Anxiety

Common Name(s)

Anxiety

Human personality is shaped by genetic and environmental factors, and evidence suggests that the genetic component is highly complex, polygenic, and epistatic. Genetic factors are thought to contribute to 40 to 60% of trait variance. Molecular genetics has tried to identify specific genes for quantitative traits, called quantitative trait loci (QTLs). The QTL concept suggests that complex personality traits or dimensions are not attributable to single genes, but to multiple interacting genes ({15:Reif and Lesch, 2003}). {2:Fullerton et al. (2003)} stated that psychologists were in agreement that the wide variation in human personalities can be explained by a small number of personality factors, including neuroticism (a measure of emotional stability), which manifests at one extreme as anxiety, depression, moodiness, low self-esteem, and diffidence. They cited a number of studies that had described a relationship between high scores on measures of neuroticism and major depressive disorder. They also noted that theoretical studies had suggested that large samples of randomly ascertained sibs could be used to ascertain phenotypically extreme individuals and thereby increase power to detect genetic linkage in complex traits. See also panic disorder (PAND1; {167870}), which is a subtype of anxiety disorder.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

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Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

Last Updated: 24 Jun 2015

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anxiety" for support, advocacy or research.

Logo
Anxiety and Depression Association of America

Our mission is to promote the prevention, treatment, and cure of anxiety, depression, and stress-related disorders through education, practice, and research.

http://www.adaa.org

Last Updated: 24 Jun 2015

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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General Resources

The 504 Plan for Selective Mutism: A Social Anxiety Disorder

Preschool - grade 12 school based accommodation plan

Updated 26 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anxiety" returned 4415 free, full-text research articles on human participants. First 3 results:

Usage of perioperative anxiety neuromarker for improving the quality of life of a patient operated on for critical stenosis of the internal carotid artery.
 

Author(s): Mariusz Trystuła, Paweł Półrola, Juri Kropotov

Journal: Ann Agric Environ Med. 2016 12;23(4):612-617.

 

The aim of the study was to find a neuromarker of perioperative anxiety in a patient with critical carotid stenosis through the use of neuromarkers in Quantitative EEG (QEEG) and Event Related Potentials (ERPs). The indirect purpose of the research was evaluation of improvement in ...

Last Updated: 29 Dec 2016

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Anxiety and depression symptoms among caregivers of care-recipients with subjective cognitive decline and cognitive impairment.
 

Author(s): Xiaoniu Liang, Qihao Guo, Jianfeng Luo, Fang Li, Ding Ding, Qianhua Zhao, Zhen Hong

Journal:

 

Caregivers of care-recipients with mild cognitive impairment (MCI) or dementia experience high caregiver burden; however, the psychiatric burden of caregivers of care-recipients with subjective cognitive decline (SCD) has not been investigated. We aimed to explore the prevalence of ...

Last Updated: 7 Oct 2016

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Evaluation of children's dental anxiety levels at a kindergarten and at a dental clinic.
 

Author(s): Gulser Kilinç, Aynur Akay, Ece Eden, Nilgün Sevinç, Hülya Ellidokuz

Journal:

 

This study evaluated the dental anxiety levels of preschool children at a kindergarten and at a dental clinic. The anxiety levels of ninety 4-6-year-old (4.99 ± 0.81) preschool children were evaluated according to pulse rates, the facial image scale (FIS), the Venham picture test ...

Last Updated: 25 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anxiety" returned 608 free, full-text review articles on human participants. First 3 results:

Guidelines for dementia or Parkinson's disease with depression or anxiety: a systematic review.
 

Author(s): Zahra Goodarzi, Bria Mele, Selynne Guo, Heather Hanson, Nathalie Jette, Scott Patten, Tamara Pringsheim, Jayna Holroyd-Leduc

Journal:

 

Depression and anxiety remain under-diagnosed and under-treated in those with neurologic diseases such as dementia or Parkinson's Disease (PD). Our objectives were to first, to provide a synthesis of high quality guidelines available for the identification and management of depression ...

Last Updated: 26 Nov 2016

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Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome.
 

Author(s): Tao Yang, Huan Zhao, Changbo Lu, Xiaoyu Li, Yingli Xie, Hao Fu, Hui Xu

Journal: Neural Plast.. 2016 ;2016():9353929.

 

Fragile X syndrome (FXS) is an inheritable neuropsychological disease caused by expansion of the CGG trinucleotide repeat affecting the fmr1 gene on X chromosome, resulting in silence of the fmr1 gene and failed expression of FMRP. Patients with FXS suffer from cognitive impairment, ...

Last Updated: 30 May 2016

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Diagnostic accuracy of the Depression subscale of the Hospital Anxiety and Depression Scale (HADS-D) for detecting major depression: protocol for a systematic review and individual patient data meta-analyses.
 

Author(s): Brett D Thombs, Andrea Benedetti, Lorie A Kloda, Brooke Levis, Marleine Azar, Kira E Riehm, Nazanin Saadat, Pim Cuijpers, Simon Gilbody, John P A Ioannidis, Dean McMillan, Scott B Patten, Ian Shrier, Russell J Steele, Roy C Ziegelstein, Carmen G Loiselle, Melissa Henry, Zahinoor Ismail, Nicholas Mitchell, Marcello Tonelli

Journal:

 

The Depression subscale of the Hospital Anxiety and Depression Scale (HADS-D) has been recommended for depression screening in medically ill patients. Many existing HADS-D studies have used exploratory methods to select optimal cut-offs. Often, these studies report results from a ...

Last Updated: 14 Apr 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 29 Jun 2016

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Elective Coronary Angiography and Anxiety Study
 

Status: Recruiting

Condition Summary: Anxiety

 

Last Updated: 8 Aug 2016

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Last Updated: 23 Feb 2016

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