Bronchiectasis

Common Name(s)

Bronchiectasis

Bronchiectasis is a condition in which the tubes that carry air to your lungs slowly lose their ability to clear out mucus due to widening and scarring. As the mucus builds up, bacteria begin to grow. This leads to repeated, serious lung infections, causing damage to the airways. Over time, the airways become unable to move enough air into and out of the lungs, which may lead to the body’s vital organs not receiving enough oxygen. Bronchiectasis has two forms: congenital, which results from a problem with the lung development in a fetus, or acquired, which results from an infection of the lungs, such as whooping cough. Though there is no cure, with proper diagnosis and treatment most people maintain a good quality of life.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

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COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

Last Updated: 25 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

Logo
COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

http://www.copdfoundation.org

Last Updated: 25 Mar 2013

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General Resources

Bronchiectasis Research Registry

The Bronchiectasis Research Registry is a consolidated database of non-cystic fibrosis (non-CF) bronchiectasis patients and Nontuberculous Mycobacteria (NTM) patients from multiple clinical institutions.

Uploaded By: COPD Foundation

Updated 21 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchiectasis" returned 347 free, full-text research articles on human participants. First 3 results:

Lung clearance index in adults with non-cystic fibrosis bronchiectasis.
 

Author(s): Sherif Gonem, Alys Scadding, Marcia Soares, Amisha Singapuri, Per Gustafsson, Chandra Ohri, Simon Range, Christopher E Brightling, Ian Pavord, Alex Horsley, Salman Siddiqui

Journal:

 

Lung clearance index (LCI) is a measure of abnormal ventilation distribution derived from the multiple breath inert gas washout (MBW) technique. We aimed to determine the clinical utility of LCI in non-CF bronchiectasis, and to assess two novel MBW parameters that distinguish between ...

Last Updated: 4 Jun 2014

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The short and long term effects of exercise training in non-cystic fibrosis bronchiectasis--a randomised controlled trial.
 

Author(s): Annemarie L Lee, Catherine J Hill, Nola Cecins, Sue Jenkins, Christine F McDonald, Angela T Burge, Linda Rautela, Robert G Stirling, Philip J Thompson, Anne E Holland

Journal:

 

Exercise training is recommended for non-cystic fibrosis (CF) bronchiectasis, but the long-term effects are unclear. This randomised controlled trial aimed to determine the effects of exercise training and review of airway clearance therapy (ACT) on exercise capacity, health related ...

Last Updated: 23 Apr 2014

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Inhaled colistin in patients with bronchiectasis and chronic Pseudomonas aeruginosa infection.
 

Author(s): Charles S Haworth, Juliet E Foweraker, Peter Wilkinson, Robert F Kenyon, Diana Bilton

Journal: Am. J. Respir. Crit. Care Med.. 2014 Apr;189(8):975-82.

 

Chronic infection with Pseudomonas aeruginosa is associated with an increased exacerbation frequency, a more rapid decline in lung function, and increased mortality in patients with bronchiectasis.

Last Updated: 16 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchiectasis" returned 24 free, full-text review articles on human participants. First 3 results:

Bronchiectasis: still a problem.
 

Author(s): Zengli Wang

Journal: Chin. Med. J.. 2014 ;127(1):157-72.

 

The purpose of this descriptive review was to delineate the current knowledge of bronchiectasis in terms of prevalence, burden of disease, pathophysiology, and management.

Last Updated: 3 Jan 2014

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Video-assisted thoracoscopic double lobectomy for bronchiectasis: a case report and literature review.
 

Author(s): Toshiaki Takahashi, Tadaharu Okazaki, Takashi Doi, Hiroyuki Koga, Kenji Suzuki, Geoffrey J Lane, Atsuyuki Yamataka

Journal: Afr J Paediatr Surg. ;10(3):289-91.

 

Although thoracoscopic lobectomy for severe bronchiectasis has been reported in children, this is the first report of double lobectomy of the right middle and lower lobes performed using the video-assisted thoracoscopy in a 9-year-old girl. The post-operative course was uneventful ...

Last Updated: 6 Nov 2013

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New advances in the therapy of non-cystic fibrosis bronchiectasis.
 

Author(s): A Amorim, F Gamboa, P Azevedo

Journal: Rev Port Pneumol. ;19(6):266-75.

 

Non-cystic fibrosis bronchiectasis remains a common and important respiratory disease to date. It is a chronic pathology and consequently the patients usually require continuous treatment. In recent decades therapies that do not have scientific evidence of their benefits have been ...

Last Updated: 11 Nov 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Natural History of Bronchiectasis
 

Status: Recruiting

Condition Summary: Bronchiectasis; Cystic Fibrosis; Autoimmune Disease; Common Variable Immunodeficiency

 

Last Updated: 11 Dec 2014

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Exercise Capacity in Bronchiectasis Resection
 

Status: Recruiting

Condition Summary: Bronchiectasis

 

Last Updated: 29 Dec 2010

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ELTGOL and Bronchiectasis. Respiratory Therapy
 

Status: Recruiting

Condition Summary: Respiratory; Complications, Therapy; Bronchiectasis

 

Last Updated: 16 Apr 2012

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