Behcet's Disease

Common Name(s)

Behcet's Disease, Behcet Disease

Behcet's disease is a chronic multisystem inflammatory disorder characterized by ulcers affecting the mouth and genitals, various skin lesions, and abnormalities affecting the eyes.  Although it can happen at any age, symptoms generally begin when individuals are in their 20s or 30s. The disease is common in Japan, Turkey and Israel, and less common in the United States. The exact cause of Behcet's disease is unknown.   Treatment is symptomatic and supportive.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's Disease" for support, advocacy or research.

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American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

Last Updated: 11 Feb 2013

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

Last Updated: 5 Mar 2013

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The NOMID Alliance

The NOMID Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases.

Last Updated: 16 Aug 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's Disease" for support, advocacy or research.

Logo
American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

https://www.behcets.com

Last Updated: 11 Feb 2013

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

http://www.behcet.de

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

http://www.stopcaidnow.org

Last Updated: 5 Mar 2013

View Details
The NOMID Alliance

The NOMID Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases.

http://www.nomidalliance.org

Last Updated: 16 Aug 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Behcet's Disease" returned 673 free, full-text research articles on human participants. First 3 results:

Vein of trolard sign on noncontrast computed tomography in Behcet's disease.
 

Author(s): Tamra Ranasinghe, William D Freeman

Journal: Acta Med Acad. 2014 ;43(1):97-8.

 

Last Updated: 4 Jun 2014

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[An usual case of vasculo- and neuro-Behçet's disease with MEFV mutations].
 

Author(s): Kosuke Okabe, Yasumori Izumi, Taiichiro Miyashita, Kensuke Irino, Chieko Kawahara, Yuka Jiuchi, Fumiaki Nonaka, Katsumi Eguchi, Atsushi Kawakami, Kiyoshi Migita

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2014 ;37(1):61-7.

 

  A 35-year-old man had a 2-year history of uveitis and arterial wall thickening of an aortic branching artery detected by magnetic resonance imaging. He was admitted to our hospital because of mental exaltation. He had been treated with a moderate dose of prednisolone (30 mg/ml) ...

Last Updated: 6 Mar 2014

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Evidence-based practice in Behçet's disease: identifying areas of unmet need for 2014.
 

Author(s): Robert J Barry, Bharat Markandey, Rahul Malhotra, Henry Knott, Nikita Joji, Mohammed Mubin, Alastair K Denniston, Phillip I Murray

Journal:

 

Behçet's Disease (BD) is characterized by a relapsing-remitting course, with symptoms of varying severity across almost all organ systems. There is a diverse array of therapeutic options with no universally accepted treatment regime, and it is thus important that clinical practice ...

Last Updated: 3 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Behcet's Disease" returned 67 free, full-text review articles on human participants. First 3 results:

Off-label uses of anti-TNF therapy in three frequent disorders: Behçet's disease, sarcoidosis, and noninfectious uveitis.
 

Author(s): Daniel Sánchez-Cano, José Luis Callejas-Rubio, Ricardo Ruiz-Villaverde, Raquel Ríos-Fernández, Norberto Ortego-Centeno

Journal: Mediators Inflamm.. 2013 ;2013():286857.

 

Tumoral necrosis factor α plays a central role in both the inflammatory response and that of the immune system. Thus, its blockade with the so-called anti-TNF agents (infliximab, etanercept, adalimumab, certolizumab pegol, and golimumab) has turned into the most important tool in ...

Last Updated: 28 Aug 2013

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The 2nd edition of consensus statements for the diagnosis and management of intestinal Behçet's disease: indication of anti-TNFα monoclonal antibodies.
 

Author(s): Tadakazu Hisamatsu, Fumiaki Ueno, Takayuki Matsumoto, Kiyonori Kobayashi, Kazutaka Koganei, Reiko Kunisaki, Fumihito Hirai, Masakazu Nagahori, Mitsunobu Matsushita, Kenji Kobayashi, Mitsumasa Kishimoto, Mitsuhiro Takeno, Masanori Tanaka, Nagamu Inoue, Toshifumi Hibi

Journal: J. Gastroenterol.. 2014 Jan;49(1):156-62.

 

Clinical evidence regarding intestinal Behçet's disease (BD) management is lacking and intestinal lesions are a poor prognostic factor. In 2007, the Japan consensus statement for diagnosis and management of intestinal BD was developed. Recently, the efficacy of anti-tumor necrosis ...

Last Updated: 20 Jan 2014

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Outcome predictors for intestinal Behçet's disease.
 

Author(s): Jae Jun Park, Won Ho Kim, Jae Hee Cheon

Journal: Yonsei Med. J.. 2013 Sep;54(5):1084-90.

 

Behçet's disease (BD) is a multisystem inflammatory disorder that presents as recurrent oral and genital ulcers in conjunction with other dermatological and ocular manifestations. The prevalence of BD is higher in Middle and East Asia than in Western countries. Intestinal BD is a ...

Last Updated: 6 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Immunogenetic Mechanisms in Behcet's Disease
 

Status: Recruiting

Condition Summary: Behcet's Disease; Uveitis

 

Last Updated: 14 Mar 2014

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Efficacy and Safety Study of Gevokizumab to Treat Behcet's Disease Uveitis
 

Status: Not yet recruiting

Condition Summary: Behcet's Disease Uveitis

 

Last Updated: 2 Oct 2014

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Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation)
 

Status: Recruiting

Condition Summary: Behcet's Disease

 

Last Updated: 31 Jul 2014

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