Anxiety

Common Name(s)

Anxiety

Human personality is shaped by genetic and environmental factors, and evidence suggests that the genetic component is highly complex, polygenic, and epistatic. Genetic factors are thought to contribute to 40 to 60% of trait variance. Molecular genetics has tried to identify specific genes for quantitative traits, called quantitative trait loci (QTLs). The QTL concept suggests that complex personality traits or dimensions are not attributable to single genes, but to multiple interacting genes ({15:Reif and Lesch, 2003)}. {2:Fullerton et al. (2003)} stated that psychologists were in agreement that the wide variation in human personalities can be explained by a small number of personality factors, including neuroticism (a measure of emotional stability), which manifests at one extreme as anxiety, depression, moodiness, low self-esteem, and diffidence. They cited a number of studies that had described a relationship between high scores on measures of neuroticism and major depressive disorder. They also noted that theoretical studies had suggested that large samples of randomly ascertained sibs could be used to ascertain phenotypically extreme individuals and thereby increase power to detect genetic linkage in complex traits. See also panic disorder (PAND1; {167870}), which is a subtype of anxiety disorder.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

Last Updated: 15 Feb 2013

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

http://www.adaa.org

Last Updated: 15 Feb 2013

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

The 504 Plan for Selective Mutism: A Social Anxiety Disorder

Preschool - grade 12 school based accommodation plan

Updated 26 Mar 2013

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anxiety" returned 2795 free, full-text research articles on human participants. First 3 results:

Anxiety sensitivity in bereaved adults with and without complicated grief.
 

Author(s): Donald J Robinaugh, Richard J McNally, Nicole J LeBlanc, Kimberly Z Pentel, Noah R Schwarz, Riva M Shah, Mireya F Nadal-Vicens, Cynthia W Moore, Luana Marques, Eric Bui, Naomi M Simon

Journal: J. Nerv. Ment. Dis.. 2014 Aug;202(8):620-2.

 

Complicated grief (CG) is a bereavement-specific syndrome chiefly characterized by symptoms of persistent separation distress. Physiological reactivity to reminders of the loss and repeated acute pangs or waves of severe anxiety and psychological pain are prominent features of CG. ...

Last Updated: 31 Jul 2014

Go To URL
Altered activity and functional connectivity of superior temporal gyri in anxiety disorders: a functional magnetic resonance imaging study.
 

Author(s): Xiaohu Zhao, Qian Xi, Peijun Wang, Chunbo Li, Hongjian He

Journal: Korean J Radiol. ;15(4):523-9.

 

The prior functional MRI studies have demonstrated significantly abnormal activity in the bilateral superior temporal gyrus (STG) of anxiety patients. The purpose of the current investigation was to determine whether the abnormal activity in these regions was related to a loss of ...

Last Updated: 23 Jul 2014

Go To URL
Is anxiety best conceived as a unitary condition? The benefits of lumping compared with splitting . . .
 

Author(s): Margaret A Richter

Journal: Can J Psychiatry. 2014 Jun;59(6):291-3.

 

Last Updated: 10 Jul 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anxiety" returned 333 free, full-text review articles on human participants. First 3 results:

Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders.
 

Author(s): Martin A Katzman, Pierre Bleau, Pierre Blier, Pratap Chokka, Kevin Kjernisted, Michael Van Ameringen, , Martin M Antony, St├ęphane Bouchard, Alain Brunet, Martine Flament, Sophie Grigoriadis, Sandra Mendlowitz, Kieron O'Connor, Kiran Rabheru, Peggy M A Richter, Melisa Robichaud, John R Walker

Journal: BMC Psychiatry. 2014 ;14 Suppl 1():S1.

 

Anxiety and related disorders are among the most common mental disorders, with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are under-diagnosed and under-treated.

Last Updated: 1 Aug 2014

Go To URL
Protocol for a systematic review and meta-analysis of cognitive-behavioural therapy for social anxiety disorder in psychosis.
 

Author(s): Maria Michail, Max Birchwood, Lynda Tait

Journal:

 

Social anxiety is among the most prevalent and debilitating affective disturbances manifest in people with psychosis. It is usually accompanied by high levels of depression and leads to significant social disability, lower quality of life and poorer prognosis as it raises the possibility ...

Last Updated: 23 Jun 2014

Go To URL
Depression and anxiety predict health-related quality of life in chronic obstructive pulmonary disease: systematic review and meta-analysis.
 

Author(s): Amy Blakemore, Chris Dickens, Else Guthrie, Peter Bower, Evangelos Kontopantelis, Cara Afzal, Peter A Coventry

Journal:

 

The causal association between depression, anxiety, and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD) is unclear. We therefore conducted a systematic review of prospective cohort studies that measured depression, anxiety, and HRQoL in COPD.

Last Updated: 30 May 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Brief Behavioral Treatment for Anxiety in Young Children
 

Status: Recruiting

Condition Summary: Obsessive-compulsive Disorder; Social Phobia; Generalized Anxiety Disorder; Specific Phobia; Separation Anxiety Disorder; Selective Mutism; Anxiety Disorder, Not Otherwise Specified

 

Last Updated: 15 Sep 2014

Go to URL

Last Updated: 14 Sep 2012

Go to URL
Brain Markers of Anxiety Disorders and SSRI/CBT Treatment in Children and Adolescents
 

Status: Recruiting

Condition Summary: Social Phobia; Generalized Anxiety Disorder; Separation Anxiety Disorder

 

Last Updated: 23 Nov 2011

Go to URL