Bladder cancer

Common Name(s)

Bladder cancer

Bladder cancer is a type of cancer that begins in the cells of the bladder, the organ that stores urine. Those affected by bladder cancer may have blood in their urine (hematuria), causing the urine to appear dark yellow, red, or brown. Other symptoms of bladder cancer include a frequent need to urinate, painful urination, and pelvic or back pain.

Bladder cancer occurs when cells in the bladder develop mutations that result in the cells dividing rapidly and resisting death. Those cells form a tumor. Although the cause of bladder cancer is not always known, bladder cancer has been linked to smoking, parasitic infection, and exposure to radiation and chemicals. Other risk factors include previous cancer treatment, taking certain medications for diabetes, repeated bladder infections, and a personal or family history of cancer. White males are more likely to develop bladder cancer than women and individuals of other races. Bladder cancer occurs most often among older individuals.

Bladder cancer may be diagnosed through several methods. A doctor may perform a cystoscopy, a procedure in which a thin tube with a lens is inserted through the urethra to view the bladder lining. During the cystoscopy, a cell sample may be collected using a tool passed through the tube in a procedure called a biopsy. Additionally, a urine sample may be analyzed under a microscope for cancer cells. Imaging tests such as X-ray and computerized tomography (CT) scans can also be used to detect bladder cancer. After diagnosis, a doctor may perform additional tests to determine the stage of cancer.

Treatments for bladder cancer include surgery, immunotherapy, chemotherapy, and, occasionally, radiation therapy. If you have been diagnosed with bladder cancer, talk to your doctor about the most current treatment options. Support groups are available for more resources and information and can connect you with others also diagnosed with bladder cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bladder cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Bladder Cancer Advocacy Network

To increase public awareness about bladder cancer; to advance bladder cancer research; and to provide educational and support services for the bladder cancer community.

Last Updated: 29 Nov 2013

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Bladder Cancer Support UK

A charity supporting people diagnosed with bladder cancer together with their caters, family and friends. Providing information, increasing awareness and funding research.

Last Updated: 18 Mar 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bladder cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Bladder Cancer Advocacy Network

To increase public awareness about bladder cancer; to advance bladder cancer research; and to provide educational and support services for the bladder cancer community.

http://www.bcan.org/

Last Updated: 29 Nov 2013

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Bladder Cancer Support UK

A charity supporting people diagnosed with bladder cancer together with their caters, family and friends. Providing information, increasing awareness and funding research.

Last Updated: 18 Mar 2013

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bladder cancer" returned 3433 free, full-text research articles on human participants. First 3 results:

Association between interleukin-22 genetic polymorphisms and bladder cancer risk.
 

Author(s): Tao Zhao, XiaoHou Wu, JiaJi Liu

Journal: Clinics (Sao Paulo). 2015 Oct;70(10):686-90.

 

The cytokine interleukin-22 (IL-22), which is produced by T cells and natural killer cells, is associated with tumorigenesis and tumor progression in cancers. However, the role of IL-22 in bladder cancer has not been investigated.

Last Updated: 24 Nov 2015

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Chronic Indwelling Urinary Catheter Increase the Risk of Bladder Cancer, Even in Patients Without Spinal Cord Injury.
 

Author(s): Chung-Han Ho, Kuan-Chin Sung, Sher-Wei Lim, Chien-Hwa Liao, Fu-Wen Liang, Jhi-Joung Wang, Chia-Chun Wu

Journal: Medicine (Baltimore). 2015 Oct;94(43):e1736.

 

Chronic indwelling urinary catheters (CIDCs) are known as a risk factor for bladder cancer in patients with spinal cord injury (SCI). This study examined the potential risk of bladder cancer from CIDCs in patients without SCI.The National Health Insurance Research Database in Taiwan ...

Last Updated: 30 Oct 2015

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Modified Glasgow Prognostic Score is Associated With Risk of Recurrence in Bladder Cancer Patients After Radical Cystectomy: A Multicenter Experience.
 

