Bronchiectasis

Common Name(s)

Bronchiectasis

Bronchiectasis is a condition in which the tubes that carry air to your lungs slowly lose their ability to clear out mucus due to widening and scarring. As the mucus builds up, bacteria begin to grow. This leads to repeated, serious lung infections, causing damage to the airways. Over time, the airways become unable to move enough air into and out of the lungs, which may lead to the body’s vital organs not receiving enough oxygen. Bronchiectasis has two forms: congenital, which results from a problem with the lung development in a fetus, or acquired, which results from an infection of the lungs, such as whooping cough. Though there is no cure, with proper diagnosis and treatment most people maintain a good quality of life.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

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COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

Last Updated: 25 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

Logo
COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

http://www.copdfoundation.org

Last Updated: 25 Mar 2013

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General Resources

Bronchiectasis Research Registry

The Bronchiectasis Research Registry is a consolidated database of non-cystic fibrosis (non-CF) bronchiectasis patients and Nontuberculous Mycobacteria (NTM) patients from multiple clinical institutions.

Uploaded By: COPD Foundation

Updated 21 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchiectasis" returned 335 free, full-text research articles on human participants. First 3 results:

Mannose-binding lectin deficiency and disease severity in non-cystic fibrosis bronchiectasis: a prospective study.
 

Author(s): James D Chalmers, Brian J McHugh, Catherine Doherty, Maeve P Smith, John R Govan, David C Kilpatrick, Adam T Hill

Journal: Lancet Respir Med. 2013 May;1(3):224-32.

 

Mannose-binding lectin (MBL) is a key component of innate immunity. MBL deficiency is common (10-30% of the general population depending on the definition used) and has been associated with disease progression in cystic fibrosis. We aimed to assess the effect of MBL deficiency on ...

Last Updated: 16 Jan 2014

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Development of allergic bronchopulmonary aspergillosis with central bronchiectasis over a 10-year period: the need to recheck allergen sensitization.
 

Author(s): Yoshiko Yoshida, Toshihiro Shirai, Masashi Mikamo, Yuichiro Shishido, Takefumi Akita, Satoru Morita, Kazuhiro Asada, Masato Fujii, Takafumi Suda

Journal: Intern. Med.. 2013 ;52(18):2135-8.

 

A 55-year-old woman visited our hospital for an investigation of central bronchiectasis, mucoid impaction and infiltrative shadows on chest CT. She had a 10-year history of bronchial asthma; however, her adherence to treatment was poor. Based on the presence of peripheral blood eosinophilia ...

Last Updated: 17 Sep 2013

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Presence of anxiety and depression in patients with bronchiectasis unrelated to cystic fibrosis.
 

Author(s): Rosa María Girón Moreno, Gilda Fernandes Vasconcelos, Carolina Cisneros, Rosa Mar Gómez-Punter, Gonzalo Segrelles Calvo, Julio Ancochea

Journal: Arch. Bronconeumol.. 2013 Oct;49(10):415-20.

 

Patients with chronic bronchiectasis (BQ) may suffer from psychological disorders. The objective of this study was to assess the presence of anxiety and depression in patients from a specialised BQ Unit, using validated questionnaires.

Last Updated: 1 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchiectasis" returned 22 free, full-text review articles on human participants. First 3 results:

Bronchiectasis: still a problem.
 

Author(s): Zengli Wang

Journal: Chin. Med. J.. 2014 ;127(1):157-72.

 

The purpose of this descriptive review was to delineate the current knowledge of bronchiectasis in terms of prevalence, burden of disease, pathophysiology, and management.

Last Updated: 3 Jan 2014

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Video-assisted thoracoscopic double lobectomy for bronchiectasis: a case report and literature review.
 

Author(s): Toshiaki Takahashi, Tadaharu Okazaki, Takashi Doi, Hiroyuki Koga, Kenji Suzuki, Geoffrey J Lane, Atsuyuki Yamataka

Journal: Afr J Paediatr Surg. ;10(3):289-91.

 

Although thoracoscopic lobectomy for severe bronchiectasis has been reported in children, this is the first report of double lobectomy of the right middle and lower lobes performed using the video-assisted thoracoscopy in a 9-year-old girl. The post-operative course was uneventful ...

Last Updated: 6 Nov 2013

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Immune mechanisms and the impact of the disrupted lung microbiome in chronic bacterial lung infection and bronchiectasis.
 

Author(s): R J Boyton, C J Reynolds, K J Quigley, D M Altmann

Journal: Clin. Exp. Immunol.. 2013 Feb;171(2):117-23.

 

Recent studies analysing immunogenetics and immune mechanisms controlling susceptibility to chronic bacterial infection in bronchiectasis implicate dysregulated immunity in conjunction with chronic bacterial infection. Bronchiectasis is a structural pathological end-point with many ...

Last Updated: 4 Jan 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Natural History of Bronchiectasis
 

Status: Recruiting

Condition Summary: Bronchiectasis; Cystic Fibrosis; Autoimmune Disease; Common Variable Immunodeficiency

 

Last Updated: 24 Jun 2014

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Cross-sectional Characterization of Idiopathic Bronchiectasis
 

Status: Recruiting

Condition Summary: Idiopathic Bronchiectasis; Nontuberculous Mycobacterium (NTM) Infection

 

Last Updated: 24 Jun 2014

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Metabolomic Analysis of Exhaled Breath Condensates in Patients With COPD and Bronchiectasis
 

Status: Recruiting

Condition Summary: COPD; Bronchiectasis

 

Last Updated: 4 Aug 2011

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