Behcet's disease

Common Name(s)

Behcet's disease, Behcet disease

Behçet’s disease is a rare condition that causes inflammation in blood vessels throughout the body. Inflammation is characterized by redness, swelling and pain and is part of our normal immune response when injured or fighting infection. However, sometimes inflammation may be long term and cause problems. The inflammation caused by Behçet’s disease may lead to numerous symptoms that may seem unrelated. These signs and symptoms may include mouth sores, eye inflammation, skin rashes and lesions, joint swelling, enlarged veins and arteries, inflammation in the brain and genital sores. The symptoms vary from person to person and may disappear and recur. The cause of Behçet’s disease is unknown. It may be an autoimmune disorder, which means the body’s immune system may be mistakenly attacking its own healthy cells.

Risk factors include age, location, sex, and genes. Individuals in their 20’s and 30’s are most likely to develop Behçet’s disease. The disease occurs worldwide, but is more common in the Middle East and Far East. The condition occurs in both men and women, but is usually more severe in men. It is believed that certain genes are associated with a higher risk of developing Behçet’s.

There is no treatment to cure Behçet’s disease. Doctors usually treat signs and symptoms to reduce the risk of complications, such as blindness. There is no definitive diagnostic test for Behçet’s disease; therefore, your doctor may conduct a physical exam and blood tests to rule out other conditions. Talk with your doctor about the most current treatment options if you or a family member has been diagnosed with Behçet’s disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's disease" for support, advocacy or research.

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American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

Last Updated: 11 Feb 2013

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Autoinflammatory Alliance

The Autoinflammatory Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases. We started in 2006 under the name, The NOMID Alliance with the same basic goal: to help patients with CAPS and other autoinflammatory diseases. We have a IRS approval as tax-exempt under both names.

Last Updated: 24 Jul 2015

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

Last Updated: 5 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's disease" for support, advocacy or research.

Logo
American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

https://www.behcets.com

Last Updated: 11 Feb 2013

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Autoinflammatory Alliance

The Autoinflammatory Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases. We started in 2006 under the name, The NOMID Alliance with the same basic goal: to help patients with CAPS and other autoinflammatory diseases. We have a IRS approval as tax-exempt under both names.

http://www.autoinflammatory.org

Last Updated: 24 Jul 2015

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

http://www.behcet.de

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

http://www.stopcaidnow.org

Last Updated: 5 Mar 2013

View Details

 

General Support Organizations

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General Resources

Healthier Ever After (injection tips book & program)

This child-friendly book is for patients and their families to learn how to manage their injectable medications, and has a program to help children to discuss and make a plan of care, and goals with rewards to chart on a reusable white board page.

Updated 6 May 2015

Open Doc
 
 
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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Behcet's disease" returned 795 free, full-text research articles on human participants. First 3 results:

Associations of HLA-B alleles with Behçet's disease in Ireland.
 

Author(s): Fahd Adeeb, Adaeze Ugwoke, Austin G Stack, Alexander D Fraser

Journal: Clin. Exp. Rheumatol.. ;35 Suppl 104(2):22-23.

 

Last Updated: 9 Jun 2017

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Serum PLR and LMR in Behçet's disease: Can they show the disease activity?
 

Author(s): Ying Jiang, Mingcui Zang, Shanshan Li

Journal: Medicine (Baltimore). 2017 May;96(21):e6981.

 

The aim of this study is to determine platelet to lymphocyte ratio (PLR) and lymphocytes to monocytes ratio (LMR) levels in Behçet's disease (BD) and to investigate their relationships with disease activity.Hematological and inflammatory parameters including high-sensitivity C-reactive ...

Last Updated: 24 May 2017

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[Cardiac pseudotumor revealing Behçet's disease].
 

Author(s): Fouad Nya, Abdessamad Abdou, Mehdi Bamous, Younes Moutakiallah, Noureddine Atmani, Aniss Seghrouchni, Mahdi Ait Houssa, Abdellatif Boulahya

Journal:

 

Intracardiac thrombosis is a rare complication of Behçet's disease (BD), which may manifest as intracardiac tumor. In half of cases, its detection precedes the diagnosis of MB. High mortality rates may be related to post-surgical complications and/or pulmonary arteries involvement. ...

Last Updated: 23 May 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Behcet's disease" returned 84 free, full-text review articles on human participants. First 3 results:

Frosted branch angiitis and cerebral venous sinus thrombosis as an initial onset of neuro-Behçet's disease: a case report and review of the literature.
 

Author(s): Bruno Fortaleza de Aquino Ferreira, Ever Ernesto Caso Rodriguez, Leandro Lara do Prado, Celio Roberto Gonçalves, Carlos Eduardo Hirata, Joyce Hisae Yamamoto

Journal:

 

Frosted branch angiitis is a rare, severe condition. It can be either a primary or a secondary condition and is characterized by rapid deterioration of vision and fulminant retinal vasculitis that manifests as diffuse sheathing of retinal vessels, macular edema, papillitis, vitritis ...

Last Updated: 15 Apr 2017

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Update on the Medical Management of Gastrointestinal Behçet's Disease.
 

Author(s): Giuseppe Lopalco, Donato Rigante, Vincenzo Venerito, Claudia Fabiani, Rossella Franceschini, Michele Barone, Giovanni Lapadula, Mauro Galeazzi, Bruno Frediani, Florenzo Iannone, Luca Cantarini

Journal: Mediators Inflamm.. 2017 ;2017():1460491.

 

Behçet's disease (BD) is a multisystemic disorder of unknown etiology mainly defined by recurrent oral aphthosis, genital ulcers, and chronic relapsing bilateral uveitis, all of which represent the "stigmata" of disease. However, many other organs including the vascular, neurological, ...

Last Updated: 17 Feb 2017

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[Panuveitis with oral and genital ulcer misdiagnosed as Behcet's disease: two cases report and literature review].
 

Author(s): Y Wang, L Yang, Z L Zhang

Journal: Beijing Da Xue Xue Bao. 2016 10;48(5):910-914.

 

Here we reported two patients who presented with panuveitis and were transferred from ophthalmologists to rheumatologists, for both the patients had oral and genital ulcers. They were misdiagnosed with Behcet's disease at first glance. Two young males presented with acute uveitis ...

Last Updated: 18 Oct 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Jul 2016

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Last Updated: 21 Mar 2017

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