Anorexia nervosa

Common Name(s)

Anorexia nervosa

Anorexia nervosa , commonly known as anorexia, is a serious eating disorder characterized by self-starvation and excessive weight loss. A person with anorexia consumes very little or no food, avoids specific foods, has inappropriate eating habits or rituals, an obsession with becoming or remaining thin, an irrational fear of weight gain, a rigid and excessive exercise program, and generally becomes obsessed with food, calories and body weight. Depression, anxiety, and mood swings are also common. The causes for anorexia are both biological and social and most often related to poor body image. In terms of biology, there have been studies that show some people are genetically predisposed to develop anorexia. Socially, males and females may develop anorexia because of their cultural norms or the media's portrayal of an unrealistic "ideal" body type. Women are significantly more likely to develop anorexia, although a small percentage of men do as well, which typically onsets in adolescence. Some health consequences of anorexia may include a menstrual cycle that has stopped, muscle loss and weakness, dehydration, slow heart rate and low blood pressure, dry and brittle hair, a yellowing of the skin, rapid weight loss, swollen cheeks, and fatigue. Treatment for individuals with anorexia includes a combination of restoring the person to normal body weight, treating any additional psychological conditions, and promoting a more positive body image. This will include a combination of dietary supplements, therapy, and generally some medications. Treatment is tailored to the specific individual according to their particular problems, strengths and needs. Early diagnosis and intervention is key to recovery and is crucial to prevent or lessen the severity of complications that can occur due to long-term anorexia. If you or someone you know may be suffering from anorexia, it is best to contact your doctor or a trained professional for help.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anorexia nervosa" for support, advocacy or research.

National Association Anorexia Nervosa & Associated Disorders, Inc.

ANAD advocates for the development of healthy attitudes, bodies, and behaviors. ANAD promotes eating disorder awareness, prevention and recovery through supporting, educating, and connecting individuals, families and professionals.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anorexia nervosa" for support, advocacy or research.

National Association Anorexia Nervosa & Associated Disorders, Inc.

ANAD advocates for the development of healthy attitudes, bodies, and behaviors. ANAD promotes eating disorder awareness, prevention and recovery through supporting, educating, and connecting individuals, families and professionals.

http://www.anad.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anorexia nervosa" returned 820 free, full-text research articles on human participants. First 3 results:

Saccadic Eye Movements in Anorexia Nervosa.
 

Author(s): Andrea Phillipou, Susan Lee Rossell, Caroline Gurvich, Matthew Edward Hughes, David Jonathan Castle, Richard Grant Nibbs, Larry Allen Abel

Journal:

 

Anorexia Nervosa (AN) has a mortality rate among the highest of any mental illness, though the factors involved in the condition remain unclear. Recently, the potential neurobiological underpinnings of the condition have become of increasing interest. Saccadic eye movement tasks have ...

Last Updated: 25 Mar 2016

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A Randomised Controlled Trial of Neuronavigated Repetitive Transcranial Magnetic Stimulation (rTMS) in Anorexia Nervosa.
 

Author(s): Jessica McClelland, Maria Kekic, Natali Bozhilova, Steffen Nestler, Tracy Dew, Frederique Van den Eynde, Anthony S David, Katya Rubia, Iain C Campbell, Ulrike Schmidt

Journal:

 

Anorexia nervosa (AN) is associated with morbid fear of fatness, extreme food restriction and altered self-regulation. Neuroimaging data implicate fronto-striatal circuitry, including the dorsolateral prefrontal cortex (DLPFC).

Last Updated: 24 Mar 2016

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Association of the glucocorticoid receptor gene polymorphisms and their interaction with stressful life events in Polish adolescent girls with anorexia nervosa.
 

Author(s): Monika Dmitrzak-Weglarz, Aleksandra Szczepankiewicz, Agnieszka Slopien, Marta Tyszkiewicz, Malgorzata Maciukiewicz, Dorota Zaremba, Joanna Twarowska-Hauser

Journal: Psychiatr Danub. 2016 Mar;28(1):51-7.

 

Disturbances in stress response mechanisms and hypothalamic-pituitary-adrenal axis (HPA) functioning are considered important factors involved in the pathophysiology of anorexia nervosa (AN). Thus, genetic variations in the end effector of HPA - glucocorticoid receptor gene and relationships ...

Last Updated: 4 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anorexia nervosa" returned 82 free, full-text review articles on human participants. First 3 results:

[Anorexia nervosa and adolescents].
 

Author(s): A A van Elburg, U N Danner

Journal: Tijdschr Psychiatr. 2015 ;57(12):923-7.

 

Anorexia nervosa (AN), which is the most serious of the eating disorders, starts earlier in life and often continues into adulthood.

Last Updated: 5 Jan 2016

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Dimensions of emotion dysregulation in anorexia nervosa and bulimia nervosa: A conceptual review of the empirical literature.
 

Author(s): Jason M Lavender, Stephen A Wonderlich, Scott G Engel, Kathryn H Gordon, Walter H Kaye, James E Mitchell

Journal: Clin Psychol Rev. 2015 Aug;40():111-22.

 

Several existing conceptual models and psychological interventions address or emphasize the role of emotion dysregulation in eating disorders. The current article uses Gratz and Roemer's (2004) multidimensional model of emotion regulation and dysregulation as a clinically relevant ...

Last Updated: 15 Aug 2015

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[EDNOS is an eating disorder of clinical relevance, on a par with anorexia and bulimia nervosa].
 

Author(s): A E Dingemans, E F van Furth

Journal: Tijdschr Psychiatr. 2015 ;57(4):258-64.

 

The category 'eating disorder 'not otherwise specified'' (EDNOS) in DSM-IV is restricted to eating disorders of clinical severity that do not completely fulfil the criteria for anorexia and bulimia nervosa. The EDNOS category is, by definition, often regarded as a a residual category ...

Last Updated: 23 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Anorexia Nervosa Genetics Initiative
 

Status: Recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 17 May 2016

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Effects of Anorexia Nervosa on Peak Bone Mass
 

Status: Recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 26 Jul 2016

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Changing Habits in Anorexia Nervosa: Novel Treatment Development
 

Status: Recruiting

Condition Summary: Anorexia Nervosa

 

Last Updated: 19 May 2016

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