Anorexia nervosa 1

Common Name(s)

Anorexia nervosa 1

Eating disorders are characterized by severe disturbances in eating behavior that typically have onset during late adolescence and early adulthood. Three major types are recognized: anorexia nervosa (AN), bulimia nervosa (BN; {607499}), and eating disorder not otherwise specified (EDNOS). AN is characterized by obsessive fear of weight gain, severely restricted eating, and low body weight. In women, AN has the highest mortality among the psychiatric disorders ({11:Sullivan, 1995}). AN is divided into 2 clinical subtypes, restricting anorexia nervosa (RAN) and binge-eating/purging anorexia nervosa (BPAN). BN can occur at any body weight and is characterized by binge-eating and compensatory weight-loss behaviors. Family studies have indicated an increased prevalence of eating disorders in relatives of probands with AN ({8:Lilenfeld et al., 1998}), and twin studies ({7:Holland et al., 1984}; {13:Wade et al., 2000}) have estimated concordance rates for monozygotic twins with AN to be 52 to 56%, whereas concordance rates for dizygotic twins with AN have been estimated to be 5 to 11% ({6:Grice et al., 2002}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anorexia nervosa 1" for support, advocacy or research.

National Association Anorexia Nervosa & Associated Disorders, Inc.

ANAD advocates for the development of healthy attitudes, bodies, and behaviors. ANAD promotes eating disorder awareness, prevention and recovery through supporting, educating, and connecting individuals, families and professionals.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anorexia nervosa 1" for support, advocacy or research.

National Association Anorexia Nervosa & Associated Disorders, Inc.

ANAD advocates for the development of healthy attitudes, bodies, and behaviors. ANAD promotes eating disorder awareness, prevention and recovery through supporting, educating, and connecting individuals, families and professionals.

http://www.anad.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anorexia nervosa 1" returned 12 free, full-text research articles on human participants. First 3 results:

Severe diabetic ketoacidosis in combination with starvation and anorexia nervosa at onset of type 1 diabetes: a case report.
 

Author(s): Daniel Espes, Joakim Engström, Henrik Reinius, Per-Ola Carlsson

Journal: Ups. J. Med. Sci.. 2013 May;118(2):130-3.

 

We here report a case of diabetic ketoacidosis at onset of type 1 diabetes after a prolonged period of starvation due to anorexia nervosa. A 53-year-old female with a history of anorexia nervosa was admitted to the psychiatric clinic due to psychotic behaviour and inability to take ...

Last Updated: 10 Apr 2013

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Inhibition of Pref-1 (preadipocyte factor 1) by oestradiol in adolescent girls with anorexia nervosa is associated with improvement in lumbar bone mineral density.
 

Author(s): Alexander T Faje, Pouneh K Fazeli, Debra Katzman, Karen K Miller, Anne Breggia, Clifford J Rosen, Nara Mendes, Madhusmita Misra, Anne Klibanski

Journal: Clin. Endocrinol. (Oxf). 2013 Sep;79(3):326-32.

 

Adolescents with anorexia nervosa (AN) are amenorrheic and have decreased bone mass accrual and low bone mineral density (BMD). The regulation of mesenchymal stem cell differentiation is an important factor governing bone formation. Preadipocyte factor 1 (Pref-1), an inhibitor of ...

Last Updated: 24 Jul 2013

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Marrow fat and preadipocyte factor-1 levels decrease with recovery in women with anorexia nervosa.
 

Author(s): Pouneh K Fazeli, Miriam A Bredella, Lauren Freedman, Bijoy J Thomas, Anne Breggia, Erinne Meenaghan, Clifford J Rosen, Anne Klibanski

Journal: J. Bone Miner. Res.. 2012 Sep;27(9):1864-71.

 

Women with anorexia nervosa (AN) have elevated marrow fat mass despite low visceral and subcutaneous fat depots, which is inversely associated with bone mineral density (BMD). Whether marrow fat mass remains persistently elevated or decreases with recovery from AN is currently unknown. ...

Last Updated: 20 Aug 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anorexia nervosa 1" returned 1 free, full-text review articles on human participants. First 3 results:

[Anorexia nervosa in a patient with type-1 diabetes mellitus].
 

Author(s): J L Luzio, F Matos, M Pena, A Coelho, A Sá, R Conceição, I Nogueira

Journal: Acta Med Port. 1997 Dec;10(12):947-9.

 

Female patient, 21 years of age, with diabetes mellitus type I, admitted due to progressive weight loss, with a recent history of impaired glycemic control, ketosis and amenorrhea for 12 months. Studies were conducted in order to exclude an endocrine or malignant disorder. After nutritional, ...

Last Updated: 13 May 1998

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

IGF-1 and Bone Loss in Women With Anorexia Nervosa
 

Status: Recruiting

Condition Summary: Anorexia Nervosa; Osteopenia; Osteoporosis

 

Last Updated: 17 Mar 2014

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Effects of Anorexia Nervosa on Peak Bone Mass
 

Status: Recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 10 Dec 2013

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