Alcohol dependence

Common Name(s)

Alcohol dependence, Alcoholism, Alcohol addiction

Alcoholism means a person is physically or mentally dependent on alcohol. It is a serious medical condition. People with alcoholism often struggle to live normal lives. They may try to hide their problem. Yet drinking too much alcohol can lead to poor life choices such as drinking and driving. Alcohol can cause serious health consequences. Symptoms of alcoholism may include not being able to stop drinking or having a hard time controlling how much you drink, needing more alcohol to feel good, spending a lot of time drinking and recovering from drinking, giving up other activities so you can drink, and withdrawal symptoms if you stop drinking or wait too long between drinks. Withdrawal symptoms may include feeling sick to your stomach, sweating, shakiness and anxiety. Alcoholism may interfere with your relationships and your ability to perform your job.

Alcoholism may be caused by a variety of factors. Genetic, psychological, social and environmental factors may all be part of the cause. Risk factors include steady drinking over time or binge drinking on a regular basis, starting to drink alcohol at a young age, a family history of alcoholism, and suffering from depression, bipolar disorder or anxiety. Alcoholism increases your risk for developing liver damage (cirrhosis), digestive problems, heart problems, sexual dysfunction, birth defects, bone loss, neurological complications and complications with diabetes. Alcoholism can weaken your immune system and increase your risk of certain cancers. Talk to your doctor if you or a family member may have an alcohol addiction. They may ask you a series of questions to determine if you are addicted to alcohol and to rule out other conditions. There are a variety of treatments to help you stop drinking including both inpatient and outpatient programs and private and group counseling. Your doctor can help you decide the best treatment plan for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

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National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

Last Updated: 8 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

Logo
National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

https://ncadd.org/

Last Updated: 8 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alcohol dependence" returned 768 free, full-text research articles on human participants. First 3 results:

Case control study of ANKK1 Taq 1A polymorphism in patients with alcohol dependence classified according to Lesch's typology.
 

Author(s): Agnieszka Samochowiec, Magdalena Chęć, Edyta Kopaczewska, Jerzy Samochowiec, Otto Lesch, Andrzej Jasiewicz, Elżbieta Grochans, Marcin Jabłoński, Przemysław Bieńkowski, Łukasz Kołodziej, Anna Grzywacz

Journal:

 

The aim of this study was to examine the association between the Taq 1A polymorphism of the ANKK1 gene in homogeneous subgroups of patients with alcohol dependence syndrome divided according to Lesch's typology.

Last Updated: 16 May 2016

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Validation of the MINI (DSM IV) Tool for the Assessment of Alcohol Dependence among Young People in Northern Tanzania Using the Alcohol Biomarker Phosphatidylethanol (PEth).
 

Author(s): Joel M Francis, Anders Helander, Saidi H Kapiga, Helen A Weiss, Heiner Grosskurth

Journal:

 

The alcohol dependence section of the Mini International Neuropsychiatric Interview questionnaire (MINI) has not been evaluated in young Africans. We applied the MINI in a cross-sectional study of 202 alcohol users from northern-Tanzania, aged 18-24 years (103 male casual workers ...

Last Updated: 4 Nov 2015

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Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence.
 

Author(s): Mohammed Mamdani, Vernell Williamson, Gowon O McMichael, Tana Blevins, Fazil Aliev, Amy Adkins, Laura Hack, Tim Bigdeli, Andrew D van der Vaart, Bradley Todd Web, Silviu-Alin Bacanu, Gursharan Kalsi, , Kenneth S Kendler, Michael F Miles, Danielle Dick, Brien P Riley, Catherine Dumur, Vladimir I Vladimirov

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Alcohol consumption is known to lead to gene expression changes in the brain. After performing weighted gene co-expression network analyses (WGCNA) on genome-wide mRNA and microRNA (miRNA) expression in Nucleus Accumbens (NAc) of subjects with alcohol dependence (AD; N = 18) and of ...

Last Updated: 19 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alcohol dependence" returned 89 free, full-text review articles on human participants. First 3 results:

Risks and Benefits of Nalmefene in the Treatment of Adult Alcohol Dependence: A Systematic Literature Review and Meta-Analysis of Published and Unpublished Double-Blind Randomized Controlled Trials.
 

Author(s): Clément Palpacuer, Bruno Laviolle, Rémy Boussageon, Jean Michel Reymann, Eric Bellissant, Florian Naudet

Journal:

 

Nalmefene is a recent option in alcohol dependence treatment. Its approval was controversial. We conducted a systematic review and meta-analysis of the aggregated data (registered as PROSPERO 2014:CRD42014014853) to compare the harm/benefit of nalmefene versus placebo or active comparator ...

Last Updated: 23 Dec 2015

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Should naltrexone be the first-line medicine to treat alcohol dependence in Aboriginal and Torres Strait Islander populations? An Australian perspective.
 

Author(s): Jonathan Brett, Rowena Ivers, Michael Doyle, Leanne Lawrence, Kate Conigrave

Journal: Aust Fam Physician. 2015 ;44(11):815-9.

 

There is a pressing need to improve alcohol treatment services for Aboriginal and Torre Strait Islander peoples with alcohol dependence. One component of treatment is the use of medicines including naltrexone and acamprosate. Access to these medicines among the general drinking population ...

Last Updated: 23 Nov 2015

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Efficacy of Medications Approved for the Treatment of Alcohol Dependence and Alcohol Withdrawal Syndrome in Female Patients: A Descriptive Review.
 

Author(s): Roberta Agabio, Pier Paolo Pani, Antonio Preti, Gian Luigi Gessa, Flavia Franconi

Journal: Eur Addict Res. 2016 ;22(1):1-16.

 

The aim of this study was to evaluate whether the number of women recruited for studies to establish the efficacy of medications approved for treatment of alcohol dependence (AD) and of alcohol withdrawal syndrome (AWS) is sufficient to reveal possible gender differences in the response ...

Last Updated: 2 Sep 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Oxytocin Treatment of Alcohol Dependence
 

Status: Recruiting

Condition Summary: Alcohol Dependence; Alcohol Withdrawal

 

Last Updated: 26 May 2016

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Citicoline for Alcohol Dependence
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 21 Jun 2016

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Treatment for Alcohol Dependence With Gabapentin
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 9 Jun 2016

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