Bronchiectasis

Common Name(s)

Bronchiectasis

Bronchiectasis is a condition in which the tubes that carry air to your lungs slowly lose their ability to clear out mucus due to widening and scarring. As the mucus builds up, bacteria begin to grow. This leads to repeated, serious lung infections, causing damage to the airways. Over time, the airways become unable to move enough air into and out of the lungs, which may lead to the body’s vital organs not receiving enough oxygen. Bronchiectasis has two forms: congenital, which results from a problem with the lung development in a fetus, or acquired, which results from an infection of the lungs, such as whooping cough. Though there is no cure, with proper diagnosis and treatment most people maintain a good quality of life.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

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COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

Last Updated: 25 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiectasis" for support, advocacy or research.

Logo
COPD Foundation

The mission of the COPD Foundation is to develop and support programs which improve the quality of life through research, education, early diagnosis, and enhanced therapy for persons whose lives are impacted by Chronic Obstructive Pulmonary Disease.

http://www.copdfoundation.org

Last Updated: 25 Mar 2013

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General Resources

Bronchiectasis Research Registry

The Bronchiectasis Research Registry is a consolidated database of non-cystic fibrosis (non-CF) bronchiectasis patients and Nontuberculous Mycobacteria (NTM) patients from multiple clinical institutions.

Uploaded By: COPD Foundation

Updated 21 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchiectasis" returned 353 free, full-text research articles on human participants. First 3 results:

Treatment adherence and health outcomes in patients with bronchiectasis.
 

Author(s): Amanda R McCullough, Michael M Tunney, Alexandra L Quittner, J Stuart Elborn, Judy M Bradley, Carmel M Hughes

Journal:

 

We aimed to determine adherence to inhaled antibiotics, other respiratory medicines and airway clearance and to determine the association between adherence to these treatments and health outcomes (pulmonary exacerbations, lung function and Quality of Life Questionnaire-Bronchiectasis ...

Last Updated: 11 Jul 2014

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Lung clearance index in adults with non-cystic fibrosis bronchiectasis.
 

Author(s): Sherif Gonem, Alys Scadding, Marcia Soares, Amisha Singapuri, Per Gustafsson, Chandra Ohri, Simon Range, Christopher E Brightling, Ian Pavord, Alex Horsley, Salman Siddiqui

Journal:

 

Lung clearance index (LCI) is a measure of abnormal ventilation distribution derived from the multiple breath inert gas washout (MBW) technique. We aimed to determine the clinical utility of LCI in non-CF bronchiectasis, and to assess two novel MBW parameters that distinguish between ...

Last Updated: 4 Jun 2014

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To investigate the prevention of OM-85 on bronchiectasis exacerbations (iPROBE) in Chinese patients: study protocol for a randomized controlled trial.
 

Author(s): Jinming Gao, Xiang Gao, Lingfei Kong

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Non-cystic fibrosis bronchiectasis is characterized by the irreversible dilatation of the medium-sized bronchi as a result of airway injury from recurrent or chronic inflammation and lower respiratory tract infections. Bronchiectasis airways are commonly colonized with bacterial species. ...

Last Updated: 3 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchiectasis" returned 24 free, full-text review articles on human participants. First 3 results:

Macrolide therapy in adults and children with non-cystic fibrosis bronchiectasis: a systematic review and meta-analysis.
 

Author(s): Yong-Hua Gao, Wei-Jie Guan, Gang Xu, Yan Tang, Yang Gao, Zhi-Ya Lin, Zhi-Min Lin, Nan-Shan Zhong, Rong-Chang Chen

Journal:

 

A systematic review and meta-analysis was conducted to evaluate the efficacy and safety of macrolide therapy in adults and children with bronchiectasis.

Last Updated: 7 Mar 2014

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Long-term macrolides for non-cystic fibrosis bronchiectasis: a systematic review and meta-analysis.
 

Author(s): Qibiao Wu, Weixing Shen, Haibo Cheng, Xiqiao Zhou

Journal: Respirology. 2014 Apr;19(3):321-9.

 

Long-term macrolides are increasingly being prescribed for stable bronchiectasis. This meta-analysis assessed the clinical effect of this treatment in bronchiectasis. A systematic review and meta-analysis were carried out. All randomized, controlled trials (RCT) comparing long-term ...

Last Updated: 13 Mar 2014

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Video-assisted thoracoscopic double lobectomy for bronchiectasis: a case report and literature review.
 

Author(s): Toshiaki Takahashi, Tadaharu Okazaki, Takashi Doi, Hiroyuki Koga, Kenji Suzuki, Geoffrey J Lane, Atsuyuki Yamataka

Journal: Afr J Paediatr Surg. ;10(3):289-91.

 

Although thoracoscopic lobectomy for severe bronchiectasis has been reported in children, this is the first report of double lobectomy of the right middle and lower lobes performed using the video-assisted thoracoscopy in a 9-year-old girl. The post-operative course was uneventful ...

Last Updated: 6 Nov 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Natural History of Bronchiectasis
 

Status: Recruiting

Condition Summary: Bronchiectasis; Cystic Fibrosis; Autoimmune Disease; Common Variable Immunodeficiency

 

Last Updated: 24 Feb 2015

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Exercise Capacity in Bronchiectasis Resection
 

Status: Recruiting

Condition Summary: Bronchiectasis

 

Last Updated: 29 Dec 2010

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ELTGOL and Bronchiectasis. Respiratory Therapy
 

Status: Recruiting

Condition Summary: Respiratory; Complications, Therapy; Bronchiectasis

 

Last Updated: 16 Apr 2012

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