Anxiety

Common Name(s)

Anxiety

Human personality is shaped by genetic and environmental factors, and evidence suggests that the genetic component is highly complex, polygenic, and epistatic. Genetic factors are thought to contribute to 40 to 60% of trait variance. Molecular genetics has tried to identify specific genes for quantitative traits, called quantitative trait loci (QTLs). The QTL concept suggests that complex personality traits or dimensions are not attributable to single genes, but to multiple interacting genes ({15:Reif and Lesch, 2003)}. {2:Fullerton et al. (2003)} stated that psychologists were in agreement that the wide variation in human personalities can be explained by a small number of personality factors, including neuroticism (a measure of emotional stability), which manifests at one extreme as anxiety, depression, moodiness, low self-esteem, and diffidence. They cited a number of studies that had described a relationship between high scores on measures of neuroticism and major depressive disorder. They also noted that theoretical studies had suggested that large samples of randomly ascertained sibs could be used to ascertain phenotypically extreme individuals and thereby increase power to detect genetic linkage in complex traits. See also panic disorder (PAND1; {167870}), which is a subtype of anxiety disorder.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

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Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

Last Updated: 24 Jun 2015

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

http://www.adaa.org

Last Updated: 24 Jun 2015

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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General Resources

The 504 Plan for Selective Mutism: A Social Anxiety Disorder

Preschool - grade 12 school based accommodation plan

Updated 26 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anxiety" returned 3726 free, full-text research articles on human participants. First 3 results:

[Individual differences in sleep macrostructure: effects of anxiety, depression, aging and gender].
 

Author(s): András Horváth, Anna Szücs, Xavier Montana, Jean-Pol Lanquart, Philippe Hubain, Mathilde Flamand, Paul Linkowski, Gwenolé Loas

Journal: Neuropsychopharmacol Hung. 2015 Sep;17(3):146-56.

 

Anxiety is one of the most common psychiatric symptoms frequently associated with sleep disorders. Despite the intensive research, the role of sleep in the patomechanism of anxiety has remained unclear. The aim of the study was to investigate the anxiety-related changes in the sleep ...

Last Updated: 21 Oct 2015

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Reliability and validity of the Hospital Anxiety and Depression Scale in an emergency department in Saudi Arabia: a cross-sectional observational study.
 

Author(s): Zohair A Al Aseri, M Owais Suriya, Hosam A Hassan, Mujtaba Hasan, Shaffi Ahmed Sheikh, Adel Al Tamimi, Mashhoor Alshathri, Najeeb Khalid

Journal:

 

Depression and anxiety are prevalent psychiatric comorbidities that are known to have a negative impact on a patient's general prognosis. But screening for these potential comorbidities in a hospital's accident and emergency department has seldom been undertaken, particularly in Saudi ...

Last Updated: 13 Oct 2015

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[Anxiety status and influential factors in patients with infertility].
 

Author(s): Fang Wu, Yang Liu, Xiaogang Li

Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2015 Sep;40(9):1023-8.

 

To investigate the anxiety status of infertile patients and the influential factors.


Last Updated: 26 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anxiety" returned 408 free, full-text review articles on human participants. First 3 results:

The Modulatory Role of Dopamine in Anxiety-like Behavior.
 

Author(s): Mohammad-Reza Zarrindast, Fatemeh Khakpai

Journal: Arch Iran Med. 2015 Sep;18(9):591-603.

 

Anxiety is an unpleasant physiological state in which an overreaction to a situation occurs. It has been suggested that different brain regions are involved in the modulation and expression of anxiety, including the amygdala, hippocampus, and frontal cortex. Dysfunction of neurotransmitters ...

Last Updated: 31 Aug 2015

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Changes Needed in the Classification of Anxiety Disorders in Childhood: Options for ICD-11.
 

Author(s): Miodrag Stanković, Grozdanko Grbeša, Jelena Kostić, Sandra Stanković, Jelena Stevanović

Journal: Srp Arh Celok Lek. ;143(5-6):369-72.

 

Considering the intensive preparation of the 11th revision of the International Classification of Diseases (ICD-11), we discussed the justification of the existing classification of emotional disorders with onset specific to childhood. This paper presents the citations from the ICD-10 ...

Last Updated: 11 Aug 2015

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[An update on the conceptual and classification issues of anxiety, its neuroanatomy and problems of anxiolytic drug discovery].
 

Author(s): Gábor Faludi, Xénia Gonda, Péter Döme

Journal: Neuropsychopharmacol Hung. 2015 Jun;17(2):69-80.

 

Anxiety disorders are highly prevalent psychiatric diseases. In this short review we provide an overview of concepts of fear, anxiety and anxiety disorders. In addition, based on the recent literature, neuroanatomical structures involved in anxiety and functional/structural changes ...

Last Updated: 21 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 14 Sep 2012

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Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
 

Status: Recruiting

Condition Summary: Autism Spectrum Disorders; Autism; Asperger's Syndrome; Pervasive Developmental Disability - Not Otherwise Specified; Obsessive-compulsive Disorder; Social Phobia; Generalized Anxiety Disorder; Specific Phobia; Separation Anxiety Disorder

 

Last Updated: 1 Dec 2015

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Explanatory Clinical Trial of a Novel Parent Intervention for Childhood Anxiety (SPACE)
 

Status: Recruiting

Condition Summary: Anxiety Disorders; Anxiety, Separation; Phobic Disorders

 

Last Updated: 14 Jul 2015

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