Anxiety

Common Name(s)

Anxiety

Human personality is shaped by genetic and environmental factors, and evidence suggests that the genetic component is highly complex, polygenic, and epistatic. Genetic factors are thought to contribute to 40 to 60% of trait variance. Molecular genetics has tried to identify specific genes for quantitative traits, called quantitative trait loci (QTLs). The QTL concept suggests that complex personality traits or dimensions are not attributable to single genes, but to multiple interacting genes ({15:Reif and Lesch, 2003)}. {2:Fullerton et al. (2003)} stated that psychologists were in agreement that the wide variation in human personalities can be explained by a small number of personality factors, including neuroticism (a measure of emotional stability), which manifests at one extreme as anxiety, depression, moodiness, low self-esteem, and diffidence. They cited a number of studies that had described a relationship between high scores on measures of neuroticism and major depressive disorder. They also noted that theoretical studies had suggested that large samples of randomly ascertained sibs could be used to ascertain phenotypically extreme individuals and thereby increase power to detect genetic linkage in complex traits. See also panic disorder (PAND1; {167870}), which is a subtype of anxiety disorder.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

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Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

Last Updated: 15 Feb 2013

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

http://www.adaa.org

Last Updated: 15 Feb 2013

View Details
Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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General Resources

The 504 Plan for Selective Mutism: A Social Anxiety Disorder

Preschool - grade 12 school based accommodation plan

Updated 26 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anxiety" returned 2849 free, full-text research articles on human participants. First 3 results:

Does anxiety predict the use of urgent care by people with long term conditions? A systematic review with meta-analysis.
 

Author(s): Claire Blakeley, Amy Blakemore, Cheryl Hunter, Else Guthrie, Barbara Tomenson, Chris Dickens

Journal: J Psychosom Res. 2014 Sep;77(3):232-9.

 

The role of anxiety in the use of urgent care in people with long term conditions is not fully understood. A systematic review was conducted with meta-analysis to examine the relationship between anxiety and future use of urgent healthcare among individuals with one of four long term ...

Last Updated: 23 Aug 2014

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Relationships of diabetes-specific emotional distress, depression, anxiety, and overall well-being with HbA1c in adult persons with type 1 diabetes.
 

Author(s): Ragnhild Bjarkøy Strandberg, Marit Graue, Tore Wentzel-Larsen, Mark Peyrot, Berit Rokne

Journal: J Psychosom Res. 2014 Sep;77(3):174-9.

 

Emotional problems are common in adults with diabetes, and knowledge about how different indicators of emotional problems are related with glycemic control is required. The aim was to examine the relationships of diabetes-specific emotional distress, depression, anxiety, and overall ...

Last Updated: 23 Aug 2014

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Attachment anxiety predicts IL-6 and length of hospital stay in coronary artery bypass graft surgery (CABG) patients.
 

Author(s): Tara Kidd, Lydia Poole, Elizabeth Leigh, Amy Ronaldson, Marjan Jahangiri, Andrew Steptoe

Journal: J Psychosom Res. 2014 Aug;77(2):155-7.

 

The mechanisms underlying the association between adult attachment and health are not well understood. In the current study, we investigated the relationship between attachment anxiety, attachment avoidance, inflammation, and length of hospital stay in coronary artery bypass graft ...

Last Updated: 1 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anxiety" returned 335 free, full-text review articles on human participants. First 3 results:

Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders.
 

Author(s): Martin A Katzman, Pierre Bleau, Pierre Blier, Pratap Chokka, Kevin Kjernisted, Michael Van Ameringen, , Martin M Antony, Stéphane Bouchard, Alain Brunet, Martine Flament, Sophie Grigoriadis, Sandra Mendlowitz, Kieron O'Connor, Kiran Rabheru, Peggy M A Richter, Melisa Robichaud, John R Walker

Journal: BMC Psychiatry. 2014 ;14 Suppl 1():S1.

 

Anxiety and related disorders are among the most common mental disorders, with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are under-diagnosed and under-treated.

Last Updated: 1 Aug 2014

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Protocol for a systematic review and meta-analysis of cognitive-behavioural therapy for social anxiety disorder in psychosis.
 

Author(s): Maria Michail, Max Birchwood, Lynda Tait

Journal:

 

Social anxiety is among the most prevalent and debilitating affective disturbances manifest in people with psychosis. It is usually accompanied by high levels of depression and leads to significant social disability, lower quality of life and poorer prognosis as it raises the possibility ...

Last Updated: 23 Jun 2014

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Depression and anxiety predict health-related quality of life in chronic obstructive pulmonary disease: systematic review and meta-analysis.
 

Author(s): Amy Blakemore, Chris Dickens, Else Guthrie, Peter Bower, Evangelos Kontopantelis, Cara Afzal, Peter A Coventry

Journal:

 

The causal association between depression, anxiety, and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD) is unclear. We therefore conducted a systematic review of prospective cohort studies that measured depression, anxiety, and HRQoL in COPD.

Last Updated: 30 May 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Brief Behavioral Treatment for Anxiety in Young Children
 

Status: Recruiting

Condition Summary: Obsessive-compulsive Disorder; Social Phobia; Generalized Anxiety Disorder; Specific Phobia; Separation Anxiety Disorder; Selective Mutism; Anxiety Disorder, Not Otherwise Specified

 

Last Updated: 15 Sep 2014

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Last Updated: 14 Sep 2012

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Brain Markers of Anxiety Disorders and SSRI/CBT Treatment in Children and Adolescents
 

Status: Recruiting

Condition Summary: Social Phobia; Generalized Anxiety Disorder; Separation Anxiety Disorder

 

Last Updated: 23 Nov 2011

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