Autism 17

Common Name(s)

Autism 17

Autism, the prototypic pervasive developmental disorder (PDD), is usually apparent by 3 years of age. It is characterized by a triad of limited or absent verbal communication, a lack of reciprocal social interaction or responsiveness, and restricted, stereotypic, and ritualized patterns of interests and behavior ({1:Bailey et al., 1996}; {4:Risch et al., 1999}). 'Autism spectrum disorder,' sometimes referred to as ASD, is a broader phenotype encompassing the less severe disorders Asperger syndrome (see ASPG1; {608638}) and pervasive developmental disorder, not otherwise specified (PDD-NOS). 'Broad autism phenotype' includes individuals with some symptoms of autism, but who do not meet the full criteria for autism or other disorders. Mental retardation coexists in approximately two-thirds of individuals with ASD, except for Asperger syndrome, in which mental retardation is conspicuously absent ({3:Jones et al., 2008}). Genetic studies in autism often include family members with these less stringent diagnoses ({5:Schellenberg et al., 2006}). For a discussion of genetic heterogeneity of autism, see {209850}.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Autism 17" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Autism 17" returned 4 free, full-text research articles on human participants. First 3 results:

Decreased cellular IL-23 but not IL-17 production in children with autism spectrum disorders.
 

Author(s): Charity Onore, Amanda Enstrom, Paula Krakowiak, Irva Hertz-Picciotto, Robin Hansen, Judy Van de Water, Paul Ashwood

Journal: J. Neuroimmunol.. 2009 Nov;216(1-2):126-9.

 

A potential role for T(H)17 cells has been suggested in a number of conditions including neurodevelopmental disorders such as autism spectrum disorders (ASD). In the current study, we investigated cellular release of IL-17 and IL-23 following an in-vitro immunological challenge of ...

Last Updated: 17 Nov 2009

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High density SNP association study of a major autism linkage region on chromosome 17.
 

Author(s): Jennifer L Stone, Barry Merriman, Rita M Cantor, Daniel H Geschwind, Stanley F Nelson

Journal: Hum. Mol. Genet.. 2007 Mar;16(6):704-15.

 

A region on chromosome 17 has recently been highlighted as linked to autism (MIM[209850]) in multiple studies and evidence has accumulated suggesting that male-only families (those families that have produced only affected males) provide the major contribution to linkage at this locus. ...

Last Updated: 6 Apr 2007

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Characterization of Potocki-Lupski syndrome (dup(17)(p11.2p11.2)) and delineation of a dosage-sensitive critical interval that can convey an autism phenotype.
 

Author(s): Lorraine Potocki, Weimin Bi, Diane Treadwell-Deering, Claudia M B Carvalho, Anna Eifert, Ellen M Friedman, Daniel Glaze, Kevin Krull, Jennifer A Lee, Richard Alan Lewis, Roberto Mendoza-Londono, Patricia Robbins-Furman, Chad Shaw, Xin Shi, George Weissenberger, Marjorie Withers, Svetlana A Yatsenko, Elaine H Zackai, Pawel Stankiewicz, James R Lupski

Journal: Am. J. Hum. Genet.. 2007 Apr;80(4):633-49.

 

The duplication 17p11.2 syndrome, associated with dup(17)(p11.2p11.2), is a recently recognized syndrome of multiple congenital anomalies and mental retardation and is the first predicted reciprocal microduplication syndrome described--the homologous recombination reciprocal of the ...

Last Updated: 14 Mar 2007

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Autism 17" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Short Treatment Study of Aripiprazole in Pediatric Patients With Autistic Disorder
 

Status: Recruiting

Condition Summary: Autistic Disorder

 

Last Updated: 19 Dec 2013

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Last Updated: 19 Dec 2013

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TSO in Pediatric Autistic Spectrum Disorders
 

Status: Recruiting

Condition Summary: Autistic Spectrum Disorders

 

Last Updated: 16 Apr 2014

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