Anxiety

Common Name(s)

Anxiety

Human personality is shaped by genetic and environmental factors, and evidence suggests that the genetic component is highly complex, polygenic, and epistatic. Genetic factors are thought to contribute to 40 to 60% of trait variance. Molecular genetics has tried to identify specific genes for quantitative traits, called quantitative trait loci (QTLs). The QTL concept suggests that complex personality traits or dimensions are not attributable to single genes, but to multiple interacting genes ({15:Reif and Lesch, 2003)}. {2:Fullerton et al. (2003)} stated that psychologists were in agreement that the wide variation in human personalities can be explained by a small number of personality factors, including neuroticism (a measure of emotional stability), which manifests at one extreme as anxiety, depression, moodiness, low self-esteem, and diffidence. They cited a number of studies that had described a relationship between high scores on measures of neuroticism and major depressive disorder. They also noted that theoretical studies had suggested that large samples of randomly ascertained sibs could be used to ascertain phenotypically extreme individuals and thereby increase power to detect genetic linkage in complex traits. See also panic disorder (PAND1; {167870}), which is a subtype of anxiety disorder.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

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Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

Last Updated: 15 Feb 2013

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

http://www.adaa.org

Last Updated: 15 Feb 2013

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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General Resources

The 504 Plan for Selective Mutism: A Social Anxiety Disorder

Preschool - grade 12 school based accommodation plan

Updated 26 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anxiety" returned 3043 free, full-text research articles on human participants. First 3 results:

The lifetime prevalence of anxiety disorders among patients with irritable bowel syndrome.
 

Author(s): Magdalena Grzesiak, Jan A Beszłej, Agata Mulak, Marcin Szechiński, Monika Szewczuk-Bogusławska, Ewa Waszczuk, Monika Kantorska, Dorota Frydecka

Journal: Adv Clin Exp Med. ;23(6):987-92.

 

The prevalence of irritable bowel syndrome (IBS), the most common functional gastrointestinal disorder, ranges from 10% to 20% in the general population. It is estimated that from 40% to 90% of persons with a diagnosis of IBS suffer from mental disorders, mainly anxiety and depressive disorders.

Last Updated: 27 Jan 2015

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[Paroxysmal events after anxiety treatment with fluoxetine in a child with autism spectrum disorder].
 

Author(s): A Simons, J Steyaert

Journal: Tijdschr Psychiatr. 2014 ;56(12):821-4.

 

Anxiety is common in children and adolescents with autism spectrum disorders and can cause severe dysfunction and suffering. An 11-year-old boy with an autism spectrum disorder and suffering from anxiety and mood problems responded positively to treatment with fluoxetine. After four ...

Last Updated: 16 Dec 2014

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Cognitive enhancement or cognitive cost: trait-specific outcomes of brain stimulation in the case of mathematics anxiety.
 

Author(s): Amar Sarkar, Ann Dowker, Roi Cohen Kadosh

Journal: J. Neurosci.. 2014 Dec;34(50):16605-10.

 

The surge in noninvasive brain stimulation studies investigating cognitive enhancement has neglected the effect of interindividual differences, such as traits, on stimulation outcomes. Using the case of mathematics anxiety in a sample of healthy human participants in a placebo-controlled, ...

Last Updated: 16 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anxiety" returned 346 free, full-text review articles on human participants. First 3 results:

Overview of the prevalence, impact, and management of depression and anxiety in chronic obstructive pulmonary disease.
 

Author(s): Maria Panagioti, Charlotte Scott, Amy Blakemore, Peter A Coventry

Journal:

 

More than one third of individuals with chronic obstructive pulmonary disease (COPD) experience comorbid symptoms of depression and anxiety. This review aims to provide an overview of the burden of depression and anxiety in those with COPD and to outline the contemporary advances ...

Last Updated: 24 Nov 2014

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Assessment of patient-reported symptoms of anxiety.
 

Author(s): Matthias Rose, Janine Devine

Journal: Dialogues Clin Neurosci. 2014 Jun;16(2):197-211.

 

Patient self-reported symptoms are of crucial importance to identify anxiety disorders, as well as to monitor their treatment in clinical practice and research. Thus, for evidence-based medicine, a precise, reliable, and valid (ie, "objective") assessment of the patient's reported ...

Last Updated: 25 Aug 2014

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The diagnosis of and treatment recommendations for anxiety disorders.
 

Author(s): Borwin Bandelow, Thomas Lichte, Sebastian Rudolf, Jörg Wiltink, Manfred E Beutel

Journal: Dtsch Arztebl Int. 2014 Jul;111(27-28):473-80.

 

Anxiety disorders (panic disorder/agoraphobia, generalized anxiety disorder, social phobia, and specific phobias) are the most common mental illnesses. For example, the 12-month prevalence of panic disorder/agoraphobia is 6%.

Last Updated: 20 Aug 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Brief Behavioral Treatment for Anxiety in Young Children
 

Status: Recruiting

Condition Summary: Obsessive-compulsive Disorder; Social Phobia; Generalized Anxiety Disorder; Specific Phobia; Separation Anxiety Disorder; Selective Mutism; Anxiety Disorder, Not Otherwise Specified

 

Last Updated: 7 Apr 2015

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Last Updated: 14 Sep 2012

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Brain Markers of Anxiety Disorders and SSRI/CBT Treatment in Children and Adolescents
 

Status: Recruiting

Condition Summary: Social Phobia; Generalized Anxiety Disorder; Separation Anxiety Disorder

 

Last Updated: 23 Nov 2011

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