Anxiety

Common Name(s)

Anxiety

Human personality is shaped by genetic and environmental factors, and evidence suggests that the genetic component is highly complex, polygenic, and epistatic. Genetic factors are thought to contribute to 40 to 60% of trait variance. Molecular genetics has tried to identify specific genes for quantitative traits, called quantitative trait loci (QTLs). The QTL concept suggests that complex personality traits or dimensions are not attributable to single genes, but to multiple interacting genes ({15:Reif and Lesch, 2003}). {2:Fullerton et al. (2003)} stated that psychologists were in agreement that the wide variation in human personalities can be explained by a small number of personality factors, including neuroticism (a measure of emotional stability), which manifests at one extreme as anxiety, depression, moodiness, low self-esteem, and diffidence. They cited a number of studies that had described a relationship between high scores on measures of neuroticism and major depressive disorder. They also noted that theoretical studies had suggested that large samples of randomly ascertained sibs could be used to ascertain phenotypically extreme individuals and thereby increase power to detect genetic linkage in complex traits. See also panic disorder (PAND1; {167870}), which is a subtype of anxiety disorder.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

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Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

Last Updated: 24 Jun 2015

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

http://www.adaa.org

Last Updated: 24 Jun 2015

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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General Support Organizations

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General Resources

The 504 Plan for Selective Mutism: A Social Anxiety Disorder

Preschool - grade 12 school based accommodation plan

Updated 26 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anxiety" returned 4764 free, full-text research articles on human participants. First 3 results:

Clinical impact of depression and anxiety in patients with idiopathic pulmonary fibrosis.
 

Author(s): Ye Jin Lee, Sun Mi Choi, Yeon Joo Lee, Young-Jae Cho, Ho Il Yoon, Jae-Ho Lee, Choon-Taek Lee, Jong Sun Park

Journal:

 

Although depression and anxiety represent significant yet treatable comorbidities in patients with idiopathic pulmonary fibrosis (IPF), their impact on the clinical course and prognosis of IPF remain unclear.

Last Updated: 11 Sep 2017

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Comorbidity of post-traumatic stress disorder and anxiety in flood survivors: Prevalence and shared risk factors.
 

Author(s): Wenjie Dai, Atipatsa C Kaminga, Hongzhuan Tan, Jieru Wang, Zhiwei Lai, Xin Wu, Yuan Xiong, Jing Deng, Aizhong Liu

Journal: Medicine (Baltimore). 2017 Sep;96(36):e7994.

 

Post-traumatic stress disorder (PTSD) and anxiety are both prevalent in trauma-related populations. However, comorbidity of these 2 psychiatric disorders has not been investigated in flood survivors. This study aimed to estimate the extent to which PTSD and anxiety co-occur in flood ...

Last Updated: 8 Sep 2017

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Lef1-dependent hypothalamic neurogenesis inhibits anxiety.
 

Author(s): Yuanyuan Xie, Dan Kaufmann, Matthew J Moulton, Samin Panahi, John A Gaynes, Harrison N Watters, Dingxi Zhou, Hai-Hui Xue, Camille M Fung, Edward M Levine, Anthea Letsou, K C Brennan, Richard I Dorsky

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While innate behaviors are conserved throughout the animal kingdom, it is unknown whether common signaling pathways regulate the development of neuronal populations mediating these behaviors in diverse organisms. Here, we demonstrate that the Wnt/├č-catenin effector Lef1 is required ...

Last Updated: 24 Aug 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anxiety" returned 640 free, full-text review articles on human participants. First 3 results:

Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials.
 

Author(s): Neeltje M Batelaan, Renske C Bosman, Anna Muntingh, Willemijn D Scholten, Klaas M Huijbregts, Anton J L M van Balkom

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Objectives To examine the risk of relapse and time to relapse after discontinuation of antidepressants in patients with anxiety disorder who responded to antidepressants, and to explore whether relapse risk is related to type of anxiety disorder, type of antidepressant, mode of discontinuation, ...

Last Updated: 14 Sep 2017

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Prevalence of depression and anxiety in systemic lupus erythematosus: a systematic review and meta-analysis.
 

Author(s): Lijuan Zhang, Ting Fu, Rulan Yin, Qiuxiang Zhang, Biyu Shen

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Systemic lupus erythematosus (SLE) patients are at high risk for depression and anxiety. However, the estimated prevalence of these disorders varies substantially between studies. This systematic review aimed to establish pooled prevalence levels of depression and anxiety among adult SLE patients.

Last Updated: 15 Feb 2017

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Guidelines for dementia or Parkinson's disease with depression or anxiety: a systematic review.
 

Author(s): Zahra Goodarzi, Bria Mele, Selynne Guo, Heather Hanson, Nathalie Jette, Scott Patten, Tamara Pringsheim, Jayna Holroyd-Leduc

Journal:

 

Depression and anxiety remain under-diagnosed and under-treated in those with neurologic diseases such as dementia or Parkinson's Disease (PD). Our objectives were to first, to provide a synthesis of high quality guidelines available for the identification and management of depression ...

Last Updated: 26 Nov 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 29 Jun 2016

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Elective Coronary Angiography and Anxiety Study
 

Status: Recruiting

Condition Summary: Anxiety

 

Last Updated: 8 Aug 2016

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Last Updated: 8 Aug 2017

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