Bronchiectasis

Common Name(s)

Bronchiectasis

Bronchiectasis is a condition in which the tubes that carry air to the lungs slowly lose their ability to clear out mucus due to widening and scarring. As the mucus builds up, bacteria have the opportunity to grow. This bacterial growth leads to repeated, serious lung infections, causing damage to the airways. Over time, the airways can't move enough air in and out of the lungs, which may lead to the body’s vital organs not receiving enough oxygen.

Symptoms of this condition may include long-term (chronic) coughing, coughing up large amounts of mucus, wheezing, chest pain, shortness of breath, clubbing (where the skin beneath the nails becomes thicker), weight loss, and fatigue.

Bronchiectasis has two forms: congenital, which results from a problem with the lung development in a fetus, or acquired, which results from a viral or bacterial infection of the lungs. Lung (pulmonary) conditions including cystic fibrosis, pneumonia, tuberculosis, and COPD have also been known to cause bronchiectasis.

This condition is typically diagnosed when an affected individual expresses their symptoms to the doctor. Using a physical exam, a chest X-ray, and other pulmonary function exams, the doctor can make an official diagnosis. Although there is no cure at this time, there are many treatment options available. The use of antibiotics and mucus-thinning medications can be used to treat infections and help lessen the amount of mucus in the lungs. Bronchodilators, oxygen therapy, and physical therapy have been useful to increase airflow to the lungs. In more serious cases, there are also surgical options available.

Although bronchiectasis is manageable, leaving the condition untreated could result in further lung damage. If you or someone you know is experiencing the symptoms of bronchiectasis, it is important to contact your doctor as soon as possible to discuss the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

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COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

Last Updated: 25 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

Logo
COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

http://www.copdfoundation.org

Last Updated: 25 Mar 2013

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General Resources

Bronchiectasis Research Registry

The Bronchiectasis Research Registry is a consolidated database of non-cystic fibrosis (non-CF) bronchiectasis patients and Nontuberculous Mycobacteria (NTM) patients from multiple clinical institutions.

Uploaded By: COPD Foundation

Updated 21 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchiectasis" returned 596 free, full-text research articles on human participants. First 3 results:

Effects of exercise on secretion transport, inflammation, and quality of life in patients with noncystic fibrosis bronchiectasis: Protocol for a randomized controlled trial.
 

Author(s): Daniele Oliveira Dos Santos, Hugo Celso Dutra de Souza, José Antônio Baddini-Martinez, Ercy Mara Cipulo Ramos, Ada Clarice Gastaldi

Journal: Medicine (Baltimore). 2018 Feb;97(7):e9768.

 

Bronchiectasis is characterized by pathological and irreversible bronchial dilatation caused by the inefficient mucus and microorganism clearance and progression of inflammatory processes. The most frequent characteristic is the increase in bronchial mucus production resulting in ...

Last Updated: 31 Dec 1969

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Could Chinese herbs accelerate the resolution of reversible bronchiectasis in adults?: A case report.
 

Author(s): Hai-Yan Li, Qi Guo

Journal: Medicine (Baltimore). 2017 Dec;96(50):e8883.

 

The classic definition of bronchiectasis is of permanent bronchial dilatation. Therefore, bronchiectasis is generally considered irreversible in the adult population.

Last Updated: 31 Dec 1969

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The relationship of SSRI and SNRI usage with interstitial lung disease and bronchiectasis in an elderly population: a case-control study.
 

Author(s): Ted Rosenberg, Rory Lattimer, Patrick Montgomery, Christian Wiens, Liran Levy

Journal:

 

The association between interstitial lung disease (ILD) and selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors (SSRI/SNRI) has been previously described in published case reports. However, its prevalence may be more common than expected. We examined ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchiectasis" returned 49 free, full-text review articles on human participants. First 3 results:

Diagnosis and management of bronchiectasis.
 

Author(s): Maeve P Smith

Journal: CMAJ. 2017 06;189(24):E828-E835.

 

KEY POINTS Following a diagnosis of bronchiectasis, it is important to investigate for an underlying cause. Goals of management are to suppress airway infection and inflammation, to improve symptoms and health-related quality of life. There are now validated scoring tools to help ...

Last Updated: 31 Dec 1969

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Bronchiectasis in COPD patients: more than a comorbidity?
 

Author(s): Miguel Angel Martinez-Garcia, Marc Miravitlles

Journal:

 

Computed tomography scan images have been used to identify different radiological COPD phenotypes based on the presence and severity of emphysema, bronchial wall thickening, and bronchiectasis. Bronchiectasis is defined as an abnormal dilation of the bronchi, usually as a result of ...

Last Updated: 31 Dec 1969

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[Management of adult bronchiectasis].
 

Author(s): G Tassart, T Pieters, S Gohy

Journal: Rev Med Liege. 2016 Oct;71(10):440-448.

 

Non-cystic fibrosis bronchiectasis has been the subject of renewed interest over recent years. It is usually part of the evolutionary process of many infectious, autoimmune, genetic, developmental or allergic diseases. Its presentation and prognosis are heterogeneous and it causes ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effects of Traditional Chinese Medicine on Bronchiectasis Patients
 

Status: Not yet recruiting

Condition Summary: Bronchiectasis

 

Last Updated: 17 Feb 2018

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Last Updated: 15 Aug 2016

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Role of Innate Immunity in Non-Cystic Fibrosis Bronchiectasis
 

Status: Recruiting

Condition Summary: Bronchiectasis

 

Last Updated: 7 Sep 2016

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