Bladder cancer

Common Name(s)

Bladder cancer

Bladder cancer is a type of cancer that begins in the cells of the bladder, the organ that stores urine. Those affected by bladder cancer may have blood in their urine (hematuria), causing the urine to appear dark yellow, red, or brown. Other symptoms of bladder cancer include a frequent need to urinate, painful urination, and pelvic or back pain.

Bladder cancer occurs when cells in the bladder develop mutations that result in the cells dividing rapidly and resisting death. Those cells form a tumor. Although the cause of bladder cancer is not always known, bladder cancer has been linked to smoking, parasitic infection, and exposure to radiation and chemicals. Other risk factors include previous cancer treatment, taking certain medications for diabetes, repeated bladder infections, and a personal or family history of cancer. White males are more likely to develop bladder cancer than women and individuals of other races. Bladder cancer occurs most often among older individuals.

Bladder cancer may be diagnosed through several methods. A doctor may perform a cystoscopy, a procedure in which a thin tube with a lens is inserted through the urethra to view the bladder lining. During the cystoscopy, a cell sample may be collected using a tool passed through the tube in a procedure called a biopsy. Additionally, a urine sample may be analyzed under a microscope for cancer cells. Imaging tests such as X-ray and computerized tomography (CT) scans can also be used to detect bladder cancer. After diagnosis, a doctor may perform additional tests to determine the stage of cancer.

Treatments for bladder cancer include surgery, immunotherapy, chemotherapy, and, occasionally, radiation therapy. If you have been diagnosed with bladder cancer, talk to your doctor about the most current treatment options. Support groups are available for more resources and information and can connect you with others also diagnosed with bladder cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bladder cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Bladder Cancer Advocacy Network

To increase public awareness about bladder cancer; to advance bladder cancer research; and to provide educational and support services for the bladder cancer community.

Last Updated: 29 Nov 2013

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Bladder Cancer Support UK

A charity supporting people diagnosed with bladder cancer together with their caters, family and friends. Providing information, increasing awareness and funding research.

Last Updated: 18 Mar 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bladder cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Bladder Cancer Advocacy Network

To increase public awareness about bladder cancer; to advance bladder cancer research; and to provide educational and support services for the bladder cancer community.

http://www.bcan.org/

Last Updated: 29 Nov 2013

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Bladder Cancer Support UK

A charity supporting people diagnosed with bladder cancer together with their caters, family and friends. Providing information, increasing awareness and funding research.

Last Updated: 18 Mar 2013

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bladder cancer" returned 4136 free, full-text research articles on human participants. First 3 results:

EORTC risk tables are more suitable for Chinese patients with nonmuscle-invasive bladder cancer than AUA risk stratification.
 

Author(s): Hui Wang, Weihong Ding, Guangliang Jiang, Yuancheng Gou, Chuanyu Sun, Zhongqing Chen, Ke Xu, Guowei Xia

Journal: Medicine (Baltimore). 2018 Sep;97(36):e12006.

 

Patients with non-muscle-invasive bladder cancer (NMIBC) need accurate estimations of the risk of recurrence and progression. Physicians can offer individualized therapy after identifying high-risk tumors. In our study, we compared the applicability of European Organization for Research ...

Last Updated: 31 Dec 1969

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Integrated analysis of a competing endogenous RNA network reveals key lncRNAs as potential prognostic biomarkers for human bladder cancer.
 

Author(s): Naiqiang Zhu, Jingyi Hou, Yuanhao Wu, Jinxin Liu, Geng Li, Wenjia Zhao, Guiyun Ma, Bin Chen, Youxin Song

Journal: Medicine (Baltimore). 2018 Aug;97(35):e11887.

 

Human bladder cancer (BCa) is one of the most commonly diagnosed malignancies worldwide. It has high recurrence rates and low-grade malignancy, thus representing an important public health concern. An increasing number of studies suggest that long-noncoding RNAs (lncRNAs) play important ...

Last Updated: 31 Dec 1969

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CDCA8 expression and its clinical relevance in patients with bladder cancer.
 

Author(s): Yaqiong Bi, Song Chen, Jiazhi Jiang, Jie Yao, Gang Wang, Qiang Zhou, Sheng Li

Journal: Medicine (Baltimore). 2018 Aug;97(34):e11899.

 

Cell division cycle associated 8 (CDCA8) overexpression is detected in various malignant tumors and closely associated with tumor growth. However, the correlations of CDCA8 expression with clinicopathological factors and prognosis of bladder cancer (BC) remain unclear. The purpose ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bladder cancer" returned 444 free, full-text review articles on human participants. First 3 results:

Association of metformin intake with bladder cancer risk and oncologic outcomes in type 2 diabetes mellitus patients: A systematic review and meta-analysis.
 

Author(s): Jiao Hu, Jin-Bo Chen, Yu Cui, Ye-Wen Zhu, Wen-Biao Ren, Xu Zhou, Long-Fei Liu, He-Qun Chen, Xiong-Bing Zu

Journal: Medicine (Baltimore). 2018 Jul;97(30):e11596.

 

Recent clinical trials indicated that metformin intake might play a protective role in the incidence and oncologic outcomes of various cancers. However, its protective effect on bladder cancer remains uncertain.

Last Updated: 31 Dec 1969

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Biomarkers in Urachal Cancer and Adenocarcinomas in the Bladder: A Comprehensive Review Supplemented by Own Data.
 

Author(s): Henning Reis, Ulrich Krafft, Christian Niedworok, Orsolya Módos, Thomas Herold, Mark Behrendt, Hikmat Al-Ahmadie, Boris Hadaschik, Peter Nyirady, Tibor Szarvas

Journal:

 

Urachal cancer (UrC) is a rare but aggressive cancer. Due to overlapping histomorphology, discrimination of urachal from primary bladder adenocarcinomas (PBAC) and adenocarcinomas secondarily involving the bladder (particularly colorectal adenocarcinomas, CRC) can be challenging. ...

Last Updated: 31 Dec 1969

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Effectiveness of urine fibronectin as a non-invasive diagnostic biomarker in bladder cancer patients: a systematic review and meta-analysis.
 

Author(s): Fan Dong, Yifan Shen, Tianyuan Xu, Xianjin Wang, Fengbin Gao, Shan Zhong, Shanwen Chen, Zhoujun Shen

Journal:

 

Previous researches pointed out that the measurement of urine fibronectin (Fn) could be a potential diagnostic test for bladder cancer (BCa). We conducted this meta-analysis to fully assess the diagnostic value of urine Fn for BCa detection.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Biomarker Identification for Bladder Cancer Patients
 

Status: Recruiting

Condition Summary: Bladder Cancer

 

Last Updated: 12 Apr 2017

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Pembrolizumab With Chemoradiotherapy as Treatment for Muscle Invasive Bladder Cancer
 

Status: Recruiting

Condition Summary: Bladder Cancer

 

Last Updated: 7 Feb 2018

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Celecoxib With Chemotherapy in Localized, Muscle-Invasive Bladder Cancer
 

Status: Recruiting

Condition Summary: Bladder Cancer

 

Last Updated: 15 Aug 2018

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