Anxiety

Common Name(s)

Anxiety

Human personality is shaped by genetic and environmental factors, and evidence suggests that the genetic component is highly complex, polygenic, and epistatic. Genetic factors are thought to contribute to 40 to 60% of trait variance. Molecular genetics has tried to identify specific genes for quantitative traits, called quantitative trait loci (QTLs). The QTL concept suggests that complex personality traits or dimensions are not attributable to single genes, but to multiple interacting genes ({15:Reif and Lesch, 2003)}. {2:Fullerton et al. (2003)} stated that psychologists were in agreement that the wide variation in human personalities can be explained by a small number of personality factors, including neuroticism (a measure of emotional stability), which manifests at one extreme as anxiety, depression, moodiness, low self-esteem, and diffidence. They cited a number of studies that had described a relationship between high scores on measures of neuroticism and major depressive disorder. They also noted that theoretical studies had suggested that large samples of randomly ascertained sibs could be used to ascertain phenotypically extreme individuals and thereby increase power to detect genetic linkage in complex traits. See also panic disorder (PAND1; {167870}), which is a subtype of anxiety disorder.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

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Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

Last Updated: 24 Jun 2015

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

http://www.adaa.org

Last Updated: 24 Jun 2015

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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General Resources

The 504 Plan for Selective Mutism: A Social Anxiety Disorder

Preschool - grade 12 school based accommodation plan

Updated 26 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anxiety" returned 4021 free, full-text research articles on human participants. First 3 results:

Changes in trait brainwave power and coherence, state and trait anxiety after three-month transcendental meditation (TM) practice.
 

Author(s): Helena Tomljenović, Dražen Begić, Zora Maštrović

Journal: Psychiatr Danub. 2016 Mar;28(1):63-72.

 

The amount of studies showing different benefits of practicing meditation is growing. EEG brainwave patterns objectively reflect both the cognitive processes and objects of meditation. This study aimed to examine the effects of transcendental meditation (TM) practice on baseline EEG ...

Last Updated: 4 Mar 2016

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[Association between anxiety-depression and 5-HTTLPR gene polymorphism in school-aged twins].
 

Author(s): Qiao Zhao, Yu-Ling Li, Enherbayaer, Yan Liu, Yi Ding

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2016 Jan;18(1):61-6.

 

To investigate the association between anxiety-depression and 5-HTTLPR gene polymorphism in school-aged twins.

Last Updated: 19 Jan 2016

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Anxiety, depression, perceived social support and quality of life in Malaysian breast cancer patients: a 1-year prospective study.
 

Author(s): Chong Guan Ng, Salina Mohamed, Mee Hoong See, Faizah Harun, Maznah Dahlui, Ahmad Hatim Sulaiman, Nor Zuraida Zainal, Nur Aishah Taib,

Journal:

 

Depression and anxiety are common psychiatric morbidity among breast cancer patient. There is a lack of study examining the correlation between depression, anxiety and quality of life (QoL) with perceived social support (PSS) among breast cancer patients. This study aims to study ...

Last Updated: 30 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anxiety" returned 430 free, full-text review articles on human participants. First 3 results:

Effectiveness of Mindfulness-based Therapy for Reducing Anxiety and Depression in Patients With Cancer: A Meta-analysis.
 

Author(s): Mei-Fen Zhang, Yong-Shan Wen, Wei-Yan Liu, Li-Fen Peng, Xiao-Dan Wu, Qian-Wen Liu

Journal: Medicine (Baltimore). 2015 Nov;94(45):e0897-0.

 

Anxiety and depression are common among patients with cancer, and are often treated with psychological interventions including mindfulness-based therapy.The aim of the study was to perform a meta-analysis of the effectiveness of mindfulness-based interventions for improving anxiety ...

Last Updated: 12 Nov 2015

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International Committee on Mental Health in Cystic Fibrosis: Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus statements for screening and treating depression and anxiety.
 

Author(s): Alexandra L Quittner, Janice Abbott, Anna M Georgiopoulos, Lutz Goldbeck, Beth Smith, Sarah E Hempstead, Bruce Marshall, Kathryn A Sabadosa, Stuart Elborn, ,

Journal: Thorax. 2016 Jan;71(1):26-34.

 

Studies measuring psychological distress in individuals with cystic fibrosis (CF) have found high rates of both depression and anxiety. Psychological symptoms in both individuals with CF and parent caregivers have been associated with decreased lung function, lower body mass index, ...

Last Updated: 18 Dec 2015

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The Modulatory Role of Dopamine in Anxiety-like Behavior.
 

Author(s): Mohammad-Reza Zarrindast, Fatemeh Khakpai

Journal: Arch Iran Med. 2015 Sep;18(9):591-603.

 

Anxiety is an unpleasant physiological state in which an overreaction to a situation occurs. It has been suggested that different brain regions are involved in the modulation and expression of anxiety, including the amygdala, hippocampus, and frontal cortex. Dysfunction of neurotransmitters ...

Last Updated: 31 Aug 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety
 

Status: Not yet recruiting

Condition Summary: Anxiety Disorders; Social Anxiety Disorder; Social Phobia; Generalized Anxiety Disorder; Separation Anxiety Disorder; Specific Phobia; Phobia; Agoraphobia; Panic Disorder; Panic Attack; Anxiety

 

Last Updated: 21 Jun 2016

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Last Updated: 14 Sep 2012

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Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
 

Status: Recruiting

Condition Summary: Autism Spectrum Disorders; Autism; Asperger's Syndrome; Pervasive Developmental Disability - Not Otherwise Specified; Obsessive-compulsive Disorder; Social Phobia; Generalized Anxiety Disorder; Specific Phobia; Separation Anxiety Disorder

 

Last Updated: 7 Mar 2016

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