Anorexia nervosa

Common Name(s)

Anorexia nervosa

Anorexia nervosa , commonly known as anorexia, is a serious eating disorder characterized by self-starvation and excessive weight loss. A person with anorexia consumes very little or no food, avoids specific foods, has inappropriate eating habits or rituals, an obsession with becoming or remaining thin, an irrational fear of weight gain, a rigid and excessive exercise program, and generally becomes obsessed with food, calories and body weight. Depression, anxiety, and mood swings are also common. The causes for anorexia are both biological and social and most often related to poor body image. In terms of biology, there have been studies that show some people are genetically predisposed to develop anorexia. Socially, males and females may develop anorexia because of their cultural norms or the media's portrayal of an unrealistic "ideal" body type. Women are significantly more likely to develop anorexia, although a small percentage of men do as well, which typically onsets in adolescence. Some health consequences of anorexia may include a menstrual cycle that has stopped, muscle loss and weakness, dehydration, slow heart rate and low blood pressure, dry and brittle hair, a yellowing of the skin, rapid weight loss, swollen cheeks, and fatigue. Treatment for individuals with anorexia includes a combination of restoring the person to normal body weight, treating any additional psychological conditions, and promoting a more positive body image. This will include a combination of dietary supplements, therapy, and generally some medications. Treatment is tailored to the specific individual according to their particular problems, strengths and needs. Early diagnosis and intervention is key to recovery and is crucial to prevent or lessen the severity of complications that can occur due to long-term anorexia. If you or someone you know may be suffering from anorexia, it is best to contact your doctor or a trained professional for help.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anorexia nervosa" for support, advocacy or research.

National Association Anorexia Nervosa & Associated Disorders, Inc.

ANAD advocates for the development of healthy attitudes, bodies, and behaviors. ANAD promotes eating disorder awareness, prevention and recovery through supporting, educating, and connecting individuals, families and professionals.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anorexia nervosa" for support, advocacy or research.

National Association Anorexia Nervosa & Associated Disorders, Inc.

ANAD advocates for the development of healthy attitudes, bodies, and behaviors. ANAD promotes eating disorder awareness, prevention and recovery through supporting, educating, and connecting individuals, families and professionals.

http://www.anad.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anorexia nervosa" returned 778 free, full-text research articles on human participants. First 3 results:

Association of the glucocorticoid receptor gene polymorphisms and their interaction with stressful life events in Polish adolescent girls with anorexia nervosa.
 

Author(s): Monika Dmitrzak-Weglarz, Aleksandra Szczepankiewicz, Agnieszka Slopien, Marta Tyszkiewicz, Malgorzata Maciukiewicz, Dorota Zaremba, Joanna Twarowska-Hauser

Journal: Psychiatr Danub. 2016 Mar;28(1):51-7.

 

Disturbances in stress response mechanisms and hypothalamic-pituitary-adrenal axis (HPA) functioning are considered important factors involved in the pathophysiology of anorexia nervosa (AN). Thus, genetic variations in the end effector of HPA - glucocorticoid receptor gene and relationships ...

Last Updated: 4 Mar 2016

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Neural mechanisms supporting maladaptive food choices in anorexia nervosa.
 

Author(s): Karin Foerde, Joanna E Steinglass, Daphna Shohamy, B Timothy Walsh

Journal: Nat. Neurosci.. 2015 Nov;18(11):1571-3.

 

People routinely make poor choices, despite knowledge of negative consequences. The authors found that individuals with anorexia nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about ...

Last Updated: 28 Oct 2015

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Prevalence of abnormal liver function tests and comorbid psychiatric disorders among patients with anorexia nervosa and eating disorders not otherwise specified in the anorexia nervosa DSM-IV criteria.
 

Author(s): Kye Hock Robin Goh, Ee Lian Lee

Journal: Singapore Med J. 2015 Sep;56(9):488-92.

 

Anorexia nervosa (AN) and eating disorders not otherwise specified (EDNOS) are on the rise in Singapore. Abnormal liver function tests have been reported for up to 12.2% of patients with AN. These patients are also known to present with comorbid psychiatric disorders. This study aims ...

Last Updated: 9 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anorexia nervosa" returned 78 free, full-text review articles on human participants. First 3 results:

[EDNOS is an eating disorder of clinical relevance, on a par with anorexia and bulimia nervosa].
 

Author(s): A E Dingemans, E F van Furth

Journal: Tijdschr Psychiatr. 2015 ;57(4):258-64.

 

The category 'eating disorder 'not otherwise specified'' (EDNOS) in DSM-IV is restricted to eating disorders of clinical severity that do not completely fulfil the criteria for anorexia and bulimia nervosa. The EDNOS category is, by definition, often regarded as a a residual category ...

Last Updated: 23 Apr 2015

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Myocardial changes in a patient with anorexia nervosa: a case report and review of literature.
 

Author(s): Ihab Lamzabi, Sahr Syed, Vijaya B Reddy, Richa Jain, Aparna Harbhajanka, Ponni Arunkumar

Journal: Am. J. Clin. Pathol.. 2015 May;143(5):734-7.

 

Anorexia nervosa (AN) is an eating disorder with high mortality and morbidity. Much of the mortality is related to cardiovascular complications manifesting with electrocardiogram abnormalities and morphologic abnormalities documented on ultrasound. However, gross and histologic abnormalities ...

Last Updated: 15 Apr 2015

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The potential of technology-based psychological interventions for anorexia and bulimia nervosa: a systematic review and recommendations for future research.
 

Author(s): Sandra Schlegl, Carolina B├╝rger, Luise Schmidt, Nirmal Herbst, Ulrich Voderholzer

Journal:

 

Previous studies have shown an unmet need in the treatment of eating disorders. In the last decade, interest in technology-based interventions (TBIs) (including computer- and Internet-based interventions [CBIs] or mobile interventions) for providing evidence-based therapies to individuals ...

Last Updated: 4 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Anorexia Nervosa Genetics Initiative
 

Status: Recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 7 Oct 2015

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Effects of Anorexia Nervosa on Peak Bone Mass
 

Status: Recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 30 Jun 2015

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Changing Habits in Anorexia Nervosa: Novel Treatment Development
 

Status: Recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 19 Oct 2015

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