Behcet's Disease

Common Name(s)

Behcet's Disease, Behcet Disease

Behcet's disease is a chronic multisystem inflammatory disorder characterized by ulcers affecting the mouth and genitals, various skin lesions, and abnormalities affecting the eyes.  Although it can happen at any age, symptoms generally begin when individuals are in their 20s or 30s. The disease is common in Japan, Turkey and Israel, and less common in the United States. The exact cause of Behcet's disease is unknown.   Treatment is symptomatic and supportive.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's Disease" for support, advocacy or research.

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American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

Last Updated: 11 Feb 2013

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

Last Updated: 5 Mar 2013

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The NOMID Alliance

The NOMID Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases.

Last Updated: 16 Aug 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's Disease" for support, advocacy or research.

Logo
American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

https://www.behcets.com

Last Updated: 11 Feb 2013

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

http://www.behcet.de

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

http://www.stopcaidnow.org

Last Updated: 5 Mar 2013

View Details
The NOMID Alliance

The NOMID Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases.

http://www.nomidalliance.org

Last Updated: 16 Aug 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Behcet's Disease" returned 691 free, full-text research articles on human participants. First 3 results:

Amyloidosis in Behcet's disease.
 

Author(s): I Ben Ghorbel, N Bel Feki, T Ben Salem, M Lamloum, M H Houman

Journal: Saudi J Kidney Dis Transpl. 2015 Jan;26(1):132-4.

 

Behcet's disease (BD) is a multisystem vasculitis with protean manifestations. It is characterized by a heightened state of inflammation, although the factors that initiate and sustain this inflammation are not clear. We report some cases of BD-associated amyloidosis and have similar ...

Last Updated: 12 Jan 2015

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HLA-B51 subtypes in Turkish patients with Behçet's disease and their correlation with clinical manifestations.
 

Author(s): D D Demirseren, G G Ceylan, G Akoglu, S Emre, S Erten, A Arman, A Metin

Journal:

 

Behçet's disease (BD) is a multisystemic inflammatory disease believed to be triggered by microbial or environmental factors on a genetic platform. Clinically, it may have an impact on many body systems, including the mucocutaneous, ocular, articular, vascular, and neurological systems. ...

Last Updated: 26 Jul 2014

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Decreased expression of the aryl hydrocarbon receptor in ocular Behcet's disease.
 

Author(s): Chaokui Wang, Zi Ye, Aize Kijlstra, Yan Zhou, Peizeng Yang

Journal: Mediators Inflamm.. 2014 ;2014():195094.

 

Recent studies show that the aryl hydrocarbon receptor (AhR) is involved in immune responses. AhR is activated following interaction with its ligands, such as 6-formylindolo[3,2-b]carbazole (FICZ) and 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE). In this ...

Last Updated: 21 Jul 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Behcet's Disease" returned 70 free, full-text review articles on human participants. First 3 results:

Immunopathogenesis of ocular Behçet's disease.
 

Author(s): Un Chul Park, Tae Wan Kim, Hyeong Gon Yu

Journal: J Immunol Res. 2014 ;2014():653539.

 

Behçet's disease (BD) is a chronic recurrent systemic inflammatory disorder of unknown etiology characterized by oral and genital ulcerations, skin lesions, and uveitis. The ocular involvement of BD, or Behçet's uveitis (BU), is characterized by panuveitis or posterior uveitis with ...

Last Updated: 25 Jul 2014

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Biological treatments in Behçet's disease: beyond anti-TNF therapy.
 

Author(s): Francesco Caso, Luisa Costa, Donato Rigante, Orso Maria Lucherini, Paolo Caso, Vittoria Bascherini, Bruno Frediani, Rolando Cimaz, Edoardo Marrani, Laura Nieves-Martín, Mariangela Atteno, Carmela G L Raffaele, Giusyda Tarantino, Mauro Galeazzi, Leonardo Punzi, Luca Cantarini

Journal: Mediators Inflamm.. 2014 ;2014():107421.

 

Behçet's disease (BD) is universally recognized as a multisystemic inflammatory disease of unknown etiology with chronic course and unpredictable exacerbations: its clinical spectrum varies from pure vasculitic manifestations with thrombotic complications to protean inflammatory ...

Last Updated: 25 Jul 2014

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Behçet's disease-like symptoms associated with myelodysplastic syndrome with trisomy 8: a case report and review of the literature.
 

Author(s): Hanako Koguchi-Yoshioka, Daisuke Inokuma, Masatoshi Kanda, Makoto Kondo, Kazuhiro Kikuchi, Satoko Shimizu

Journal: Acta Derm. Venereol.. 2014 May;94(3):355-6.

 

Last Updated: 7 May 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Immunogenetic Mechanisms in Behcet's Disease
 

Status: Recruiting

Condition Summary: Behcet's Disease; Uveitis

 

Last Updated: 21 Jan 2015

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Efficacy and Safety Study of Gevokizumab to Treat Behcet's Disease Uveitis
 

Status: Recruiting

Condition Summary: Behcet's Disease Uveitis

 

Last Updated: 6 Mar 2015

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Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation)
 

Status: Recruiting

Condition Summary: Behcet's Disease

 

Last Updated: 16 Feb 2015

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