Alcohol dependence

Common Name(s)

Alcohol dependence, Alcoholism, Alcohol addiction

Alcoholism means a person is physically or mentally dependent on alcohol. It is a serious medical condition. People with alcoholism often struggle to live normal lives. They may try to hide their problem. Yet drinking too much alcohol can lead to poor life choices such as drinking and driving. Alcohol can cause serious health consequences. Symptoms of alcoholism may include not being able to stop drinking or having a hard time controlling how much you drink, needing more alcohol to feel good, spending a lot of time drinking and recovering from drinking, giving up other activities so you can drink, and withdrawal symptoms if you stop drinking or wait too long between drinks. Withdrawal symptoms may include feeling sick to your stomach, sweating, shakiness and anxiety. Alcoholism may interfere with your relationships and your ability to perform your job.

Alcoholism may be caused by a variety of factors. Genetic, psychological, social and environmental factors may all be part of the cause. Risk factors include steady drinking over time or binge drinking on a regular basis, starting to drink alcohol at a young age, a family history of alcoholism, and suffering from depression, bipolar disorder or anxiety. Alcoholism increases your risk for developing liver damage (cirrhosis), digestive problems, heart problems, sexual dysfunction, birth defects, bone loss, neurological complications and complications with diabetes. Alcoholism can weaken your immune system and increase your risk of certain cancers. Talk to your doctor if you or a family member may have an alcohol addiction. They may ask you a series of questions to determine if you are addicted to alcohol and to rule out other conditions. There are a variety of treatments to help you stop drinking including both inpatient and outpatient programs and private and group counseling. Your doctor can help you decide the best treatment plan for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

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National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

Last Updated: 8 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Alcohol dependence" for support, advocacy or research.

Logo
National Council on Alcoholism and Drug Dependence, Inc. (NCADD)

The National Council on Alcoholism and Drug Dependence, Inc. (NCADD) and its Affiliate Network is a voluntary health organization dedicated to fighting the Nation's #1 health problem -- alcoholism, drug addiction and the devastating consequences of alcohol and other drugs on individuals, families and communities.

https://ncadd.org/

Last Updated: 8 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Alcohol dependence" returned 749 free, full-text research articles on human participants. First 3 results:

Genetic variants in ALDH1B1 and alcohol dependence risk in a British and Irish population: A bioinformatic and genetic study.
 

Author(s): Michael J Way, M Adam Ali, Andrew McQuillin, Marsha Y Morgan

Journal:

 

Alcohol is metabolized in the liver via the enzymes alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Polymorphisms in the genes encoding these enzymes, which are common in East Asian populations, can alter enzyme kinetics and hence the risk of alcohol dependence and ...

Last Updated: 8 Jun 2017

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Lifetime and recent alcohol use and bone mineral density in adults with HIV infection and substance dependence.
 

Author(s): Alicia S Ventura, Michael R Winter, Timothy C Heeren, Meg M Sullivan, Alexander Y Walley, Michael F Holick, Gregory J Patts, Seville M Meli, Jeffrey H Samet, Richard Saitz

Journal: Medicine (Baltimore). 2017 Apr;96(17):e6759.

 

Low bone mineral density (BMD) is common in people living with HIV infection (PLWH), increasing fracture risk. Alcohol use is also common in PLWH and is a modifiable risk factor for both HIV disease progression and low BMD. In PLWH, alcohol's effect on BMD is not well understood.We ...

Last Updated: 26 Apr 2017

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Epidemiology of alcohol dependence in UK primary care: Results from a large observational study using the Clinical Practice Research Datalink.
 

Author(s): Andrew Thompson, Alison K Wright, Darren M Ashcroft, Tjeerd P van Staa, Munir Pirmohamed

Journal:

 

This study aims to investigate the incidence and annual presentation rates of alcohol dependence in general practice in the UK, and examine age-, gender-, socioeconomic-, and region-specific variation. We conducted a retrospective 'open' cohort study using the Clinical Practice Research ...

Last Updated: 31 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Alcohol dependence" returned 93 free, full-text review articles on human participants. First 3 results:

[Neurobiology of Alcohol Dependence and Implications on Treatment].
 

Author(s): Ertuğrul Eşel, Köksal Dinç

Journal: Turk Psikiyatri Derg. 2017 ;28(1):51-60.

 

The process of alcohol dependence has been conceptualized as a progress from controlled alcohol intake to compulsive alcohol consumption or a shift from alcohol intake for pleasure to compulsory alcohol seeking behavior. Hereditary and physical factors and the interaction of individuals ...

Last Updated: 14 Mar 2017

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Reprogramming of mPFC transcriptome and function in alcohol dependence.
 

Author(s): M Heilig, E Barbier, A L Johnstone, J Tapocik, M W Meinhardt, S Pfarr, C Wahlestedt, W H Sommer

Journal: Genes Brain Behav.. 2017 Jan;16(1):86-100.

 

Despite its limited immediate reinforcement value, alcohol has a potent ability to induce neuroadaptations that promote its incentive salience, escalation of voluntary alcohol intake and aversion-resistant alcohol seeking. A constellation of these traits, collectively called 'post-dependent', ...

Last Updated: 22 Sep 2016

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Variation in gastric alcohol dehydrogenase and the risk of alcohol dependence.
 

Author(s): Paulina Całka, Marzanna Ciesielka, Grzegorz Buszewicz, Grzegorz Teresiński

Journal: Arch Med Sadowej Kryminol. ;66(3):172-181.

 

Alcohol dependence is both a medical and socioeconomic problem. The disease is multifactorial, i.e. its development is attributable to gene-gene and gene-environment interactions. Multi-centre studies investigating the genetic background of alcoholism stress the role of genes encoding ...

Last Updated: 28 Apr 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment for Alcohol Dependence With Gabapentin
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 9 Jun 2016

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Study of Familiarity in Alcohol Dependence
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 22 Aug 2017

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Neurofeedback & Alcohol Dependence
 

Status: Recruiting

Condition Summary: Alcohol Dependence

 

Last Updated: 20 Jun 2017

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