Alcohol dependence

Common Name(s)

Alcohol dependence, Alcoholism, Alcohol addiction

Alcoholism means a person is physically or mentally dependent on alcohol. It is a serious medical condition. People with alcoholism often struggle to live normal lives. They may try to hide their problem. Yet drinking too much alcohol can lead to poor life choices such as drinking and driving. Alcohol can cause serious health consequences. Symptoms of alcoholism may include not being able to stop drinking or having a hard time controlling how much you drink, needing more alcohol to feel good, spending a lot of time drinking and recovering from drinking, giving up other activities so you can drink, and withdrawal symptoms if you stop drinking or wait too long between drinks. Withdrawal symptoms may include feeling sick to your stomach, sweating, shakiness and anxiety. Alcoholism may interfere with your relationships and your ability to perform your job.

Alcoholism may be caused by a variety of factors. Genetic, psychological, social and environmental factors may all be part of the cause. Risk factors include steady drinking over time or binge drinking on a regular basis, starting to drink alcohol at a young age, a family history of alcoholism, and suffering from depression, bipolar disorder or anxiety. Alcoholism increases your risk for developing liver damage (cirrhosis), digestive problems, heart problems, sexual dysfunction, birth defects, bone loss, neurological complications and complications with diabetes. Alcoholism can weaken your immune system and increase your risk of certain cancers. Talk to your doctor if you or a family member may have an alcohol addiction. They may ask you a series of questions to determine if you are addicted to alcohol and to rule out other conditions. There are a variety of treatments to help you stop drinking including both inpatient and outpatient programs and private and group counseling. Your doctor can help you decide the best treatment plan for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

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National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

Last Updated: 8 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

Logo
National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

https://ncadd.org/

Last Updated: 8 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alcohol dependence" returned 731 free, full-text research articles on human participants. First 3 results:

Markers of inflammation and mortality in a cohort of patients with alcohol dependence.
 

Author(s): Daniel Fuster, Arantza Sanvisens, Ferran Bolao, Paola Zuluaga, Inmaculada Rivas, Jordi Tor, Robert Muga

Journal: Medicine (Baltimore). 2015 Mar;94(10):e607.

 

Inflammation and intestinal permeability are believed to be paramount features in the development of alcohol-related liver damage. We aimed to assess the impact of 3 surrogate markers of inflammation (anemia, fibrinogen, and ferritin levels) on mid-term mortality of patients with ...

Last Updated: 12 Mar 2015

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SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans.
 

Author(s): Laura D Mathies, GinaMari G Blackwell, Makeda K Austin, Alexis C Edwards, Brien P Riley, Andrew G Davies, Jill C Bettinger

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2015 Mar;112(10):3032-7.

 

Alcohol abuse is a widespread and serious problem. Understanding the factors that influence the likelihood of abuse is important for the development of effective therapies. There are both genetic and environmental influences on the development of abuse, but it has been difficult to ...

Last Updated: 11 Mar 2015

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Assessment of the frequency of the transforming growth factor beta-1 sequence polymorphisms in patients with alcohol dependence syndrome.
 

Author(s): Beata Augustyńska, Aleksander Araszkiewicz, Marcin Woźniak, Tomasz Grzybowski, Katarzyna Skonieczna, Alina Woźniak, Magdalena Żyła

Journal: Acta Biochim. Pol.. 2015 ;62(1):63-7.

 

Alcohol abuse is one of the most significant factors in the development of liver fibrosis. The pathomechanism of liver fibrosis is the same regardless of its etiology. Fibrosis is a sign of an imbalance between the synthesis of the extracellular matrix components and their degradation. ...

Last Updated: 27 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alcohol dependence" returned 83 free, full-text review articles on human participants. First 3 results:

[Comorbidity of alcohol dependence with other psychiatric disorders. Part II. Pathogenesis and treatment].
 

Author(s): Anna Klimkiewicz, Jakub Klimkiewicz, Andrzej Jakubczyk, Ilona Kieres-Salomoński, Marcin Wojnar

Journal: Psychiatr. Pol.. ;49(2):277-94.

 

Co-occurrence of alcohol dependence with other mental disorders is very common, being important cause of diagnostic and therapeutic difficulties. There is a lack of systemic solutions in mental health care dedicated to the patients with dual diagnosis. The literature on the topic ...

Last Updated: 23 Jun 2015

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[Comorbidity of alcohol dependence with other psychiatric disorders. Part I. Epidemiology of dual diagnosis].
 

Author(s): Anna Klimkiewicz, Jakub Klimkiewicz, Andrzej Jakubczyk, Ilona Kieres-Salomoński, Marcin Wojnar

Journal: Psychiatr. Pol.. ;49(2):265-75.

 

The paper is a review of the literature on the comorbidity of alcohol dependence with other psychiatric disorders. A condition when alcohol dependence is accompanied by another mental disorder is much more common than it is commonly believed. It is estimated that more than one third ...

Last Updated: 23 Jun 2015

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Novel strategies to treat alcohol dependence with sodium oxybate according to clinical practice.
 

Author(s): F Caputo, A Mirijello, M Cibin, A Mosti, M Ceccanti, M Domenicali, M Bernardi, I Maremmani, G Addolorato,

Journal: Eur Rev Med Pharmacol Sci. 2015 Apr;19(7):1315-20.

 

The treatment of alcohol dependence (AD) with sodium oxybate (SMO) was introduced in Italy and Austria more than 20 years and 15 years ago respectively, and it is now widely employed. In addition to the data obtained from clinical trials, little information is available on specific ...

Last Updated: 27 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Oxytocin Treatment of Alcohol Dependence
 

Status: Not yet recruiting

Condition Summary: Alcohol Dependence; Alcohol Withdrawal

 

Last Updated: 21 Jul 2015

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Citicoline for Alcohol Dependence
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 2 Nov 2015

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Varenicline for Alcohol Dependence
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 14 Sep 2010

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