Behcet's disease

Common Name(s)

Behcet's disease, Behcet disease

Behçet’s disease is a rare condition that causes inflammation in blood vessels throughout the body. Inflammation is characterized by redness, swelling and pain and is part of our normal immune response when injured or fighting infection. However, sometimes inflammation may be long term and cause problems. The inflammation caused by Behçet’s disease may lead to numerous symptoms that may seem unrelated. These signs and symptoms may include mouth sores, eye inflammation, skin rashes and lesions, joint swelling, enlarged veins and arteries, inflammation in the brain and genital sores. The symptoms vary from person to person and may disappear and recur. The cause of Behçet’s disease is unknown. It may be an autoimmune disorder, which means the body’s immune system may be mistakenly attacking its own healthy cells.

Risk factors include age, location, sex, and genes. Individuals in their 20’s and 30’s are most likely to develop Behçet’s disease. The disease occurs worldwide, but is more common in the Middle East and Far East. The condition occurs in both men and women, but is usually more severe in men. It is believed that certain genes are associated with a higher risk of developing Behçet’s.

There is no treatment to cure Behçet’s disease. Doctors usually treat signs and symptoms to reduce the risk of complications, such as blindness. There is no definitive diagnostic test for Behçet’s disease; therefore, your doctor may conduct a physical exam and blood tests to rule out other conditions. Talk with your doctor about the most current treatment options if you or a family member has been diagnosed with Behçet’s disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's disease" for support, advocacy or research.

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American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

Last Updated: 11 Feb 2013

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Autoinflammatory Alliance

The Autoinflammatory Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases. We started in 2006 under the name, The NOMID Alliance with the same basic goal: to help patients with CAPS and other autoinflammatory diseases. We have a IRS approval as tax-exempt under both names.

Last Updated: 24 Jul 2015

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

Last Updated: 5 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's disease" for support, advocacy or research.

Logo
American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

https://www.behcets.com

Last Updated: 11 Feb 2013

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Autoinflammatory Alliance

The Autoinflammatory Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases. We started in 2006 under the name, The NOMID Alliance with the same basic goal: to help patients with CAPS and other autoinflammatory diseases. We have a IRS approval as tax-exempt under both names.

http://www.autoinflammatory.org

Last Updated: 24 Jul 2015

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

http://www.behcet.de

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

http://www.stopcaidnow.org

Last Updated: 5 Mar 2013

View Details

 

General Support Organizations

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General Resources

Healthier Ever After (injection tips book & program)

This child-friendly book is for patients and their families to learn how to manage their injectable medications, and has a program to help children to discuss and make a plan of care, and goals with rewards to chart on a reusable white board page.

Updated 6 May 2015

Open Doc
 
 
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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Behcet's disease" returned 756 free, full-text research articles on human participants. First 3 results:

Thrombosis with Behçet's disease should be evaluated different conditions.
 

Author(s): Ilknur Balta, Sevket Balta, Mustafa Demir, Cengiz Ozturk, Sait Demirkol

Journal:

 

Last Updated: 19 Jun 2015

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Clinical Experience of Interferon Alfa-2a Treatment for Refractory Uveitis in Behçet's Disease.
 

Author(s): Ji-Youn Park, Yoo-Ri Chung, Kihwang Lee, Ji Hun Song, Eun-So Lee

Journal: Yonsei Med. J.. 2015 Jul;56(4):1158-62.

 

Behçet's disease (BD) involves multisystem vasculitis of unknown origin. Ocular manifestations of BD mostly include bilateral panuveitis and retinal vasculitis, which are very challenging to treat. Interferon alfa-2a (IFN) has been recently introduced for treating refractory Behçet ...

Last Updated: 13 Jun 2015

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Carpal Tunnel Syndrome in Behçet's Disease.
 

Author(s): Jungsoo Lee, Suhyun Cho, Do Young Kim, Zhenlong Zheng, Hoon Park, Dongsik Bang

Journal: Yonsei Med. J.. 2015 Jul;56(4):1015-20.

 

Behçet's disease (BD) is a chronic inflammatory disease characterized by orogenital ulcers, skin and ocular lesions, in addition to articular, vascular, and neurologic symptoms. Carpal tunnel syndrome (CTS), can also occur in BD patients secondary to inflammation in the connective ...

Last Updated: 13 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Behcet's disease" returned 72 free, full-text review articles on human participants. First 3 results:

Successful Treatment with Infliximab for Refractory Uveitis in a Hemodialysis Patient with Behçet's Disease and a Review of the Literature for Infliximab Use in Patients on Hemodialysis.
 

Author(s): Izumi Kurata, Hiroto Tsuboi, Hidenori Takahashi, Saori Abe, Hiroshi Ebe, Shinya Hagiwara, Naoto Umeda, Yuya Kondo, Hiroshi Ogishima, Takeshi Suzuki, Isao Matsumoto, Sujin Hoshi, Tetsuro Oshika, Takayuki Sumida

Journal: Intern. Med.. 2015 ;54(12):1553-7.

 

A 36-year-old man with a 16-year history of refractory Behçet's disease (BD)-associated uveitis and chronic renal failure requiring hemodialysis suffered from frequent ocular attacks despite treatment with systemic corticosteroids and cyclosporine A. Following infliximab administration, ...

Last Updated: 15 Jun 2015

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Gastrointestinal Behçet's disease: a review.
 

Author(s): Wasseem Skef, Matthew J Hamilton, Thurayya Arayssi

Journal: World J. Gastroenterol.. 2015 Apr;21(13):3801-12.

 

Behçet's disease (BD) is an idiopathic, chronic, relapsing, multi-systemic vasculitis characterized by recurrent oral and genital aphthous ulcers, ocular disease and skin lesions. Prevalence of BD is highest in countries along the ancient silk road from the Mediterranean basin to ...

Last Updated: 8 Apr 2015

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[Case of Behcet's disease diagnosed by bilateral epididymitis].
 

Author(s): Sayaka Horii, Shingo Takada, Takanori Kinjo, Daichi Nonomura, Yoshiyuki Yamamoto, Suguru Yoneda, Hironori Nomura, Norihide Tei, Kiyomi Matsumiya, Yoshimi Shiroyama

Journal: Hinyokika Kiyo. 2014 Nov;60(11):593-6.

 

A 24-year-old man visited our emergency room with testicular pain and left shoulder pain, and was admitted to our hospital for diagnosis of bilateral epididymitis. Antibiotics and anti-inflammatory medication were started, but the symptoms did not improve. During hospitalization, ...

Last Updated: 16 Dec 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Immunogenetic Mechanisms in Behcet's Disease
 

Status: Recruiting

Condition Summary: Behcet's Disease; Uveitis

 

Last Updated: 31 Dec 2015

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Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation)
 

Status: Recruiting

Condition Summary: Behcet's Disease

 

Last Updated: 27 Jan 2016

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