Alcohol dependence

Common Name(s)

Alcohol dependence, Alcoholism, Alcohol addiction

Alcoholism means a person is physically or mentally dependent on alcohol. It is a serious medical condition. People with alcoholism often struggle to live normal lives. They may try to hide their problem. Yet drinking too much alcohol can lead to poor life choices such as drinking and driving. Alcohol can cause serious health consequences. Symptoms of alcoholism may include not being able to stop drinking or having a hard time controlling how much you drink, needing more alcohol to feel good, spending a lot of time drinking and recovering from drinking, giving up other activities so you can drink, and withdrawal symptoms if you stop drinking or wait too long between drinks. Withdrawal symptoms may include feeling sick to your stomach, sweating, shakiness and anxiety. Alcoholism may interfere with your relationships and your ability to perform your job.

Alcoholism may be caused by a variety of factors. Genetic, psychological, social and environmental factors may all be part of the cause. Risk factors include steady drinking over time or binge drinking on a regular basis, starting to drink alcohol at a young age, a family history of alcoholism, and suffering from depression, bipolar disorder or anxiety. Alcoholism increases your risk for developing liver damage (cirrhosis), digestive problems, heart problems, sexual dysfunction, birth defects, bone loss, neurological complications and complications with diabetes. Alcoholism can weaken your immune system and increase your risk of certain cancers. Talk to your doctor if you or a family member may have an alcohol addiction. They may ask you a series of questions to determine if you are addicted to alcohol and to rule out other conditions. There are a variety of treatments to help you stop drinking including both inpatient and outpatient programs and private and group counseling. Your doctor can help you decide the best treatment plan for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

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National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

Last Updated: 8 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

Logo
National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

https://ncadd.org/

Last Updated: 8 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alcohol dependence" returned 760 free, full-text research articles on human participants. First 3 results:

Positive Selection on Loci Associated with Drug and Alcohol Dependence.
 

Author(s): Brooke Sadler, Gabe Haller, Howard Edenberg, Jay Tischfield, Andy Brooks, John Kramer, Marc Schuckit, John Nurnberger, Alison Goate

Journal:

 

Much of the evolution of human behavior remains a mystery, including how certain disadvantageous behaviors are so prevalent. Nicotine addiction is one such phenotype. Several loci have been implicated in nicotine related phenotypes including the nicotinic receptor gene clusters (CHRNs) ...

Last Updated: 14 Aug 2015

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Cue reactivity and its relation to craving and relapse in alcohol dependence: a combined laboratory and field study.
 

Author(s): Jurriaan Witteman, Hans Post, Mika Tarvainen, Avalon de Bruijn, Elizabeth De Sousa Fernandes Perna, Johannes G Ramaekers, Reinout W Wiers

Journal: Psychopharmacology (Berl.). 2015 Oct;232(20):3685-96.

 

The present study investigated the nature of physiological cue reactivity and craving in response to alcohol cues among alcohol-dependent patients (N = 80) who were enrolled in detoxification treatment. Further, the predictive value with regard to future drinking of both the magnitude ...

Last Updated: 9 Sep 2015

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Alcohol dependence and treatment utilization in Europe - a representative cross-sectional study in primary care.
 

Author(s): Jürgen Rehm, Allaman Allamani, Zsuzsanna Elekes, Andrzej Jakubczyk, Jakob Manthey, Charlotte Probst, Pierluigi Struzzo, Roberto Della Vedova, Antoni Gual, Marcin Wojnar

Journal:

 

Alcohol dependence (AD) in Europe is prevalent and causes considerable health burden. Recognition by general practitioners (GPs) and provision of or referral to treatment may contribute to reduce this burden. This paper studied AD prevalence in varying European primary care settings ...

Last Updated: 29 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alcohol dependence" returned 88 free, full-text review articles on human participants. First 3 results:

ALCOHOL DEPENDENCE--NEUROBIOLOGY AND TREATMENT.
 

Author(s): Agnieszka Michalak, Grazyna Biała

Journal: Acta Pol Pharm. ;73(1):3-12.

 

The consequences of alcohol dependence concern serious health care, social and economic problems. The scope of many studies is to better understand mechanisms underlying alcohol addiction in order to work out new, more effective treatment strategies. Alcohol affects many neurotransmission ...

Last Updated: 24 Mar 2016

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Risks and Benefits of Nalmefene in the Treatment of Adult Alcohol Dependence: A Systematic Literature Review and Meta-Analysis of Published and Unpublished Double-Blind Randomized Controlled Trials.
 

Author(s): Clément Palpacuer, Bruno Laviolle, Rémy Boussageon, Jean Michel Reymann, Eric Bellissant, Florian Naudet

Journal:

 

Nalmefene is a recent option in alcohol dependence treatment. Its approval was controversial. We conducted a systematic review and meta-analysis of the aggregated data (registered as PROSPERO 2014:CRD42014014853) to compare the harm/benefit of nalmefene versus placebo or active comparator ...

Last Updated: 23 Dec 2015

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Should naltrexone be the first-line medicine to treat alcohol dependence in Aboriginal and Torres Strait Islander populations? An Australian perspective.
 

Author(s): Jonathan Brett, Rowena Ivers, Michael Doyle, Leanne Lawrence, Kate Conigrave

Journal: Aust Fam Physician. 2015 ;44(11):815-9.

 

There is a pressing need to improve alcohol treatment services for Aboriginal and Torre Strait Islander peoples with alcohol dependence. One component of treatment is the use of medicines including naltrexone and acamprosate. Access to these medicines among the general drinking population ...

Last Updated: 23 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Oxytocin Treatment of Alcohol Dependence
 

Status: Not yet recruiting

Condition Summary: Alcohol Dependence; Alcohol Withdrawal

 

Last Updated: 21 Jul 2015

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Citicoline for Alcohol Dependence
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 20 May 2016

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Treatment for Alcohol Dependence With Gabapentin
 

Status: Not yet recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 11 May 2016

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