geun-Hye Seol, Purum Kang, Hui Su Lee, Geun Hee Seol

Journal:

 

Carpal tunnel syndrome (CTS) is a common peripheral neuropathy and ischemic-reperfusion injury. Oxidative stress is considered a major cause of CTS. Linalool, a component of essential oils, has antioxidant activity. This study was designed to determine the effects of linalool inhalation ...

Last Updated: 2 Feb 2016

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Carpal Tunnel Syndrome Associated with Oral Bisphosphonates. A Population-Based Cohort Study.
 

Author(s): Alfonso Carvajal, Luis H Martín Arias, María Sáinz, Antonio Escudero, Inmaculada Fierro, Odile Sauzet, Victoria R Cornelius, Mariam Molokhia

Journal:

 

Bisphosphonates are widely used to prevent osteoporotic fractures. Some severe musculoskeletal reactions have been described with this medication; among them, some cases of carpal tunnel syndrome. Thus, the aim of this study was to explore whether bisphosphonates may be associated ...

Last Updated: 15 Jan 2016

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Assessment of Median Nerve Mobility by Ultrasound Dynamic Imaging for Diagnosing Carpal Tunnel Syndrome.
 

Author(s): Tai-Tzung Kuo, Ming-Ru Lee, Yin-Yin Liao, Jiann-Perng Chen, Yen-Wei Hsu, Chih-Kuang Yeh

Journal:

 

Carpal tunnel syndrome (CTS) is the most common peripheral neuropathy and is characterized by median nerve entrapment at the wrist and the resulting median nerve dysfunction. CTS is diagnosed clinically as the gold standard and confirmed with nerve conduction studies (NCS). Complementing ...

Last Updated: 15 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Carpal tunnel syndrome" returned 49 free, full-text review articles on human participants. First 3 results:

Endoscopic and Open Release Similarly Safe for the Treatment of Carpal Tunnel Syndrome. A Systematic Review and Meta-Analysis.
 

Author(s): Haris S Vasiliadis, Adriani Nikolakopoulou, Ian Shrier, Michael P Lunn, Ruth Brassington, Rob J P Scholten, Georgia Salanti

Journal:

 

The Endoscopic Release of Carpal Tunnel Syndrome (ECTR) is a minimal invasive approach for the treatment of Carpal Tunnel Syndrome. There is scepticism regarding the safety of this technique, based on the assumption that this is a rather "blind" procedure and on the high number of ...

Last Updated: 17 Dec 2015

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Carpal tunnel syndrome and work.
 

Author(s): Lisa Newington, E Clare Harris, Karen Walker-Bone

Journal: Best Pract Res Clin Rheumatol. 2015 Jun;29(3):440-53.

 

Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome, and it frequently presents in working-aged adults. Its mild form causes 'nuisance' symptoms including dysaesthesia and nocturnal waking. At its most severe, CTS can significantly impair motor function ...

Last Updated: 27 Nov 2015

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A Bayesian network meta-analysis: Comparing the clinical effectiveness of local corticosteroid injections using different treatment strategies for carpal tunnel syndrome.
 

Author(s): Po-Cheng Chen, Ching-Hui Chuang, Yu-Kang Tu, Chyi-Huey Bai, Chieh-Feng Chen, Mei- Yun Liaw

Journal:

 

Local corticosteroid injections are commonly used to improve the short-term symptomatic severity and the functional status of the hands affected by carpal tunnel syndrome. We conducted a systematic review and Bayesian network-meta-analysis to compare the clinical effectiveness of ...

Last Updated: 20 Nov 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Carpal Tunnel Syndrome and Amyloid Cardiomyopathy
 

Status: Recruiting

Condition Summary: Amyloidosis; Cardiomyopathy; Transthyretin Amyloidosis; Senile Systemic Amyloidosis; Carpal Tunnel Syndrome

 

Last Updated: 21 Sep 2016

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Treatment of Carpal Tunnel Syndrome With Dynamic Splinting
 

Status: Recruiting

Condition Summary: Carpal Tunnel Syndrome

 

Last Updated: 10 May 2008

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Diacutaneous Fibrolysis on Carpal Tunnel Syndrome
 

Status: Recruiting

Condition Summary: Carpal Tunnel Syndrome

 

Last Updated: 4 May 2016

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