Anorexia nervosa

Common Name(s)

Anorexia nervosa

Anorexia nervosa , commonly known as anorexia, is a serious eating disorder characterized by self-starvation and excessive weight loss. A person with anorexia consumes very little or no food, avoids specific foods, has inappropriate eating habits or rituals, an obsession with becoming or remaining thin, an irrational fear of weight gain, a rigid and excessive exercise program, and generally becomes obsessed with food, calories and body weight. Depression, anxiety, and mood swings are also common. The causes for anorexia are both biological and social and most often related to poor body image. In terms of biology, there have been studies that show some people are genetically predisposed to develop anorexia. Socially, males and females may develop anorexia because of their cultural norms or the media's portrayal of an unrealistic "ideal" body type. Women are significantly more likely to develop anorexia, although a small percentage of men do as well, which typically onsets in adolescence. Some health consequences of anorexia may include a menstrual cycle that has stopped, muscle loss and weakness, dehydration, slow heart rate and low blood pressure, dry and brittle hair, a yellowing of the skin, rapid weight loss, swollen cheeks, and fatigue. Treatment for individuals with anorexia includes a combination of restoring the person to normal body weight, treating any additional psychological conditions, and promoting a more positive body image. This will include a combination of dietary supplements, therapy, and generally some medications. Treatment is tailored to the specific individual according to their particular problems, strengths and needs. Early diagnosis and intervention is key to recovery and is crucial to prevent or lessen the severity of complications that can occur due to long-term anorexia. If you or someone you know may be suffering from anorexia, it is best to contact your doctor or a trained professional for help.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anorexia nervosa" for support, advocacy or research.

National Association Anorexia Nervosa & Associated Disorders, Inc.

ANAD advocates for the development of healthy attitudes, bodies, and behaviors. ANAD promotes eating disorder awareness, prevention and recovery through supporting, educating, and connecting individuals, families and professionals.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anorexia nervosa" for support, advocacy or research.

National Association Anorexia Nervosa & Associated Disorders, Inc.

ANAD advocates for the development of healthy attitudes, bodies, and behaviors. ANAD promotes eating disorder awareness, prevention and recovery through supporting, educating, and connecting individuals, families and professionals.

http://www.anad.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anorexia nervosa" returned 647 free, full-text research articles on human participants. First 3 results:

Parent-focused treatment for adolescent anorexia nervosa: a study protocol of a randomised controlled trial.
 

Author(s): Elizabeth K Hughes, Daniel Le Grange, Andrew Court, Michele S M Yeo, Stephanie Campbell, Erica Allan, Ross D Crosby, Katharine L Loeb, Susan M Sawyer

Journal:

 

Family-based treatment is an efficacious outpatient intervention for medically stable adolescents with anorexia nervosa. Previous research suggests family-based treatment may be more effective for some families when parents and adolescents attend separate therapy sessions compared ...

Last Updated: 16 Apr 2014

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Differential methylation of the oxytocin receptor gene in patients with anorexia nervosa: a pilot study.
 

Author(s): Youl-Ri Kim, Jeong-Hyun Kim, Mi Jeong Kim, Janet Treasure

Journal:

 

Recent studies in patients with anorexia nervosa suggest that oxytocin may be involved in the pathophysiology of anorexia nervosa. We examined whether there was evidence of variation in methylation status of the oxytocin receptor (OXTR) gene in patients with anorexia nervosa that ...

Last Updated: 13 Feb 2014

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Gut microeukaryotes during anorexia nervosa: a case report.
 

Author(s): Nina Gouba, Didier Raoult, Michel Drancourt

Journal:

 

Few studies have focused on eukaryote community in the human gut. Here, the diversity of microeukaryotes in the gut microbiota of an anorexic patient was investigated using molecular and culture approaches.

Last Updated: 17 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anorexia nervosa" returned 55 free, full-text review articles on human participants. First 3 results:

Anorexia nervosa and bone.
 

Author(s): Madhusmita Misra, Anne Klibanski

Journal: J. Endocrinol.. 2014 Jun;221(3):R163-76.

 

Anorexia nervosa (AN) is a condition of severe low weight that is associated with low bone mass, impaired bone structure, and reduced bone strength, all of which contribute to increased fracture risk. Adolescents with AN have decreased rates of bone accrual compared with normal-weight ...

Last Updated: 6 Jun 2014

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[Pathogenesis of anorexia nervosa. Neurobiological risk factors and possible endophenotypes].
 

Author(s): Bea Pászthy, Mária Törzsök-Sonnevend

Journal: Orv Hetil. 2014 Jan;155(4):124-31.

 

Anorexia nervosa is a serious, chronical state of illness which often starts in childhood or adolescence and has serious consequences on the quality of life. This review focuses on the heterogenity of the disease with emphasis on special diagnostic implications in case of childhood ...

Last Updated: 20 Jan 2014

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Anorexia nervosa, obesity and bone metabolism.
 

Author(s): Madhusmita Misra, Anne Klibanski

Journal: Pediatr Endocrinol Rev. 2013 Sep;11(1):21-33.

 

Anorexia nervosa and obesity are conditions at the extreme ends of the nutritional spectrum, associated with marked reductions versus increases respectively in body fat content. Both conditions are also associated with an increased risk for fractures. In anorexia nervosa, body composition ...

Last Updated: 1 Oct 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Anorexia Nervosa Genetics Initiative
 

Status: Recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 6 Aug 2014

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Effects of Anorexia Nervosa on Peak Bone Mass
 

Status: Recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 8 Oct 2014

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Body Image Therapy in Anorexia Nervosa
 

Status: Not yet recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 20 Sep 2011

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