Bronchiectasis

Common Name(s)

Bronchiectasis

Bronchiectasis is a condition in which the tubes that carry air to the lungs slowly lose their ability to clear out mucus due to widening and scarring. As the mucus builds up, bacteria have the opportunity to grow. This bacterial growth leads to repeated, serious lung infections, causing damage to the airways. Over time, the airways can't move enough air in and out of the lungs, which may lead to the body’s vital organs not receiving enough oxygen.

Symptoms of this condition may include long-term (chronic) coughing, coughing up large amounts of mucus, wheezing, chest pain, shortness of breath, clubbing (where the skin beneath the nails becomes thicker), weight loss, and fatigue.

Bronchiectasis has two forms: congenital, which results from a problem with the lung development in a fetus, or acquired, which results from a viral or bacterial infection of the lungs. Lung (pulmonary) conditions including cystic fibrosis, pneumonia, tuberculosis, and COPD have also been known to cause bronchiectasis.

This condition is typically diagnosed when an affected individual expresses their symptoms to the doctor. Using a physical exam, a chest X-ray, and other pulmonary function exams, the doctor can make an official diagnosis. Although there is no cure at this time, there are many treatment options available. The use of antibiotics and mucus-thinning medications can be used to treat infections and help lessen the amount of mucus in the lungs. Bronchodilators, oxygen therapy, and physical therapy have been useful to increase airflow to the lungs. In more serious cases, there are also surgical options available.

Although bronchiectasis is manageable, leaving the condition untreated could result in further lung damage. If you or someone you know is experiencing the symptoms of bronchiectasis, it is important to contact your doctor as soon as possible to discuss the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

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COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

Last Updated: 25 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

Logo
COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

http://www.copdfoundation.org

Last Updated: 25 Mar 2013

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General Resources

Bronchiectasis Research Registry

The Bronchiectasis Research Registry is a consolidated database of non-cystic fibrosis (non-CF) bronchiectasis patients and Nontuberculous Mycobacteria (NTM) patients from multiple clinical institutions.

Uploaded By: COPD Foundation

Updated 21 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchiectasis" returned 542 free, full-text research articles on human participants. First 3 results:

A Randomized Controlled Trial of Atorvastatin in Patients With Bronchiectasis Infected With Pseudomonas Aeruginosa: A Proof of Concept Study.
 

Author(s): Pallavi Bedi, James D Chalmers, Catriona Graham, Andrea Clarke, Samantha Donaldson, Catherine Doherty, John R W Govan, Donald J Davidson, Adriano G Rossi, Adam T Hill

Journal: Chest. 2017 Aug;152(2):368-378.

 

There are no randomized controlled trials of statin therapy in patients with severe bronchiectasis who are chronically infected with Pseudomonas aeruginosa.

Last Updated: 30 May 2017

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Clinical impact of chronic obstructive pulmonary disease on non-cystic fibrosis bronchiectasis. A study on 1,790 patients from the Spanish Bronchiectasis Historical Registry.
 

Author(s): David De la Rosa, Miguel-Angel Martínez-Garcia, Rosa Maria Giron, Montserrat Vendrell, Casilda Olveira, Luis Borderias, Luis Maiz, Antoni Torres, Eva Martinez-Moragon, Olga Rajas, Francisco Casas, Rosa Cordovilla, Javier de Gracia

Journal:

 

Few studies have evaluated the coexistence of bronchiectasis (BE) and chronic obstructive pulmonary disease (COPD) in series of patients diagnosed primarily with BE. The aim of this study was to analyse the characteristics of patients with BE associated with COPD included in the Spanish ...

Last Updated: 25 May 2017

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Comparison of two prognostic scores (BSI and FACED) in a Spanish cohort of adult patients with bronchiectasis and improvement of the FACED predictive capacity for exacerbations.
 

Author(s): Edmundo Rosales-Mayor, Eva Polverino, Laura Raguer, Victoria Alcaraz, Albert Gabarrus, Otavio Ranzani, Rosario Menendez, Antoni Torres

Journal:

 

Bronchiectasis (BE) is a chronic and heterogeneous respiratory disease that requires a multidimensional scoring system to properly assess severity. The aim of this study was to compare the severity stratification by 2 validated scores (BSI and FACED) in a BE cohort and to determine ...

Last Updated: 6 Apr 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchiectasis" returned 39 free, full-text review articles on human participants. First 3 results:

Suspecting non-cystic fibrosis bronchiectasis: What the busy primary care clinician needs to know.
 

Author(s): Diego J Maselli, Bravein Amalakuhan, Holly Keyt, Alejandro A Diaz

Journal: Int. J. Clin. Pract.. 2017 Feb;71(2):.

 

Non-cystic fibrosis bronchiectasis (NCFB) is a chronic, progressive respiratory disorder characterised by irreversibly and abnormally dilated airways, persistent cough, excessive sputum production and recurrent pulmonary infections. In the last several decades, its prevalence has ...

Last Updated: 26 Feb 2017

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Bronchiectasis as a Comorbidity of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.
 

Author(s): Qingxia Du, Jianmin Jin, Xiaofang Liu, Yongchang Sun

Journal:

 

Bronchiectasis revealed by chest computed tomography in COPD patients and its comorbid effect on prognosis have not been addressed by large-sized studies. Understanding the presence of bronchiectasis in COPD is important for future intervention and preventing disease progression.

Last Updated: 16 Mar 2016

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Efficiency and safety of surgical intervention to patients with Non-Cystic Fibrosis bronchiectasis: a meta-analysis.
 

Author(s): Li-Chao Fan, Shuo Liang, Hai-Wen Lu, Ke Fei, Jin-Fu Xu

Journal:

 

No quantitative systematic review was found to report the efficiency and safety of surgical resection in the management of non-cystic fibrosis (non-CF) bronchiectasis. We therefore conducted a meta-analysis to assess the effects of operative intervention to patients with non-CF bronchiectasis. ...

Last Updated: 2 Dec 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Role of Innate Immunity in Non-Cystic Fibrosis Bronchiectasis
 

Status: Recruiting

Condition Summary: Bronchiectasis

 

Last Updated: 7 Sep 2016

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Last Updated: 15 Aug 2016

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Bacteriology and Inflammation in Bronchiectasis
 

Status: Recruiting

Condition Summary: Bronchiectasis

 

Last Updated: 8 Aug 2016

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