Bladder cancer

Common Name(s)

Bladder cancer

Bladder cancer is a type of cancer that begins in the cells of the bladder, the organ that stores urine. Those affected by bladder cancer may have blood in their urine (hematuria), causing the urine to appear dark yellow, red, or brown. Other symptoms of bladder cancer include a frequent need to urinate, painful urination, and pelvic or back pain.

Bladder cancer occurs when cells in the bladder develop mutations that result in the cells dividing rapidly and resisting death. Those cells form a tumor. Although the cause of bladder cancer is not always known, bladder cancer has been linked to smoking, parasitic infection, and exposure to radiation and chemicals. Other risk factors include previous cancer treatment, taking certain medications for diabetes, repeated bladder infections, and a personal or family history of cancer. White males are more likely to develop bladder cancer than women and individuals of other races. Bladder cancer occurs most often among older individuals.

Bladder cancer may be diagnosed through several methods. A doctor may perform a cystoscopy, a procedure in which a thin tube with a lens is inserted through the urethra to view the bladder lining. During the cystoscopy, a cell sample may be collected using a tool passed through the tube in a procedure called a biopsy. Additionally, a urine sample may be analyzed under a microscope for cancer cells. Imaging tests such as X-ray and computerized tomography (CT) scans can also be used to detect bladder cancer. After diagnosis, a doctor may perform additional tests to determine the stage of cancer.

Treatments for bladder cancer include surgery, immunotherapy, chemotherapy, and, occasionally, radiation therapy. If you have been diagnosed with bladder cancer, talk to your doctor about the most current treatment options. Support groups are available for more resources and information and can connect you with others also diagnosed with bladder cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bladder cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Bladder Cancer Advocacy Network

To increase public awareness about bladder cancer; to advance bladder cancer research; and to provide educational and support services for the bladder cancer community.

Last Updated: 29 Nov 2013

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Bladder Cancer Support UK

A charity supporting people diagnosed with bladder cancer together with their caters, family and friends. Providing information, increasing awareness and funding research.

Last Updated: 18 Mar 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bladder cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Bladder Cancer Advocacy Network

To increase public awareness about bladder cancer; to advance bladder cancer research; and to provide educational and support services for the bladder cancer community.

http://www.bcan.org/

Last Updated: 29 Nov 2013

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Bladder Cancer Support UK

A charity supporting people diagnosed with bladder cancer together with their caters, family and friends. Providing information, increasing awareness and funding research.

Last Updated: 18 Mar 2013

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bladder cancer" returned 3474 free, full-text research articles on human participants. First 3 results:

Complete Response and Fatigue Improvement With the Combined Use of Cyclophosphamide and Quercetin in a Patient With Metastatic Bladder Cancer: A Case Report.
 

Author(s): Giuseppe Di Lorenzo, Martina Pagliuca, Teresa Perillo, Aquilino Zarrella, Antonio Verde, Sabino De Placido, Carlo Buonerba

Journal: Medicine (Baltimore). 2016 Feb;95(5):e2598.

 

Bladder cancer is a major cause of cancer-related mortality, with an estimated 74,000 new cases and 16,000 deaths in the United States in 2015. In patients with metastatic disease, vinflunine and taxanes are the most widely used chemotherapy agents in the second-line setting after ...

Last Updated: 5 Feb 2016

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Clinical significance of serum and urinary HER2/neu protein levels in primary non-muscle invasive bladder cancer.
 

Author(s): Ozgur Arikan, Asýf Yýldýrým, Banu Ýsbilen, Cengiz Canakci, Gokhan Atýs, Cenk Gurbuz, Bulent Erol, Ferruh Kemal Ýsman, Seyma Ozkanli, Turhan Caskurlu

Journal: Int Braz J Urol. ;41(6):1080-7.

 

We aimed to compare serum and urinary HER2/neu levels between healthy control group and patients with non-muscle invasive bladder cancer. Additionally, we evaluated relationship of HER2/neu levels with tumor stage, grade, recurrence and progression.

Last Updated: 8 Jan 2016

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Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer.
 

Author(s): Silvia Pineda, Francisco X Real, Manolis Kogevinas, Alfredo Carrato, Stephen J Chanock, Núria Malats, Kristel Van Steen

Journal:

 

Omics data integration is becoming necessary to investigate the genomic mechanisms involved in complex diseases. During the integration process, many challenges arise such as data heterogeneity, the smaller number of individuals in comparison to the number of parameters, multicollinearity, ...

Last Updated: 9 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bladder cancer" returned 358 free, full-text review articles on human participants. First 3 results:

Combination of Intravesical Chemotherapy and Bacillus Calmette-Guerin Versus Bacillus Calmette-Guerin Monotherapy in Intermediate- and High-risk Nonmuscle Invasive Bladder Cancer: A Systematic Review and Meta-analysis.
 

Author(s): Jianfeng Cui, Wenbo Wang, Shouzhen Chen, Pengxiang Chen, Yue Yang, Yunliang Guo, Yaofeng Zhu, Fan Chen, Benkang Shi

Journal: Medicine (Baltimore). 2016 Jan;95(3):e2572.

 

Urothelial carcinoma of the bladder has become a major cause of morbidity, mortality, and health-related costs. There is still no standard instillation therapy against bladder cancer. A meta-analysis was conducted to evaluate the efficacy and toxicity of adding chemotherapy to Bacillus ...

Last Updated: 28 Jan 2016

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Rationale and Early Experience with Prophylactic Placement of Mesh to Prevent Parastomal Hernia Formation after Ileal Conduit Urinary Diversion and Cystectomy for Bladder Cancer.
 

Author(s): Timothy F Donahue, Eugene K Cha, Bernard H Bochner

Journal: Curr Urol Rep. 2016 Feb;17(2):9.

 

Parastomal hernias (PH) represent a clinically significant problem for many patients after radical cystectomy and ileal conduit diversion. The prevalence may be as high as 60% and in some series, up to 30% of patients require surgical intervention due to the complications of pain, ...

Last Updated: 13 Jan 2016

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Low-Dose Versus Standard Dose of Bacillus Calmette-Guerin in the Treatment of Nonmuscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis.
 

Author(s): Shuxiong Zeng, Xiaowen Yu, Chong Ma, Zhensheng Zhang, Ruixiang Song, Xin Chen, Yinghao Sun, Chuanliang Xu

Journal: Medicine (Baltimore). 2015 Dec;94(49):e2176.

 

Whether low-dose Bacillus Calmette-Guerin (BCG) treatment can reduce the side effects while maintaining efficacy for patients with nonmuscle invasive bladder cancer (NMIBC) is controversial.To investigate whether low-dose BCG treatment can reduce the side effects while maintaining ...

Last Updated: 15 Dec 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Adjuvant Radiation for High Risk Bladder Cancer
 

Status: Recruiting

Condition Summary: Bladder Cancer; Squamous Cell Carcinoma of the Bladder; Stage III Bladder Cancer; Stage IV Bladder Cancer; Transitional Cell Carcinoma of the Bladder

 

Last Updated: 11 Mar 2016

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Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer
 

Status: Recruiting

Condition Summary: Recurrent Bladder Carcinoma; Stage II Bladder Cancer; Stage III Bladder Cancer; Stage IV Bladder Cancer

 

Last Updated: 26 Apr 2016

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Standard Surgery or Minimal-Access Surgery in Treating Patients With Bladder Cancer
 

Status: Recruiting

Condition Summary: Bladder Cancer

 

Last Updated: 31 Mar 2011

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