Author(s): Matteo Ferro, Ottavio De Cobelli, Carlo Buonerba, Giuseppe Di Lorenzo, Marco Capece, Dario Bruzzese, Riccardo Autorino, Danilo Bottero, Antonio Cioffi, Deliu Victor Matei, Michele Caraglia, Marco Borghesi, Ettore De Berardinis, Gian Maria Busetto, Riccardo Giovannone, Giuseppe Lucarelli, Pasquale Ditonno, Sisto Perdonà, Pierluigi Bove, Luigi Castaldo, Rodolfo Hurle, Gennaro Musi, Antonio Brescia, Michele Olivieri, Amelia Cimmino, Vincenzo Altieri, Rocco Damiano, Francesco Cantiello, Vincenzo Serretta, Sabino De Placido, Vincenzo Mirone, Guru Sonpavde, Daniela Terracciano

Journal: Medicine (Baltimore). 2015 Oct;94(42):e1861.

 

Recently, many studies explored the role of inflammation parameters in the prognosis of urinary cancers, but the results were not consistent. The modified Glasgow Prognostic Score (mGPS), a systemic inflammation marker, is a prognostic marker in various types of cancers. The aim of ...

Last Updated: 27 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bladder cancer" returned 353 free, full-text review articles on human participants. First 3 results:

Low-Dose Versus Standard Dose of Bacillus Calmette-Guerin in the Treatment of Nonmuscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis.
 

Author(s): Shuxiong Zeng, Xiaowen Yu, Chong Ma, Zhensheng Zhang, Ruixiang Song, Xin Chen, Yinghao Sun, Chuanliang Xu

Journal: Medicine (Baltimore). 2015 Dec;94(49):e2176.

 

Whether low-dose Bacillus Calmette-Guerin (BCG) treatment can reduce the side effects while maintaining efficacy for patients with nonmuscle invasive bladder cancer (NMIBC) is controversial.To investigate whether low-dose BCG treatment can reduce the side effects while maintaining ...

Last Updated: 15 Dec 2015

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Evaluating Evidence for Association of Human Bladder Cancer with Drinking-Water Chlorination Disinfection By-Products.
 

Author(s): Steve E Hrudey, Lorraine C Backer, Andrew R Humpage, Stuart W Krasner, Dominique S Michaud, Lee E Moore, Philip C Singer, Benjamin D Stanford

Journal: J Toxicol Environ Health B Crit Rev. 2015 ;18(5):213-41.

 

Exposure to chlorination disinfection by-products (CxDBPs) is prevalent in populations using chlorination-based methods to disinfect public water supplies. Multifaceted research has been directed for decades to identify, characterize, and understand the toxicology of these compounds, ...

Last Updated: 27 Oct 2015

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[The role of oxidative stress in bladder cancer].
 

Author(s): Ewa Sawicka, Agnieszka Lisowska, Paweł Kowal, Anna Długosz

Journal:

 

The review of the knowledge concerning the impact of oxidative and nitrosative stress on signaling pathways and transcription factors involved in the formation of bladder cancer was prepared. In the industrialized countries, bladder cancer is the fourth most frequently occurring malignant ...

Last Updated: 24 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Adjuvant Radiation for High Risk Bladder Cancer
 

Status: Recruiting

Condition Summary: Bladder Cancer; Squamous Cell Carcinoma of the Bladder; Stage III Bladder Cancer; Stage IV Bladder Cancer; Transitional Cell Carcinoma of the Bladder

 

Last Updated: 11 Mar 2016

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Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer
 

Status: Recruiting

Condition Summary: Recurrent Bladder Carcinoma; Stage II Bladder Cancer; Stage III Bladder Cancer; Stage IV Bladder Cancer

 

Last Updated: 26 Apr 2016

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Standard Surgery or Minimal-Access Surgery in Treating Patients With Bladder Cancer
 

Status: Recruiting

Condition Summary: Bladder Cancer

 

Last Updated: 31 Mar 2011

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