Behcet's Disease

Common Name(s)

Behcet's Disease, Behcet Disease

Behcet's disease is a chronic multisystem inflammatory disorder characterized by ulcers affecting the mouth and genitals, various skin lesions, and abnormalities affecting the eyes.  Although it can happen at any age, symptoms generally begin when individuals are in their 20s or 30s. The disease is common in Japan, Turkey and Israel, and less common in the United States. The exact cause of Behcet's disease is unknown.   Treatment is symptomatic and supportive.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's Disease" for support, advocacy or research.

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American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

Last Updated: 11 Feb 2013

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

Last Updated: 5 Mar 2013

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The NOMID Alliance

The NOMID Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases.

Last Updated: 16 Aug 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Behcet's Disease" for support, advocacy or research.

Logo
American Behcet's Disease Association (ABDA)

The American Behçet's Disease Association's mission is to provide support and information to people with Behçet's Disease and their families and to educate the medical community about Behçet's Disease. Through education, support, research and fundraising, the American Behçet's Disease Association is working to find a cure and to promote awareness and understanding of Behçet's Disease

https://www.behcets.com

Last Updated: 11 Feb 2013

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Deutsches Register Morbus Adamantiades-Behçet eV

The purpose of the association is the promotion of science and research in the field of Adamantiades-Behçet disease. This aim will be achieved by raising funds for the promotion of research projects in the field of Adamantiades-Behçet disease by other entities. Purpose of the association is the formation of doctors, patients and laypersons. Purpose of the association is also raising funds for the promotion of public health in the field of Adamantiades-Behçet disease by other entities.

http://www.behcet.de

Last Updated: 1 Apr 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

http://www.stopcaidnow.org

Last Updated: 5 Mar 2013

View Details
The NOMID Alliance

The NOMID Alliance is a 501 (c)(3) non-profit public charity dedicated to promoting awareness, proper diagnosis and treatment, and improved care for people with autoinflammatory diseases.

http://www.nomidalliance.org

Last Updated: 16 Aug 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Behcet's Disease" returned 664 free, full-text research articles on human participants. First 3 results:

Small bowel inflammatory involvement in Behçet's disease associated spondyloarthritis is different from other spondyloarthritides. A prospective cohort study.
 

Author(s): Mihai Rimbas, Adriana Nicolau, Simona Caraiola, Camelia G Badea, Mihail R Voiosu, Cristian R Baicus

Journal: J Gastrointestin Liver Dis. 2013 Dec;22(4):405-11.

 

Behçet's disease presents some similar clinical features with seronegative spondyloarthritides (SpA), raising the question whether a subgroup of patients with Behçet's disease belong in fact to the latter. As the already known inflammatory involvement at the level of the small bowel ...

Last Updated: 26 Dec 2013

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Combination therapy of infliximab and thalidomide for refractory entero-Behcet's disease: a case report.
 

Author(s): Yue Li, Zelong Han, Xianfei Wang, Zhihui Mo, Wei Zhang, Aimin Li, Side Liu

Journal:

 

Behcet's disease (BD) is a systemic inflammatory disease with the histopathological features of leukocytoclastic vasculitis that affects nearly all organs and systems. When it involves the intestine, it is called entero-Behcet's disease (entero-BD).

Last Updated: 17 Dec 2013

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HLA and non-HLA genes in Behçet's disease: a multicentric study in the Spanish population.
 

Author(s): Marco Montes-Cano, Marta Conde-Jaldón, José García-Lozano, Lourdes Ortiz-Fernández, Norberto Ortego-Centeno, María Castillo-Palma, Gerard Espinosa, Genaro Graña-Gil, Miguel González-Gay, Ana Barnosi-Marín, Roser Solans, Patricia Fanlo, Teresa Camps, Santos Castañeda, Juan Sánchez-Bursón, Antonio Núñez-Roldán, Javier Martín, María González-Escribano

Journal:

 

According to genome wide association (GWA) studies as well as candidate gene approaches, Behçet's disease (BD) is associated with human leukocyte antigen (HLA)-A and HLA-B gene regions. The HLA-B51 has been consistently associated with the disease, but the role of other HLA class ...

Last Updated: 29 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Behcet's Disease" returned 66 free, full-text review articles on human participants. First 3 results:

Off-label uses of anti-TNF therapy in three frequent disorders: Behçet's disease, sarcoidosis, and noninfectious uveitis.
 

Author(s): Daniel Sánchez-Cano, José Luis Callejas-Rubio, Ricardo Ruiz-Villaverde, Raquel Ríos-Fernández, Norberto Ortego-Centeno

Journal: Mediators Inflamm.. 2013 ;2013():286857.

 

Tumoral necrosis factor α plays a central role in both the inflammatory response and that of the immune system. Thus, its blockade with the so-called anti-TNF agents (infliximab, etanercept, adalimumab, certolizumab pegol, and golimumab) has turned into the most important tool in ...

Last Updated: 28 Aug 2013

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Outcome predictors for intestinal Behçet's disease.
 

Author(s): Jae Jun Park, Won Ho Kim, Jae Hee Cheon

Journal: Yonsei Med. J.. 2013 Sep;54(5):1084-90.

 

Behçet's disease (BD) is a multisystem inflammatory disorder that presents as recurrent oral and genital ulcers in conjunction with other dermatological and ocular manifestations. The prevalence of BD is higher in Middle and East Asia than in Western countries. Intestinal BD is a ...

Last Updated: 6 Aug 2013

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[Behcet's disease complicated by malignant lymphoma: a case report and literature review].
 

Author(s): Qin Huang, Weinan Lai, Min Yang

Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2013 Jun;33(6):934-6.

 

Malignant lymphoma complicated by Behcet's disease (BD) is a rare clinical entity. We report a case of BD complicated by malignant lymphoma in a 26-year-old male patient. The patient was diagnosed to have terminal ileum extranodal NK/T-cell lymphoma (nasal type) during treatment for ...

Last Updated: 27 Jun 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Immunogenetic Mechanisms in Behcet's Disease
 

Status: Recruiting

Condition Summary: Behcet's Disease; Uveitis

 

Last Updated: 14 Mar 2014

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Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation)
 

Status: Recruiting

Condition Summary: Behcet's Disease

 

Last Updated: 31 Jul 2014

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Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet`s Disease (INCYTOB)
 

Status: Recruiting

Condition Summary: Behcet's Disease; Panuveitis; Posterior Uveitis; Retinal Vasculitis

 

Last Updated: 26 Jul 2010

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